EKS-XIM-00510

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XIM-00510

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/IRAK	289.7	2.4E-86	187	475	289

Status

Unreviewed

Ensembl Protein

ENSXMAP00000003526

Gene Name

IRAK1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXMAG00000003511	ENSXMAP00000003526	ENSXMAT00000003531

Organism

Xiphophorus maculatus

Protein Length

716

Protein Sequence
(FASTA)

MSEGDPRTYF LFQLPSSVHC EFCRVMDGLL DLDWTRFASE ILRDQTAVRL AYRREQRTDW 60

VMNNWGNRNG RVGELVDLLE SLQLFRPRDI ILSWMQNLSC PPPLPPALPP PPYEPSAAQS 120

TAECPDRKPL PGPAPPPINL FSENHRPPPR LPAATDDVMP PSPSPCGAIT TIICWTYEEV 180

HAGTRGFSPS LQVGEGGFGV VYRATLSNMD CAVKRLRQDG QMDWTLLRKS FQTEVENLSK 240

FRHPNIVDLL GFSEGEGGLM CLIYSYMQNR SLEDQLQNAL GLSWPDRVSI IEGAAAALQF 300

LHRPPSRQEP LIHGDVKSSN ILLDQHLVPK LSDFGLARYV PQNSAGCSTQ TASVGKTTTV 360

RGTLAYLPDE YVRRGELCTA VDVYSYGVVL LEVLTGRRAL EQDERTGDRF LRDLVEEVDD 420

GKKGSAPDAW RRHLDQRLTA GGAAEPEGYL QVAALARKCL NRQRKKRPAM TEVFCHLKDL 480

CCVVRKNSSS SSAPRLPQQP YHSFPKPPRS LDSCVKAISQ QLSRLGPSEQ TCPSSQYDSS 540

SSSSSSSFGA LAPPHPLQSC LGSVSPSSSP CPSLAGPCET DESRGFSQYD FQFRSNGTSC 600

RTQSQNPAGS AESQLTQPSV PTEDLYNFPS SPSSGAGPAA AGFSPARSLQ STTAGLSVLV 660

NPSKQRLLEQ KSRYEAGWIR TPELLSLDDL YGGRSAADLR GPEESDELEY LPSGRS 716

Nucleotide Sequence
(FASTA)

ATGTCAGAGG GAGACCCGCG GACTTACTTC CTGTTCCAGC TGCCCTCCTC GGTCCACTGC 60

GAATTCTGCC GGGTCATGGA TGGACTGCTG GACCTGGACT GGACCCGGTT CGCCTCGGAG 120

ATCCTCAGAG ACCAGACGGC GGTGCGCCTG GCCTACCGGA GGGAGCAGCG GACCGACTGG 180

GTCATGAACA ACTGGGGCAA CAGGAACGGC CGAGTCGGGG AGTTGGTTGA CCTTCTGGAG 240

TCTCTGCAGC TTTTCAGACC GCGGGACATC ATCCTGAGCT GGATGCAGAA CCTGAGTTGT 300

CCTCCTCCCC TTCCTCCCGC TCTTCCTCCT CCTCCGTACG AACCGTCGGC AGCTCAGTCC 360

ACAGCTGAGT GTCCAGACAG GAAGCCGCTG CCTGGCCCGG CCCCGCCCCC TATCAACCTG 420

TTCTCTGAGA ACCATCGCCC CCCCCCCAGG CTCCCCGCCG CTACTGATGA TGTCATGCCT 480

CCATCTCCAT CGCCATGCGG CGCCATCACC ACCATCATCT GCTGGACATA TGAAGAGGTG 540

CATGCTGGGA CGCGAGGCTT CTCCCCCAGC CTTCAGGTTG GCGAGGGCGG CTTCGGCGTT 600

GTTTACCGAG CGACGCTCAG CAACATGGAC TGCGCCGTCA AGAGACTCCG ACAGGACGGC 660

CAGATGGACT GGACTCTCCT CAGGAAAAGC TTCCAGACTG AAGTGGAGAA CCTGTCCAAG 720

TTCAGACATC CCAACATCGT AGACCTGCTG GGCTTCAGTG AAGGAGAGGG AGGACTGATG 780

TGTCTGATCT ACAGCTACAT GCAGAACCGC TCCCTGGAGG ACCAGCTGCA GAACGCGCTG 840

GGTCTCTCGT GGCCCGACCG GGTCAGCATC ATTGAAGGAG CGGCAGCAGC TCTTCAGTTC 900

CTGCACCGCC CGCCGTCGCG TCAGGAGCCG CTGATCCATG GAGACGTCAA GAGTTCTAAC 960

ATCCTGTTGG ACCAGCATCT GGTACCAAAG CTTTCGGACT TCGGTCTGGC CCGGTACGTA 1020

CCGCAGAACT CGGCCGGCTG CTCGACGCAG ACGGCTTCCG TCGGCAAAAC CACGACAGTG 1080

AGAGGAACGC TGGCCTATCT GCCCGACGAG TACGTGAGGA GAGGAGAGCT GTGCACAGCG 1140

GTGGACGTCT ACAGCTACGG AGTGGTGCTG CTTGAGGTTC TGACGGGCCG CCGAGCTCTG 1200

GAGCAGGACG AGAGGACAGG AGACCGATTC CTGAGGGACC TTGTGGAGGA AGTTGATGAC 1260

GGTAAAAAAG GTTCAGCCCC AGATGCCTGG AGGAGACACC TGGATCAACG GCTGACTGCA 1320

GGGGGCGCCG CTGAGCCTGA AGGGTACCTG CAGGTGGCAG CGTTGGCCAG AAAGTGTCTG 1380

AACAGGCAGA GGAAGAAGAG ACCTGCAATG ACTGAGGTCT TCTGCCACCT GAAGGACCTC 1440

TGCTGCGTTG TGAGGAAGAA CTCCTCCTCT TCCTCGGCGC CCCGGCTCCC CCAGCAGCCC 1500

TACCATTCCT TCCCCAAACC CCCCCGCTCC CTGGACTCCT GTGTTAAAGC CATCTCTCAG 1560

CAGCTGTCCA GACTGGGACC ATCAGAACAG ACCTGCCCTT CCTCCCAGTA CGACTCTTCC 1620

TCCTCCTCTT CTTCCTCGTC GTTTGGGGCC CTCGCCCCGC CTCACCCGCT GCAGTCCTGT 1680

CTCGGTTCTG TCTCCCCCTC GTCTTCCCCT TGCCCCTCGC TCGCTGGCCC ATGCGAAACT 1740

GACGAGAGCC GGGGGTTCTC TCAGTACGAC TTTCAGTTCC GGTCCAACGG AACCAGCTGC 1800

AGGACCCAGA GCCAGAACCC AGCTGGGTCT GCAGAGTCCC AGCTGACCCA GCCCTCTGTT 1860

CCCACCGAGG ACCTGTACAA CTTCCCATCC TCTCCCAGCA GCGGCGCCGG ACCGGCGGCG 1920

GCTGGGTTTT CCCCGGCGCG GTCGTTGCAG TCCACCACAG CCGGACTCTC AGTTCTTGTG 1980

AATCCCAGCA AACAGCGACT GTTGGAGCAG AAGAGTCGGT ACGAAGCGGG TTGGATCAGA 2040

ACCCCAGAAC TGCTGTCCTT GGACGACCTC TACGGAGGGA GGAGCGCTGC AGATCTCCGA 2100

GGACCGGAGG AGAGCGATGA GCTGGAGTAT CTTCCCTCCG GTCGCTCCTG A 2151

Domain Profile

S: 1     fsednrigeGgfgevyrgelkntavavkklkeeadlslkelkqsfltElkvlarfrHdni  60

         fs + ++geGgfg+vyr++l n++ avk+l++  +++++ l++sf+tE++ l++frH+ni

Q: 187   FSPSLQVGEGGFGVVYRATLSNMDCAVKRLRQDGQMDWTLLRKSFQTEVENLSKFRHPNI  246

         78899*******************************************************

S: 61    lellgysa.eseklcLvYqymknGsLedrLqcqkgsepLsWpqRlsillGtaraiefLHe  119

         ++llg+s  e++ +cL+Y+ym+n sLed+Lq    +  LsWp R+si+ G+a a++fLH+

Q: 247   VDLLGFSEgEGGLMCLIYSYMQNRSLEDQLQN---ALGLSWPDRVSIIEGAAAALQFLHR  303

         *******7467899****************75...567*********************7

S: 120   ...aspslihgdiksaNiLLDekltpKlgDfglarfapese....kqsstvlrtskvrgt  172

             +++lihgd+ks+NiLLD++l pKl+Dfglar+ p++      q+  v +t +vrgt

Q: 304   ppsRQEPLIHGDVKSSNILLDQHLVPKLSDFGLARYVPQNSagcsTQTASVGKTTTVRGT  363

         3324559****************************766664111156677999*******

S: 173   laYlpeefirvgqltvkvDvySfGiVllEvltGlravdedrkt..kyLkdllkeeieeek  230

         laYlp+e++r g+l + vDvyS+G+VllEvltG+ra ++d++t  + L+dl++e  + +k

Q: 364   LAYLPDEYVRRGELCTAVDVYSYGVVLLEVLTGRRALEQDERTgdRFLRDLVEEVDDGKK  423

         ************************************66666543389****866544433

S: 231   v...eilekfldkka...gkleeellealielalaclaekakkrPtmsqvle  276

             +  +++ld++    g +e+e   +++ la +cl++++kkrP m++v

Q: 424   GsapDAWRRHLDQRLtagGAAEPEGYLQVAALARKCLNRQRKKRPAMTEVFC  475

         356699*******9833345699999999********************975

Domain Sequence
(FASTA)

FSPSLQVGEG GFGVVYRATL SNMDCAVKRL RQDGQMDWTL LRKSFQTEVE NLSKFRHPNI 60

VDLLGFSEGE GGLMCLIYSY MQNRSLEDQL QNALGLSWPD RVSIIEGAAA ALQFLHRPPS 120

RQEPLIHGDV KSSNILLDQH LVPKLSDFGL ARYVPQNSAG CSTQTASVGK TTTVRGTLAY 180

LPDEYVRRGE LCTAVDVYSY GVVLLEVLTG RRALEQDERT GDRFLRDLVE EVDDGKKGSA 240

PDAWRRHLDQ RLTAGGAAEP EGYLQVAALA RKCLNRQRKK RPAMTEVFC 289

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>