| Tag | Content |
|---|
| EKPD ID | EPS-DRM-00006 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| DSP/aDSP | 61.1 | 1.4E-16 | 43 | 185 | 143 |
|
| Status | Reviewed |
| Ensembl Protein | FBpp0083845 |
| UniProt Accession | Q86BN8; Q8SZ90; Q9VCI6; |
| Protein Name | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 |
| Protein Synonyms/Alias | PTEN-like protein; Protein-tyrosine phosphatase mitochondrial 1-like protein; |
| Gene Name | Plip |
| Gene Synonyms/Alias | Plip; CG10371; |
| Ensembl Information | |
| Organism | Drosophila melanogaster |
| Functional Description | Lipid phosphatase that may mediate dephosphorylation ofmitochondrial proteins (By similarity). Protein phosphatase that may mediate dephosphorylation of mitochondrial proteins (By similarity). Does not dephosphorylate Akt. |
| Protein Length | 194 |
Protein Sequence
(FASTA) | | MFARVSFYPT LLYNVLMEKA SARNWYDRID EHVILGALPF RSQANDLIEK ENMKAVVSMN 60 | | EDYELTAFSN NTEKWRKLGI EFLQLATTDI FESPNQEKLF RGVEFINKFL PLKQRIGGLS 120 | | SSYQPENVGS VYVHCKAGRT RSATLVGCYL MMKNGWTPDQ AVDHMRKCRP HILLHTKQWD 180 | | ALRLFYTNNV ETKS 194 |
|
Nucleotide Sequence
(FASTA) | | ATGTTCGCAC GCGTTTCCTT CTACCCCACC CTGCTGTACA ATGTCCTGAT GGAAAAGGCA 60 | | TCGGCCAGGA ATTGGTACGA TCGCATCGAT GAGCATGTGA TACTGGGAGC ACTGCCCTTT 120 | | CGCAGCCAGG CCAATGACCT CATTGAAAAG GAGAACATGA AGGCGGTGGT GTCGATGAAC 180 | | GAGGACTATG AGCTGACCGC CTTCTCCAAC AACACGGAGA AGTGGCGAAA GCTTGGCATT 240 | | GAGTTCCTGC AGCTGGCCAC CACCGACATC TTTGAGTCGC CCAATCAAGA AAAGCTCTTC 300 | | CGCGGCGTGG AATTCATAAA CAAGTTCCTG CCTCTAAAGC AAAGAATTGG TGGCCTAAGT 360 | | TCCTCCTACC AGCCGGAGAA CGTGGGTTCT GTCTATGTGC ACTGCAAGGC TGGTAGGACG 420 | | CGAAGTGCCA CTTTGGTGGG ATGCTACCTC ATGATGAAGA ACGGATGGAC TCCGGATCAG 480 | | GCGGTTGACC ACATGCGTAA GTGCCGACCG CACATTCTGC TGCACACCAA ACAATGGGAT 540 | | GCCCTCCGGT TATTCTACAC AAACAATGTG GAGACGAAAT CATGA 585 |
|
| Domain Profile | S: 16 taldrreLsklgitvvinaslsvikvqviPeylikkgityknipvdDsdvtdllqyfdea 75 | +a+d e +++++ v +n + + + e +k gi+++++ D ++ + + + | Q: 43 QANDLIEKENMKAVVSMNEDYELTAFSNNTEKWRKLGIEFLQLATTDIFESPNQEKLFRG 102 | 567777777788999999999999999*****************9999887777777778 |
| S: 76 aefidea...............kekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAi 120 | +efi++ e+ g+v+vHC+aG RSatlv +YLm+ +g++ ++A+ | Q: 103 VEFINKFlplkqrigglsssyqPENVGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAV 162 | 8888888888899******9988889********************************** |
| S: 121 eavkrkrpsiepnegfleQLlel 143 | ++++rp+i ++ L+++ | Q: 163 DHMRKCRPHILLHTKQWDALRLF 185 | *************9999999887 |
|
Domain Sequence
(FASTA) | | QANDLIEKEN MKAVVSMNED YELTAFSNNT EKWRKLGIEF LQLATTDIFE SPNQEKLFRG 60 | | VEFINKFLPL KQRIGGLSSS YQPENVGSVY VHCKAGRTRS ATLVGCYLMM KNGWTPDQAV 120 | | DHMRKCRPHI LLHTKQWDAL RLF 143 |
|
| Keyword | Alternative splicing; Complete proteome; Hydrolase; Lipid biosynthesis; Lipid metabolism; Membrane; Mitochondrion; Mitochondrion inner membrane; Phospholipid biosynthesis; Phospholipid metabolism; Protein phosphatase; Reference proteome; Transit peptide. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | | GO:0005743 | ; C:mitochondrial inner membrane | | GO:0008962 | ; F:phosphatidylglycerophosphatase activity | | GO:0004439 | ; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity | | GO:0004725 | ; F:protein tyrosine phosphatase activity | | GO:0008138 | ; F:protein tyrosine/serine/threonine phosphatase activity | | GO:0006200 | ; P:ATP catabolic process | | GO:0046855 | ; P:inositol phosphate dephosphorylation | | GO:0022008 | ; P:neurogenesis | | GO:0035335 | ; P:peptidyl-tyrosine dephosphorylation | | GO:0006655 | ; P:phosphatidylglycerol biosynthetic process |
|
| KEGG | |
| InterPros | |
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| Created Date | 20-Feb-2013 |