EPS-DRM-00010

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-DRM-00010

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	239.1	8.8E-71	28	279	252

Status

Unreviewed

Ensembl Protein

FBpp0084399

UniProt Accession

B6IDQ9;

Protein Name

Protein Synonyms/Alias

FI06504p;

Gene Name

CG6036-RA

Gene Synonyms/Alias

CG6036-RA;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
FBgn0039421	FBpp0084399	FBtr0085027

Organism

Drosophila melanogaster

Functional Description

Protein Length

371

Protein Sequence
(FASTA)

MGHKMGGFLE KPETEKQAQE GHGNGLRYCV SSMQGWRLEM EDSHSAACRL KDPFATWSYF 60

AVFDGHAGSQ ISLHCAEHLM STILESESFS KHKYEAGIRE GFLQLDEDMR KLYHDQQGGS 120

TAICVFVSPD KIYLVNCGDS RAVISRNGAA VISTIDHKPF SPKEQERIQN AGGSVMIKRI 180

NGTLAVSRAF GDYDFKNDGS KSPVDQMVSP EPDIIVCNRS EHDEFIVVAC DGIWDVMTSS 240

EVCEFIRSRL LVTYDLPMIV NSVLDICLHK GSRDNMTLLL LLLPGAPKVD MDAVKAERSL 300

DQTIVQITKE VIEKHEIHDF ETLIRLMKRM AINIPNLPPG GGLYAKYYII EQAFHEKFPD 360

TPAEIYDYFS M 371

Nucleotide Sequence
(FASTA)

ATGGGTCATA AAATGGGTGG CTTCTTGGAA AAACCAGAAA CTGAAAAGCA GGCTCAAGAG 60

GGTCATGGGA ATGGGCTGCG ATACTGCGTA AGTTCTATGC AAGGTTGGCG ATTGGAAATG 120

GAGGATAGCC ACTCGGCTGC TTGCCGGCTG AAGGATCCCT TCGCAACGTG GTCATATTTT 180

GCGGTGTTCG ATGGTCACGC TGGCAGTCAA ATATCACTGC ATTGCGCTGA ACATCTAATG 240

AGTACTATAT TGGAATCCGA ATCTTTTTCG AAGCACAAAT ACGAGGCTGG CATACGAGAG 300

GGCTTCCTGC AGTTGGATGA GGATATGAGG AAGCTGTATC ACGACCAGCA AGGCGGCTCG 360

ACGGCCATTT GTGTTTTTGT ATCACCGGAC AAAATATATC TGGTCAATTG TGGTGACTCG 420

CGTGCAGTGA TATCGCGAAA TGGAGCAGCT GTCATCAGTA CAATTGATCA CAAGCCGTTT 480

TCTCCCAAAG AACAAGAACG CATTCAAAAT GCCGGAGGCA GTGTAATGAT TAAAAGGATA 540

AATGGCACTC TGGCAGTTTC CCGGGCCTTC GGTGACTATG ATTTCAAGAA TGATGGCTCA 600

AAGTCTCCTG TCGATCAGAT GGTGTCTCCG GAACCTGATA TAATAGTTTG CAATCGGTCC 660

GAACACGATG AATTCATAGT TGTAGCCTGC GATGGCATTT GGGATGTGAT GACTAGCAGC 720

GAGGTTTGTG AATTTATTAG GTCACGGCTT TTGGTGACCT ATGACCTGCC GATGATTGTT 780

AACAGCGTAT TGGATATTTG CCTGCATAAA GGCAGCAGGG ACAATATGAC ACTGCTCCTC 840

CTACTTTTGC CTGGAGCACC AAAGGTCGAT ATGGATGCAG TTAAGGCCGA AAGGAGTCTT 900

GATCAAACTA TTGTGCAAAT AACCAAGGAA GTGATTGAGA AGCACGAAAT ACACGACTTT 960

GAAACACTTA TACGACTGAT GAAAAGAATG GCCATTAACA TTCCAAATCT ACCACCTGGC 1020

GGTGGTCTTT ATGCAAAATA TTACATTATA GAGCAAGCTT TCCACGAGAA ATTTCCAGAT 1080

ACTCCGGCTG AAATATATGA TTATTTTTCC ATGTAG 1116

Domain Profile

S: 3     vgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheila  62

         + v+s++g+r emed++++   +++ ++    +++f+v+DGh+gs+++  c+e+l + +

Q: 28    YCVSSMQGWRLEMEDSHSA---ACRLKDPFATWSYFAVFDGHAGSQISLHCAEHLMSTIL  84

         6789***********9976...5666666667*************************999

S: 63    eelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvanv  122

         e  +    ++ k ++ ++++Fl++de++    +k    ++ Gsta ++ ++++k+y  n+

Q: 85    ESES---FSKHKYEAGIREGFLQLDEDM----RKLYHDQQGGSTAICVFVSPDKIYLVNC  137

         9966...5799999**************....55566688********************

S: 123   GdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLavsRalGdly  182

         GdSrav++rng av  + dHkp +++E eRi++aggsv+ k   R++G LavsRa+Gd++

Q: 138   GDSRAVISRNGAAVISTIDHKPFSPKEQERIQNAGGSVMIK---RINGTLAVSRAFGDYD  194

         *****************************************...****************

S: 183   lk.........pyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

         +k         ++v+peP++ ++++++ def++ a+DG+wdv+++ e+++++r++l  +

Q: 195   FKndgskspvdQMVSPEPDIIVCNRSEHDEFIVVACDGIWDVMTSSEVCEFIRSRLLVTY  254

         ************************************************************

S: 234   aeqeaakkLvklalargskdnvsai  258

         ++  + +++++ +l++gs+dn++ +

Q: 255   DLPMIVNSVLDICLHKGSRDNMTLL  279

         **********************765

Domain Sequence
(FASTA)

YCVSSMQGWR LEMEDSHSAA CRLKDPFATW SYFAVFDGHA GSQISLHCAE HLMSTILESE 60

SFSKHKYEAG IREGFLQLDE DMRKLYHDQQ GGSTAICVFV SPDKIYLVNC GDSRAVISRN 120

GAAVISTIDH KPFSPKEQER IQNAGGSVMI KRINGTLAVS RAFGDYDFKN DGSKSPVDQM 180

VSPEPDIIVC NRSEHDEFIV VACDGIWDVM TSSEVCEFIR SRLLVTYDLP MIVNSVLDIC 240

LHKGSRDNMT LL 252

Keyword

Hydrolase; Magnesium; Metal-binding; Protein phosphatase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0000287	; F:magnesium ion binding
GO:0030145	; F:manganese ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR012911	; PP2C_C.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481	; PP2C; 1.
PF07830	; PP2C_C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013