EKS-DRM-00107

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DRM-00107

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	484.3	1.1E-145	47	332	286

Status

Unreviewed

Ensembl Protein

FBpp0292076

UniProt Accession

Q9VMN3;

Protein Name

Protein Synonyms/Alias

CG7236;

Gene Name

CG7236

Gene Synonyms/Alias

CG7236, Dmel_CG7236;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
FBgn0031730	FBpp0078764	FBtr0079133
FBgn0031730	FBpp0292076	FBtr0302950

Organism

Drosophila melanogaster

Functional Description

Protein Length

435

Protein Sequence
(FASTA)

MCSCLRYQTE KFLNILCAQC KAMRRANIKR GQCLSLRPQG SSKMDRYEKL SRLGEGSYGV 60

VYKCRDRETG ALVAVKRFVE SEDDPAIRKI ALREIRLLKN LKHPNLVSLL EVFRRKRRLH 120

LVFEFCELTV LHELERHPQG CPEHLTKQIC YQTLLGVAYC HKQGCLHRDI KPENILLTAQ 180

GQVKLCDFGF ARMLSPGENY TDYVATRWYR APELLVGDTQ YGTPVDVWAI GCLFAELVRG 240

EALWPGRSDV DQLYLIRKTL GDLLPRHIQI FGQNEYFKGI TLPVPPTLEP LEDKMPAKSQ 300

QNPLTIDFLK KCLDKDPTKR WSCEKLTKHS YFDDYIAKQR ELEHVNSLEA ANLRQQQLAS 360

QQFMLATAAQ QLQTGPAQAA AIAAARDKSK TSNTSLPLLP STQHHHHPHQ DYVKLQPLNK 420

NANLLHRTEH HLPTI 435

Nucleotide Sequence
(FASTA)

ATGTGTTCGT GTCTGAGGTA TCAAACAGAA AAATTCTTGA ACATTTTGTG TGCCCAATGC 60

AAAGCAATGC GACGTGCAAA CATCAAACGT GGTCAATGTT TGAGCTTAAG ACCACAAGGT 120

AGCAGCAAAA TGGATCGCTA TGAGAAGCTC AGTCGGCTGG GCGAGGGCTC CTACGGTGTG 180

GTCTACAAGT GCCGGGATCG GGAAACGGGT GCTCTGGTGG CGGTCAAGAG GTTTGTGGAG 240

TCCGAGGATG ATCCAGCGAT TCGTAAAATT GCACTGCGAG AAATTAGGCT ACTGAAGAAC 300

CTGAAGCATC CGAACCTTGT CTCCCTGCTA GAAGTGTTCC GACGGAAGCG ACGCCTCCAT 360

CTGGTCTTCG AGTTCTGCGA GCTGACCGTG CTGCACGAAC TGGAGCGGCA TCCACAGGGC 420

TGCCCGGAGC ACCTGACCAA ACAGATCTGC TACCAGACCC TGCTGGGCGT GGCCTACTGC 480

CACAAGCAGG GCTGCCTACA CCGCGACATC AAGCCGGAGA ACATTCTGCT GACGGCCCAG 540

GGTCAGGTGA AGCTGTGTGA CTTCGGCTTC GCCCGGATGC TCAGTCCGGG CGAGAATTAC 600

ACGGACTACG TGGCCACCAG ATGGTACCGG GCGCCGGAGC TGCTGGTGGG CGACACTCAG 660

TACGGCACTC CGGTGGACGT CTGGGCCATC GGTTGCCTCT TCGCCGAGCT GGTCCGGGGC 720

GAGGCCCTCT GGCCAGGACG TAGCGATGTG GATCAGCTCT ATCTGATCCG CAAGACGCTC 780

GGCGACCTGC TGCCGCGCCA CATCCAGATC TTTGGACAGA ACGAGTACTT TAAGGGCATC 840

ACGCTGCCAG TGCCGCCGAC GCTGGAGCCG CTGGAGGACA AGATGCCGGC CAAGTCGCAG 900

CAGAATCCCC TGACCATTGA CTTTCTCAAG AAGTGCCTGG ACAAGGATCC GACCAAGCGC 960

TGGTCCTGCG AGAAGCTCAC AAAGCACTCC TACTTCGATG ACTACATCGC TAAGCAGCGC 1020

GAACTGGAGC ACGTCAACAG CCTGGAGGCG GCCAATCTCC GCCAGCAGCA GCTCGCCTCC 1080

CAGCAGTTCA TGCTGGCCAC GGCGGCCCAG CAGCTCCAGA CGGGTCCTGC TCAGGCGGCG 1140

GCCATCGCGG CGGCCCGGGA TAAATCAAAG ACTTCAAACA CATCACTACC GCTGCTGCCT 1200

AGCACGCAGC ATCATCATCA CCCGCATCAA GATTACGTGA AGCTGCAGCC CCTGAACAAG 1260

AATGCAAACC TGCTACATCG CACCGAGCAT CATCTGCCCA CAATTTGA 1308

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yekl+++GeGsyGvv+kcr+++tg +va+k+f+esedd++++kialrei+llk+lkh+nl

Q: 47    YEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNL  106

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         v+llevfrrk++l+lvfe+++ tvl+eler+p+G++e+l+k+i+yq+l ++++chk+ ++

Q: 107   VSLLEVFRRKRRLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCHKQGCL  166

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil++ +g+vklcdfGfar+l+ pg++ytdyvatrwyrapellvgdt+yG++v

Q: 167   HRDIKPENILLTAQGQVKLCDFGFARMLS-PGENYTDYVATRWYRAPELLVGDTQYGTPV  225

         ****************************9.******************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGcl+ael++Ge+l+pg+sdvdqly+irktlG+l+prh++if +ne+f+G++lp +

Q: 226   DVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQIFGQNEYFKGITLPVP  285

         ************************************************************

S: 241   edleslekkyp...klnevlldllkkclkldpaerlsceellkheyf  284

          +le+le+k+p   ++n++++d+lkkcl+ dp++r+sce+l+kh+yf

Q: 286   PTLEPLEDKMPaksQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYF  332

         **********987778999***************************9

Domain Sequence
(FASTA)

YEKLSRLGEG SYGVVYKCRD RETGALVAVK RFVESEDDPA IRKIALREIR LLKNLKHPNL 60

VSLLEVFRRK RRLHLVFEFC ELTVLHELER HPQGCPEHLT KQICYQTLLG VAYCHKQGCL 120

HRDIKPENIL LTAQGQVKLC DFGFARMLSP GENYTDYVAT RWYRAPELLV GDTQYGTPVD 180

VWAIGCLFAE LVRGEALWPG RSDVDQLYLI RKTLGDLLPR HIQIFGQNEY FKGITLPVPP 240

TLEPLEDKMP AKSQQNPLTI DFLKKCLDKD PTKRWSCEKL TKHSYF 286

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004693	; F:cyclin-dependent protein kinase activity
GO:0000910	; P:cytokinesis

KEGG

dme:Dmel_CG7236

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013