EPS-DRM-00016

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-DRM-00016

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	165.2	3.2E-48	248	427	180

Status

Unreviewed

Ensembl Protein

FBpp0303677

UniProt Accession

Q9XZ28;

Protein Name

Protein Synonyms/Alias

CG7115, isoform A; CG7115, isoform B;

Gene Name

CG7115

Gene Synonyms/Alias

CG7115, Dmel_CG7115;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
FBgn0027515	FBpp0079146	FBtr0079523
FBgn0027515	FBpp0079147	FBtr0079524
FBgn0027515	FBpp0303676	FBtr0331234
FBgn0027515	FBpp0303678	FBtr0331236
FBgn0027515	FBpp0303677	FBtr0331235

Organism

Drosophila melanogaster

Functional Description

Protein Length

471

Protein Sequence
(FASTA)

MDHRYRRSLR SSAAVDVWSR SILGRIQATL GRQKAVKMME LSASAGDHQS WEEMKQQSSA 60

FAVLGRRPRM EDRFIIEENI NNNTGISFFA VFDGHGGEFA ADFAKDVLVK NIYNKIIEMS 120

KLLKTEGNSG DYDKSPYLAR KQSRKDANKE NTEPTAGVMR KDSLRKAHST TADCSAIKQK 180

TTEASIADIY TVQLNSAMRA SGNLGAAKDS FLNNNNNGQN GAANAPPPNY EAKCYIEHGR 240

INFGKLITDE IMSADYKLVE QAKRATNIAG TTALIAIVQG SKLIVANVGD SRGVMYDWRG 300

IAIPLSFDHK PQQVRERKRI HDAGGFIAFR GVWRVAGVLA TSRALGDYPL KDKNLVIATP 360

DILTFELNDH KPHFLILASD GLWDTFSNEE ACTFALEHLK EPDFGAKSLA MESYKRGSVD 420

NITVLVIVFK NDVYKIGSSA GKAGEESLKV PAKSQPVAPA VVQRSNSIKT K 471

Nucleotide Sequence
(FASTA)

ATGGATCACC GTTACAGAAG ATCGTTAAGG AGCTCAGCAG CGGTAGATGT GTGGAGTCGC 60

AGCATCCTGG GACGCATCCA GGCAACCCTC GGTCGCCAGA AGGCCGTCAA GATGATGGAG 120

CTGTCGGCCA GTGCTGGTGA TCACCAGAGC TGGGAGGAGA TGAAGCAGCA GAGCTCGGCC 180

TTCGCGGTCC TGGGACGCAG GCCAAGAATG GAGGATAGGT TTATTATCGA GGAGAACATC 240

AACAACAACA CTGGTATCTC CTTCTTTGCC GTATTTGACG GTCATGGCGG CGAGTTTGCC 300

GCAGACTTCG CCAAGGATGT GCTGGTGAAG AACATCTACA ATAAGATCAT CGAGATGTCC 360

AAGCTTCTGA AGACGGAAGG AAATTCCGGA GATTACGATA AGAGTCCCTA TTTAGCGCGC 420

AAGCAGAGTC GCAAGGATGC AAACAAGGAG AACACAGAAC CGACGGCAGG GGTGATGCGA 480

AAGGATAGTC TAAGGAAGGC CCACAGCACC ACGGCGGATT GTAGTGCTAT TAAGCAAAAG 540

ACAACCGAGG CATCCATTGC CGACATCTAC ACAGTCCAAT TAAACTCGGC GATGAGAGCC 600

AGTGGGAATT TGGGAGCCGC CAAGGATTCC TTCCTCAACA ACAACAACAA CGGACAGAAC 660

GGAGCAGCCA ATGCGCCACC TCCAAACTAC GAAGCCAAGT GCTACATCGA ACACGGACGT 720

ATTAACTTTG GTAAACTGAT CACGGACGAG ATCATGTCGG CCGACTACAA GCTTGTGGAG 780

CAGGCCAAGA GAGCGACCAA CATTGCGGGA ACCACCGCTC TAATAGCGAT AGTTCAGGGC 840

TCAAAGCTGA TTGTGGCCAA TGTGGGCGAC TCCCGCGGAG TCATGTACGA CTGGCGTGGA 900

ATCGCCATAC CGCTTTCATT CGATCACAAG CCGCAGCAAG TGCGAGAACG AAAGAGAATC 960

CACGATGCAG GCGGATTCAT CGCCTTCCGA GGCGTTTGGC GTGTGGCCGG GGTGTTGGCC 1020

ACGTCACGTG CTCTAGGGGA CTATCCGCTT AAAGATAAGA ATCTGGTGAT TGCTACGCCG 1080

GACATTTTGA CCTTCGAACT AAACGATCAC AAACCCCATT TTCTGATACT GGCATCCGAT 1140

GGGCTGTGGG ACACGTTCAG CAATGAGGAG GCCTGCACTT TTGCGTTGGA GCATCTGAAA 1200

GAGCCGGACT TTGGCGCCAA ATCACTTGCC ATGGAGTCGT ATAAACGTGG CTCCGTGGAC 1260

AACATCACCG TGCTGGTGAT CGTCTTCAAG AACGATGTCT ACAAGATTGG CAGCTCAGCG 1320

GGAAAAGCGG GAGAAGAATC CCTAAAAGTC CCAGCCAAAT CTCAACCAGT TGCGCCTGCA 1380

GTTGTGCAAC GCTCGAATTC AATCAAAACC AAATGA 1416

Domain Profile

S: 80    akaFlstdeelkvleeksldidksGstavvalikdsklyvanvGdSravLcr.ngkavel  138

         ++  +s d +l  +e+++ + +  G+ta++a++++skl+vanvGdSr v+ +  g a++l

Q: 248   TDEIMSADYKL--VEQAKRATNIAGTTALIAIVQGSKLIVANVGDSRGVMYDwRGIAIPL  305

         44445555555..7778788888*****************************7779****

S: 139   ssdHkpsredEleRieeaggsvilkdga.RvlGvLavsRalGdlylk..pyvtpePevts  195

         s dHkp++ +E++Ri +agg ++ + g+ Rv GvLa sRalGd+ lk   +v+++P++

Q: 306   SFDHKPQQVRERKRIHDAGGFIAFR-GVwRVAGVLATSRALGDYPLKdkNLVIATPDILT  364

         *********************9999.777******************9899*********

S: 196   hrltsede.fliLasDGlwdvvsneeavslvrdvlekkeaeqeaakkLvklalargskdn  254

         ++l+  +  fliLasDGlwd++sneea++++ ++l+   +++  ak+L+ ++ +rgs dn

Q: 365   FELNDHKPhFLILASDGLWDTFSNEEACTFALEHLK---EPDFGAKSLAMESYKRGSVDN  421

         ***776666**********************99999...99*******************

S: 255   vsaivv  260

         ++++v+

Q: 422   ITVLVI  427

         *99987

Domain Sequence
(FASTA)

TDEIMSADYK LVEQAKRATN IAGTTALIAI VQGSKLIVAN VGDSRGVMYD WRGIAIPLSF 60

DHKPQQVRER KRIHDAGGFI AFRGVWRVAG VLATSRALGD YPLKDKNLVI ATPDILTFEL 120

NDHKPHFLIL ASDGLWDTFS NEEACTFALE HLKEPDFGAK SLAMESYKRG SVDNITVLVI 180

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0007155	; P:cell adhesion
GO:0006470	; P:protein dephosphorylation
GO:0008360	; P:regulation of cell shape

KEGG

dme:Dmel_CG7115

;

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 2.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013