EKS-DRM-00143

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DRM-00143

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	417.0	5.0E-125	229	516	288

Status

Unreviewed

Ensembl Protein

FBpp0087909

UniProt Accession

D5SHT1;

Protein Name

Protein Synonyms/Alias

MIP17172p;

Gene Name

sax-RB

Gene Synonyms/Alias

sax-RB;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
FBgn0003317	FBpp0087908	FBtr0088832
FBgn0003317	FBpp0087909	FBtr0088833
FBgn0003317	FBpp0300982	FBtr0308825

Organism

Drosophila melanogaster

Functional Description

Protein Length

535

Protein Sequence
(FASTA)

MELSSASSAH LNGKELPAVP QNSVQTHPRY KCYSCEPPCR DPYEFTHTCQ NAIQCWKSRT 60

RDADGQVQES RGCSTSPDQL PMICSQNSLK INGPSKRNTG KFVNVVCCAG DYCNEGDFPE 120

LLPFDSNDVT VITADTSSIS KMLVAVLGPF LVIALLGAVT IFFIRRSHRK RLAASRTKQD 180

PEAYLVNDEL LRATSAGDST LREYLQHSVT SGSGSGLPLL VQRTLAKQVT LIECIGRGKY 240

GEVWRGHWHG ESIAVKIFFS RDEESWKRET EIYSTILLRH ENILGFIGSD MTSRNSCTQL 300

WLMTHYYPLG SLFDHLNRNA LSHNDMVWIC LSIANGLVHL HTEIFGKQGK PAMAHRDLKS 360

KNILVTSNGS CVIADFGLAV THSHVTGQLD LGNNPKVGTK RYMAPEVLDE SIDLECFEAL 420

RRTDIYAFGL VLWEVCRRTI SCGIAEEYKV PFYDVVPMDP SFEDMRKVVC IDNYRPSIPN 480

RWSSDSLMTG MSKLMKECWH QNPDVRLPAL RIKKTIHKLA SADEKIRLDF DEVCV 535

Nucleotide Sequence
(FASTA)

ATGGAGCTCT CCTCCGCCTC ATCCGCCCAT CTCAATGGCA AGGAGCTACC GGCCGTGCCA 60

CAGAACTCGG TGCAGACGCA TCCCAGATAC AAATGCTACT CCTGCGAGCC GCCCTGTCGG 120

GATCCCTATG AGTTTACCCA CACCTGCCAG AATGCGATTC AGTGCTGGAA GTCGCGCACA 180

CGCGATGCCG ATGGTCAGGT GCAGGAGTCA CGCGGCTGCA GCACCTCGCC GGATCAACTG 240

CCCATGATCT GCAGCCAGAA CTCCTTGAAG ATCAACGGGC CCAGTAAACG CAATACGGGG 300

AAGTTCGTGA ATGTGGTCTG CTGTGCCGGT GATTACTGCA ATGAGGGAGA CTTTCCGGAA 360

CTGCTGCCCT TCGACAGCAA TGATGTGACG GTGATAACCG CGGATACCAG TAGCATAAGC 420

AAGATGCTCG TCGCCGTTCT GGGTCCTTTT CTGGTCATCG CTCTGCTGGG CGCCGTGACC 480

ATCTTCTTCA TTCGTCGTAG CCATCGCAAG CGTCTGGCTG CCTCGCGAAC CAAACAGGAC 540

CCGGAAGCGT ATCTGGTCAA TGATGAGCTG CTCCGCGCCA CCAGCGCCGG GGACAGTACG 600

CTGAGGGAGT ATCTGCAGCA CTCGGTGACC TCCGGCTCGG GCAGCGGATT GCCGCTGCTA 660

GTGCAGCGTA CGCTAGCCAA ACAGGTCACC CTGATCGAGT GCATTGGACG AGGCAAATAC 720

GGCGAGGTTT GGCGCGGTCA CTGGCATGGC GAAAGCATCG CCGTGAAGAT ATTCTTCAGT 780

CGCGACGAGG AGTCCTGGAA GCGGGAGACA GAGATATATA GCACCATATT GCTACGACAT 840

GAAAATATTC TGGGATTCAT CGGCTCTGAC ATGACGTCGC GGAACTCGTG CACCCAACTT 900

TGGCTGATGA CGCACTACTA TCCACTGGGC TCGCTCTTTG ATCACCTAAA CCGTAACGCC 960

CTAAGCCACA ACGATATGGT ATGGATTTGC CTGTCCATAG CTAATGGGCT GGTACACTTG 1020

CACACAGAGA TATTCGGCAA GCAAGGCAAG CCAGCTATGG CCCACCGCGA TTTGAAGTCA 1080

AAGAATATAC TGGTCACCTC GAACGGCTCC TGCGTGATAG CCGATTTTGG ACTGGCCGTT 1140

ACCCATTCGC ACGTCACAGG ACAACTGGAC CTGGGCAACA ACCCCAAAGT GGGCACCAAG 1200

CGCTACATGG CCCCAGAGGT TCTTGATGAA AGCATTGATT TAGAATGCTT CGAAGCACTA 1260

CGCCGGACAG ATATTTACGC ATTTGGACTT GTCCTCTGGG AGGTTTGTCG CCGCACCATT 1320

TCTTGCGGCA TAGCAGAGGA GTACAAGGTG CCCTTCTACG ATGTGGTGCC AATGGATCCC 1380

AGCTTCGAGG ATATGCGCAA GGTGGTCTGC ATCGACAACT ACAGGCCCTC CATTCCCAAT 1440

CGCTGGAGCT CGGATTCGTT AATGACTGGC ATGTCCAAGC TCATGAAGGA GTGCTGGCAC 1500

CAAAACCCCG ACGTGCGCTT GCCAGCGCTG CGCATCAAAA AGACTATACA TAAGCTGGCT 1560

TCCGCTGACG AGAAGATACG CCTGGACTTC GACGAGGTCT GCGTTTAG 1608

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         ++l+e+ig+G+ygeVw+++++ge++AvKif+++de+swkrE+eiy+t+llrhenil+fi+

Q: 229   VTLIECIGRGKYGEVWRGHWHGESIAVKIFFSRDEESWKRETEIYSTILLRHENILGFIG  288

         589*********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         +d+++++s+t+l+l+t+y++ gsL+d+L+r+ l++++++ ++ls+a+Gl hLH+ei+g++

Q: 289   SDMTSRNSCTQLWLMTHYYPLGSLFDHLNRNALSHNDMVWICLSIANGLVHLHTEIFGKQ  348

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  Kpa+aHRDlkskNilv ++++c+iaD+GLa+++++ + +ldl +n +vGtkRYmaPE

Q: 349   G--KPAMAHRDLKSKNILVTSNGSCVIADFGLAVTHSHVTGQLDLGNNPKVGTKRYMAPE  406

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vl+e+++l++fea++r+D+Y++gLvlWEv++R+ +  +++eeyk+pf++vv+ dPs+e+m

Q: 407   VLDESIDLECFEALRRTDIYAFGLVLWEVCRRTIS-CGIAEEYKVPFYDVVPMDPSFEDM  465

         **********************************9.************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         ++vv+ ++ rP+ip++w++++ ++ +skl++ecW+++p++Rl alr+kk++

Q: 466   RKVVCIDNYRPSIPNRWSSDSLMTGMSKLMKECWHQNPDVRLPALRIKKTI  516

         ************************************************986

Domain Sequence
(FASTA)

VTLIECIGRG KYGEVWRGHW HGESIAVKIF FSRDEESWKR ETEIYSTILL RHENILGFIG 60

SDMTSRNSCT QLWLMTHYYP LGSLFDHLNR NALSHNDMVW ICLSIANGLV HLHTEIFGKQ 120

GKPAMAHRDL KSKNILVTSN GSCVIADFGL AVTHSHVTGQ LDLGNNPKVG TKRYMAPEVL 180

DESIDLECFE ALRRTDIYAF GLVLWEVCRR TISCGIAEEY KVPFYDVVPM DPSFEDMRKV 240

VCIDNYRPSI PNRWSSDSLM TGMSKLMKEC WHQNPDVRLP ALRIKKTI 288

Keyword

ATP-binding; Kinase; Nucleotide-binding; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013