EKS-DRM-00066

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DRM-00066

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/CDC7	408.5	2.4E-122	145	597	453

Status

Unreviewed

Ensembl Protein

FBpp0080603

UniProt Accession

Q9VJ90;

Protein Name

Protein Synonyms/Alias

CG5790; FI19424p1;

Gene Name

CG5790-RA

Gene Synonyms/Alias

CG5790-RA; CG5790, Dmel_CG5790;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
FBgn0032677	FBpp0080603	FBtr0081050

Organism

Drosophila melanogaster

Functional Description

Protein Length

665

Protein Sequence
(FASTA)

MDKKEVQHHR SQQAMTKSLY AIGMGLLGKS ATNMDCANTN LESAGKSSST NYNRNRFYNE 60

RFVPMASGTM PSVSGTNHHS RHQQLLLQQA PKCTADLNEK LVKINRQNAN KELSTIQAKD 120

MQSVDKNEEA LKELQESIPE INKIFDVHCR IGSGTFSTVL LGTLQRERGL VETQRRRFAI 180

KHHNPTNHPE RILRELECMY RIGGVENVIG INCCIRYNDN VAFIMPYMTH DRFHDIYRSL 240

NFPEIRDYLR NLLIALRHVH KFNVIHRDVK PSNILYNRRT GKFLLCDFGL AQRIADDGSV 300

VQSSDLSSRE VFSILRDLEN GRSVTLTDGN SAQAEAEDYM ARRRMRALGG GGSVERAVTG 360

PPSIQKLREQ AGGHLTKKDV ANQRADTMRL LNRLRLVSPN ADPNNYVVST NTSKKEMHAS 420

RAGTPGYRPP EVLLRYPKQS TAVDVWAAGV IMLSLLSGLH PFFKAPHDCG ALAEIINLFG 480

DMPVRKTAFL LDRLILLAQK VNTLDLRRVC MRFRHADFFL APEIQRKYQR PDGTTEMCRS 540

CEQPTFNCLC SNSGHNLERY DGLDIFPAVA YDLLSRLLEV NPQKRITAEE ALKHPFFSDQ 600

HRITPGIPLH QQQLIMHQQQ HIMQHQQHLQ RSRETLPSSA ARTLKAFVCY PMEITSTASQ 660

AAGNI 665

Nucleotide Sequence
(FASTA)

ATGGACAAGA AAGAAGTTCA ACATCACCGC AGTCAACAGG CGATGACAAA ATCTCTATAC 60

GCCATTGGGA TGGGTCTTCT GGGAAAGTCG GCGACCAACA TGGATTGTGC TAATACGAAT 120

TTAGAATCGG CAGGGAAGAG CTCCTCAACG AATTATAACA GAAATCGGTT CTACAACGAA 180

AGGTTCGTTC CGATGGCATC CGGAACTATG CCTTCCGTTT CGGGCACTAA CCATCATTCT 240

AGGCATCAAC AGCTCCTTCT CCAACAAGCT CCCAAGTGCA CTGCCGATCT CAACGAGAAA 300

TTAGTAAAAA TCAATCGGCA AAACGCCAAT AAGGAGCTAT CCACCATTCA GGCAAAGGAT 360

ATGCAATCCG TTGATAAAAA CGAAGAGGCC CTAAAAGAAT TGCAGGAGAG CATTCCGGAA 420

ATCAACAAAA TCTTCGATGT GCACTGTCGC ATCGGCAGTG GAACCTTCAG CACAGTTCTC 480

TTGGGAACCC TGCAGCGGGA AAGGGGTCTC GTGGAAACCC AAAGGAGGAG ATTCGCCATC 540

AAACATCATA ATCCCACAAA TCATCCGGAG AGGATTCTTA GAGAGTTGGA GTGCATGTAT 600

CGCATTGGTG GAGTGGAAAA TGTAATCGGA ATTAATTGCT GCATTAGATA TAACGACAAC 660

GTGGCCTTTA TCATGCCCTA TATGACCCAC GATCGCTTTC ACGACATTTA CAGAAGCCTG 720

AATTTCCCAG AGATACGCGA CTATCTGAGG AACTTGCTCA TTGCGCTGCG ACACGTTCAC 780

AAGTTCAATG TGATTCATCG GGACGTCAAG CCAAGTAACA TTCTTTATAA CCGCAGGACC 840

GGAAAGTTTT TACTCTGCGA TTTCGGATTG GCTCAAAGGA TAGCCGATGA TGGTAGTGTA 900

GTGCAGTCGA GTGATCTCAG CTCCCGGGAA GTATTCTCCA TTCTGAGGGA CCTGGAGAAT 960

GGTAGAAGTG TGACGTTGAC GGATGGCAAT TCAGCCCAAG CCGAGGCTGA GGATTATATG 1020

GCCCGTCGAA GGATGCGGGC TCTAGGTGGC GGTGGGAGCG TGGAACGTGC TGTGACTGGA 1080

CCTCCGAGTA TACAGAAACT ACGTGAGCAA GCGGGTGGAC ATTTGACCAA AAAGGATGTG 1140

GCCAACCAGA GGGCTGACAC CATGAGGCTG CTGAACCGCC TGCGACTCGT GAGCCCAAAT 1200

GCGGATCCCA ACAACTACGT GGTCTCCACG AACACCTCGA AGAAGGAGAT GCACGCTTCA 1260

AGGGCTGGAA CCCCAGGATA CAGACCCCCG GAGGTTTTGC TCCGATATCC CAAACAATCC 1320

ACTGCGGTGG ACGTGTGGGC GGCTGGCGTT ATAATGCTCT CTTTGCTCTC TGGTCTTCAT 1380

CCATTTTTCA AGGCCCCCCA CGACTGCGGC GCCCTGGCTG AAATAATCAA CCTATTTGGC 1440

GATATGCCAG TGCGGAAGAC TGCCTTTCTG CTGGATAGGC TGATTTTGCT GGCGCAGAAG 1500

GTGAACACCT TGGATTTACG GAGGGTGTGC ATGCGATTTC GCCATGCGGA CTTCTTTCTG 1560

GCCCCCGAAA TACAACGTAA ATATCAAAGG CCCGATGGCA CCACCGAAAT GTGCCGCAGC 1620

TGTGAGCAGC CCACGTTTAA TTGCCTGTGC AGCAACAGTG GGCATAATTT GGAAAGGTAC 1680

GATGGGCTGG ATATATTTCC CGCAGTGGCC TACGACTTGT TGTCCCGTCT GCTGGAAGTT 1740

AATCCCCAAA AGCGTATCAC CGCCGAGGAG GCCCTAAAGC ATCCGTTCTT CAGCGATCAG 1800

CATCGCATTA CGCCGGGAAT ACCGCTGCAC CAGCAGCAGC TTATAATGCA CCAGCAGCAG 1860

CATATAATGC AGCATCAGCA ACACCTCCAG AGATCCAGAG AGACACTTCC TTCGTCGGCG 1920

GCGCGAACTC TAAAGGCATT CGTATGCTAT CCCATGGAAA TTACTTCTAC TGCGTCACAG 1980

GCAGCGGGTA ACATCTGA 1998

Domain Profile

S: 1     fkikdkiGeGtfssvylataqleeglee....kialkhliptshPeriaaeLelltvlgG  56

         f+++++iG+Gtfs+v+l+t+q+e+gl+e    ++a+kh++pt+hPeri++eLe+++++gG

Q: 145   FDVHCRIGSGTFSTVLLGTLQRERGLVEtqrrRFAIKHHNPTNHPERILRELECMYRIGG  204

         89*************************99999****************************

S: 57    qenvvglkecfrkndsvvivlpylehesfldllrslsfqevreYlrnLlvalkrvhkfgi  116

          env+g+++c+r+nd+v++++py++h++f+d++rsl+f+e+r+YlrnLl+al++vhkf++

Q: 205   VENVIGINCCIRYNDNVAFIMPYMTHDRFHDIYRSLNFPEIRDYLRNLLIALRHVHKFNV  264

         ************************************************************

S: 117   vhrDvkpsnfLynrrlkkfaLvDfGLaq......seaqkeecsrnllsaavekevd....  166

         +hrDvkpsn+Lynrr++kf+L+DfGLaq      s          + s    +ev

Q: 265   IHRDVKPSNILYNRRTGKFLLCDFGLAQriaddgS--------VVQSSDLSSREVFsilr  316

         ****************************5554442........22222222222222233

S: 167   ............................................................  166

Q: 317   dlengrsvtltdgnsaqaeaedymarrrmralggggsveravtgppsiqklreqagghlt  376

         3335566777788888888889999***********************************

S: 167   .....................tcdcygtdkvcsvclsrrqqvanraGtpGfraPevLlki  205

                              + +    + v s   s+++ +a+raGtpG+r+PevLl++

Q: 377   kkdvanqradtmrllnrlrlvSPNADPNNYVVSTNTSKKEMHASRAGTPGYRPPEVLLRY  436

         *******************98888889999******************************

S: 206   pdqttaiDiwsaGvilLsllsgryPffkasddlealaeivtilGsreiikaakafgksvl  265

         p+q+ta+D+w+aGvi+Lsllsg +Pffka++d+ alaei++++G++ ++k+a    + +l

Q: 437   PKQSTAVDVWAAGVIMLSLLSGLHPFFKAPHDCGALAEIINLFGDMPVRKTAFLLDRLIL  496

         ************************************************************

S: 266   lskevp......................................................  271

         l+++v

Q: 497   LAQKVNtldlrrvcmrfrhadfflapeiqrkyqrpdgttemcrsceqptfnclcsnsghn  556

         ******9***********************999999999999998888888887776665

S: 272   ....dsdsyePdeaydlldkllelnPakritaeealkhpff  308

             d  ++ P+ aydll++lle+nP+kritaeealkhpff

Q: 557   leryDGLDIFPAVAYDLLSRLLEVNPQKRITAEEALKHPFF  597

         5554444555******************************8

Domain Sequence
(FASTA)

FDVHCRIGSG TFSTVLLGTL QRERGLVETQ RRRFAIKHHN PTNHPERILR ELECMYRIGG 60

VENVIGINCC IRYNDNVAFI MPYMTHDRFH DIYRSLNFPE IRDYLRNLLI ALRHVHKFNV 120

IHRDVKPSNI LYNRRTGKFL LCDFGLAQRI ADDGSVVQSS DLSSREVFSI LRDLENGRSV 180

TLTDGNSAQA EAEDYMARRR MRALGGGGSV ERAVTGPPSI QKLREQAGGH LTKKDVANQR 240

ADTMRLLNRL RLVSPNADPN NYVVSTNTSK KEMHASRAGT PGYRPPEVLL RYPKQSTAVD 300

VWAAGVIMLS LLSGLHPFFK APHDCGALAE IINLFGDMPV RKTAFLLDRL ILLAQKVNTL 360

DLRRVCMRFR HADFFLAPEI QRKYQRPDGT TEMCRSCEQP TFNCLCSNSG HNLERYDGLD 420

IFPAVAYDLL SRLLEVNPQK RITAEEALKH PFF 453

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004702	; F:receptor signaling protein serine/threonine kinase activity
GO:0006911	; P:phagocytosis, engulfment
GO:0008360	; P:regulation of cell shape

KEGG

dme:Dmel_CG5790

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 2.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013