EKS-ORS-00643

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORS-00643

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	320.5	2.3E-95	13	268	256

Status

Reviewed

Ensembl Protein

LOC_Os07g05620.2

UniProt Accession

Q6ZLP5;

Protein Name

CBL-interacting protein kinase 23

Protein Synonyms/Alias

OsCIPK23;

Gene Name

CIPK23

Gene Synonyms/Alias

CIPK23; Os07g0150700, LOC_Os07g05620; OJ1027_G06.32;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
LOC_Os07g05620	LOC_Os07g05620.1	LOC_Os07g05620.1
LOC_Os07g05620	LOC_Os07g05620.2	LOC_Os07g05620.2

Organism

Oryza sativa

Functional Description

CIPK serine-threonine protein kinases interact with CBLproteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium- dependent manner (By similarity).

Protein Length

449

Protein Sequence
(FASTA)

MSVSGGRTRV GRYELGRTLG EGTFAKVKFA RNADSGENVA IKILDKDKVL KHKMIAQIKR 60

EISTMKLIRH PNVIRMHEVM ASKTKIYIVM ELVTGGELFD KIASRGRLKE DDARKYFQQL 120

INAVDYCHSR GVYHRDLKPE NLLLDASGTL KVSDFGLSAL SQQVREDGLL HTTCGTPNYV 180

APEVINNKGY DGAKADLWSC GVILFVLMAG YLPFEDSNLM SLYKKIFKAD FSCPSWFSTS 240

AKKLIKKILD PNPSTRITIA ELINNEWFKK GYQPPRFETA DVNLDDINSI FNESGDQTQL 300

VVERREERPS VMNAFELIST SQGLNLGTLF EKQSGSVKRE TRFASRLPAN EILSKIEAAA 360

GPMGFNVQKR NYKLKLQGEN PGRKGQLAIA TEVFEVTPSL YMVELRKSNG DTLEFHKFYH 420

NISNGLKDVM WKPESSIIAG DEIQHRRSP 449

Nucleotide Sequence
(FASTA)

ATGAGCGTGT CGGGCGGGAG GACGCGGGTG GGGAGGTACG AGCTCGGGAG GACGCTCGGC 60

GAGGGCACCT TCGCCAAGGT CAAGTTCGCC CGCAACGCGG ACTCCGGCGA GAATGTCGCC 120

ATCAAGATCC TCGACAAGGA CAAGGTCCTC AAGCACAAGA TGATCGCCCA GATAAAGCGC 180

GAGATCTCCA CCATGAAGCT CATCAGGCAC CCCAACGTCA TCCGGATGCA TGAGGTGATG 240

GCCAGCAAGA CCAAAATATA CATAGTGATG GAGCTTGTCA CCGGTGGTGA ACTTTTCGAC 300

AAGATTGCTT CGCGTGGGAG GCTGAAAGAG GATGATGCAA GGAAGTATTT TCAGCAGCTG 360

ATCAACGCTG TCGATTACTG TCATAGCAGA GGAGTCTATC ACCGGGATCT CAAGCCCGAA 420

AATCTTCTGC TTGATGCTAG TGGCACTCTC AAAGTATCAG ATTTTGGGCT GAGTGCACTG 480

TCTCAACAAG TCAGAGAGGA TGGTCTGTTG CACACTACCT GTGGAACTCC TAATTATGTT 540

GCTCCCGAGG TTATCAACAA CAAAGGATAT GATGGAGCCA AGGCTGATCT GTGGTCATGT 600

GGAGTGATTC TCTTTGTCCT CATGGCAGGC TACCTTCCAT TTGAAGACTC AAACCTCATG 660

TCACTTTACA AGAAGATCTT CAAAGCAGAC TTCAGTTGCC CGTCTTGGTT CTCTACAAGT 720

GCGAAGAAGC TCATCAAGAA AATACTAGAT CCTAATCCTA GCACCAGGAT TACCATCGCA 780

GAGCTTATCA ACAATGAGTG GTTCAAGAAG GGATATCAGC CTCCAAGGTT TGAGACAGCA 840

GATGTTAACC TGGATGATAT CAACTCTATT TTTAATGAAT CTGGGGACCA AACACAGCTT 900

GTTGTCGAGA GGCGAGAAGA GAGGCCATCA GTGATGAATG CTTTTGAGTT GATCTCTACA 960

TCTCAGGGTC TCAATCTTGG CACACTCTTT GAAAAGCAAT CGGGTTCTGT GAAGCGAGAA 1020

ACAAGATTTG CATCAAGGCT GCCTGCAAAC GAGATATTGT CGAAAATTGA AGCAGCTGCT 1080

GGACCCATGG GCTTTAATGT ACAGAAGCGC AACTACAAGC TGAAGTTGCA AGGAGAGAAT 1140

CCAGGAAGGA AAGGTCAGCT TGCAATTGCA ACAGAGGTTT TTGAAGTCAC GCCCTCGCTG 1200

TACATGGTTG AGCTCCGCAA ATCTAACGGC GACACTCTTG AATTCCATAA GTTCTACCAC 1260

AACATCTCCA ATGGCCTGAA AGATGTGATG TGGAAGCCGG AGAGTAGCAT AATCGCAGGC 1320

GATGAGATCC AGCATCGGAG GTCACCGTGA 1350

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y+l++tlGeg+f+kVk a++ + +e+va+Ki++k+k+ +++ + +ikrEi+++k ++hpn

Q: 13    YELGRTLGEGTFAKVKFARNADSGENVAIKILDKDKVlKHKMIAQIKREISTMKLIRHPN  72

         99********************************9987889999****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         +i+++ev+ +k+k+y+v+e+++ggeLfd+i ++grlke++ark+f+ql++av+Y+hs+g+

Q: 73    VIRMHEVMASKTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGV  132

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlan...lfkegklletfcGsppYaaPellkgkkYeg  176

          HrDlKpeNllld+++++k++DFGl++   +++e+ ll+t+cG+p+Y+aPe++++k Y+g

Q: 133   YHRDLKPENLLLDASGTLKVSDFGLSAlsqQVREDGLLHTTCGTPNYVAPEVINNKGYDG  192

         ************************99866577888*************************

S: 177   pkvDvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvd  236

          k+D+Ws+Gv+L++l++g lPf+++nl +l++ki k ++++p++ s+++++L++k+L  +

Q: 193   AKADLWSCGVILFVLMAGYLPFEDSNLMSLYKKIFKADFSCPSWFSTSAKKLIKKILDPN  252

         ************************************************************

S: 237   pekRatieeilkhewl  252

         p++R+ti e+ ++ew+

Q: 253   PSTRITIAELINNEWF  268

         ***************6

Domain Sequence
(FASTA)

YELGRTLGEG TFAKVKFARN ADSGENVAIK ILDKDKVLKH KMIAQIKREI STMKLIRHPN 60

VIRMHEVMAS KTKIYIVMEL VTGGELFDKI ASRGRLKEDD ARKYFQQLIN AVDYCHSRGV 120

YHRDLKPENL LLDASGTLKV SDFGLSALSQ QVREDGLLHT TCGTPNYVAP EVINNKGYDG 180

AKADLWSCGV ILFVLMAGYL PFEDSNLMSL YKKIFKADFS CPSWFSTSAK KLIKKILDPN 240

PSTRITIAEL INNEWF 256

Keyword

Alternative splicing; ATP-binding; Complete proteome; Kinase; Manganese; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Arabidopsis thaliana"; ?>Brachypodium distachyon"; ?>Brassica rapa"; ?>Glycine max"; ?>Hordeum vulgare"; ?>Musa acuminata"; ?>Oryza brachyantha"; ?>Oryza glaberrima"; ?>Oryza indica"; ?>Physcomitrella patens"; ?>Populus trichocarpa"; ?>Selaginella moellendorffii"; ?>Setaria italica"; ?>Solanum lycopersicum"; ?>Solanum tuberosum"; ?>Sorghum bicolor"; ?>Vitis vinifera"; ?>Zea mays"; ?>

Gene Ontology

GO:0005829	; C:cytosol
GO:0005634	; C:nucleus
GO:0005886	; C:plasma membrane
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0010107	; P:potassium ion import
GO:0007584	; P:response to nutrient
GO:0009414	; P:response to water deprivation
GO:0007165	; P:signal transduction
GO:0010118	; P:stomatal movement

KEGG

dosa:Os07t0150700-01	;
osa:4342410	;

InterPros

IPR011009	; Kinase-like_dom.
IPR018451	; NAF/FISL_domain.
IPR004041	; NAF_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF03822	; NAF; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50816	; NAF; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013