EKS-XIM-00261

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XIM-00261

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	440.4	2.1E-132	10	294	285

Status

Unreviewed

Ensembl Protein

ENSXMAP00000002017

Gene Name

CDKL5 (1 of 2)

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXMAG00000002007	ENSXMAP00000002017	ENSXMAT00000002022

Organism

Xiphophorus maculatus

Protein Length

1116

Protein Sequence
(FASTA)

PALCDVMNKF EVLGIVGEGA YGVVLKCRHK ETNELVAIKK FKDSEENEEV KETTLRELKM 60

LRTLKQDNIV ELKEAFRRRG KLYLVFEYVE RNMLELLEEF PNGAPPEKVR SYIFQLIKAI 120

NWCHKNEIVH RDIKPENLLI SSDDVLKLCD FGFARNLSEG TDANYTEYVA TRWYRSPELL 180

LGAPYGKAVD MWSVGCILGE LSDGQPLFPG ESEIDQLFTI QKVLGPLPAE QMKLFYNNPR 240

FHGIRFPTVT HPQTLERRYQ GIMSGLMLDL MKSMLLLNPT ERFLTEQCLN HPAFQPFRQA 300

EREKSSPASP NPPRSSKRKT HHHGENTVPT RSHTKSSSRR STSKECSSLP RHGDLHHLSN 360

ESFLNGNKPA PSSLSPTLHP KVQYMSQTLN RSASSNKDLA NNNLPHLLSP KEAKNKTEFD 420

FNLGPSTKLS DQGHGAKYTH SKPNSSRHTF LENKTNTLQS GAEKQHGRHA HSMADSAHGS 480

MSSSSKSSAS YLSLSKSHGA LSDAKSVGNL SDGRLHPDDP NANATAVVGP SARFFPASCL 540

DLNAPSGLPG PPGSPSTRHS DRSGHSPASR SSVNVRMESS TLDSSSRHKS RHKSLAPEDA 600

GAPELLDPGG PAMPNTHTLP SPHESYHYGL GYTSPFSSQQ RPQRHSMYVR RERHRPHGSE 660

GVMAGLPPPG QVIPTRASSL QLLSPQLQHR TNLTGHSVSS SREDCTDDMT RSEQPPKDMS 720

HPCAPIKDST RDNSAAFHTQ RSKNEVGMYH DPHGEDAGSS KENRMIFTES MPRRVGSFYR 780

VPSPRPDNSS SFHEGVGQGR GPGVPVVAGD PGGMANHSKR QTAFDWTAAE AMVMNPPEPT 840

KEKQKQGFFK AIKKKKKKTQ ITDVEDGRNP SIKKSLFPLF SSKNSLKHNS AGKILPVVAS 900

PMVTGNGQEH LSLQRSSKSS SHHSSRRKNR ERSRDRDHDR EQSRDRERER ENKRERERER 960

GRERERVTDW PPEKPVDSHS QSQPLKSLRR LLHLSPSPSN QGQPPPPPPP DLRFQAPLPN 1020

PPQSSSKVGY PEGRGHTESR GHSGMSSSGQ AKNRKASYTL PGQIESSWHV SALQRVEGAQ 1080

FTPEQLGIKP GQNGPTFTRA SRTRMPNLND LKETAL 1116

Nucleotide Sequence
(FASTA)

CCCGCTCTCT GTGATGTGAT GAATAAGTTT GAAGTCCTTG GCATTGTGGG AGAAGGTGCA 60

TATGGAGTGG TGCTTAAATG CAGACATAAG GAAACAAATG AGCTGGTGGC CATCAAGAAG 120

TTCAAAGACA GTGAAGAAAA TGAGGAGGTT AAGGAGACGA CCCTTCGGGA GCTGAAGATG 180

CTCCGGACCC TGAAGCAGGA CAACATCGTC GAGCTCAAAG AGGCTTTTCG CAGGAGGGGG 240

AAACTCTACC TCGTCTTTGA ATATGTTGAG AGGAACATGC TTGAACTGCT AGAGGAATTT 300

CCCAATGGTG CACCGCCGGA AAAAGTTCGC AGCTACATTT TCCAGCTCAT CAAAGCCATC 360

AACTGGTGTC ACAAAAATGA AATTGTTCAC AGAGATATCA AACCAGAAAA TCTTCTTATC 420

AGTTCAGATG ATGTTCTTAA ACTATGTGAC TTTGGGTTTG CTCGTAACCT GTCTGAAGGA 480

ACAGATGCCA ACTACACCGA GTATGTGGCC ACCAGGTGGT ACCGCTCACC TGAGCTGCTG 540

CTGGGGGCTC CCTATGGAAA GGCTGTGGAC ATGTGGTCGG TGGGGTGTAT TCTGGGGGAG 600

CTGAGTGACG GACAGCCTTT GTTTCCAGGG GAAAGCGAGA TTGATCAGCT CTTCACCATC 660

CAGAAAGTTC TGGGTCCTCT TCCTGCTGAA CAGATGAAAC TCTTTTACAA CAACCCGCGA 720

TTTCATGGAA TCAGGTTTCC CACAGTTACC CATCCTCAGA CTTTGGAGAG ACGGTACCAG 780

GGAATTATGA GTGGTTTGAT GTTGGATTTG ATGAAGAGCA TGTTGCTGCT GAACCCTACC 840

GAGCGTTTTC TAACCGAGCA GTGTTTGAAC CATCCTGCTT TCCAGCCTTT CAGGCAGGCG 900

GAGAGAGAAA AATCTTCTCC CGCTTCTCCA AACCCACCAC GCTCGTCCAA GAGAAAAACA 960

CACCACCACG GAGAAAATAC AGTCCCTACA AGGAGTCACA CCAAGAGCTC AAGTCGTCGA 1020

TCAACCAGTA AGGAATGTTC CAGCCTCCCT CGCCATGGAG ACCTGCATCA CCTCAGCAAT 1080

GAGAGTTTTC TGAATGGTAA CAAACCGGCT CCATCTAGTT TAAGTCCTAC ACTCCACCCG 1140

AAAGTCCAGT ACATGTCCCA GACCCTAAAT CGTTCAGCCT CGTCCAACAA AGATCTGGCT 1200

AACAACAACC TGCCACACCT TCTCAGTCCC AAAGAGGCAA AAAACAAGAC AGAGTTTGAT 1260

TTCAACTTGG GGCCCTCAAC AAAGCTGTCA GATCAGGGAC ATGGGGCAAA GTACACGCAC 1320

AGCAAACCAA ACTCGTCTCG GCACACCTTT CTGGAAAATA AAACCAACAC ATTACAGTCT 1380

GGAGCAGAAA AACAACATGG CCGCCATGCC CACAGCATGG CAGACTCTGC ACATGGATCC 1440

ATGTCGTCCT CTTCTAAAAG TTCAGCTTCT TATCTAAGCC TGTCCAAGAG TCATGGGGCT 1500

CTTAGCGACG CCAAATCTGT GGGGAACCTA AGCGATGGTC GACTTCACCC AGACGACCCA 1560

AATGCAAATG CAACAGCCGT TGTAGGACCC AGTGCCCGTT TCTTCCCTGC CAGCTGTTTG 1620

GACCTCAACG CCCCGTCGGG TCTTCCAGGA CCCCCCGGCA GTCCCTCGAC TCGACACAGT 1680

GACCGATCAG GACACAGCCC CGCTTCCCGT AGCAGCGTAA ATGTACGTAT GGAGAGCAGC 1740

ACGTTGGATT CCTCATCGAG ACACAAGTCC AGACACAAAT CGTTGGCTCC AGAAGACGCT 1800

GGTGCTCCAG AGCTCCTAGA CCCAGGAGGA CCGGCGATGC CCAACACTCA CACCCTGCCT 1860

TCCCCCCACG AGTCTTATCA CTACGGCCTT GGCTACACGT CCCCCTTTTC CTCCCAGCAA 1920

CGGCCTCAGC GCCACTCCAT GTACGTGAGA CGGGAACGTC ACCGACCACA TGGGTCTGAG 1980

GGGGTCATGG CGGGCCTGCC GCCGCCTGGA CAGGTCATAC CGACTCGGGC CAGCAGCCTC 2040

CAACTCCTCT CCCCACAGCT GCAACACCGT ACCAACCTGA CTGGACATTC AGTGAGCTCG 2100

TCGAGAGAGG ACTGCACCGA CGACATGACG AGGAGTGAAC AGCCCCCTAA AGACATGAGC 2160

CACCCTTGTG CCCCCATCAA AGACTCTACG AGGGACAACT CCGCTGCTTT TCATACACAG 2220

CGCTCTAAAA ATGAGGTCGG TATGTATCAT GACCCTCACG GTGAGGATGC AGGTTCCTCC 2280

AAGGAAAACC GGATGATCTT CACTGAGTCC ATGCCTCGGA GAGTCGGCAG CTTCTACAGA 2340

GTCCCTTCCC CCAGACCGGA TAACTCCTCT TCTTTCCACG AAGGTGTTGG TCAGGGAAGA 2400

GGGCCTGGTG TACCCGTTGT GGCCGGTGAT CCAGGCGGCA TGGCGAACCA CTCCAAACGC 2460

CAGACGGCTT TTGATTGGAC TGCTGCAGAA GCAATGGTCA TGAATCCTCC AGAGCCCACC 2520

AAAGAGAAGC AAAAACAAGG CTTCTTCAAA GCCATTAAAA AGAAAAAGAA GAAGACACAA 2580

ATAACGGACG TGGAGGACGG AAGGAATCCG AGCATCAAGA AAAGCCTTTT CCCCCTTTTT 2640

AGCTCTAAGA ATAGCTTAAA GCACAACTCA GCTGGAAAAA TCCTACCTGT AGTTGCCTCG 2700

CCTATGGTTA CTGGGAATGG ACAGGAACAC CTTTCCCTTC AGAGGAGCTC CAAGTCGTCC 2760

TCCCACCACA GCAGCAGACG GAAAAACCGC GAGCGATCCC GGGACAGAGA CCACGACCGG 2820

GAACAGAGCA GGGACAGAGA GCGGGAGAGA GAAAACAAGA GGGAGAGAGA GAGGGAGAGG 2880

GGGAGGGAAA GAGAGAGAGT CACTGATTGG CCACCAGAAA AGCCAGTAGA CTCCCACTCT 2940

CAGAGCCAAC CTCTGAAGTC TCTACGTCGA CTCCTTCACC TCTCGCCTTC CCCCTCAAAC 3000

CAAGGGCAGC CTCCTCCTCC ACCTCCTCCG GACCTGCGCT TCCAAGCCCC CCTCCCCAAC 3060

CCGCCTCAGT CCTCCTCCAA AGTCGGCTAC CCAGAGGGTC GAGGGCACAC GGAGAGCAGG 3120

GGCCACTCGG GGATGAGCAG CTCAGGCCAG GCGAAGAACC GCAAGGCCAG CTACACCTTA 3180

CCGGGACAGA TCGAATCCAG CTGGCACGTG TCGGCTTTAC AGCGGGTGGA AGGCGCTCAG 3240

TTTACTCCAG AACAGCTGGG CATCAAACCG GGTCAGAACG GACCTACTTT TACCCGAGCA 3300

TCCCGCACCA GGATGCCAAA TCTCAACGAT CTGAAGGAGA CAGCCCTGTA A 3351

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         +e lg vGeG+yGvvlkcr+k+t+++vaikkf++se+++evk+++lre+k+l++lk++n+

Q: 10    FEVLGIVGEGAYGVVLKCRHKETNELVAIKKFKDSEENEEVKETTLRELKMLRTLKQDNI  69

         799*********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         v+l+e+frr+ klylvfeyv++++l+ le++pnG + e+v+++++q++kai++chkn+i+

Q: 70    VELKEAFRRRGKLYLVFEYVERNMLELLEEFPNGAPPEKVRSYIFQLIKAINWCHKNEIV  129

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarlla.apgdvytdyvatrwyrapellvgdtkyGks  179

         hrdikpen+lis ++v+klcdfGfar+l+ +++++yt+yvatrwyr+pell+g + yGk+

Q: 130   HRDIKPENLLISSDDVLKLCDFGFARNLSeGTDANYTEYVATRWYRSPELLLG-APYGKA  188

         ****************************978899*******************.9*****

S: 180   vdvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpe  239

         vd+w++Gc+l el++G+plfpg+s++dql++i+k+lG+l ++++k+f++n++f+G+++p+

Q: 189   VDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPAEQMKLFYNNPRFHGIRFPT  248

         ************************************************************

S: 240   vedleslekkyp.klnevlldllkkclkldpaerlsceellkheyf  284

         v ++++le++y+  ++ ++ldl+k++l l+p+er+++e++l+h+ f

Q: 249   VTHPQTLERRYQgIMSGLMLDLMKSMLLLNPTERFLTEQCLNHPAF  294

         ***********978899**************************987

Domain Sequence
(FASTA)

FEVLGIVGEG AYGVVLKCRH KETNELVAIK KFKDSEENEE VKETTLRELK MLRTLKQDNI 60

VELKEAFRRR GKLYLVFEYV ERNMLELLEE FPNGAPPEKV RSYIFQLIKA INWCHKNEIV 120

HRDIKPENLL ISSDDVLKLC DFGFARNLSE GTDANYTEYV ATRWYRSPEL LLGAPYGKAV 180

DMWSVGCILG ELSDGQPLFP GESEIDQLFT IQKVLGPLPA EQMKLFYNNP RFHGIRFPTV 240

THPQTLERRY QGIMSGLMLD LMKSMLLLNP TERFLTEQCL NHPAF 285

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>