EKS-DRM-00214

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DRM-00214

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/CK1	454.5	1.3E-136	21	284	264

Status

Unreviewed

Ensembl Protein

FBpp0082717

UniProt Accession

Q4AB31;

Protein Name

Protein Synonyms/Alias

Gilgamesh, isoform G;

Gene Name

gish

Gene Synonyms/Alias

gish; Dmel_CG6963;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
FBgn0250823	FBpp0099737	FBtr0100332
FBgn0250823	FBpp0082719	FBtr0083265
FBgn0250823	FBpp0082718	FBtr0083264
FBgn0250823	FBpp0099736	FBtr0100331
FBgn0250823	FBpp0099738	FBtr0100333
FBgn0250823	FBpp0082715	FBtr0083261
FBgn0250823	FBpp0082717	FBtr0083263
FBgn0250823	FBpp0082716	FBtr0083262
FBgn0250823	FBpp0303074	FBtr0330041
FBgn0250823	FBpp0293609	FBtr0305072
FBgn0250823	FBpp0293608	FBtr0305071
FBgn0250823	FBpp0290519	FBtr0301304

Organism

Drosophila melanogaster

Functional Description

Protein Length

422

Protein Sequence
(FASTA)

MYSTRQSVST TTGVLMVGPN FRVGKKIGCG NFGELRLGKN LYNNEHVAIK MEPMKSKAPQ 60

LHLEYRFYKL LGSHAEGVPE VYYFGPCGKY NALVMELLGP SLEDLFDICG RRFTLKSVLL 120

IAIQLLHRIE YVHSRHLIYR DVKPENFLIG RTSTKREKII HIIDFGLAKE YIDLDTNRHI 180

PYREHKSLTG TARYMSINTH MGREQSRRDD LEALGHMFMY FLRGSLPWQG LKADTLKERY 240

QKIGDTKRAT PIEVLCDGHP EEFATYLRYV RRLDFFETPD YDFLRRLFQD LFDRKGYTDE 300

GEFDWTGKTM STPVGSLQTG HEVIISPNKD RHNVTAKTNA KGGVAAWPDV PKPGATLGNL 360

TPADRHGSVQ VVSSTNGELN PDDPTAGHSN TPITQQPEVE VVDETKCCCF FKRKKKKSTR 420

QK 422

Nucleotide Sequence
(FASTA)

ATGTATTCCA CCCGCCAATC TGTAAGCACC ACGACCGGTG TACTTATGGT CGGACCAAAT 60

TTTCGTGTCG GTAAAAAAAT TGGCTGTGGT AATTTTGGCG AATTGCGTTT AGGCAAAAAC 120

CTTTACAACA ATGAACATGT AGCAATAAAA ATGGAGCCTA TGAAGTCAAA GGCTCCGCAA 180

CTACACTTAG AGTATAGGTT TTATAAACTA TTAGGATCAC ATGCAGAGGG TGTACCAGAA 240

GTATATTACT TCGGCCCATG CGGCAAATAC AATGCTCTTG TTATGGAGTT GCTTGGTCCA 300

TCACTTGAAG ATTTATTCGA TATTTGCGGC AGACGTTTCA CTTTGAAGAG CGTACTTCTG 360

ATAGCTATAC AATTACTCCA CCGGATCGAA TATGTTCATA GTCGGCACTT AATATATAGG 420

GATGTGAAAC CAGAGAACTT TCTCATTGGC AGAACGTCAA CAAAACGTGA AAAAATTATA 480

CATATAATTG ATTTCGGTTT GGCCAAAGAA TACATTGATT TAGATACAAA TAGGCATATA 540

CCATATCGGG AGCATAAATC CCTAACTGGA ACGGCACGTT ATATGTCAAT CAACACGCAC 600

ATGGGGCGTG AGCAGTCGCG ACGCGATGAT CTGGAGGCAT TGGGGCATAT GTTTATGTAT 660

TTCTTAAGGG GTTCACTGCC GTGGCAAGGC CTAAAGGCTG ATACACTCAA GGAGAGATAT 720

CAAAAAATCG GTGATACGAA ACGAGCAACG CCCATCGAGG TGCTTTGTGA TGGACATCCG 780

GAAGAGTTTG CGACATATTT GCGTTATGTA CGGCGGTTAG ATTTTTTCGA AACTCCCGAC 840

TATGATTTTC TGCGAAGACT GTTTCAAGAC TTATTCGATC GTAAGGGATA CACCGACGAG 900

GGCGAGTTCG ACTGGACAGG GAAGACAATG TCAACGCCCG TCGGATCTCT GCAAACTGGC 960

CATGAAGTCA TCATTTCACC AAATAAAGAT CGTCATAATG TTACGGCTAA GACAAATGCC 1020

AAAGGAGGTG TTGCTGCGTG GCCTGATGTG CCAAAGCCGG GGGCAACACT GGGCAATCTA 1080

ACGCCGGCCG ATCGGCATGG TTCAGTACAG GTTGTGAGTT CGACGAATGG CGAACTAAAT 1140

CCGGACGATC CCACGGCCGG ACACTCAAAC ACGCCCATCA CACAGCAGCC GGAAGTCGAA 1200

GTGGTCGATG AAACAAAATG TTGTTGTTTC TTTAAACGAA AGAAGAAGAA ATCGACGCGC 1260

CAAAAATGA 1269

Domain Profile

S: 1     yrvvkkiGsGsfGdiylgknlasgeevaikleskkskapqlklesrvykilqg.gvgiPe  59

         +rv+kkiG+G+fG+++lgknl+++e+vaik+e++kskapql+le+r+yk+l + ++g+Pe

Q: 21    FRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGShAEGVPE  80

         89*************************************************8769*****

S: 60    vryfgkekkynvlvldllGpsledlfdlcerkfslktvllladqlisrieyvhskeliyr  119

         v+yfg+++kyn+lv++llGpsledlfd+c r+f+lk+vll+a+ql++rieyvhs++liyr

Q: 81    VYYFGPCGKYNALVMELLGPSLEDLFDICGRRFTLKSVLLIAIQLLHRIEYVHSRHLIYR  140

         ************************************************************

S: 120   dikPdnfllgigrkgkk....vylidfGlakkyrdaktkkhipyreeksltGtaryasin  175

         d+kP+nfl+g  r+++k    +++idfGlak+y+d +t++hipyre+ksltGtary+sin

Q: 141   DVKPENFLIG--RTSTKrekiIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSIN  198

         ********66..444444457***************************************

S: 176   thlgkeqsrrddleslgyvllyflrgslPWqglkaatkkqkyekisekklstsievlceg  235

         th+g+eqsrrddle+lg++++yflrgslPWqglka+t k++y+ki+++k++t+ievlc+g

Q: 199   THMGREQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDG  258

         ************************************************************

S: 236   fPeefatylkyvrklkfeekPdyeyl  261

         +Peefatyl+yvr+l+f+e+Pdy++l

Q: 259   HPEEFATYLRYVRRLDFFETPDYDFL  284

         ***********************986

Domain Sequence
(FASTA)

FRVGKKIGCG NFGELRLGKN LYNNEHVAIK MEPMKSKAPQ LHLEYRFYKL LGSHAEGVPE 60

VYYFGPCGKY NALVMELLGP SLEDLFDICG RRFTLKSVLL IAIQLLHRIE YVHSRHLIYR 120

DVKPENFLIG RTSTKREKII HIIDFGLAKE YIDLDTNRHI PYREHKSLTG TARYMSINTH 180

MGREQSRRDD LEALGHMFMY FLRGSLPWQG LKADTLKERY QKIGDTKRAT PIEVLCDGHP 240

EEFATYLRYV RRLDFFETPD YDFL 264

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005886	; C:plasma membrane
GO:0070864	; C:sperm individualization complex
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0008347	; P:glial cell migration
GO:0051126	; P:negative regulation of actin nucleation
GO:0008355	; P:olfactory learning
GO:2001135	; P:regulation of endocytic recycling
GO:2000039	; P:regulation of trichome morphogenesis
GO:0007291	; P:sperm individualization
GO:0016055	; P:Wnt receptor signaling pathway

KEGG

dme:Dmel_CG6963

;

InterPros

IPR022247	; Casein_kinase-1_gamma_C.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF12605	; CK1gamma_C; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013