EKS-XIM-00267

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XIM-00267

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF2	456.2	6.3E-137	143	497	355

Status

Unreviewed

Ensembl Protein

ENSXMAP00000012403

Gene Name

PINK1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXMAG00000012373	ENSXMAP00000012403	ENSXMAT00000012419

Organism

Xiphophorus maculatus

Protein Length

575

Protein Sequence
(FASTA)

MSVKHAISRG LELGRSFLQI GLLKSGGRVA AKLRADRFRV GPSVRTVQPQ AFLPARYRYY 60

RTSLRGLAAQ LQSAGFRRRF TGASPRNRAV FLAFGLGVGL IEQQLEEDRQ SAATCQEIQA 120

VFKKKKIQST LRPFTSGFKL EDYIIGNQIG KGSNAVVYEA AAQFAHPKET ERDSTLVELR 180

DIKEEVQTAR SPTCCSFRNF PLAIKMLWNF GAGSSSEAIL KSMSQELVPS GPLALKQEKE 240

QVTLDGHFGV LPRRVSAHPN VIRVYRAFTA DVPLLPGAQE EYPDVLPARL NPTGIGNNRT 300

LFLVMKNYPY TLRQYLLVST PNRRQGSLMV LQLLEGVDHL CRQGVAHRDL KSDNILLEFD 360

SGGCPRLVIT DFGCCLTQND SSLQLPFNNM WVSRGGNASL MAPEVVTAAP GPDVVIDYTK 420

TDAWAVGAIS YEIFGQQNPF YGAAGLHSTN YQEKQLPPLP ACVPADVQLV AKLLLRRNPN 480

KRPSARVAAN MLHLSLWGRK ALANQDSAGM RKLADWLLCQ SAVVLLQGCS GPSGNRVEAE 540

LQRSFLSNLD LEELRAAVGF LLYGQDQSRA CIMFP 575

Nucleotide Sequence
(FASTA)

ATGTCTGTGA AACACGCCAT TAGCCGAGGG CTGGAGCTCG GCCGGTCCTT TCTTCAGATT 60

GGTCTCCTTA AATCAGGCGG CCGAGTCGCA GCAAAGCTCC GAGCTGACCG TTTCCGTGTA 120

GGCCCGTCGG TCCGCACCGT TCAGCCTCAG GCTTTCCTGC CGGCCCGGTA CCGCTATTAC 180

CGCACCTCTC TGAGGGGTCT GGCGGCTCAG CTTCAGTCCG CCGGTTTTAG AAGGAGGTTT 240

ACCGGCGCGT CGCCTCGGAA CAGGGCCGTG TTTCTGGCTT TTGGCCTCGG TGTGGGGCTT 300

ATCGAGCAGC AGCTGGAGGA GGACAGACAG AGCGCTGCAA CATGTCAAGA AATACAGGCT 360

GTGTTTAAGA AGAAAAAAAT CCAGAGCACA CTGAGACCTT TCACCTCTGG ATTCAAACTA 420

GAGGACTACA TTATAGGGAA CCAGATCGGT AAAGGTTCCA ATGCGGTTGT GTACGAGGCT 480

GCAGCTCAGT TTGCTCACCC TAAGGAGACG GAGAGAGACT CGACGTTGGT GGAACTACGG 540

GACATTAAAG AGGAAGTCCA GACAGCGCGA TCTCCAACAT GCTGCTCCTT CAGAAACTTC 600

CCTTTGGCTA TCAAAATGTT GTGGAACTTT GGGGCTGGAT CTTCAAGTGA GGCGATATTA 660

AAATCTATGT CACAAGAACT TGTCCCATCT GGTCCTCTGG CCTTAAAACA GGAAAAAGAG 720

CAGGTTACCC TGGATGGACA TTTTGGAGTG CTTCCCAGAA GAGTTTCAGC TCACCCAAAC 780

GTGATCAGAG TGTATCGGGC TTTCACCGCA GACGTGCCGC TGCTACCAGG TGCACAGGAG 840

GAGTATCCAG ATGTGCTGCC AGCTAGGCTC AACCCCACGG GCATCGGAAA CAATCGCACT 900

CTTTTCCTAG TCATGAAAAA CTATCCCTAC ACACTGCGGC AGTACCTGCT GGTTTCCACA 960

CCCAACCGCA GGCAGGGCTC TCTGATGGTG CTGCAGCTCC TGGAGGGGGT GGACCATCTG 1020

TGCAGGCAGG GTGTTGCTCA CAGGGATCTG AAGTCAGACA ACATACTGCT AGAGTTTGAC 1080

TCAGGTGGCT GCCCCCGTTT AGTAATTACT GACTTCGGCT GCTGCCTGAC CCAGAATGAC 1140

TCCAGCTTAC AGCTTCCATT TAACAACATG TGGGTCAGCA GAGGAGGAAA CGCTTCACTC 1200

ATGGCTCCTG AGGTGGTGAC TGCAGCTCCA GGTCCTGATG TGGTGATCGA CTACACCAAG 1260

ACGGATGCCT GGGCTGTGGG GGCAATCTCC TATGAGATAT TTGGACAGCA GAATCCTTTC 1320

TATGGAGCTG CAGGATTGCA CAGCACAAAT TACCAGGAGA AGCAGCTACC TCCTCTTCCT 1380

GCCTGTGTTC CAGCTGATGT TCAGTTAGTT GCTAAACTGC TACTCAGGAG GAACCCAAAC 1440

AAGCGCCCCA GTGCTCGTGT TGCAGCTAAC ATGCTGCATC TCAGCCTCTG GGGTCGTAAA 1500

GCCCTAGCCA ATCAGGACAG CGCTGGCATG AGAAAGCTGG CTGATTGGCT GCTGTGCCAG 1560

TCGGCTGTGG TTCTCCTGCA GGGCTGCAGC GGCCCCAGTG GAAACAGAGT GGAGGCGGAG 1620

CTTCAGAGGA GCTTTCTGTC TAACCTTGAT CTAGAAGAGC TGCGTGCCGC TGTAGGCTTC 1680

CTCCTTTATG GGCAAGATCA GAGCAGGGCC TGCATTATGT TTCCATAA 1728

Domain Profile

S: 1     yligealgkgcnaavyeatlatldqelekakhlgllgkevtvvlaeidqesavaakkfpl  60

         y ig+ +gkg na vyea    ++ +  +  ++ +  ++++  ++ + +    + ++fpl

Q: 143   YIIGNQIGKGSNAVVYEAAAQFAHPKETERDSTLVELRDIKEEVQTARSPTCCSFRNFPL  202

         89***************98776655555556666678999999999999999999*****

S: 61    aiklmfnieadssseallksmsqelvpasrva.........ldgeygavpkllakhPniv  111

         aik+++n+ a+sssea+lksmsqelvp    a         ldg++g +p++++ hPn++

Q: 203   AIKMLWNFGAGSSSEAILKSMSQELVPSGPLAlkqekeqvtLDGHFGVLPRRVSAHPNVI  262

         ***************************8655544444444489999999***********

S: 112   rvlrafidsvkllPdalldyPdalparlypeglgegktlylvmkrydqtlreylesqdrs  171

         rv+raf+ +v+llP+a ++yPd+lparl+p g+g+++tl+lvmk+y+ tlr+yl + +++

Q: 263   RVYRAFTADVPLLPGAQEEYPDVLPARLNPTGIGNNRTLFLVMKNYPYTLRQYLLVSTPN  322

         ************************************************************

S: 172   trlaalllaqlleavdhlvkhgvahrdlksdnilveldddeiPvlviadfGCcladkvdg  231

          r++ l+++qlle+vdhl ++gvahrdlksdnil+e+d+ ++P lvi+dfGCcl ++  +

Q: 323   RRQGSLMVLQLLEGVDHLCRQGVAHRDLKSDNILLEFDSGGCPRLVITDFGCCLTQNDSS  382

         ************************************************************

S: 232   lrlpyessevdkGGnaalmaPeistavpGpsavinyekadtWavGalayeifglsnPfyg  291

         l+lp++   v++GGna+lmaPe++ta pGp +vi+y k d+WavGa++yeifg++nPfy

Q: 383   LQLPFNNMWVSRGGNASLMAPEVVTAAPGPDVVIDYTKTDAWAVGAISYEIFGQQNPFY-  441

         ***********************************************************.

S: 292   egkaslesasyqeaqlPalpesvppelrqlvydllkreaskrvsadiaanvlqlslf  348

          g+a l+s++yqe+qlP+lp  vp +++ +   ll+r+++kr+sa++aan+l+lsl+

Q: 442   -GAAGLHSTNYQEKQLPPLPACVPADVQLVAKLLLRRNPNKRPSARVAANMLHLSLW  497

         .678999*********************99999***********************9

Domain Sequence
(FASTA)

YIIGNQIGKG SNAVVYEAAA QFAHPKETER DSTLVELRDI KEEVQTARSP TCCSFRNFPL 60

AIKMLWNFGA GSSSEAILKS MSQELVPSGP LALKQEKEQV TLDGHFGVLP RRVSAHPNVI 120

RVYRAFTADV PLLPGAQEEY PDVLPARLNP TGIGNNRTLF LVMKNYPYTL RQYLLVSTPN 180

RRQGSLMVLQ LLEGVDHLCR QGVAHRDLKS DNILLEFDSG GCPRLVITDF GCCLTQNDSS 240

LQLPFNNMWV SRGGNASLMA PEVVTAAPGP DVVIDYTKTD AWAVGAISYE IFGQQNPFYG 300

AAGLHSTNYQ EKQLPPLPAC VPADVQLVAK LLLRRNPNKR PSARVAANML HLSLW 355

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>