EKS-CAE-00100

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAE-00100

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Met	421.5	1.8E-126	75	335	261

Status

Unreviewed

Ensembl Protein

F11E6.8b

UniProt Accession

Q9XVQ7;

Protein Name

Protein Synonyms/Alias

Protein F11E6.8, isoform a;

Gene Name

F11E6.8

Gene Synonyms/Alias

F11E6.8;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
F11E6.8	F11E6.8c	F11E6.8c
F11E6.8	F11E6.8b	F11E6.8b
F11E6.8	F11E6.8a	F11E6.8a

Organism

Caenorhabditis elegans

Functional Description

Protein Length

380

Protein Sequence
(FASTA)

MNPVFLDTSD SDSEQSSSSR YRSPSHPSSL PRSSSRQQSS TSVSSTYSTQ SLLQLIGSDL 60

RQSLQGLLLP SEAVVLETIV GKGYFGNVYR GRMRDPAGRL IPVAVKTLKG ERARDIAHIE 120

KFLREGVVMK HLDHPHVLSL LGISISPAGN PWVVLPYMEG GDLKTYIADP NRALCVLELL 180

DFAHQVAQGM SYLAAQHFVH RDLAARNCMI SADRIVKVAD FGLAVDLLDK ESYIDESETG 240

PARLPLKWLA PESLRDRRVF SSATDVWSFG VLMWELLTRA ASPYGEVSNT KVRHYLETGM 300

RLPQPTHCPD IIYDLMQCCW RSTPEDRPDF VFLSHRLRAL LQENTPDPFT RRVRPGAEQF 360

LLPVLPGRLF TNYFAAQMHS 380

Nucleotide Sequence
(FASTA)

ATGAATCCCG TGTTTCTGGA CACTTCCGAT TCTGACTCTG AACAGAGCTC TTCAAGTCGG 60

TATCGATCAC CATCTCACCC TTCGAGTCTA CCCAGATCTT CATCACGACA ACAATCTTCC 120

ACTAGCGTAT CCTCTACATA CTCAACACAA AGTCTTTTGC AATTAATTGG CTCCGATCTC 180

CGTCAATCCC TTCAAGGACT CTTGTTGCCT TCGGAAGCAG TCGTTTTGGA GACTATTGTT 240

GGAAAAGGGT ACTTTGGAAA TGTGTACAGA GGACGAATGC GGGATCCAGC AGGACGACTC 300

ATACCGGTTG CGGTCAAAAC ACTGAAAGGT GAACGTGCTC GAGATATTGC CCATATTGAA 360

AAATTTTTGC GGGAAGGCGT AGTGATGAAA CACCTAGATC ATCCTCATGT TTTATCGCTT 420

CTCGGAATAT CAATATCACC AGCTGGCAAT CCATGGGTTG TACTACCATA CATGGAGGGA 480

GGCGATCTAA AGACGTATAT TGCAGATCCA AATAGGGCAT TGTGCGTTCT TGAGCTCCTT 540

GACTTTGCTC ATCAAGTGGC TCAAGGCATG AGTTATTTGG CAGCTCAACA CTTCGTTCAT 600

CGTGACTTGG CCGCTCGTAA CTGTATGATA TCAGCTGATC GAATTGTGAA AGTCGCAGAC 660

TTTGGTTTGG CTGTTGATTT ATTGGATAAA GAAAGTTATA TTGATGAGAG TGAAACAGGA 720

CCAGCCCGTC TTCCATTAAA ATGGCTAGCA CCAGAGAGTC TTCGTGATAG AAGAGTTTTC 780

AGTTCAGCTA CTGATGTGTG GTCATTTGGA GTATTAATGT GGGAATTGTT GACACGAGCT 840

GCTTCTCCAT ATGGTGAAGT ATCAAATACA AAAGTGAGAC ACTACTTGGA AACTGGAATG 900

CGACTCCCAC AACCAACGCA TTGCCCGGAT ATTATTTATG ATTTGATGCA ATGTTGTTGG 960

CGCTCAACTC CAGAAGACAG GCCTGATTTC GTCTTTCTAT CACATCGATT GAGAGCATTA 1020

CTGCAGGAAA ATACTCCAGA TCCTTTCACT CGCAGAGTTC GTCCGGGGGC TGAACAATTT 1080

TTACTCCCAG TTCTTCCAGG CCGTCTTTTC ACTAATTATT TTGCTGCTCA GATGCATTCT 1140

TAA 1143

Domain Profile

S: 2     dkeeviGkGhfGvvykgelsdsaskkikvavksl..eritdiekveeflreglvmkeldh  59

           e+++GkG+fG+vy+g+++d+a++ i vavk+l  er++di+++e+flreg+vmk+ldh

Q: 75    VLETIVGKGYFGNVYRGRMRDPAGRLIPVAVKTLkgERARDIAHIEKFLREGVVMKHLDH  134

         6789******************************999***********************

S: 60    pnvlsllGialddeglplvvlpymkkGdlksfirneernltvkdllefalqvakgmeyla  119

         p+vlsllGi+++++g+p+vvlpym+ Gdlk++i++++r+l+v +ll+fa+qva+gm+yla

Q: 135   PHVLSLLGISISPAGNPWVVLPYMEGGDLKTYIADPNRALCVLELLDFAHQVAQGMSYLA  194

         ************************************************************

S: 120   skkfvhrdlaarnclldekltvkvadfGlardvldkelyvveeerd.arlpvkwlalesl  178

         +++fvhrdlaarnc+++++++vkvadfGla+d+ldke+y++e+e++ arlp+kwla+esl

Q: 195   AQHFVHRDLAARNCMISADRIVKVADFGLAVDLLDKESYIDESETGpARLPLKWLAPESL  254

         *********************************************99*************

S: 179   qtfkqfttksdvwsfGvllwelltrgatpysevasfdltlylkegrrlrkpeycpdklyd  238

         +++++f++++dvwsfGvl+welltr+a+py+ev+++++++yl++g+rl++p++cpd++yd

Q: 255   RDRRVFSSATDVWSFGVLMWELLTRAASPYGEVSNTKVRHYLETGMRLPQPTHCPDIIYD  314

         ************************************************************

S: 239   vmlkcwkakpaerpqfsdlvs  259

         +m++cw+++p++rp+f+ l

Q: 315   LMQCCWRSTPEDRPDFVFLSH  335

         ****************86655

Domain Sequence
(FASTA)

VLETIVGKGY FGNVYRGRMR DPAGRLIPVA VKTLKGERAR DIAHIEKFLR EGVVMKHLDH 60

PHVLSLLGIS ISPAGNPWVV LPYMEGGDLK TYIADPNRAL CVLELLDFAH QVAQGMSYLA 120

AQHFVHRDLA ARNCMISADR IVKVADFGLA VDLLDKESYI DESETGPARL PLKWLAPESL 180

RDRRVFSSAT DVWSFGVLMW ELLTRAASPY GEVSNTKVRH YLETGMRLPQ PTHCPDIIYD 240

LMQCCWRSTP EDRPDFVFLS H 261

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase; Tyrosine-protein kinase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity

KEGG

cel:CELE_F11E6.8

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.

Pfam

PF07714

; Pkinase_Tyr; 1.

SMARTs

SM00219

; TyrKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.

Prints

PR00109

; TYRKINASE.

Created Date

20-Feb-2013