EPS-CAE-00017

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CAE-00017

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	48.6	1.4E-12	693	882	190

Status

Reviewed

Ensembl Protein

F43C1.1

UniProt Accession

Q09564;

Protein Name

Protein phosphatase PHLPP-like protein

Protein Synonyms/Alias

Gene Name

F43C1.1

Gene Synonyms/Alias

F43C1.1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
F43C1.1	F43C1.1	F43C1.1

Organism

Caenorhabditis elegans

Functional Description

Probable protein phosphatase (By similarity).

Protein Length

1036

Protein Sequence
(FASTA)

MSDENLETES TSKALEDILS YTDSPAFRHI FSFFLGRPRI RAKSTLNLDI LSEEVVIRKG 60

KLIHTWQNAR AVFYNSNIRL QTKNNQDEAL QIRNMKVDVH ESKRGRALRL KDDDVCYLII 120

FQRPNILEAW LTRAQQVEKS NHVDASDEQL TLIPEQILNN EARVQILNLR RNSLISRPPT 180

EKSMAPLGYI DDLYRVHSLQ VIDLSANQIL SFPIQLTLLS HLRQLNLSSN YISSVPSECS 240

NMRRLQYLNL SNNQLDTLPD SISELQNLQS LDISFNQFSQ IPPCLFHLTL EMWRLAGNNI 300

EKIDRVGEMQ IQKIDLRRNV LDTSFRLDIE NITHLDLRDN SMISTVHLTN LRFLKVIHCE 360

RLQLSSLHLS GESLTHVYAD HNLLDSLVVM PLPQNLQTLS LSFNHFRNLP DWISDCPNLT 420

FLRANNNSLV ALPERIFYSQ SLRSIFAFIN EIEHIPDFGE ENCLETLILY KNKLSSLPKH 480

FFSILPRLRQ LNISSNFIEL LPYFDGSSFC RLQILRCANN YLTENSVPVI VNMKHLKIID 540

LSHNRLNSFD DSALSSLELL EDLNLSSNRL TRLADCLALL PCLQVLRAHS NQLVHVPEFR 600

ASNQLHTIDV SSNNISLGTL QFKAPPNLRH FDVTCNSGDF DTENFPENAK MHSKMNTINI 660

SEGSQNLFGF QIGVSGSRGM KNKQCIRQVR VENTFGFIDG GSNSYMSSSI CRFMTSYLKE 720

NVSMDIRSIL LRCHCELGEE GERLGASVMI IRVHEKRLEI ASTGTMSAAI ARNQKLKMII 780

NGRYEIDDDE YSRIREAHGF VDEENRINGV IGSSRQIGHF STFPVVLPTH SYRNIQLNEQ 840

IEGLIVGNNM IWNMLSIDDL NSTFHNNRSP IVVAKKIQDQ LQSYDYGGNS NILVLRRIKP 900

QMTFNGFSTS STKNQVTPDI AIPKIDEQLV LAVPALILPE YHPSPPVPPP IPAIRHRTPS 960

PPPPPLPSST PPPVSSEHEE INVRQSSTLS GGYTLSIDRF YSSSSTVSSR KQFNETRDLL 1020

SKSLKLSPPN TVTFNI 1036

Nucleotide Sequence
(FASTA)

ATGTCCGATG AGAATCTGGA GACTGAAAGC ACATCGAAAG CCTTGGAAGA TATTTTATCA 60

TACACTGATT CGCCGGCATT CCGCCATATT TTTAGCTTTT TTCTGGGCCG GCCAAGAATT 120

CGTGCGAAGA GTACATTGAA TTTGGATATT CTAAGTGAAG AAGTTGTGAT ACGAAAAGGA 180

AAGCTAATTC ACACGTGGCA AAATGCGCGA GCCGTATTTT ACAATTCAAA TATTCGATTG 240

CAAACCAAAA ACAACCAAGA TGAGGCTCTT CAAATTCGAA ATATGAAAGT AGATGTACAT 300

GAGTCCAAAA GAGGAAGAGC TCTTCGACTA AAAGATGATG ATGTGTGTTA TCTTATAATC 360

TTTCAAAGAC CGAATATTCT AGAAGCATGG CTTACACGGG CTCAACAAGT GGAGAAGAGT 420

AACCACGTGG ATGCAAGTGA CGAGCAATTG ACATTAATAC CTGAACAGAT TTTGAATAAT 480

GAAGCGAGAG TTCAAATTTT GAATTTAAGA AGAAACTCGC TGATTTCTAG GCCACCAACT 540

GAAAAGTCAA TGGCTCCACT TGGCTACATA GATGACCTAT ACCGTGTCCA TTCTCTACAA 600

GTAATCGATT TATCTGCCAA TCAAATTCTC TCATTTCCAA TTCAATTAAC ACTTTTATCA 660

CATCTCCGAC AACTTAATCT ATCATCTAAC TACATATCAT CAGTCCCAAG TGAATGCTCA 720

AATATGCGAC GTTTACAATA TTTAAACTTA TCGAATAATC AATTAGACAC TCTACCAGAT 780

TCAATTAGTG AACTTCAAAA CTTGCAGAGT TTGGATATTA GTTTCAATCA ATTCTCACAG 840

ATTCCACCCT GCCTTTTCCA CCTTACTCTC GAAATGTGGA GGCTTGCTGG AAACAATATA 900

GAGAAGATCG ATAGAGTCGG AGAAATGCAA ATTCAAAAAA TCGATCTTCG AAGAAACGTG 960

CTTGACACCT CATTTCGACT TGATATCGAA AATATAACAC ATTTGGATTT GAGAGATAAT 1020

TCTATGATTT CTACAGTTCA TCTCACGAAT TTGAGGTTTT TGAAAGTAAT TCATTGCGAA 1080

CGTCTCCAAT TGTCAAGTCT ACATTTGAGT GGAGAAAGTT TGACTCATGT ATATGCAGAT 1140

CATAATTTAC TTGATTCCCT GGTCGTGATG CCTCTTCCAC AAAACCTACA AACTCTTTCA 1200

CTTTCTTTCA ATCACTTTCG AAATCTGCCA GATTGGATAT CAGATTGCCC GAATTTGACA 1260

TTTCTCCGAG CAAATAATAA TAGCCTTGTG GCACTGCCAG AGAGAATATT CTACTCCCAA 1320

TCTCTTCGTT CAATATTTGC ATTTATCAAT GAAATCGAAC ATATTCCGGA TTTTGGAGAA 1380

GAAAATTGTC TAGAAACATT AATACTTTAT AAGAATAAAC TGTCCTCACT TCCCAAACAT 1440

TTCTTCAGTA TATTGCCAAG ATTACGACAG CTCAATATTT CATCGAATTT TATAGAATTA 1500

TTGCCATATT TTGATGGTTC ATCGTTTTGC AGACTACAAA TCCTACGTTG CGCCAACAAC 1560

TATTTAACAG AGAACAGTGT GCCAGTGATT GTAAATATGA AACATTTAAA AATAATTGAT 1620

CTCAGTCATA ATCGATTAAA TTCTTTCGAT GACAGTGCTC TCAGCTCTTT GGAGCTTCTG 1680

GAAGATCTCA ATTTAAGTTC AAACCGCCTG ACAAGACTTG CTGATTGTTT GGCTCTTTTG 1740

CCATGTTTAC AAGTGCTCAG AGCTCATTCA AATCAACTTG TTCATGTTCC AGAATTTCGA 1800

GCATCTAATC AGTTACATAC AATAGATGTC TCATCGAATA ACATCTCACT TGGAACTCTC 1860

CAATTCAAAG CTCCGCCAAA TTTACGCCAT TTCGATGTGA CGTGTAACTC TGGAGATTTC 1920

GATACGGAAA ACTTCCCGGA AAACGCAAAA ATGCATTCAA AAATGAATAC GATAAATATT 1980

TCCGAAGGGT CACAAAATCT CTTTGGCTTT CAAATTGGAG TCTCAGGCAG TCGAGGAATG 2040

AAAAATAAAC AATGTATCCG ACAAGTTCGA GTTGAAAACA CATTTGGATT TATCGATGGA 2100

GGATCCAATT CCTATATGTC ATCGTCGATT TGCAGGTTCA TGACTAGTTA TTTGAAAGAG 2160

AATGTATCGA TGGATATTCG ATCGATACTC TTGAGATGTC ATTGTGAACT TGGAGAAGAG 2220

GGAGAACGAT TGGGAGCTAG TGTAATGATA ATTCGTGTTC ACGAAAAACG ACTGGAGATT 2280

GCGTCAACTG GAACAATGAG TGCAGCGATT GCAAGAAACC AGAAATTGAA AATGATAATA 2340

AATGGACGGT ATGAAATCGA TGATGACGAA TATTCTCGAA TACGTGAAGC CCATGGATTC 2400

GTTGATGAAG AAAATCGAAT AAATGGAGTA ATTGGATCAT CCCGTCAAAT TGGACATTTT 2460

TCTACTTTTC CTGTTGTTTT ACCAACTCAT TCCTATCGAA ATATTCAATT AAATGAACAA 2520

ATTGAGGGAT TAATAGTTGG AAATAATATG ATATGGAATA TGTTATCAAT TGATGACCTT 2580

AATTCCACTT TTCATAATAA TCGTAGTCCT ATTGTGGTGG CGAAGAAGAT TCAGGACCAA 2640

CTACAATCAT ATGATTATGG CGGGAATTCG AATATTCTCG TTCTACGACG AATAAAACCA 2700

CAAATGACAT TTAATGGATT TTCAACATCT TCTACAAAAA ACCAAGTGAC TCCGGATATT 2760

GCGATACCCA AAATTGACGA ACAATTAGTG CTAGCTGTTC CTGCCCTAAT ACTTCCGGAA 2820

TATCATCCAT CTCCTCCAGT TCCACCACCA ATTCCAGCAA TTCGTCATCG TACTCCATCT 2880

CCACCACCAC CACCACTTCC ATCATCAACA CCTCCACCAG TTTCTTCAGA ACATGAAGAG 2940

ATTAATGTTC GTCAGAGTTC AACACTTTCT GGAGGATATA CGTTATCGAT TGATAGATTT 3000

TACAGTAGTA GTAGTACTGT ATCCTCGAGA AAACAGTTCA ATGAGACACG AGATTTGTTG 3060

AGCAAGTCAC TGAAATTGAG CCCTCCTAAT ACGGTTACTT TTAATATTTA A 3111

Domain Profile

S: 36    affgvyDGhggsevakfcseklheilaeelesseseerkvkkalakaFlstdeelkvlee  95

           fg  DG  +s +++ +   ++++l+e+++            +++ +l+++ el

Q: 693   NTFGFIDGGSNSYMSSSICRFMTSYLKENVS----------MDIRSILLRCHCEL-----  737

         4688888777777777777777777777755..........55999999999999.....

S: 96    ksldidksGstavvalikdsklyvanvGdSravLcrngk.avelssdHkpsredEleRie  154

           ++ ++ G++++++ + ++ l +a +G   a ++rn+k  + +   ++++  dE++Ri+

Q: 738   -GEEGERLGASVMIIRVHEKRLEIASTGTMSAAIARNQKlKMIINGRYEIDD-DEYSRIR  795

         .8899*******************************8864677788888887.*******

S: 155   eaggsvilkdgaRvlGvLavsRalGdlylkpyvtpePevtshrltsedefliLasDGlwd  214

         ea+g v +++  R++Gv+  sR +G +   p+v p+     ++l+++ e li +   +w+

Q: 796   EAHGFVDEEN--RINGVIGSSRQIGHFSTFPVVLPTHSYRNIQLNEQIEGLIVGNNMIWN  853

         *********9..************************************************

S: 215   vvsneeavslvrdvlekkeaeqeaakkLvklal  247

         ++s  ++ s  ++  +    +  +akk+ ++++

Q: 854   MLSIDDLNSTFHNNRS----PIVVAKKIQDQLQ  882

         ***9988776654444....5555555555555

Domain Sequence
(FASTA)

NTFGFIDGGS NSYMSSSICR FMTSYLKENV SMDIRSILLR CHCELGEEGE RLGASVMIIR 60

VHEKRLEIAS TGTMSAAIAR NQKLKMIING RYEIDDDEYS RIREAHGFVD EENRINGVIG 120

SSRQIGHFST FPVVLPTHSY RNIQLNEQIE GLIVGNNMIW NMLSIDDLNS TFHNNRSPIV 180

VAKKIQDQLQ 190

Keyword

Complete proteome; Hydrolase; Leucine-rich repeat; Manganese; Metal-binding; Protein phosphatase; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>