EKS-XIM-00051

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XIM-00051

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/RAD53	347.7	4.0E-104	185	448	264

Status

Unreviewed

Ensembl Protein

ENSXMAP00000001234

Gene Name

CHEK2

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXMAG00000001229	ENSXMAP00000001234	ENSXMAT00000001237

Organism

Xiphophorus maculatus

Protein Length

515

Protein Sequence
(FASTA)

MSAESSAEGE PSQNRPPSQQ GSGSSSGPTS ASQSSSGSGT LSSVDTLPVT LPSVPEEAEL 60

QPWGRLLPMA PGFRSHDCVE DRYLFGRDAA CDYVLDDPQD RKSKRFRIYS KKHFRIYREG 120

SEVFVEDYSN NGTFVDGVKV GQNKKLPLTN NAVLSLAEQR NRVFVFIDLM SDYQSSLPRA 180

LQDKYVLTRQ IGTGVCGEVR LAFERSTCRK FAVKIINKKN FQSEGTAKRN AETEIEILQR 240

VDHPCLIKTE DFYQTEDSYY IVLELMEGGE LFHRVKSQQQ LDEGVAKLYF YQMLCAVQYL 300

HRNGIIHRDL KPENILLSSS EDECLIKVTD FNQSRILEEA ALMRTLCGTP SYLAPEVFTH 360

ASSTGYGLAV DAWSLGVLLF VCLSGYTPFH ERFGERSVTE QIIRGEFTMI PSKWRHVSNQ 420

AKDMVRKLLE VDPTLRMTVD EALQHPWLQD QPMQQTAHRL MKPAGGRGDA AAEEDDALSA 480

AVSTEADSSS AGSLNRKRGR GEEEEEHLHP AKRKF 515

Nucleotide Sequence
(FASTA)

ATGTCTGCAG AGAGCTCAGC TGAGGGGGAG CCGTCCCAAA ACCGACCCCC GTCCCAGCAG 60

GGGTCCGGTT CGTCCAGCGG TCCCACCTCG GCCAGCCAGT CGTCCAGCGG CTCTGGGACA 120

CTGAGCAGCG TGGACACGCT TCCCGTCACG CTGCCGTCTG TCCCGGAGGA GGCGGAGCTT 180

CAGCCCTGGG GCCGGCTGCT CCCCATGGCC CCAGGTTTCC GGAGCCACGA CTGCGTGGAG 240

GACCGGTACC TGTTCGGACG GGACGCCGCC TGCGACTACG TCCTGGACGA CCCGCAGGAC 300

AGGAAGTCCA AGAGGTTCAG GATCTACAGC AAGAAGCACT TCAGGATCTA CAGGGAAGGC 360

TCCGAGGTCT TCGTAGAGGA CTACAGTAAC AACGGGACGT TTGTGGACGG GGTGAAGGTC 420

GGCCAGAACA AGAAGCTGCC TCTAACGAAT AACGCCGTCC TTTCTCTGGC TGAGCAGCGC 480

AACAGAGTGT TCGTCTTCAT TGACCTGATG TCCGACTATC AGTCCAGTTT GCCCAGAGCT 540

CTGCAGGACA AATACGTGCT GACCCGCCAG ATCGGAACGG GCGTCTGCGG CGAGGTGCGG 600

CTGGCCTTCG AACGCTCCAC CTGCAGGAAG TTTGCCGTTA AGATCATCAA CAAGAAGAAC 660

TTCCAGTCTG AGGGGACAGC GAAACGGAAC GCAGAGACAG AGATTGAGAT CCTGCAGAGG 720

GTAGATCATC CGTGTCTCAT AAAGACGGAG GACTTCTACC AGACGGAGGA CAGCTACTAC 780

ATCGTCCTGG AGCTCATGGA GGGCGGTGAG CTCTTCCACA GAGTGAAGTC TCAGCAGCAG 840

CTCGATGAAG GCGTGGCCAA GCTTTACTTC TATCAAATGC TCTGTGCCGT GCAGTATCTC 900

CACAGGAACG GGATCATCCA CAGAGATCTG AAGCCAGAGA ACATCCTCCT GTCCTCAAGT 960

GAGGACGAAT GTCTCATCAA GGTGACGGAT TTCAACCAAT CCAGGATCCT GGAGGAGGCG 1020

GCCCTGATGC GGACGCTGTG TGGGACTCCG TCCTACCTGG CCCCTGAGGT CTTCACTCAC 1080

GCCTCCAGCA CCGGTTACGG GCTGGCGGTG GATGCCTGGA GCCTGGGCGT GCTTCTGTTT 1140

GTCTGCCTCA GCGGCTACAC GCCGTTCCAC GAGAGGTTCG GCGAGCGTTC AGTGACGGAG 1200

CAGATCATCC GCGGGGAATT CACCATGATC CCGTCCAAGT GGAGGCACGT CTCCAATCAA 1260

GCCAAAGACA TGGTGAGGAA GCTGCTGGAG GTCGACCCCA CGCTGAGGAT GACTGTGGAT 1320

GAGGCTCTGC AGCACCCCTG GCTGCAGGAC CAGCCGATGC AGCAGACGGC TCACAGGCTC 1380

ATGAAGCCGG CAGGAGGAAG AGGAGATGCT GCTGCTGAAG AAGATGATGC CCTATCTGCT 1440

GCTGTTTCCA CGGAAGCGGA TTCATCCTCA GCAGGAAGTT TAAATCGGAA ACGAGGAAGA 1500

GGAGAGGAGG AAGAGGAGCA TCTTCATCCT GCAAAGAGGA AGTTCTAG 1548

Domain Profile

S: 1     yilskelGkGafgkvklayekktgkkvavkilskrksirssreikkakeveeeveilkkl  60

         y+l +++G+G +g+v+la+e++t++k+avki++k++    ++e + +++ e+e+eil+++

Q: 185   YVLTRQIGTGVCGEVRLAFERSTCRKFAVKIINKKN---FQSEGTAKRNAETEIEILQRV  241

         7899******************************99...555666778899*********

S: 61    shPnivklkdvfeeeeskylvlelvegGelldkvvakkllkedlskllfkqlltavkylh  120

         +hP+++k +d++++e+s+y+vlel+egGel+++v ++++l e ++kl+f+q+l av+ylh

Q: 242   DHPCLIKTEDFYQTEDSYYIVLELMEGGELFHRVKSQQQLDEGVAKLYFYQMLCAVQYLH  301

         ************************************************************

S: 121   ekgiihrDlkPeniLlsekeedvlvkitDfGlakvlgevslmktlCGtpsyvaPevlvkk  180

          +giihrDlkPeniLls+ e+++l+k+tDf ++++l+e  lm+tlCGtpsy+aPev ++

Q: 302   RNGIIHRDLKPENILLSSSEDECLIKVTDFNQSRILEEAALMRTLCGTPSYLAPEVFTHA  361

         ************************************************************

S: 181   graeytskvDiWslGvvlfvilsGypPfseeltqvslkeqilkgkyafieekwkkiseea  240

           ++y  +vD WslGv+lfv+lsGy Pf e+ ++ s++eqi +g++++i++kw+++s++a

Q: 362   SSTGYGLAVDAWSLGVLLFVCLSGYTPFHERFGERSVTEQIIRGEFTMIPSKWRHVSNQA  421

         ************************************************************

S: 241   kdlikklLvvdPeerlsieealnhpWl  267

         kd+++klL vdP+ r++++eal+hpWl

Q: 422   KDMVRKLLEVDPTLRMTVDEALQHPWL  448

         **************************8

Domain Sequence
(FASTA)

YVLTRQIGTG VCGEVRLAFE RSTCRKFAVK IINKKNFQSE GTAKRNAETE IEILQRVDHP 60

CLIKTEDFYQ TEDSYYIVLE LMEGGELFHR VKSQQQLDEG VAKLYFYQML CAVQYLHRNG 120

IIHRDLKPEN ILLSSSEDEC LIKVTDFNQS RILEEAALMR TLCGTPSYLA PEVFTHASST 180

GYGLAVDAWS LGVLLFVCLS GYTPFHERFG ERSVTEQIIR GEFTMIPSKW RHVSNQAKDM 240

VRKLLEVDPT LRMTVDEALQ HPWL 264

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>