EKS-DRM-00127

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DRM-00127

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	344.5	4.2E-103	18	269	252

Status

Unreviewed

Ensembl Protein

FBpp0306195

UniProt Accession

Q9VUV4;

Protein Name

Protein Synonyms/Alias

CG6114;

Gene Name

sff

Gene Synonyms/Alias

sff; CG6114, Dmel_CG6114;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
FBgn0036544	FBpp0306195	FBtr0334070
FBgn0036544	FBpp0306196	FBtr0334071
FBgn0036544	FBpp0088511	FBtr0089527

Organism

Drosophila melanogaster

Functional Description

Protein Length

845

Protein Sequence
(FASTA)

MQKENNVTAE NCQFVGPYRL EKTLGKGQTG LVKLGVHCVI GKKVAIKIIN REKLSESVLM 60

KVEREIAIMK LIDHPHVLGL SDVYENKKYL YLILEHVSGG ELFDYLVKKG RLTPKEARKF 120

FRQIISALDF CHSHSICHRD LKPENLLLDE KNNIKIADFG MASLQPAGSM LETSCGSPHY 180

ACPEVIRGEK YDGRKADVWS CGVILYALLV GALPFDDDNL RQLLEKVKRG VFHIPHFVPP 240

DCQSLLRGMI EVNPDRRLTL AEINRHPWVT AGGKGELELE LPMMEVVQTH VIPTATAVDP 300

DVLNAICSLG CFKEKEKLIQ ELLSSSHNTE KVIYFLLLER KRRRPALEDD DEIAQKSRSE 360

LDAVDPPRKR LDTCRINGTN APSYGQISEG SPLTPRRQAF NFRSYSSTRN HQRRSPTTVT 420

SSVRSSSYHS PTRCNSPMSS AQQQANAISR PSSPAAGTRH STYGDRDRSG HHSSVSRTPS 480

HSSQKSIEGD VVVVREPRIE RRDSLRQERG GGSPRDRGDC GIPPGSPGGN SSGSTSASPS 540

VHHRANSVVN PNGSPMMNNS SPGMPGSPCN TPGGQLWKTR LTNIKNSFLG SPRFHRRKMQ 600

VSADEVHLTP ESSPELTKRS WFGNLITTEK DETFTILVKG KPIATVKAHL IHAFLSMAEL 660

SHSVVSPTSF RVEYKRNGNG PVMFQRHVKF QVDISAICKQ GDIADMLFAL TFTLLSGNIR 720

RFRRICEHIQ SQVCSKRFPG PSSPPTVTSV TQAVSESSSC GSVSSERLSY KRQVIENDME 780

NDSIFSYKSG NGRRASTTNN NNANPVDIPG SPIAVRSNSE TAEHERNREL QSERQATTMS 840

GSAIA 845

Nucleotide Sequence
(FASTA)

ATGCAGAAGG AGAACAATGT CACGGCGGAG AATTGCCAAT TTGTGGGGCC CTATCGCCTG 60

GAGAAAACCC TTGGCAAGGG TCAAACGGGT CTCGTCAAGT TGGGCGTGCA TTGTGTGATT 120

GGCAAGAAGG TTGCGATTAA AATAATCAAT CGCGAGAAAC TCAGCGAATC GGTGCTAATG 180

AAGGTTGAAC GTGAAATCGC CATAATGAAA CTAATCGATC ATCCACACGT CCTTGGCCTG 240

AGCGATGTGT ACGAGAACAA GAAGTATTTG TATTTGATAT TGGAGCATGT ATCCGGCGGA 300

GAGCTCTTCG ATTACCTGGT GAAGAAGGGT CGATTGACGC CGAAGGAGGC GCGCAAGTTC 360

TTCAGGCAAA TCATCTCCGC CCTGGATTTC TGCCACTCGC ATTCGATTTG CCATCGCGAC 420

TTGAAGCCGG AGAATCTGCT GCTGGACGAG AAGAATAACA TTAAGATAGC GGACTTTGGG 480

ATGGCTTCCC TGCAGCCAGC TGGCAGCATG TTGGAGACCT CCTGCGGCAG CCCACACTAC 540

GCGTGTCCAG AGGTCATACG GGGCGAGAAG TACGATGGCC GCAAGGCGGA TGTCTGGTCC 600

TGTGGGGTCA TCCTCTATGC CCTCCTGGTG GGTGCGTTGC CCTTCGACGA CGACAACTTG 660

CGCCAGCTGC TGGAGAAAGT CAAGCGGGGC GTCTTTCACA TACCGCACTT TGTGCCGCCG 720

GACTGCCAGA GTCTGCTGCG CGGCATGATT GAGGTCAATC CGGACCGGCG GCTCACGCTG 780

GCTGAAATCA ACCGGCATCC GTGGGTCACA GCTGGCGGCA AAGGGGAGCT GGAGCTGGAG 840

CTGCCAATGA TGGAGGTGGT GCAGACACAC GTTATTCCCA CAGCCACCGC GGTGGATCCG 900

GATGTGTTGA ACGCGATTTG CTCGCTGGGC TGTTTCAAGG AGAAGGAGAA ACTCATCCAG 960

GAACTGCTCA GTTCAAGTCA CAATACGGAG AAGGTTATAT ATTTCCTGTT GCTCGAGCGC 1020

AAACGAAGAC GACCTGCGCT GGAGGATGAT GATGAGATTG CGCAAAAGTC CCGCAGCGAA 1080

CTGGACGCAG TGGATCCGCC GCGTAAGCGT CTGGACACCT GTCGCATCAA TGGCACCAAT 1140

GCACCCAGCT ATGGGCAGAT TTCGGAAGGT TCACCGCTCA CGCCAAGACG ACAGGCCTTT 1200

AATTTCCGGT CGTACAGCAG CACCCGGAAC CACCAACGCC GATCGCCCAC AACAGTTACC 1260

TCGTCGGTGC GGAGCTCCTC ATATCACAGT CCCACGCGCT GCAACTCTCC GATGAGTTCG 1320

GCACAGCAGC AGGCGAATGC CATATCCCGA CCATCTTCTC CGGCGGCGGG CACCCGGCAC 1380

TCTACGTACG GTGATCGAGA TCGTTCCGGA CACCACTCCT CCGTAAGCCG GACACCGTCG 1440

CACAGTTCGC AGAAGAGCAT CGAGGGTGAT GTGGTGGTGG TGCGGGAGCC GAGGATCGAG 1500

CGGAGGGACT CACTGCGTCA GGAGCGCGGC GGAGGATCGC CGAGGGATCG AGGCGATTGC 1560

GGCATACCGC CGGGCAGTCC GGGCGGCAAC TCGAGCGGAT CCACTTCCGC CTCGCCGTCG 1620

GTGCACCACC GTGCCAACTC AGTTGTGAAT CCCAATGGCT CGCCCATGAT GAACAACAGC 1680

AGTCCGGGAA TGCCCGGATC TCCTTGCAAT ACACCTGGTG GTCAGTTGTG GAAGACGCGG 1740

CTGACAAACA TCAAAAACAG TTTCTTGGGC AGTCCGCGGT TCCATCGCAG AAAAATGCAG 1800

GTTTCTGCCG ATGAGGTGCA CTTGACGCCC GAATCTTCGC CAGAGCTTAC AAAGCGCTCC 1860

TGGTTTGGAA ATCTCATAAC AACCGAGAAG GATGAAACCT TTACTATTTT GGTCAAGGGC 1920

AAGCCCATTG CCACGGTTAA GGCGCATTTG ATACACGCAT TTTTATCCAT GGCCGAACTA 1980

TCTCATAGTG TGGTGTCGCC CACCTCGTTT CGGGTGGAGT ACAAGCGGAA TGGCAATGGA 2040

CCTGTCATGT TCCAACGCCA CGTTAAATTC CAGGTTGACA TCAGTGCCAT TTGCAAACAA 2100

GGTGACATAG CGGATATGTT GTTTGCTTTG ACATTTACGC TGCTATCAGG TAACATTCGG 2160

CGTTTTCGGC GCATTTGTGA GCACATCCAA TCCCAGGTGT GTTCCAAGCG ATTTCCGGGT 2220

CCCAGTAGTC CGCCAACGGT GACCAGCGTG ACCCAGGCCG TCTCGGAGAG CTCCTCCTGC 2280

GGATCGGTGT CCAGCGAGAG ATTATCGTAC AAGCGACAGG TGATTGAAAA CGATATGGAG 2340

AACGATTCCA TATTCTCGTA CAAGTCGGGC AATGGACGTC GGGCCTCGAC CACAAATAAC 2400

AATAATGCCA ATCCAGTTGA CATTCCCGGA AGTCCCATTG CAGTGCGATC CAACTCTGAG 2460

ACCGCTGAGC ACGAACGCAA CCGCGAGCTG CAGAGTGAGC GTCAGGCGAC AACGATGTCC 2520

GGTAGTGCAA TCGCATGA 2538

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpni  60

         y+l ktlG+g++g Vkl +h   ++kva+Kii+++klse+ l k++rEi+i+k ++hp++

Q: 18    YRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKVEREIAIMKLIDHPHV  77

         99**********************************************************

S: 61    ikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgiv  120

         + l +v+e+kk+lyl+le++sggeLfdy+++kgrl+ keark+f+q++sa++++hs++i+

Q: 78    LGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSIC  137

         ************************************************************

S: 121   HrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvD  180

         HrDlKpeNllld+k+nikiaDFG+a+l   g++let+cGsp+Ya+Pe+++g+kY+g+k+D

Q: 138   HRDLKPENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKAD  197

         ************************************************************

S: 181   vWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpekR  240

         vWs+Gv+Lyal++g+lPfd++nl++llek+++g ++ip+ + ++++sLlr +++v+p++R

Q: 198   VWSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRR  257

         ************************************************************

S: 241   atieeilkhewl  252

         +t+ ei++h+w+

Q: 258   LTLAEINRHPWV  269

         ***********7

Domain Sequence
(FASTA)

YRLEKTLGKG QTGLVKLGVH CVIGKKVAIK IINREKLSES VLMKVEREIA IMKLIDHPHV 60

LGLSDVYENK KYLYLILEHV SGGELFDYLV KKGRLTPKEA RKFFRQIISA LDFCHSHSIC 120

HRDLKPENLL LDEKNNIKIA DFGMASLQPA GSMLETSCGS PHYACPEVIR GEKYDGRKAD 180

VWSCGVILYA LLVGALPFDD DNLRQLLEKV KRGVFHIPHF VPPDCQSLLR GMIEVNPDRR 240

LTLAEINRHP WV 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007528	; P:neuromuscular junction development
GO:0006487	; P:protein N-linked glycosylation

KEGG

dme:Dmel_CG6114

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013