EKS-DRM-00144

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DRM-00144

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	379.3	1.5E-113	202	486	285

Status

Unreviewed

Ensembl Protein

FBpp0082436

UniProt Accession

C5WLU3;

Protein Name

Protein Synonyms/Alias

LP03259p;

Gene Name

put-RA

Gene Synonyms/Alias

put-RA;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
FBgn0003169	FBpp0303260	FBtr0330227
FBgn0003169	FBpp0082436	FBtr0082977
FBgn0003169	FBpp0306147	FBtr0334030

Organism

Drosophila melanogaster

Functional Description

Protein Length

516

Protein Sequence
(FASTA)

MSKYDLLYLT AQLTLVCCLI GIHGSILPGS HGIIECEHFD EKMCNTTQQC ETRIEHCKME 60

ADKFPSCYVL WSVNETTGIL RIKMKGCFTD MHECNQTECV TSAEPRQGNI HFCCCKGSRC 120

NSNQKYIKST TEATTQVPKE KTQDGSNLIY IYIGTSVFSV LMVIVGMGLL LYRRRKQAHF 180

NEIPTHEAEI TNSSPLLSNR PIQLLEQKAS GRFGDVWQAK LNNQDVAVKI FRMQEKESWT 240

TEHDIYKLPR MRHPNILEFL GVEKHMDKPE YWLISTYQHN GSLCDYLKSH TISWPELCRI 300

AESMANGLAH LHEEIPASKT DGLKPSIAHR DFKSKNVLLK SDLTACIADF GLAMIFQPGK 360

PCGDTHGQVG TRRYMAPEVL EGAINFNRDA FLRIDVYACG LVLWEMVSRC DFAGPVGEFQ 420

LPFEAELGLR PSLDEVQESV VMKKLRPRLL NSWRAHPGLN VFCDTMEECW DHDAEARLSS 480

SCVMERFAQL NKYPSTQLLI KNHTNIDDAK ESTNCL 516

Nucleotide Sequence
(FASTA)

ATGTCCAAAT ACGATCTGCT TTATCTAACG GCGCAGCTAA CGCTGGTCTG CTGTCTGATT 60

GGAATCCATG GATCTATTTT GCCCGGAAGT CATGGGATCA TAGAATGCGA GCACTTCGAC 120

GAGAAGATGT GCAACACAAC GCAGCAATGT GAAACACGGA TAGAGCACTG TAAGATGGAG 180

GCGGATAAGT TTCCCAGCTG CTATGTCCTT TGGTCGGTCA ACGAGACAAC GGGCATCCTG 240

CGCATCAAGA TGAAGGGCTG CTTCACGGAC ATGCACGAAT GCAATCAGAC GGAGTGCGTG 300

ACCAGTGCAG AGCCACGGCA GGGAAACATT CACTTCTGCT GCTGCAAGGG ATCGCGGTGC 360

AATTCCAACC AGAAATATAT TAAAAGCACC ACGGAGGCAA CCACACAAGT GCCCAAGGAG 420

AAGACGCAGG ACGGCAGCAA TTTGATATAC ATCTACATTG GCACCTCCGT TTTCAGCGTG 480

CTCATGGTCA TTGTTGGCAT GGGCCTTCTT CTCTACCGAC GCCGCAAGCA GGCGCACTTT 540

AACGAGATAC CCACGCACGA GGCTGAGATA ACAAACTCAT CGCCATTGCT CAGCAACCGT 600

CCCATTCAGC TGCTGGAACA GAAGGCCAGT GGTAGATTCG GTGATGTGTG GCAAGCCAAG 660

CTCAACAATC AGGATGTGGC CGTCAAGATC TTTCGCATGC AGGAAAAAGA ATCGTGGACC 720

ACGGAGCACG ATATCTACAA GCTGCCGCGC ATGCGCCATC CGAACATCCT CGAATTCCTG 780

GGCGTTGAGA AGCACATGGA CAAGCCGGAA TATTGGCTGA TATCCACCTA CCAGCATAAC 840

GGATCACTAT GCGACTACCT CAAATCGCAC ACGATCTCAT GGCCAGAGTT GTGCCGCATC 900

GCTGAGTCCA TGGCCAATGG ACTGGCACAT CTGCACGAGG AGATCCCGGC ATCAAAGACC 960

GATGGGCTAA AACCATCGAT AGCTCACCGA GACTTCAAGT CTAAGAACGT ACTGCTTAAG 1020

AGCGATCTGA CGGCCTGTAT AGCTGACTTT GGTTTGGCCA TGATATTCCA GCCAGGCAAG 1080

CCCTGCGGCG ATACACACGG TCAAGTAGGC ACTCGACGTT ACATGGCCCC AGAGGTGCTT 1140

GAGGGTGCCA TCAATTTCAA TAGAGACGCT TTCTTACGCA TAGACGTCTA CGCATGCGGC 1200

CTAGTCCTCT GGGAAATGGT GTCACGGTGT GACTTTGCCG GACCCGTCGG TGAGTTCCAG 1260

CTGCCTTTTG AGGCCGAGCT GGGCCTGAGG CCGTCGCTGG ACGAAGTTCA GGAGAGTGTG 1320

GTAATGAAGA AGCTGCGCCC TCGTTTGCTC AACTCCTGGC GCGCCCATCC GGGACTTAAT 1380

GTATTCTGCG ACACAATGGA GGAGTGCTGG GATCACGACG CTGAGGCTCG TCTTAGCTCT 1440

TCGTGTGTGA TGGAACGCTT TGCGCAGCTA AACAAGTATC CCTCAACCCA GTTGCTAATC 1500

AAGAACCACA CCAACATTGA CGACGCCAAG GAATCTACGA ATTGCTTATA G 1551

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         ++lle+ ++Gr+g+Vw+akl++++vAvKif +++++sw++E++iy+++ +rh+nil+f++

Q: 202   IQLLEQKASGRFGDVWQAKLNNQDVAVKIFRMQEKESWTTEHDIYKLPRMRHPNILEFLG  261

         7899********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

          +k+    + e++l+++y+++gsL+dyLk++t+++ el+r+a+s+a+GlahLHeei+++k

Q: 262   VEKHMD--KPEYWLISTYQHNGSLCDYLKSHTISWPELCRIAESMANGLAHLHEEIPASK  319

         **9543..469*********************************************9887

S: 121   g.kkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaP  179

             Kp+iaHRD+kskN+l+k+dlt+ciaD+GLa+ ++  k   d  ++ qvGt+RYmaP

Q: 320   TdGLKPSIAHRDFKSKNVLLKSDLTACIADFGLAMIFQPGKPCGD--THGQVGTRRYMAP  377

         769***************************************999..79***********

S: 180   EvleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPslee  239

         Evle+a+n+++ +af r+DvY++gLvlWE++sRc+  ++ v e++lpfe+++g +Psl+e

Q: 378   EVLEGAINFNR-DAFLRIDVYACGLVLWEMVSRCDF-AGPVGEFQLPFEAELGLRPSLDE  435

         **********9.9**********************9.9**********************

S: 240   mkevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkr  290

         ++e vv+kklrP++ ++w++++ l+++++++eecWd+d+eaRl++++v +r

Q: 436   VQESVVMKKLRPRLLNSWRAHPGLNVFCDTMEECWDHDAEARLSSSCVMER  486

         ************************************************987

Domain Sequence
(FASTA)

IQLLEQKASG RFGDVWQAKL NNQDVAVKIF RMQEKESWTT EHDIYKLPRM RHPNILEFLG 60

VEKHMDKPEY WLISTYQHNG SLCDYLKSHT ISWPELCRIA ESMANGLAHL HEEIPASKTD 120

GLKPSIAHRD FKSKNVLLKS DLTACIADFG LAMIFQPGKP CGDTHGQVGT RRYMAPEVLE 180

GAINFNRDAF LRIDVYACGL VLWEMVSRCD FAGPVGEFQL PFEAELGLRP SLDEVQESVV 240

MKKLRPRLLN SWRAHPGLNV FCDTMEECWD HDAEARLSSS CVMER 285

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0017002	; F:activin-activated receptor activity
GO:0005524	; F:ATP binding
GO:0004702	; F:receptor signaling protein serine/threonine kinase activity
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0023014	; P:signal transduction by phosphorylation

KEGG

InterPros

IPR000333	; Activin_II/TGFBeta-II_recpt.
IPR015768	; Activin_II_recpt.
IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00653

; ACTIVIN2R.

Created Date

20-Feb-2013