EKS-DRM-00117

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DRM-00117

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	372.6	1.4E-111	46	307	262

Status

Unreviewed

Ensembl Protein

FBpp0073551

UniProt Accession

Q9U983;

Protein Name

Protein Synonyms/Alias

MAPKK;

Gene Name

lic

Gene Synonyms/Alias

lic; licorne; CG12244;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
FBgn0261524	FBpp0073551	FBtr0073720

Organism

Drosophila melanogaster

Functional Description

Protein Length

334

Protein Sequence
(FASTA)

MSKRHRLTPF TIAKEPEAAI VPPRNLDSRA TIQIGDRTFD IDADSLEKIC DLGRGAYGIV 60

DKMRHKQTDT VLAVKRIPMT VNIREQHRLV MDLDISMRSS DCPYTVHFYG AMYREGDVWI 120

CMEVMSTSLD KFYPKVFLHD LRMEESVLGK IAMSVVSALH YLHAQLKVIH RDVKPSNILI 180

NRAGQVKICD FGISGYLVDS IAKTIDAGCK PYMAPERIDP QGNPAQYDIR SDVWSLGIGM 240

IEMATGRYPY DNWRTPFEQL RQVVEDSPPR LPEGTFSPEF EDFIAVCLQK EYMARPNYEQ 300

LLKHSFIVEH LQRNTDISEF VARILDLPDA QPAQ 334

Nucleotide Sequence
(FASTA)

ATGTCCAAAC GCCACCGCCT CACGCCCTTT ACCATTGCCA AGGAGCCAGA GGCCGCCATA 60

GTCCCGCCAC GCAACCTGGA CTCGCGGGCC ACCATCCAAA TTGGCGACCG GACCTTTGAC 120

ATCGATGCAG ATAGTCTCGA GAAGATCTGC GATCTGGGCC GTGGCGCCTA TGGCATCGTG 180

GATAAGATGC GCCATAAGCA AACCGATACG GTCCTGGCCG TCAAACGCAT ACCCATGACC 240

GTAAATATTC GAGAACAGCA CCGCCTTGTA ATGGATTTGG ACATATCGAT GAGATCCAGC 300

GACTGCCCCT ACACCGTCCA CTTTTATGGT GCGATGTATC GCGAGGGCGA TGTCTGGATT 360

TGCATGGAGG TGATGAGCAC CAGCCTGGAC AAGTTCTATC CGAAGGTCTT CCTTCACGAT 420

CTGCGAATGG AGGAAAGCGT GCTGGGCAAG ATTGCCATGA GCGTGGTCAG TGCGCTGCAC 480

TATCTGCACG CTCAACTGAA AGTCATTCAT CGGGACGTCA AGCCCTCGAA CATACTGATC 540

AATCGGGCCG GCCAGGTCAA GATCTGTGAC TTTGGCATCT CAGGCTACCT CGTCGACTCC 600

ATTGCCAAAA CCATTGATGC CGGTTGCAAG CCGTACATGG CGCCGGAACG GATCGATCCC 660

CAAGGAAATC CGGCGCAATA CGACATCAGG TCGGATGTTT GGTCGCTGGG CATCGGCATG 720

ATCGAAATGG CCACGGGCCG CTACCCATAC GACAATTGGC GAACGCCATT TGAGCAACTG 780

CGTCAGGTGG TTGAGGACAG TCCGCCGCGC CTGCCGGAGG GAACATTTTC GCCGGAATTC 840

GAGGACTTCA TCGCCGTCTG CCTGCAGAAG GAGTATATGG CAAGGCCCAA CTACGAGCAG 900

CTGCTCAAGC ACAGCTTCAT CGTGGAGCAC CTGCAGCGCA ACACGGACAT CTCGGAGTTC 960

GTGGCCAGGA TACTGGATCT GCCCGACGCG CAGCCGGCGC AGTAG 1005

Domain Profile

S: 1     lekleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyi  60

         lek+ +lG+G++g+V k++hk+++++lavK+i ++++ +eq++++++l++ ++ss++py+

Q: 46    LEKICDLGRGAYGIVDKMRHKQTDTVLAVKRIPMTVNIREQHRLVMDLDISMRSSDCPYT  105

         78999*******************************************************

S: 61    vkfyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylke  120

         v+fyGa+++egdv+icme+m+ tsldk++ kv+ ++ r++e+vlgkia++vv+al+yl+

Q: 106   VHFYGAMYREGDVWICMEVMS-TSLDKFYPKVFLHDLRMEESVLGKIAMSVVSALHYLHA  164

         *********************.**************************************

S: 121   klkiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksa.vGtksYmaPErieg...k  176

         +lk+iHRDvKPsNiL+n++G+vK+CDFG+sg+lvdsiAk++ +G+k+YmaPEri++

Q: 165   QLKVIHRDVKPSNILINRAGQVKICDFGISGYLVDSIAKTIdAGCKPYMAPERIDPqgnP  224

         *******************************************************98888

S: 177   kkYsvksdvWslGltlvelatgrypyeklkeilellkaivneeppklpeeefseefqefv  236

         ++Y+++sdvWslG+ ++e+atgrypy+++++++e+l+++v+++pp+lpe +fs+ef++f+

Q: 225   AQYDIRSDVWSLGIGMIEMATGRYPYDNWRTPFEQLRQVVEDSPPRLPEGTFSPEFEDFI  284

         9***********************************************************

S: 237   skClkkdekeRpklkellkhafi  259

         + Cl+k+   Rp++++llkh+fi

Q: 285   AVCLQKEYMARPNYEQLLKHSFI  307

         **********************7

Domain Sequence
(FASTA)

LEKICDLGRG AYGIVDKMRH KQTDTVLAVK RIPMTVNIRE QHRLVMDLDI SMRSSDCPYT 60

VHFYGAMYRE GDVWICMEVM STSLDKFYPK VFLHDLRMEE SVLGKIAMSV VSALHYLHAQ 120

LKVIHRDVKP SNILINRAGQ VKICDFGISG YLVDSIAKTI DAGCKPYMAP ERIDPQGNPA 180

QYDIRSDVWS LGIGMIEMAT GRYPYDNWRT PFEQLRQVVE DSPPRLPEGT FSPEFEDFIA 240

VCLQKEYMAR PNYEQLLKHS FI 262

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004708	; F:MAP kinase kinase activity
GO:0004702	; F:receptor signaling protein serine/threonine kinase activity
GO:0002385	; P:mucosal immune response
GO:0007314	; P:oocyte anterior/posterior axis specification
GO:0045793	; P:positive regulation of cell size
GO:0040018	; P:positive regulation of multicellular organism growth
GO:0048082	; P:regulation of adult chitin-containing cuticle pigmentation

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013