EKS-XIM-00072

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XIM-00072

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/RAF	372.4	1.5E-111	459	698	240

Status

Unreviewed

Ensembl Protein

ENSXMAP00000008591

Gene Name

BRAF

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXMAG00000008567	ENSXMAP00000008591	ENSXMAT00000008604

Organism

Xiphophorus maculatus

Protein Length

751

Protein Sequence
(FASTA)

QIWNIKQMIK LTQEHLEALL EKFGGEHNPP SIYLEAYEEY TSKLDALQQR EQQLLEAMGN 60

ATDLSCTTSP MSSDAVGGGA QALPSAPNSL AVLQTPTDTG RSNPRSPQKP IVRVFLPNKQ 120

RTVVPARCGM TVRDSLKKAL MMRGLIPECC AVYRIQDGEK KPIGWDTDIS WLTGEELHVE 180

VLENVPLTTH NFVRKTFFTL AFCDFCRKLL FQGFRCQTCG YKFHQRCSTE VPLMCVNYDQ 240

LDLLLVSKFF EHHPFSQEEV SSEGTTPVSE LCPSLPPSDS TGSIYHTTVS PSKSIPIPNS 300

FRTSEEDHRN QFGQRDRSSS APNVHINTIE PVNIDVSLLD KLNMINYVQF SQGNEYCLII 360

YLLLYVFIWR RTNKEGFINK ISLLVSHPPE FLYGDLTKLI CMDVSQDPVE YQNLLTNPPR 420

NITDRLQNKP YFSYWQIGAL DFFVVVYGQY SLSFLTGKWW HSDVAVKMLN VTAPTPQQLQ 480

AFKNEVGVLR KTRHVNILLF MGYTTKPQLA IVTQWCEGSS LYHHLHIIET KFEMIKLIDI 540

ARQTAQGMDY LHAKSIIHRD LKSNNIFLHE DLTVKIGDFG LATVKSRWSG SHQFEQLSGS 600

ILWMAPEVIR LQDKNPYSFQ SDVYAFGIVL YELMSGALPY SNINNRDQII FMVGRGYLSP 660

DLSKVRSNCP KAMKRLMADC LKKKREERPL FPQILASIEL LARSLPKIHR SASEPSLNRA 720

GFQTEDFSLY SCASPKTPIQ AGGYGEFSAF K 751

Nucleotide Sequence
(FASTA)

CAGATCTGGA ACATCAAGCA GATGATAAAG CTGACACAGG AACACTTAGA GGCTCTGCTG 60

GAGAAATTTG GAGGCGAACA CAATCCTCCT TCCATATATT TGGAGGCATA TGAAGAGTAC 120

ACCAGTAAAC TGGACGCCCT GCAGCAGAGA GAGCAGCAGC TACTGGAAGC CATGGGGAAT 180

GCCACAGACC TCTCCTGCAC CACTTCCCCT ATGTCAAGTG ATGCAGTTGG AGGTGGAGCT 240

CAGGCTCTTC CCTCAGCCCC CAACTCATTA GCAGTCCTGC AGACCCCCAC CGATACTGGA 300

CGGTCCAATC CACGCTCCCC CCAGAAGCCT ATTGTCCGTG TGTTCTTGCC AAACAAACAG 360

AGAACAGTGG TCCCAGCCCG CTGTGGGATG ACTGTGAGGG ACTCACTGAA GAAAGCTCTG 420

ATGATGCGGG GACTCATCCC AGAGTGCTGT GCAGTCTATA GAATACAGGA TGGAGAAAAG 480

AAGCCTATTG GCTGGGACAC AGACATCTCC TGGCTGACTG GAGAGGAGCT CCACGTGGAA 540

GTGTTGGAGA ATGTGCCACT TACCACACAT AACTTTGTGA GGAAGACCTT CTTCACATTG 600

GCCTTCTGTG ATTTCTGTAG AAAACTGCTG TTCCAGGGTT TTCGCTGTCA GACCTGTGGC 660

TACAAGTTCC ATCAGCGCTG CAGCACAGAG GTTCCTCTCA TGTGTGTCAA CTATGACCAG 720

CTAGACTTGC TGCTTGTATC AAAGTTCTTC GAGCATCATC CGTTCAGCCA GGAAGAGGTC 780

TCCTCAGAGG GAACCACACC TGTGTCTGAG CTCTGTCCAT CTCTCCCCCC ATCGGACTCT 840

ACCGGCTCTA TATACCACAC TACAGTGTCC CCATCCAAGT CCATTCCCAT TCCAAATAGT 900

TTTCGGACCA GTGAGGAAGA CCACCGCAAC CAGTTTGGCC AGCGAGATCG TTCGTCCTCC 960

GCCCCCAATG TCCATATTAA CACCATTGAG CCTGTCAACA TTGATGTGAG TCTGCTGGAC 1020

AAGCTGAATA TGATAAACTA TGTTCAATTT TCACAAGGTA ATGAGTACTG TTTAATTATT 1080

TATTTGTTAT TGTATGTATT TATCTGGAGG CGCACAAACA AGGAAGGCTT CATTAATAAA 1140

ATCTCCCTGT TGGTCTCGCA CCCACCAGAA TTTCTTTATG GAGATTTGAC TAAACTTATA 1200

TGCATGGATG TTTCTCAAGA TCCTGTTGAA TATCAAAATC TACTGACGAA TCCTCCAAGA 1260

AATATCACTG ACAGATTACA AAATAAACCA TATTTTAGTT ACTGGCAGAT TGGAGCTTTG 1320

GATTTTTTTG TTGTTGTTTA TGGACAATAT TCGCTTTCAT TTTTAACTGG AAAGTGGTGG 1380

CACAGTGATG TGGCTGTGAA AATGCTGAAT GTCACTGCTC CCACTCCACA GCAGCTTCAG 1440

GCCTTCAAGA ATGAAGTGGG CGTCCTCAGA AAAACGCGTC ATGTGAATAT CTTGCTGTTC 1500

ATGGGTTACA CAACCAAACC CCAGCTGGCC ATTGTGACCC AGTGGTGTGA AGGCTCCAGT 1560

CTGTACCACC ATCTGCACAT CATTGAAACC AAATTTGAGA TGATCAAGCT GATCGACATC 1620

GCCCGTCAGA CTGCTCAGGG CATGGATTAC CTACATGCCA AGTCCATTAT TCACAGAGAC 1680

CTGAAGAGCA ACAATATTTT CCTGCATGAG GATCTGACCG TGAAGATTGG TGACTTTGGT 1740

CTAGCCACAG TCAAATCTCG TTGGAGCGGC TCCCACCAGT TCGAGCAACT GTCTGGTTCA 1800

ATACTTTGGA TGGCTCCAGA GGTGATCAGG TTGCAGGACA AGAATCCCTA CAGCTTCCAG 1860

TCAGATGTGT ATGCTTTCGG CATTGTGCTC TATGAGCTCA TGTCAGGAGC TCTGCCCTAT 1920

TCCAACATTA ACAACAGAGA CCAGATTATC TTCATGGTGG GTCGAGGTTA CCTTTCTCCA 1980

GACCTGAGCA AGGTCCGCAG CAACTGTCCT AAGGCCATGA AAAGACTGAT GGCAGATTGC 2040

TTGAAGAAAA AGAGAGAAGA GCGACCCCTC TTCCCCCAGA TTTTGGCATC CATTGAACTG 2100

CTGGCTCGTT CATTACCCAA AATCCACCGC AGCGCCTCTG AACCTTCCTT AAATCGAGCA 2160

GGCTTTCAGA CGGAAGACTT TAGCCTGTAC TCCTGCGCCT CACCTAAAAC TCCCATTCAA 2220

GCTGGAGGTT ATGGGGAGTT TTCTGCATTC AAGTAA 2256

Domain Profile

S: 19    kwhGdvavkllnveelseeqleaFkkevaaykktRhenivLFmGyvskpelaivtslckg  78

          wh dvavk+lnv++++++ql+aFk+ev +++ktRh+ni+LFmGy +kp+laivt++c+g

Q: 459   WWHSDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYTTKPQLAIVTQWCEG  518

         48**********************************************************

S: 79    ssLykllheqetkldlaklidiarqiaqgmdYLhakkilhkDlksknilleeglkvvitD  138

         ssLy++lh  etk+++ klidiarq+aqgmdYLhak+i+h+Dlks+ni+l+e+l+v+i+D

Q: 519   SSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGD  578

         ************************************************************

S: 139   FgllsvkrllsgrrekqleipkgwilylapeviralsidleqdelpfskesDvyafGivl  198

         Fgl++vk+++sg  ++q+e+ +g+il++apevir       qd++p+s++sDvyafGivl

Q: 579   FGLATVKSRWSG--SHQFEQLSGSILWMAPEVIRL------QDKNPYSFQSDVYAFGIVL  630

         ************..*********************......*******************

S: 199   yellarelpyke.esadqilfavgrG.lkpdlskvksklpkelkellleClkfekeeRPl  256

         yel++++lpy++ +++dqi+f+vgrG l+pdlskv+s++pk++k+l+++Clk+++eeRPl

Q: 631   YELMSGALPYSNiNNRDQIIFMVGRGyLSPDLSKVRSNCPKAMKRLMADCLKKKREERPL  690

         ************************************************************

S: 257   ftqilkkl  264

         f+qil+++

Q: 691   FPQILASI  698

         ****9875

Domain Sequence
(FASTA)

WWHSDVAVKM LNVTAPTPQQ LQAFKNEVGV LRKTRHVNIL LFMGYTTKPQ LAIVTQWCEG 60

SSLYHHLHII ETKFEMIKLI DIARQTAQGM DYLHAKSIIH RDLKSNNIFL HEDLTVKIGD 120

FGLATVKSRW SGSHQFEQLS GSILWMAPEV IRLQDKNPYS FQSDVYAFGI VLYELMSGAL 180

PYSNINNRDQ IIFMVGRGYL SPDLSKVRSN CPKAMKRLMA DCLKKKREER PLFPQILASI 240

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>