EKS-DRM-00090

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DRM-00090

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/SRPK	350.1	3.1E-104	263	606	344

Status

Unreviewed

Ensembl Protein

FBpp0086517

UniProt Accession

G2J5W6;

Protein Name

Protein Synonyms/Alias

RE75274p1;

Gene Name

SRPK-RA

Gene Synonyms/Alias

SRPK-RA;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
FBgn0026370	FBpp0303478	FBtr0330628
FBgn0026370	FBpp0086515	FBtr0087383
FBgn0026370	FBpp0086516	FBtr0087384
FBgn0026370	FBpp0086517	FBtr0087385

Organism

Drosophila melanogaster

Functional Description

Protein Length

607

Protein Sequence
(FASTA)

MDYEPSDKII DRYHVIRKLG WGHFSTVWLC WDLQAMGYVA IKIVKSAPHF AETARDEIKI 60

LKTVRETDPS NPRRHKTVQM LDDFKITGVN GTHICMVFEV LGDNLLKLIR KSNYRGIPLA 120

NVKTITRQVL EGLDYLHTCC KIIHTDIKPE NVLLCVDEPH VRSLATEATQ LYCMNSKMYP 180

SLVSRAPKEY REPPITGKMS KNRKKKLKKK AKKRMELFKQ QRDYLEQADG QGAINPNEVQ 240

NGDAGISDAD EYFDANSVED NVHVAAGQPS RKQREERKAP PEQSEEAQEQ DPLTEGTDKA 300

KKKKKKKNKN KSNQSKGQQP PQLENSTSSA ESSSALKSQQ ANGSNSTTNN KSNTNSSGTL 360

KGQSNGKKMP LRPKQEKQGS NHQLNNNNSK PNSNSDSKIS SGSVENTSSA TNGPHSNSTL 420

PTPPPPPQAK HKAKKDPALD ECNVHVKIAD LGNACWVDRH FTEDIQTRQY RSLEVIIGAG 480

YNTSADIWST ACMVFELATG DYLFEPHSGE SYTRDEDHLA HIIELLGPIP REILLNGTYA 540

AKSFTRSCEL RNISGLKPWG LMDVLLEKYE WSQKDAASFA SFLTPMLEFD PNKRATAAEC 600

LQHPWLR 607

Nucleotide Sequence
(FASTA)

ATGGATTATG AGCCATCCGA TAAGATCATT GATCGCTACC ATGTCATCCG AAAATTGGGC 60

TGGGGCCACT TTTCAACTGT TTGGCTGTGC TGGGATTTGC AAGCAATGGG ATATGTGGCA 120

ATTAAAATTG TCAAGTCGGC ACCGCACTTT GCCGAGACGG CAAGAGACGA GATAAAGATA 180

CTCAAGACTG TGCGCGAGAC CGATCCATCG AATCCACGCC GTCACAAAAC CGTCCAGATG 240

CTGGACGACT TCAAGATTAC CGGCGTTAAT GGCACCCATA TTTGTATGGT GTTCGAGGTG 300

CTTGGTGACA ATCTGCTGAA ACTCATCCGG AAGTCCAACT ACCGCGGTAT TCCGCTGGCC 360

AACGTCAAAA CTATTACCCG CCAGGTGCTG GAGGGTCTTG ACTATCTTCA CACGTGCTGC 420

AAGATCATCC ACACGGACAT AAAGCCCGAG AATGTCCTCC TGTGCGTGGA CGAGCCTCAT 480

GTGCGCTCAC TAGCAACTGA AGCCACCCAG TTGTATTGCA TGAACTCAAA GATGTACCCC 540

TCCTTGGTGA GCAGGGCGCC CAAGGAGTAT CGTGAGCCAC CTATTACTGG CAAAATGAGC 600

AAGAACCGGA AGAAGAAGCT TAAGAAGAAG GCCAAGAAGC GCATGGAGCT ATTCAAGCAG 660

CAGAGGGACT ACTTGGAGCA GGCTGATGGC CAAGGAGCCA TCAATCCTAA TGAGGTGCAG 720

AACGGCGACG CCGGAATCTC CGATGCTGAT GAATACTTTG ATGCAAACTC TGTGGAGGAT 780

AACGTGCACG TGGCCGCTGG GCAGCCATCG CGTAAGCAGA GGGAGGAGCG CAAGGCGCCC 840

CCGGAGCAAA GTGAGGAGGC GCAGGAGCAG GATCCGCTGA CTGAGGGCAC TGACAAAGCC 900

AAAAAGAAGA AGAAAAAGAA GAACAAAAAC AAATCTAATC AATCAAAAGG GCAACAGCCG 960

CCACAACTGG AAAACTCTAC CAGCAGTGCC GAGAGCAGCA GTGCGCTCAA GAGTCAACAG 1020

GCTAATGGCA GTAATAGCAC TACCAACAAT AAATCCAACA CCAATTCAAG TGGCACCTTG 1080

AAAGGACAAT CAAACGGCAA AAAAATGCCA TTGCGACCCA AGCAGGAGAA GCAGGGATCA 1140

AACCATCAGC TAAACAACAA CAACTCTAAG CCTAACTCGA ACAGCGATTC AAAAATCTCA 1200

AGCGGCTCCG TGGAGAATAC ATCCTCGGCT ACGAATGGAC CGCATTCGAA TTCAACGCTG 1260

CCAACACCTC CTCCGCCGCC GCAAGCAAAG CACAAGGCTA AAAAGGATCC GGCGTTAGAT 1320

GAATGCAACG TCCACGTAAA GATCGCCGAT CTGGGCAACG CTTGTTGGGT GGATCGTCAC 1380

TTCACCGAGG ACATTCAAAC GCGCCAATAT CGGTCACTAG AAGTTATTAT CGGTGCGGGC 1440

TATAACACCT CGGCGGATAT TTGGAGCACT GCATGCATGG TATTCGAATT GGCCACCGGT 1500

GACTATCTGT TTGAGCCACA CTCCGGCGAA TCGTACACCC GCGACGAGGA CCATTTGGCC 1560

CACATCATCG AGCTGCTGGG TCCAATACCG CGGGAGATTT TGTTAAACGG CACATATGCG 1620

GCGAAGTCGT TTACCCGTTC CTGCGAGCTA CGAAATATCT CGGGCCTTAA GCCCTGGGGC 1680

CTAATGGACG TTCTTCTGGA GAAGTACGAG TGGTCGCAAA AGGATGCGGC GTCATTCGCT 1740

TCGTTCCTTA CGCCCATGCT CGAGTTCGAT CCGAACAAGC GAGCCACCGC TGCGGAGTGT 1800

CTGCAGCACC CGTGGCTTAG ATAA 1824

Domain Profile

S: 150   rrlaaeatewqkagakpp...sgsavstapqkkaieklsknkkkklkkkqkr....qael  202

         +  a + +  q+ + k+p   s++a +  p    ++k  k+kkkk k+k ++    q  +

Q: 263   HVAAGQPSRKQREERKAPpeqSEEAQEQDPLTEGTDKAKKKKKKKNKNKSNQskgqQPPQ  322

         555555566666665555111344444444455555555555555555443311112334

S: 203   lekrlqelee...leaaeanseaedqelkedaekgeleeieadveeevanedeaseeee.  258

         le+     e    l++++an++   +++k ++++ ++ + +++ ++     ++ ++ ++

Q: 323   LENSTSSAESssaLKSQQANGSNSTTNNKSNTNSSGTLKGQSNGKKMPLRPKQEKQGSNh  382

         444444433311133333333333344444444443333333333333332222222221

S: 259   essltsssdaesksgelseastellsesleqlacgsvls..........vnplepknad.  307

         + +  +s+ ++++ ++ s+ s+e +s++++  +++s+l+              +p   +

Q: 383   QLNNNNSKPNSNSDSKISSGSVENTSSATNGPHSNSTLPtpppppqakhKAKKDPALDEc  442

         222222223333334446666677777777777777777555555544433344444447

S: 308   kikvkiadLGnaCwvhkhftediqtrqyrslevliGagygtpadiWstaClafeLatGdy  367

         +++vkiadLGnaCwv++hftediqtrqyrslev+iGagy+t+adiWstaC++feLatGdy

Q: 443   NVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDY  502

         899*********************************************************

S: 368   LfephsgedysrdedhiakiiellGkiPrklilkGkysreffnkkgeLrhitkLkpwsLl  427

         Lfephsge+y+rdedh+a+iiellG iPr+++l+G+y+ + f++++eLr+i+ Lkpw+L+

Q: 503   LFEPHSGESYTRDEDHLAHIIELLGPIPREILLNGTYAAKSFTRSCELRNISGLKPWGLM  562

         ************************************************************

S: 428   evLvekyewskeeaaefsdfLlPmleldpekrasaaeclkhpwL  471

         +vL+ekyews+++aa+f++fL+Pmle+dp+kra+aaecl+hpwL

Q: 563   DVLLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAECLQHPWL  606

         *******************************************8

Domain Sequence
(FASTA)

HVAAGQPSRK QREERKAPPE QSEEAQEQDP LTEGTDKAKK KKKKKNKNKS NQSKGQQPPQ 60

LENSTSSAES SSALKSQQAN GSNSTTNNKS NTNSSGTLKG QSNGKKMPLR PKQEKQGSNH 120

QLNNNNSKPN SNSDSKISSG SVENTSSATN GPHSNSTLPT PPPPPQAKHK AKKDPALDEC 180

NVHVKIADLG NACWVDRHFT EDIQTRQYRS LEVIIGAGYN TSADIWSTAC MVFELATGDY 240

LFEPHSGESY TRDEDHLAHI IELLGPIPRE ILLNGTYAAK SFTRSCELRN ISGLKPWGLM 300

DVLLEKYEWS QKDAASFASF LTPMLEFDPN KRATAAECLQ HPWL 344

Keyword

ATP-binding; Kinase; Nucleotide-binding; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>