EKS-ZEM-00449

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ZEM-00449

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/IRAK	199.2	5.3E-58	435	706	272

Status

Unreviewed

Ensembl Protein

GRMZM2G153393_P01

UniProt Accession

O81105;

Protein Name

Protein Synonyms/Alias

Leucine-rich repeat transmembrane protein kinase 1;

Gene Name

ltk1

Gene Synonyms/Alias

ltk1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
GRMZM2G153393	GRMZM2G153393_P01	GRMZM2G153393_T01
GRMZM2G153393	GRMZM2G153393_P02	GRMZM2G153393_T02

Organism

Zea mays

Functional Description

Protein Length

736

Protein Sequence
(FASTA)

MARRRMRRGG GGGGGGGGGV VDVVRVRRLL LLSLTCCSSI WPGGRIFAAA DTDPNDLNVL 60

NTLFTSLNSP GQLTGWQANG GDPCGQSWKG ITCSGSGVTK IQLPNLSLTG NLAYNMNNLG 120

SLVELDMSQN NLGGGGQIQY NLPNMKLEKL NLAGNQFGGN LPYSISTMPN LKYLNLNHNQ 180

LQGNISDVFS NLYSLSELDL SFNSLTGDLP QSFTGLSSLK KVYLQNNQFT GNINVLANLP 240

LETLNVANNH FTGWIPSQLK KINSLQTDGN SWSTGPAPPP PPYTAPPPPP NHWNADGSSS 300

SSSSGGRSGI GGGGVAGIII SLLVVGSVVA FLVIKRRKRK AAMKEHFEQH QPFTSFPSNE 360

VKDMKPVYEA TTVDIESLAS PASVNLKPPP KIERNKSFDD DDDFSNKLVA KKSNITPINA 420

TVYSVADLQM ATDSFSFDNL VGEGTFGRVY RAQFNDGKVL AIKKLDSTVM PFQSSDDFAE 480

LVSNISKLHH PNLNELVGYC MEHGQHLLVY DFHRNGSLHD LLHLSDEYSK PLSWNTRIKI 540

ALGSARALEY LHEICSPSII HKNFKSSNIL LDSEFNPHLS DAGLASFIPD AEFQAAEQSA 600

GYTAPEVDMT GQYTLKSDVY SFGVVMLELL TGRRPFDSSR PRSEQSLVRW ATPQLHDIDA 660

LDRMVDPALK GLYPAKSLSR FADVLALCVQ PEPEFRPPMS EVVQALVRLV QRANMTKRML 720

DGDTSRRPDD LDQDFI 736

Nucleotide Sequence
(FASTA)

ATGGCGAGGA GGAGGATGAG GAGGGGAGGC GGTGGCGGTG GCGGTGGCGG TGGCGGGGTG 60

GTGGATGTGG TGCGGGTGCG GCGGCTGCTG CTGCTGTCCC TGACCTGCTG CAGCAGCATT 120

TGGCCAGGCG GACGGATCTT CGCTGCTGCG GACACTGACC CCAACGATCT TAACGTCCTC 180

AACACGCTCT TCACCAGTCT GAATTCTCCT GGGCAGCTCA CAGGTTGGCA GGCGAATGGG 240

GGTGATCCTT GTGGCCAGTC ATGGAAGGGC ATTACTTGCT CAGGATCAGG GGTCACTAAA 300

ATCCAATTAC CAAACTTGTC ACTCACTGGA AATTTGGCCT ACAACATGAA TAACTTGGGT 360

TCATTAGTTG AGCTTGACAT GAGCCAAAAT AACCTTGGCG GTGGAGGTCA AATACAGTAC 420

AATCTTCCCA ATATGAAGCT TGAGAAACTC AATCTTGCAG GAAATCAATT TGGTGGAAAT 480

TTACCCTACT CAATTTCGAC GATGCCTAAT CTTAAGTATT TAAACCTTAA TCATAACCAA 540

CTACAAGGAA ACATCAGTGA TGTATTTTCC AACCTTTACA GTTTGTCAGA ACTGGATCTG 600

TCCTTTAATT CCCTTACTGG TGATCTACCA CAAAGTTTCA CTGGATTGTC AAGCCTGAAA 660

AAAGTGTATT TGCAGAACAA CCAATTTACT GGTAATATCA ATGTCTTAGC CAATCTCCCC 720

CTTGAAACTT TGAATGTTGC GAACAACCAT TTCACTGGTT GGATTCCTAG TCAGCTTAAG 780

AAGATAAACA GTCTACAGAC TGATGGAAAT TCTTGGAGCA CAGGACCAGC GCCACCTCCA 840

CCTCCATACA CAGCGCCGCC TCCTCCTCCA AACCATTGGA ATGCTGATGG TTCATCAAGT 900

TCATCAAGTT CTGGTGGAAG ATCTGGGATA GGTGGTGGAG GTGTAGCAGG AATCATTATA 960

TCGTTGCTGG TTGTTGGATC AGTTGTTGCA TTTCTTGTGA TCAAAAGAAG AAAACGCAAA 1020

GCTGCTATGA AAGAACATTT TGAACAGCAC CAGCCATTCA CTTCCTTCCC TTCAAATGAA 1080

GTTAAAGACA TGAAGCCTGT CTACGAGGCC ACCACAGTAG ACATAGAGTC TTTGGCTTCA 1140

CCTGCTTCAG TTAATCTGAA ACCACCTCCG AAGATAGAAC GAAACAAATC ATTTGATGAT 1200

GACGATGATT TTTCAAACAA GCTTGTTGCA AAGAAAAGTA ATATAACACC TATAAATGCA 1260

ACTGTTTATT CAGTTGCAGA TCTACAGATG GCAACAGATA GCTTTAGCTT CGACAACCTT 1320

GTTGGAGAGG GTACTTTTGG ACGTGTTTAC AGGGCACAAT TCAATGATGG AAAGGTTCTG 1380

GCGATCAAGA AATTAGATAG TACTGTGATG CCATTTCAAT CATCTGATGA CTTTGCTGAA 1440

CTGGTCTCGA ACATTTCAAA ATTGCACCAT CCGAATCTGA ATGAGCTTGT GGGCTATTGC 1500

ATGGAACATG GCCAGCACTT GCTTGTGTAT GATTTCCACA GGAATGGATC ACTTCATGAT 1560

CTACTCCACC TTTCAGATGA GTACAGCAAG CCACTTAGCT GGAACACTCG TATCAAGATC 1620

GCACTCGGCT CTGCCCGTGC ACTGGAGTAC CTTCATGAAA TATGTTCTCC ATCCATCATC 1680

CATAAGAATT TCAAGTCGTC AAACATTTTG CTGGACTCAG AATTCAATCC ACACCTTTCA 1740

GATGCTGGAC TTGCAAGCTT TATTCCTGAT GCTGAATTCC AGGCAGCAGA ACAAAGTGCC 1800

GGATACACTG CCCCAGAAGT GGACATGACC GGTCAGTACA CCCTCAAGAG TGATGTCTAC 1860

AGCTTTGGAG TTGTCATGCT TGAACTATTG ACAGGACGTA GACCATTTGA CAGCTCTAGA 1920

CCCAGGTCAG AGCAGTCACT TGTGCGGTGG GCAACACCCC AGCTGCATGA CATCGACGCA 1980

TTGGACAGGA TGGTCGATCC TGCACTCAAG GGTCTATACC CAGCCAAATC TCTATCCCGA 2040

TTTGCTGATG TCCTTGCCCT GTGTGTCCAG CCTGAACCAG AATTCAGGCC ACCAATGTCA 2100

GAGGTGGTGC AAGCATTGGT TCGACTTGTG CAGAGGGCCA ACATGACGAA GAGGATGCTT 2160

GATGGGGATA CTTCTCGGCG ACCAGATGAC CTGGACCAAG ATTTCATATG A 2211

Domain Profile

S: 1     fsednrigeGgfgevyrgelknt.avavkklkeeadlslkelkqsfltElkvlarfrHdn  59

         fs dn +geG+fg vyr+++++  ++a+kkl +++   + +++  f + +  +++++H+n

Q: 435   FSFDNLVGEGTFGRVYRAQFNDGkVLAIKKLDSTVM--PFQSSDDFAELVSNISKLHHPN  492

         67799**************9975389*****98764..5566788988899*********

S: 60    ilellgysaeseklcLvYqymknGsLedrLqcq.kgsepLsWpqRlsillGtaraiefLH  118

         + el+gy++e++++ LvY + +nGsL+d L+   + s+pLsW++R++i+lG ara+e+LH

Q: 493   LNELVGYCMEHGQHLLVYDFHRNGSLHDLLHLSdEYSKPLSWNTRIKIALGSARALEYLH  552

         *******************************996779***********************

S: 119   easp.slihgdiksaNiLLDekltpKlgDfglarfapesekqsstvlrtskvrgtlaYlp  177

         e  + s+ih++ ks+NiLLD +++p l+D gla f p++e q+         ++++ Y +

Q: 553   EICSpSIIHKNFKSSNILLDSEFNPHLSDAGLASFIPDAEFQA--------AEQSAGYTA  604

         *9777*****************************999988665........456789***

S: 178   eefirvgqltvkvDvySfGiVllEvltGlravded..rktkyLkdllkeeieeekveile  235

         +e   +gq t k+DvySfG+V+lE+ltG+r  d +  r+++ L+     ++  ++++ l+

Q: 605   PEVDMTGQYTLKSDVYSFGVVMLELLTGRRPFDSSrpRSEQSLVRWATPQL--HDIDALD  662

         ******************************976651145555555544444..56789**

S: 236   kfldkkagkl.eeellealielalaclaekakkrPtmsqvlell  278

         + +d     l + ++l+ ++ + + c++ + + rP+ms+v++ l

Q: 663   RMVDPALKGLyPAKSLSRFADVLALCVQPEPEFRPPMSEVVQAL  706

         ****98766559999999**********************9976

Domain Sequence
(FASTA)

FSFDNLVGEG TFGRVYRAQF NDGKVLAIKK LDSTVMPFQS SDDFAELVSN ISKLHHPNLN 60

ELVGYCMEHG QHLLVYDFHR NGSLHDLLHL SDEYSKPLSW NTRIKIALGS ARALEYLHEI 120

CSPSIIHKNF KSSNILLDSE FNPHLSDAGL ASFIPDAEFQ AAEQSAGYTA PEVDMTGQYT 180

LKSDVYSFGV VMLELLTGRR PFDSSRPRSE QSLVRWATPQ LHDIDALDRM VDPALKGLYP 240

AKSLSRFADV LALCVQPEPE FRPPMSEVVQ AL 272

Keyword

Kinase; Leucine-rich repeat; Membrane; Repeat; Transferase; Transmembrane.

Sequence Source

Ensembl

Orthology

Ortholog group

Arabidopsis thaliana"; ?>Brachypodium distachyon"; ?>Brassica rapa"; ?>Oryza brachyantha"; ?>Oryza glaberrima"; ?>Oryza indica"; ?>Oryza sativa"; ?>Populus trichocarpa"; ?>Solanum lycopersicum"; ?>Solanum tuberosum"; ?>Sorghum bicolor"; ?>

Gene Ontology

GO:0005829	; C:cytosol
GO:0016021	; C:integral to membrane
GO:0005634	; C:nucleus
GO:0005886	; C:plasma membrane
GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity

KEGG

dosa:Os03t0183800-01

;

InterPros

IPR011009	; Kinase-like_dom.
IPR001611	; Leu-rich_rpt.
IPR013210	; LRR-contain_N2.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.

Pfam

PF00560	; LRR_1; 1.
PF08263	; LRRNT_2; 1.
PF07714	; Pkinase_Tyr; 1.

SMARTs

Prosites

PS51450	; LRR; 6.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013