EKS-DRM-00029

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DRM-00029

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	355.0	3.5E-106	53	337	285

Status

Unreviewed

Ensembl Protein

FBpp0087515

UniProt Accession

C6SUX7;

Protein Name

Protein Synonyms/Alias

GM29110p;

Gene Name

cdc2rk-RA

Gene Synonyms/Alias

cdc2rk-RA;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
FBgn0013435	FBpp0087515	FBtr0088429

Organism

Drosophila melanogaster

Functional Description

Protein Length

387

Protein Sequence
(FASTA)

MSSLKSNDVD TNPAPDPQAP ITRKGFLMSL NTGTPMPIPE QNLFGRCRPV SEFEKLNRVG 60

EGSYGIVYRA RDTRSNEIVA LKKVRMDQEK DGLPISGLRE IMILKQCHHE NIVRLREVVV 120

GKSLDSIFLV MDFCEQDLAS VLDNMSQPFT ESEVKCITLQ VLKALKYLHS RFMIHRDLKV 180

SNLLMTDKGC IKVADFGLAR MFSNPPKPMT PQMVTLWYRA PELLLGCRTH TTAVDMWAFG 240

CILGELLLGK PLLPGNSEIA QLDMIIDLLG APSESIWPGF ADLPAVQNFT LSQQPYNNLT 300

PKFHMIGQSG RNLLNILFIY NPKTRATAEE CLKSKYFVDP PQACDPGMMP TFPQHRNNAA 360

PAPAVQPPAD IPISDLLNVF IKRQRME 387

Nucleotide Sequence
(FASTA)

ATGTCCAGCT TAAAGTCAAA CGATGTGGAC ACCAATCCCG CGCCGGATCC CCAGGCGCCC 60

ATTACCCGGA AGGGCTTCCT AATGTCGCTT AACACCGGAA CACCCATGCC GATTCCCGAG 120

CAGAATCTGT TTGGCCGCTG TCGTCCTGTC TCCGAATTCG AGAAACTGAA CCGCGTTGGC 180

GAGGGCAGCT ATGGAATTGT CTATCGCGCA CGTGACACTC GTAGCAATGA GATTGTGGCC 240

TTAAAGAAGG TCCGCATGGA TCAGGAAAAG GATGGTCTGC CAATTAGTGG ACTCCGCGAG 300

ATCATGATCC TAAAGCAGTG CCATCATGAG AATATTGTCC GCTTGCGTGA GGTGGTGGTG 360

GGCAAAAGCT TGGACAGCAT CTTCCTGGTA ATGGATTTCT GCGAGCAGGA CCTAGCCTCC 420

GTGCTAGACA ACATGTCGCA GCCCTTCACC GAGTCCGAGG TTAAGTGCAT CACCTTGCAG 480

GTGCTTAAAG CCTTGAAATA TCTCCATTCG CGCTTTATGA TCCATAGGGA TCTAAAGGTA 540

TCCAATCTGC TGATGACCGA CAAGGGCTGC ATTAAAGTTG CTGATTTTGG ACTGGCCCGC 600

ATGTTTAGCA ATCCCCCGAA ACCAATGACT CCACAGATGG TTACTTTGTG GTACCGGGCA 660

CCTGAACTTC TTTTGGGATG CCGAACACAC ACCACGGCGG TGGATATGTG GGCTTTTGGC 720

TGCATTCTTG GTGAGCTGCT GCTCGGAAAA CCTTTGCTGC CGGGTAATTC GGAGATAGCA 780

CAGCTGGACA TGATCATCGA TCTCTTGGGA GCTCCATCGG AGTCCATTTG GCCTGGCTTT 840

GCCGATCTGC CCGCTGTACA AAATTTTACC TTAAGTCAGC AGCCCTACAA TAACCTTACG 900

CCGAAGTTTC ACATGATTGG CCAATCAGGC AGGAATCTCC TGAACATTTT GTTTATCTAT 960

AACCCAAAAA CGAGAGCCAC GGCCGAAGAG TGCCTGAAAA GCAAGTACTT TGTCGATCCG 1020

CCGCAGGCTT GTGACCCGGG CATGATGCCC ACTTTCCCTC AGCACAGGAA CAATGCTGCA 1080

CCTGCTCCAG CTGTCCAGCC TCCCGCCGAC ATTCCCATCT CGGATTTACT CAATGTATTT 1140

ATTAAGCGTC AACGCATGGA GTAA 1164

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         +ekl+++geG+yg vy+a+d++++e+vAlKk+r+++ek+g+pi+ lrEi +lk+++h+ni

Q: 53    FEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENI  112

         89**********************************************************

S: 61    vkLlevva.kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsn  119

         v+L evv+ k+ ++++Lv++f+eqdL+++l+++++  ++++evk ++lq+l++l+ylHs+

Q: 113   VRLREVVVgKSLDSIFLVMDFCEQDLASVLDNMSQ-PFTESEVKCITLQVLKALKYLHSR  171

         ********5555***********************.************************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYs  179

          ++HRDlK +NlL++++g++k+aDfGlar fs+p k +t+++vTlwYraPelLlg+++++

Q: 172   FMIHRDLKVSNLLMTDKGCIKVADFGLARMFSNPPKPMTPQMVTLWYRAPELLLGCRTHT  231

         ************************************************************

S: 180   tavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksf  238

         tavD+W+ gcil ell  kpl++g+sei ql++i++llg pse++wp++ +lp ++  ++

Q: 232   TAVDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQnFTL  291

         ********************************************************7799

S: 239   pkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         +++++++l+ k++ + +++++ll+ l+ ++pk+R +a+e+l++kyf

Q: 292   SQQPYNNLTPKFHMIGQSGRNLLNILFIYNPKTRATAEECLKSKYF  337

         999999***************************************9

Domain Sequence
(FASTA)

FEKLNRVGEG SYGIVYRARD TRSNEIVALK KVRMDQEKDG LPISGLREIM ILKQCHHENI 60

VRLREVVVGK SLDSIFLVMD FCEQDLASVL DNMSQPFTES EVKCITLQVL KALKYLHSRF 120

MIHRDLKVSN LLMTDKGCIK VADFGLARMF SNPPKPMTPQ MVTLWYRAPE LLLGCRTHTT 180

AVDMWAFGCI LGELLLGKPL LPGNSEIAQL DMIIDLLGAP SESIWPGFAD LPAVQNFTLS 240

QQPYNNLTPK FHMIGQSGRN LLNILFIYNP KTRATAEECL KSKYF 285

Keyword

ATP-binding; Nucleotide-binding.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013