EKS-CAE-00053

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAE-00053

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PIM	418.7	1.2E-125	31	285	255

Status

Unreviewed

Ensembl Protein

F45H7.4.1

UniProt Accession

Q20443;

Protein Name

Protein Synonyms/Alias

Protein PRK-2;

Gene Name

prk-2

Gene Synonyms/Alias

prk-2; CELE_F45H7.4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
F45H7.4	F45H7.4.1	F45H7.4.1
F45H7.4	F45H7.4.2	F45H7.4.2

Organism

Caenorhabditis elegans

Functional Description

Protein Length

441

Protein Sequence
(FASTA)

MKKLASLQFF NLKLLLNGES SRGFSKFKKN YKLKAELGRG GFGVVYRAVR TCDNALVAVK 60

FIERSNVKEW ARINGEQVPM EICMLAKCSK VRGVIRLLDW YSIPEGFLIV MERPYPCIDM 120

FDFIKGQGKI SEDMARFLFR QIAVTVHECV QNRVLHRDLK DENIVIDLVT GSTKLIDFGA 180

ATVLRRSQYS DFQGTRLYCP PEWFLHSLYL GREAAVWSLG VLLYNSLNGR LPFRNEKDIC 240

TAHLLGPLPF FVPVSAEVKD LISKCLTFDP FQRCSLEAIL NHPWVKQQTL SWDALTKNKV 300

QKKTSESSDD HHSETLGDHS ETEEDRSPPT SSVSQQPGSA DEGVGLSASS SNTHNQKKPN 360

HKEFRMAKTS LLAPPTSIEM KAAVQASKTP TQFNVHTALK NQRQIKKHHS PQPPNSTVLT 420

ALRRAMSREA QNRISGVFSQ D 441

Nucleotide Sequence
(FASTA)

ATGAAGAAGC TGGCTTCACT GCAGTTCTTC AATCTGAAAC TTTTACTGAA TGGAGAATCA 60

AGTCGTGGCT TCTCAAAGTT TAAGAAGAAC TATAAGCTGA AAGCAGAGTT GGGAAGAGGT 120

GGATTCGGAG TTGTATACAG AGCTGTCAGG ACTTGTGATA ATGCACTTGT TGCAGTGAAA 180

TTCATCGAGA GAAGCAATGT TAAAGAATGG GCAAGGATAA ACGGCGAACA AGTCCCAATG 240

GAGATTTGCA TGCTCGCCAA ATGCTCAAAA GTGCGAGGAG TGATTCGTCT TCTCGACTGG 300

TACAGTATCC CAGAAGGCTT CCTAATTGTC ATGGAACGAC CGTACCCTTG CATTGACATG 360

TTCGATTTTA TTAAGGGACA GGGAAAGATT AGCGAAGATA TGGCAAGATT CTTGTTCAGA 420

CAAATTGCAG TGACTGTTCA TGAATGTGTT CAGAATCGTG TACTTCATAG GGATTTGAAG 480

GACGAAAACA TCGTGATCGA CTTGGTCACC GGCTCCACAA AACTCATCGA TTTCGGCGCG 540

GCCACCGTAC TCCGAAGAAG CCAATACTCT GATTTCCAAG GAACCCGACT CTATTGCCCA 600

CCTGAATGGT TCTTACATTC TCTCTATCTT GGACGAGAAG CTGCTGTCTG GTCGTTGGGA 660

GTACTCTTGT ACAACTCACT CAACGGTCGA CTACCATTCA GAAATGAGAA GGACATTTGT 720

ACGGCACATC TGTTGGGCCC ACTTCCATTC TTTGTTCCTG TTAGTGCAGA GGTTAAAGAT 780

CTGATTAGCA AGTGTCTGAC ATTCGATCCA TTCCAAAGAT GCTCTCTTGA AGCAATTCTT 840

AATCATCCAT GGGTCAAACA ACAGACACTT TCATGGGATG CTTTGACAAA GAATAAGGTT 900

CAGAAGAAGA CATCGGAATC TTCAGATGAC CATCACAGCG AGACTCTCGG TGATCACTCT 960

GAAACCGAGG AGGACAGAAG CCCCCCGACC AGCAGCGTCT CCCAGCAGCC TGGCAGTGCT 1020

GATGAAGGAG TCGGCCTATC AGCGAGTTCT TCGAATACGC ACAACCAGAA AAAGCCGAAC 1080

CACAAAGAGT TCCGAATGGC GAAAACCTCC CTGCTCGCCC CACCCACCTC AATCGAAATG 1140

AAGGCAGCAG TTCAGGCATC AAAAACGCCC ACGCAGTTCA ATGTTCACAC CGCATTAAAG 1200

AATCAGCGAC AAATCAAGAA GCATCACAGC CCGCAGCCAC CCAACTCTAC CGTACTCACC 1260

GCGTTACGAC GGGCAATGTC AAGAGAGGCA CAGAATCGAA TTAGCGGCGT CTTCTCGCAG 1320

GACTAG 1326

Domain Profile

S: 1     ykvgallGkGGfGvvyagvrvadnlpvavkfvekervkewaelngetvplevvllkkvae  60

         yk++a+lG+GGfGvvy++vr++dn+ vavkf+e+++vkewa++nge+vp+e+++l+k+ +

Q: 31    YKLKAELGRGGFGVVYRAVRTCDNALVAVKFIERSNVKEWARINGEQVPMEICMLAKC-S  89

         99********************************************************.9

S: 61    dvrGvirlldwferpegfllvlerpepaqdlfdfitekGaldedlarslfkqvlaavrec  120

         +vrGvirlldw+++pegfl+v+erp+p++d+fdfi+ +G+++ed+ar+lf+q++++v+ec

Q: 90    KVRGVIRLLDWYSIPEGFLIVMERPYPCIDMFDFIKGQGKISEDMARFLFRQIAVTVHEC  149

         ************************************************************

S: 121   hskgvlhrdikdenllidlrrGevklidfGsgallkdtvytdfdGtrvysppewirkhry  180

         ++++vlhrd+kden++idl++G++klidfG++++l++++y+df+Gtr+y+ppew+ +++y

Q: 150   VQNRVLHRDLKDENIVIDLVTGSTKLIDFGAATVLRRSQYSDFQGTRLYCPPEWFLHSLY  209

         ************************************************************

S: 181   lgreatvwslGvllydlvcGdlpfekdeeil....kgelkfraevskevkqlikkclalk  236

         lgrea+vwslGvlly++++G+lpf+++++i+    +g l f++ vs+evk+li+kcl+++

Q: 210   LGREAAVWSLGVLLYNSLNGRLPFRNEKDICtahlLGPLPFFVPVSAEVKDLISKCLTFD  269

         *******************************777778899********************

S: 237   pserpsleeiaahpwm  252

         p++r+sle+i++hpw+

Q: 270   PFQRCSLEAILNHPWV  285

         ***************7

Domain Sequence
(FASTA)

YKLKAELGRG GFGVVYRAVR TCDNALVAVK FIERSNVKEW ARINGEQVPM EICMLAKCSK 60

VRGVIRLLDW YSIPEGFLIV MERPYPCIDM FDFIKGQGKI SEDMARFLFR QIAVTVHECV 120

QNRVLHRDLK DENIVIDLVT GSTKLIDFGA ATVLRRSQYS DFQGTRLYCP PEWFLHSLYL 180

GREAAVWSLG VLLYNSLNGR LPFRNEKDIC TAHLLGPLPF FVPVSAEVKD LISKCLTFDP 240

FQRCSLEAIL NHPWV 255

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>