EKS-DRM-00106

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DRM-00106

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	485.1	8.2E-146	4	284	281

Status

Unreviewed

Ensembl Protein

FBpp0304023

UniProt Accession

Q9VL64;

Protein Name

Protein Synonyms/Alias

CG42366;

Gene Name

CG42366

Gene Synonyms/Alias

CG42366, Dmel_CG42366;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
FBgn0259712	FBpp0304023	FBtr0331633
FBgn0259712	FBpp0289242	FBtr0299965

Organism

Drosophila melanogaster

Functional Description

Protein Length

703

Protein Sequence
(FASTA)

MNRYITLTQL GDGTYGTVVL GQRKDTGEKV AIKRMKRKYY SWEEAMNLRE VKSLKKLSHP 60

NIVKLKEVIR ENDTLYFVFE YMKENLYQMI KDRDTHLPEP ELKSILFQVL TGLAFMHRHG 120

FFHRDLKPEN LLCSGPDLIK IADFGLAREI RSRPPFTDYV STRWYRAPEV LLHSTNYGST 180

IDLWAMGCIM AELYTFRPLF PGSSEVDQLF KICSVLGTPD KDDWPDGYRL ASMIHFRYPD 240

CIKVPLSSVV SRCSQNGLDL LEDMLAYDPD KRPTAQQSLK YPYFHALKRI SPTAATKANV 300

RLNSKYAASN GHPVQSVSNN VLPVQEKLQA VTELLHQTNN NMNSHSNLGK NNNLAPKNGG 360

VPRKYQPKLS FLTTSEMGAG SHADSSSLVG GATVDGVPVP QHQNGGESIN DIYLNRNISQ 420

LFGLPAGPQH QQQQQVHHPN VSFSTTSSRN AGAIYVNGSH LSYDTANMNA KNNAKFVVGA 480

SNGGYYVPVA RPSLLGPDAK VYNVFSKVSA SQAPPSLIVR QPQLQPEVAP APMRLSGRSR 540

AAAAVQDPKM GALKSDDLDL ILGSKLKTSA KRQRNAKANI LLEDLFGQLS MDSDSDGKYP 600

HTVPPTQQAK SGKTSTGGHG AGARERDLFG ESYLPRPGLR KKATQSSLEV NNGSHADSLA 660

PNAQKEKPAV ASSFPWDESN RTEDEKLTAW MVAENGSLLE NKF 703

Nucleotide Sequence
(FASTA)

ATGAACCGCT ATATCACGCT GACCCAACTG GGAGATGGAA CCTACGGCAC GGTGGTCCTC 60

GGCCAGCGCA AGGACACCGG CGAGAAGGTG GCCATCAAGC GCATGAAACG CAAGTACTAC 120

TCCTGGGAAG AGGCCATGAA TCTGCGCGAG GTTAAGTCCT TGAAAAAGTT GTCCCATCCG 180

AATATAGTCA AGCTGAAGGA GGTGATACGG GAGAACGATA CCCTGTACTT TGTGTTTGAG 240

TACATGAAGG AAAACCTCTA TCAGATGATA AAAGACCGAG ATACCCATTT ACCCGAACCG 300

GAACTCAAGA GTATTCTCTT CCAGGTCCTA ACTGGTCTGG CCTTCATGCA TCGTCATGGA 360

TTTTTCCACC GCGACCTGAA ACCGGAGAAC TTGCTCTGCT CCGGGCCGGA TCTCATCAAG 420

ATAGCTGATT TTGGCCTGGC CAGGGAGATC CGATCGAGGC CTCCGTTTAC GGACTACGTA 480

TCGACGCGTT GGTACCGCGC ACCGGAGGTA CTCCTGCACT CCACCAACTA CGGCAGTACC 540

ATCGACCTGT GGGCCATGGG CTGCATCATG GCCGAGCTCT ACACCTTTCG TCCGCTCTTC 600

CCGGGGAGTA GCGAGGTGGA TCAGCTCTTC AAGATCTGCT CTGTGCTGGG CACTCCAGAT 660

AAGGACGATT GGCCGGATGG TTATCGCCTG GCGAGCATGA TCCACTTTCG CTACCCGGAC 720

TGCATCAAAG TGCCACTGAG CAGCGTCGTC AGTCGCTGCA GCCAAAATGG TTTGGATCTG 780

CTGGAGGATA TGCTGGCCTA CGATCCTGAC AAGCGTCCGA CGGCGCAGCA GAGTCTGAAG 840

TATCCATACT TTCACGCACT CAAGCGGATA TCGCCCACGG CGGCCACCAA GGCGAATGTA 900

CGGCTGAACT CCAAGTATGC GGCATCCAAT GGGCATCCGG TACAGAGTGT CTCCAACAAC 960

GTGCTTCCGG TGCAGGAGAA GCTGCAGGCG GTCACAGAGT TGCTGCACCA AACCAACAAC 1020

AACATGAATA GCCACTCAAA TCTGGGCAAG AATAATAACC TGGCGCCAAA GAATGGCGGA 1080

GTGCCCAGAA AGTACCAACC GAAGTTGAGC TTCCTGACCA CCAGTGAGAT GGGCGCGGGT 1140

TCACATGCGG ACTCCTCCAG TCTGGTCGGT GGAGCCACAG TGGACGGAGT CCCGGTGCCA 1200

CAGCATCAGA ACGGCGGAGA GTCCATCAAC GACATCTACC TGAACCGCAA CATTTCGCAG 1260

CTCTTCGGAT TGCCAGCGGG TCCACAGCAC CAGCAACAGC AGCAGGTGCA CCATCCAAAT 1320

GTCTCCTTCA GCACCACCTC GTCCCGGAAT GCCGGCGCCA TCTACGTGAA TGGCAGTCAC 1380

CTCAGCTACG ACACGGCCAA CATGAATGCC AAGAACAATG CCAAGTTTGT GGTGGGCGCT 1440

TCCAATGGTG GCTACTACGT GCCCGTGGCC AGACCATCTC TCCTGGGCCC CGATGCCAAG 1500

GTCTACAACG TATTCTCCAA GGTCAGTGCC AGCCAGGCTC CGCCGAGTCT CATCGTGCGT 1560

CAGCCGCAAC TGCAACCGGA GGTGGCTCCG GCGCCCATGA GACTCTCGGG AAGATCGCGA 1620

GCGGCGGCGG CGGTCCAGGA TCCAAAGATG GGTGCTCTCA AGTCTGACGA TCTGGACCTT 1680

ATACTGGGTT CCAAGCTGAA AACCTCCGCC AAGCGACAGC GCAATGCCAA GGCCAACATT 1740

CTGCTGGAGG ATCTCTTCGG ACAGCTGTCC ATGGACTCGG ACAGCGACGG CAAGTATCCG 1800

CACACAGTGC CGCCCACGCA GCAGGCGAAA AGTGGGAAGA CGTCGACCGG TGGGCATGGC 1860

GCCGGCGCAC GGGAGCGGGA TCTCTTCGGG GAGAGTTATC TGCCCAGGCC GGGATTGCGG 1920

AAAAAGGCCA CACAGAGCAG TCTGGAGGTG AACAACGGCA GCCACGCGGA CTCGCTAGCT 1980

CCAAACGCAC AAAAGGAAAA GCCCGCTGTG GCGTCCAGTT TCCCGTGGGA TGAGTCCAAC 2040

AGGACGGAGG ACGAGAAGCT AACGGCTTGG ATGGTGGCCG AGAATGGATC GCTGCTGGAG 2100

AACAAATTCT GA 2112

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y ++++lGdGt+g+v+l+++++tge+vaik+mkrk++s+ee++nlrevkslkkl+ h+ni

Q: 4     YITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKLS-HPNI  62

         8899***************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         +klkevi  rend+ly+v+e+m+enlyq+ikdr+++l+e++lksil+q+l+glaf+h+hg

Q: 63    VKLKEVI--RENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrdlkPen+l++g++l+k+adfGlare+rs++P+tdyvstrwyraPevll+s++y s+

Q: 121   FFHRDLKPENLLCSGPDLIKIADFGLAREIRSRPPFTDYVSTRWYRAPEVLLHSTNYGST  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +dlwa+Gc++ae++++rplfPG+se+dq+fki++vlGtP+k++w+++y+las++++++p+

Q: 181   IDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHFRYPD  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++++l+++vs++s+++l+ll+d+laydPd+r+taqq+lkypyf

Q: 241   CIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YITLTQLGDG TYGTVVLGQR KDTGEKVAIK RMKRKYYSWE EAMNLREVKS LKKLSHPNIV 60

KLKEVIREND TLYFVFEYMK ENLYQMIKDR DTHLPEPELK SILFQVLTGL AFMHRHGFFH 120

RDLKPENLLC SGPDLIKIAD FGLAREIRSR PPFTDYVSTR WYRAPEVLLH STNYGSTIDL 180

WAMGCIMAEL YTFRPLFPGS SEVDQLFKIC SVLGTPDKDD WPDGYRLASM IHFRYPDCIK 240

VPLSSVVSRC SQNGLDLLED MLAYDPDKRP TAQQSLKYPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

dme:Dmel_CG42366

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013