EKS-XIM-00505

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XIM-00505

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/PDGFR	539.4	4.3E-162	590	944	355

Status

Unreviewed

Ensembl Protein

ENSXMAP00000008599

Gene Name

PDGFRB (1 of 2)

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXMAG00000008554	ENSXMAP00000008599	ENSXMAT00000008612

Organism

Xiphophorus maculatus

Protein Length

1102

Protein Sequence
(FASTA)

MRRLIASVLH LMVALTALVH FCPEVRSLEI TPDDKEFVLA QGSSLTLICS GSSHAKWALK 60

RDDSTYYLNQ LDENMKSRYK IFDLDTTSVA LNLTSVSWVH TGVYQCVDDI ADMIKEVAVF 120

VPDPEVWFVK SAHGMVTKTS EESIVPCVAT NPNITVILYE WDTNRPIKGH YVPSEGYRAQ 180

LEDRAYVCRG ELNGEVKESQ EFNVISIIVA EDINPYINSS KTVLKQGEPL TINCTVHGVE 240

LVDFSWDIPH TAVVKVKPQT YFSPKMHSCL TFPRTTVENS GNYVCHVQEM VAGVKASSSV 300

NINVLEHGFV EVKPAQWQNI SAKLQENVEL RVDIEAYPPP QVRWTKDGTT IRGDKAITIR 360

QDHEIRYVTV LTLVRVRTEH NGIYTVIISN GDDRKEIIFD LEVQVPAQIK DLTDHHFPGM 420

RDVVTCVAEG FPAPIIQWYS CDGMLKCSNR TAAWQPLKPQ PEVVSIQTNV NNSQARKVSV 480

VRSQVIFHNP QQITVRCEAS NQPGDVSTRD VKLVSSTWFS KVAVLAAVLA LVVIFILSII 540

ILIAVWRKKP RYEIRWKVIE SVSQDGHEYI YVDPIHLPYD LAWEMPRENL VLGRTLGSGA 600

FGRVVEATAY GLTQSHSSTK VAVKMLKSTA RRSETQALMS ELKIMSHLGP HLNIVNLLGA 660

CTKHGPLYLV TEYCRYGDLV DYLHRNKHTF LQYYAEKNQD SGCIISRGST PLSQRKGYVS 720

FGSESDGGYM DMSKDEPSFY VPMQEQLDTI KYADIQPSPY ESPYQQDLYQ EQGGGRLDLV 780

IGDSPTLTYD DLLGFSYQVA KGMDFLASKN CVHRDLAARN VLICEGKLVK ICDFGLARDI 840

MHDSNYISKG STFLPLKWMA PESIFHNLYT TLSDVWSYGI LLWEIFTLGG TPYPDLPMNE 900

IFYSALKRGY RMAKPAHASD EVYEIMKKCW DEKFEKRPEF SLLVHNVGNM LMDSYKKRYN 960

QVNENFLKSD HPAVARTKPR LSSPFPIANP AFGSPSPITQ SFLGRHSQSP RPGDGGREAD 1020

TQEVIPSYNE YIIPLPDLKP DDVFTEVPSE SPASSLAVEE EADSTSQDTA ETLPEEDRVE 1080

NTSERDALLG SMGTPEVEDS FL 1102

Nucleotide Sequence
(FASTA)

ATGAGGAGGC TGATAGCGTC TGTGCTCCAC CTGATGGTCG CTTTAACGGC TTTGGTGCAT 60

TTCTGCCCAG AAGTGCGCAG CCTGGAGATC ACCCCTGATG ACAAAGAGTT TGTCCTGGCT 120

CAAGGCTCAT CTCTCACCCT AATCTGCTCC GGCTCCAGCC ACGCAAAGTG GGCGCTTAAG 180

AGGGACGATT CAACTTACTA CCTGAACCAG CTAGATGAGA ACATGAAATC AAGATACAAA 240

ATCTTTGATC TTGATACTAC GTCGGTTGCT CTGAACCTAA CAAGTGTGAG TTGGGTGCAT 300

ACTGGCGTGT ATCAGTGCGT CGATGATATT GCTGACATGA TAAAGGAAGT GGCAGTGTTT 360

GTCCCAGATC CTGAAGTTTG GTTTGTAAAG AGCGCCCACG GCATGGTGAC GAAGACCAGT 420

GAAGAAAGCA TCGTCCCCTG TGTGGCCACC AACCCAAACA TCACTGTCAT CCTGTATGAG 480

TGGGACACCA ACAGGCCCAT CAAAGGGCAT TATGTACCGA GTGAGGGGTA CAGGGCGCAG 540

CTGGAGGACA GAGCATATGT GTGCCGTGGA GAGCTGAATG GGGAGGTCAA AGAGTCTCAG 600

GAGTTTAACG TCATCAGCAT TATAGTGGCC GAAGACATCA ACCCTTACAT CAACAGTTCA 660

AAGACGGTCC TGAAGCAGGG CGAGCCGCTG ACTATAAACT GCACGGTGCA CGGAGTGGAG 720

CTGGTGGATT TTTCTTGGGA TATTCCACAC ACTGCGGTTG TTAAGGTTAA ACCACAAACG 780

TATTTCTCCC CGAAGATGCA CTCCTGCCTG ACCTTCCCTC GCACTACGGT GGAGAACAGT 840

GGAAACTACG TGTGCCACGT CCAAGAAATG GTAGCGGGCG TCAAAGCTTC TTCAAGCGTC 900

AACATCAACG TGCTTGAACA CGGTTTTGTG GAGGTGAAAC CTGCTCAGTG GCAAAACATT 960

TCAGCCAAGC TTCAGGAGAA CGTGGAGCTG AGAGTGGACA TTGAGGCCTA CCCTCCCCCT 1020

CAGGTTCGCT GGACCAAAGA CGGGACCACC ATCAGGGGAG ACAAAGCTAT CACAATCAGA 1080

CAGGATCATG AAATAAGGTA TGTGACCGTT CTCACACTGG TGAGGGTGAG GACTGAGCAT 1140

AATGGCATCT ACACGGTCAT CATTTCCAAT GGAGACGACA GAAAGGAAAT TATCTTTGAC 1200

CTGGAAGTCC AAGTTCCTGC TCAGATTAAA GACCTGACCG ACCACCATTT CCCAGGGATG 1260

AGAGACGTGG TGACCTGCGT CGCTGAAGGG TTTCCAGCTC CGATCATACA ATGGTACAGC 1320

TGTGACGGCA TGCTCAAGTG TAGCAACAGG ACAGCAGCAT GGCAGCCGCT GAAGCCACAA 1380

CCGGAGGTGG TGAGCATCCA AACCAATGTC AACAACAGCC AGGCGCGTAA AGTCAGCGTG 1440

GTGAGGAGCC AGGTGATCTT CCATAATCCT CAGCAGATCA CAGTTCGCTG CGAGGCCTCC 1500

AACCAGCCCG GTGACGTCAG CACGAGGGAC GTCAAACTTG TGTCCAGCAC GTGGTTCTCC 1560

AAGGTGGCAG TGCTGGCTGC TGTTCTGGCC TTAGTGGTCA TTTTTATTTT GTCGATAATC 1620

ATCCTCATCG CTGTATGGAG GAAGAAACCT CGCTATGAAA TCAGATGGAA GGTGATAGAG 1680

TCTGTGAGCC AGGATGGACA TGAGTACATT TATGTGGACC CCATCCATCT GCCCTATGAC 1740

CTGGCCTGGG AGATGCCCAG AGAAAACCTG GTGCTGGGTC GCACGCTTGG ATCAGGAGCA 1800

TTTGGCAGGG TGGTCGAGGC AACTGCGTAC GGTCTCACGC AATCCCACTC CAGCACAAAG 1860

GTGGCAGTGA AAATGCTGAA ATCCACAGCC AGGAGGAGTG AGACTCAGGC CCTGATGTCC 1920

GAGCTGAAGA TCATGAGTCA CCTGGGACCT CACCTCAACA TTGTTAACCT GCTCGGAGCC 1980

TGCACCAAAC ATGGCCCTCT CTACCTGGTT ACTGAGTACT GTCGCTATGG TGACCTAGTG 2040

GACTACCTGC ATAGGAACAA GCACACCTTC CTGCAGTACT ACGCTGAGAA GAACCAGGAC 2100

AGCGGATGCA TCATCTCCAG AGGAAGTACC CCTCTCAGCC AGAGAAAAGG CTATGTGTCC 2160

TTCGGAAGTG AGAGCGACGG AGGATACATG GACATGAGCA AAGATGAGCC CTCCTTCTAC 2220

GTGCCTATGC AGGAGCAGCT GGACACAATT AAATATGCAG ACATCCAGCC GTCCCCGTAT 2280

GAATCCCCCT ACCAACAGGA CCTCTACCAG GAACAAGGTG GGGGCAGACT GGATCTGGTG 2340

ATCGGCGATT CTCCCACCCT CACCTACGAC GATCTCCTAG GCTTCAGTTA CCAGGTTGCA 2400

AAGGGAATGG ACTTCCTGGC CTCAAAGAAT TGTGTCCATC GTGACCTGGC AGCCAGGAAT 2460

GTATTGATCT GTGAGGGCAA GCTGGTGAAG ATCTGTGACT TTGGCCTGGC CAGGGACATC 2520

ATGCATGATT CCAACTACAT CTCCAAAGGC AGCACATTCC TGCCCCTGAA GTGGATGGCA 2580

CCGGAAAGCA TTTTCCACAA TTTGTACACC ACCCTGAGCG ACGTTTGGTC ATATGGCATT 2640

CTTCTTTGGG AAATTTTCAC TCTGGGAGGA ACTCCTTACC CTGATTTGCC CATGAATGAA 2700

ATCTTCTACA GTGCTTTGAA GAGAGGCTAC AGGATGGCCA AGCCTGCTCA CGCCTCTGAC 2760

GAAGTGTATG AGATCATGAA GAAGTGCTGG GATGAGAAAT TTGAGAAGAG GCCCGAGTTT 2820

TCCCTCCTGG TGCACAATGT GGGAAACATG CTGATGGACA GCTATAAAAA GAGATACAAC 2880

CAAGTGAATG AAAACTTCCT CAAGAGCGAT CACCCTGCCG TGGCTCGCAC CAAACCTCGG 2940

CTCTCCTCTC CATTTCCAAT TGCCAACCCA GCCTTCGGCT CTCCCTCTCC AATCACTCAG 3000

TCCTTCCTGG GCCGCCACAG CCAGAGCCCG AGGCCTGGAG ACGGCGGGCG AGAGGCAGAC 3060

ACACAGGAAG TCATCCCTTC ATACAACGAG TACATCATTC CTCTCCCAGA CCTAAAGCCT 3120

GACGACGTTT TCACTGAAGT GCCGTCGGAA AGCCCTGCGA GCTCTCTGGC TGTGGAGGAG 3180

GAGGCTGACT CCACATCTCA GGACACGGCG GAAACTCTTC CGGAGGAAGA CCGGGTGGAG 3240

AACACGAGTG AGAGGGACGC ACTGCTGGGC TCCATGGGGA CGCCTGAGGT AGAAGACAGT 3300

TTCCTGTAG 3309

Domain Profile

S: 1     lelGkvlGsGafGkvveatayGlsksdavlkvavkmlkstarssekealmselkilshlG  60

         l+lG++lGsGafG+vveatayGl++s+++ kvavkmlkstar se +almselki+shlG

Q: 590   LVLGRTLGSGAFGRVVEATAYGLTQSHSSTKVAVKMLKSTARRSETQALMSELKIMSHLG  649

         78**********************************************************

S: 61    ehenivnllGactkgGpiyviteyccyGdllnylrrkresflkkslekkkekeeeldska  120

         +h+nivnllGactk Gp+y++teyc+yGdl++yl+r++++fl+ ++ek++++   ++  +

Q: 650   PHLNIVNLLGACTKHGPLYLVTEYCRYGDLVDYLHRNKHTFLQYYAEKNQDSGCIISRGS  709

         ************************************************988877777666

S: 121   lladkslrsksslssesseeyvdlkkd................vsdvssskadklasekk  164

          +  ++ + ++s+ ses++ y+d++kd                ++d+++s ++++++++

Q: 710   TPL-SQRKGYVSFGSESDGGYMDMSKDepsfyvpmqeqldtikYADIQPSPYESPYQQDL  768

         554.45688999***********************************************8

S: 165   ksalerevkaaleeedsevleledllsfsyqvakGmeflaskncvhrdlaarnvllteGk  224

          + +   + + ++ + s +l+++dll fsyqvakGm+flaskncvhrdlaarnvl++eGk

Q: 769   YQEQGGGRLDLVIGD-SPTLTYDDLLGFSYQVAKGMDFLASKNCVHRDLAARNVLICEGK  827

         877777777766665.9*******************************************

S: 225   vvkicdfGlardimkdsnyvvkGnarlpvkwmapesifdslytvksdvwsyGillweifs  284

         +vkicdfGlardim+dsny++kG+++lp+kwmapesif++lyt+ sdvwsyGillweif+

Q: 828   LVKICDFGLARDIMHDSNYISKGSTFLPLKWMAPESIFHNLYTTLSDVWSYGILLWEIFT  887

         ************************************************************

S: 285   lGstpypgllvdskfyklikeGyrmaqpayateeiyeimqkcweaepekrpsfkqlv  341

         lG+tpyp+l++++ fy ++k+Gyrma+pa+a++e+yeim+kcw++++ekrp f+ lv

Q: 888   LGGTPYPDLPMNEIFYSALKRGYRMAKPAHASDEVYEIMKKCWDEKFEKRPEFSLLV  944

         *****************************************************9887

Domain Sequence
(FASTA)

LVLGRTLGSG AFGRVVEATA YGLTQSHSST KVAVKMLKST ARRSETQALM SELKIMSHLG 60

PHLNIVNLLG ACTKHGPLYL VTEYCRYGDL VDYLHRNKHT FLQYYAEKNQ DSGCIISRGS 120

TPLSQRKGYV SFGSESDGGY MDMSKDEPSF YVPMQEQLDT IKYADIQPSP YESPYQQDLY 180

QEQGGGRLDL VIGDSPTLTY DDLLGFSYQV AKGMDFLASK NCVHRDLAAR NVLICEGKLV 240

KICDFGLARD IMHDSNYISK GSTFLPLKWM APESIFHNLY TTLSDVWSYG ILLWEIFTLG 300

GTPYPDLPMN EIFYSALKRG YRMAKPAHAS DEVYEIMKKC WDEKFEKRPE FSLLV 355

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>