| Tag | Content |
|---|
| EKPD ID | EKS-DRM-00116 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| STE/STE7 | 374.3 | 4.4E-112 | 87 | 364 | 278 |
|
| Status | Reviewed |
| Ensembl Protein | FBpp0071248 |
| UniProt Accession | Q24324; Q8ISE0; Q9W360; |
| Protein Name | Dual specificity mitogen-activated protein kinase kinase dSOR1 |
| Protein Synonyms/Alias | Downstream of RAF; MAPKK; |
| Gene Name | Dsor1 |
| Gene Synonyms/Alias | Dsor1; CG15793; |
| Ensembl Information | |
| Organism | Drosophila melanogaster |
| Functional Description | Required downstream of Raf in the sevenless (sev), torso(tor), and Drosophila EGF receptor homolog (DER) signal transduction pathways. Involved in both positive regulation (at the posterior terminus) and negative regulation (at the anterior domain) of tll, as in other terminal class gene products, maybe via the ERK-A kinase. |
| Protein Length | 396 |
Protein Sequence
(FASTA) | | MSKNKLNLVL PPVNTEATVA AATVAPTPPF KTPSGTDTHS LLGKPKTSID ALTETLEGLD 60 | | MGDTERKRIK MFLSQKEKIG ELSDEDLEKL GELGSGNGGV VMKVRHTHTH LIMARKLIHL 120 | | EVKPAIKKQI LRELKVLHEC NFPHIVGFYG AFYSDGEISI CMEYMDGGSL DLILKRAGRI 180 | | PESILGRITL AVLKGLSYLR DNHAIIHRDV KPSNILVNSS GEIKICDFGV SGQLIDSMAN 240 | | SFVGTRSYMS PERLQGTHYS VQSDIWSLGL SLVEMAIGMY PIPPPNTATL ESIFADNAEE 300 | | SGQPTDEPRA MAIFELLDYI VNEPPPKLEH KIFSTEFKDF VDICLKKQPD ERADLKTLLS 360 | | HPWIRKAELE EVDISGWVCK TMDLPPSTPK RNTSPN 396 |
|
Nucleotide Sequence
(FASTA) | | ATGTCGAAGA ACAAGCTGAA TCTGGTGCTG CCGCCGGTAA ATACGGAGGC AACTGTTGCC 60 | | GCCGCCACAG TGGCGCCGAC GCCGCCATTC AAAACCCCCT CGGGCACAGA CACACACAGT 120 | | TTGCTGGGGA AGCCCAAGAC GAGCATCGAT GCGCTGACAG AGACGCTGGA GGGTCTGGAC 180 | | ATGGGCGACA CGGAACGCAA GCGGATCAAG ATGTTCCTCA GCCAGAAGGA GAAGATCGGC 240 | | GAGCTGTCCG ACGAGGATCT GGAGAAGCTG GGCGAGCTCG GATCGGGCAA TGGCGGCGTG 300 | | GTGATGAAGG TCCGGCACAC GCACACACAC CTGATCATGG CCAGGAAACT GATCCATCTG 360 | | GAGGTGAAGC CGGCGATCAA GAAACAGATC CTGCGCGAAC TGAAAGTCCT GCACGAATGT 420 | | AATTTCCCGC ACATTGTCGG TTTCTACGGC GCCTTCTACA GCGACGGCGA GATCAGTATC 480 | | TGCATGGAGT ATATGGACGG TGGATCACTT GACCTGATCC TCAAGCGGGC CGGTCGAATA 540 | | CCAGAGTCCA TTCTCGGCAG GATCACGCTG GCGGTGCTCA AGGGCTTGAG CTATCTGCGC 600 | | GACAATCACG CCATCATCCA CCGTGACGTG AAGCCGAGCA ATATCCTCGT CAATAGCAGC 660 | | GGCGAGATCA AGATCTGTGA TTTCGGCGTC TCCGGTCAAC TGATCGACTC GATGGCCAAC 720 | | TCCTTTGTGG GCACCCGTAG CTATATGTCG CCGGAGCGAT TGCAGGGCAC CCACTACTCC 780 | | GTGCAGTCGG ACATCTGGTC GTTGGGTCTG TCGCTGGTGG AGATGGCCAT CGGCATGTAC 840 | | CCCATCCCGC CGCCAAACAC CGCCACCCTG GAGTCGATAT TCGCCGACAA TGCGGAGGAG 900 | | AGCGGCCAGC CGACGGACGA GCCCAGGGCA ATGGCCATCT TCGAGCTGCT GGATTATATT 960 | | GTAAACGAAC CGCCGCCCAA GCTAGAGCAC AAGATCTTCT CCACCGAGTT CAAGGACTTC 1020 | | GTGGACATCT GCCTGAAGAA ACAGCCCGAC GAGCGGGCAG ATCTCAAGAC CCTGCTGAGT 1080 | | CATCCGTGGA TACGCAAGGC GGAATTGGAG GAGGTGGATA TATCCGGCTG GGTGTGCAAG 1140 | | ACAATGGACC TGCCGCCATC GACGCCAAAG CGTAATACGT CGCCCAACTA G 1191 |
|
| Domain Profile | S: 1 lekleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyi 60 | lekl+elG+GnggvV+kv+h++++ i+a+K i+le+k++++kqilrel+vl+++ n p+i | Q: 87 LEKLGELGSGNGGVVMKVRHTHTHLIMARKLIHLEVKPAIKKQILRELKVLHEC-NFPHI 145 | 7899**************************************************.***** |
| S: 61 vkfyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylke 120 | v+fyGaf+s+g++sicme+mdg+sld +lk+ ++ripe++lg+i++av+k+l+yl++ | Q: 146 VGFYGAFYSDGEISICMEYMDGGSLDLILKR----AGRIPESILGRITLAVLKGLSYLRD 201 | ******************************9....8************************ |
| S: 121 klkiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksavGtksYmaPEriegkkkYs 180 | ++ iiHRDvKPsNiLvns+Ge+K+CDFGvsgql+ds+A+s+vGt+sYm+PEr++g ++Ys | Q: 202 NHAIIHRDVKPSNILVNSSGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQG-THYS 260 | *******************************************************.**** |
| S: 181 vksdvWslGltlvelatgrypyeklke.........................ilellkai 215 | v+sd+WslGl+lve+a+g yp++++++ i+ell++i | Q: 261 VQSDIWSLGLSLVEMAIGMYPIPPPNTatlesifadnaeesgqptdepramaIFELLDYI 320 | **************************9********************************* |
| S: 216 vneeppklpeeefseefqefvskClkkdekeRpklkellkhafi 259 | vne+ppkl+++ fs+ef++fv+ Clkk+++eR++lk+ll+h++i | Q: 321 VNEPPPKLEHKIFSTEFKDFVDICLKKQPDERADLKTLLSHPWI 364 | ******************************************97 |
|
Domain Sequence
(FASTA) | | LEKLGELGSG NGGVVMKVRH THTHLIMARK LIHLEVKPAI KKQILRELKV LHECNFPHIV 60 | | GFYGAFYSDG EISICMEYMD GGSLDLILKR AGRIPESILG RITLAVLKGL SYLRDNHAII 120 | | HRDVKPSNIL VNSSGEIKIC DFGVSGQLID SMANSFVGTR SYMSPERLQG THYSVQSDIW 180 | | SLGLSLVEMA IGMYPIPPPN TATLESIFAD NAEESGQPTD EPRAMAIFEL LDYIVNEPPP 240 | | KLEHKIFSTE FKDFVDICLK KQPDERADLK TLLSHPWI 278 |
|
| Keyword | ATP-binding; Complete proteome; Developmental protein; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase; Tyrosine-protein kinase. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |