| Tag | Content |
|---|
| EKPD ID | EKS-ORS-00786 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| CMGC/CDK | 356.5 | 3.2E-106 | 19 | 299 | 281 |
|
| Status | Reviewed |
| Ensembl Protein | LOC_Os05g32600.1 |
| UniProt Accession | P29620; Q0DIF9; Q60ES0; |
| Protein Name | Cyclin-dependent kinase D-1 |
| Protein Synonyms/Alias | CDKD; CDC2+/CDC28-related protein kinase R2; CDK-activating kinase R2; CAK-R2; |
| Gene Name | CDKD-1 |
| Gene Synonyms/Alias | CDKD-1; R2; Os05g0392300, LOC_Os05g32600; OJ1764_D01.12; |
| Ensembl Information | |
| Organism | Oryza sativa |
| Functional Description | CDK-activating kinase that may control G1/S phaseprogression. May control the rate of cell differentiation to accomplish proper development of organs, or in response to a changing environment. Forms a complex with cyclin CYCH1-1 that phosphorylates CDKA-1 and the C-terminal domain (CTD) of the large subunit of RNA polymerase II. |
| Protein Length | 424 |
Protein Sequence
(FASTA) | | MASGDGGDDA GVKRVADRYL KREVLGEGTY GVVFKAVDTK TGNTVAIKKI RLGKYKEGVN 60 | | FTALREIKLL KELKDSNIIE LIDAFPYKGN LHLVFEFMET DLEAVIRDRN IVLSPADTKS 120 | | YIQMMLKGLA FCHKKWVLHR DMKPNNLLIG ADGQLKLADF GLARIFGSPE RNFTHQVFAR 180 | | WYRAPELLFG TKQYGSAVDI WAAGCIFAEL LLRRPFLQGS SDIDQLGKIF AAFGTPKSSQ 240 | | WPDMVYLPDY VEYQFVSAPP LRSLFPMASD DALDLLSRMF TYDPKARITA QQALEHRYFL 300 | | SVPAPTKPSQ LPRPPPKGDS GNNKIPDLNL QDGPVVLSPP RKLRRVTAHE GMEVHMHRAD 360 | | RTEEHPSGAR HMDDMSSQSS RIPMSVDVGA IFGTRPAPRP TLNSADKSRL KRKLDMDPEF 420 | | GYTE 424 |
|
Nucleotide Sequence
(FASTA) | | ATGGCGAGCG GCGACGGCGG CGACGACGCG GGCGTGAAGC GCGTGGCGGA CCGCTACCTG 60 | | AAGCGCGAGG TCCTGGGAGA GGGAACCTAC GGCGTCGTCT TCAAGGCCGT CGACACCAAG 120 | | ACTGGGAATA CAGTCGCAAT AAAGAAAATC CGGCTAGGGA AGTACAAGGA AGGTGTCAAT 180 | | TTCACTGCAT TGAGGGAAAT TAAACTTCTT AAGGAGCTGA AAGATTCTAA TATTATAGAG 240 | | CTGATTGATG CTTTCCCTTA CAAGGGAAAC TTACATCTTG TATTTGAGTT CATGGAGACT 300 | | GATTTGGAAG CTGTCATACG AGATAGGAAC ATTGTATTAT CTCCAGCTGA TACAAAATCT 360 | | TATATTCAGA TGATGTTAAA AGGTTTAGCC TTCTGCCATA AGAAATGGGT GCTACACAGG 420 | | GATATGAAAC CAAATAATTT ACTCATTGGC GCTGATGGGC AGCTTAAGCT TGCTGACTTT 480 | | GGTCTGGCGC GCATATTTGG GAGTCCAGAG CGGAACTTCA CTCATCAGGT CTTTGCACGA 540 | | TGGTACCGAG CACCAGAATT ATTATTTGGC ACCAAGCAGT ATGGATCTGC AGTTGATATT 600 | | TGGGCTGCTG GTTGTATTTT TGCTGAACTG CTGCTTAGGC GACCGTTTCT CCAGGGTTCT 660 | | AGTGACATTG ATCAACTTGG GAAGATCTTT GCTGCATTTG GAACTCCAAA GTCTTCTCAA 720 | | TGGCCGGACA TGGTTTATCT TCCAGATTAT GTTGAATACC AATTTGTCTC TGCACCTCCA 780 | | CTTCGCTCAT TGTTTCCAAT GGCCAGTGAT GATGCATTGG ATCTTCTATC AAGAATGTTT 840 | | ACATATGATC CAAAAGCAAG AATTACAGCT CAGCAGGCTC TAGAACACCG GTACTTTTTA 900 | | TCAGTACCAG CGCCAACAAA ACCATCACAG CTTCCAAGGC CACCACCTAA GGGTGATTCA 960 | | GGGAATAACA AGATACCAGA CTTGAACCTG CAGGACGGCC CTGTTGTTCT GTCCCCGCCA 1020 | | AGAAAGTTGC GCAGGGTGAC TGCCCATGAA GGGATGGAAG TCCATATGCA TCGGGCGGAT 1080 | | AGAACAGAAG AGCATCCTTC AGGGGCAAGG CACATGGATG ACATGTCCAG CCAGAGTTCT 1140 | | AGAATACCAA TGTCAGTTGA TGTTGGAGCT ATTTTTGGGA CACGACCTGC TCCTAGACCA 1200 | | ACGTTAAACA GTGCCGACAA GTCTCGTTTA AAACGGAAAC TTGATATGGA TCCAGAATTT 1260 | | GGATACACAG AGTAA 1275 |
|
| Domain Profile | S: 1 yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni 60 | y k e +geGtyg+v+ka d++tg++vA+Kkirl k kegv++talrEi+llkelk +ni | Q: 19 YLKREVLGEGTYGVVFKAVDTKTGNTVAIKKIRLGKYKEGVNFTALREIKLLKELKDSNI 78 | 5677899***************************************************** |
| S: 61 vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk 120 | ++L++ + k +l+Lvfef+e+dL+ ++++ ++ ls+++ ks+++++l+gla++H+++ | Q: 79 IELIDAFP-YKGNLHLVFEFMETDLEAVIRDRNI-VLSPADTKSYIQMMLKGLAFCHKKW 136 | ********.99***********************.************************* |
| S: 121 ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst 180 | +lHRD+Kp+NlLi ++g+lklaDfGlar f+sp++++t++v +wYraPelL+g+k+Y++ | Q: 137 VLHRDMKPNNLLIGADGQLKLADFGLARIFGSPERNFTHQVFARWYRAPELLFGTKQYGS 196 | ************************************************************ |
| S: 181 avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeykksfpk 240 | avDiW++gci+aell r+p++qg+s+idql +if+ +gtp++++wp++ lp+y +++ | Q: 197 AVDIWAAGCIFAELLLRRPFLQGSSDIDQLGKIFAAFGTPKSSQWPDMVYLPDYV-EYQF 255 | ******************************************************9.5555 |
| S: 241 kkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf 284 | ++ l++ ++ ++++aldll++++++dpk Ri+a++al+h+yf | Q: 256 VSAPPLRSLFPMASDDALDLLSRMFTYDPKARITAQQALEHRYF 299 | 56789**************************************9 |
|
Domain Sequence
(FASTA) | | YLKREVLGEG TYGVVFKAVD TKTGNTVAIK KIRLGKYKEG VNFTALREIK LLKELKDSNI 60 | | IELIDAFPYK GNLHLVFEFM ETDLEAVIRD RNIVLSPADT KSYIQMMLKG LAFCHKKWVL 120 | | HRDMKPNNLL IGADGQLKLA DFGLARIFGS PERNFTHQVF ARWYRAPELL FGTKQYGSAV 180 | | DIWAAGCIFA ELLLRRPFLQ GSSDIDQLGK IFAAFGTPKS SQWPDMVYLP DYVEYQFVSA 240 | | PPLRSLFPMA SDDALDLLSR MFTYDPKARI TAQQALEHRY F 281 |
|
| Keyword | ATP-binding; Cell cycle; Cell division; Complete proteome; Kinase; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |