EKS-SOT-00238

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SOT-00238

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/IRAK	220.2	1.0E-64	887	1157	271

Status

Unreviewed

Ensembl Protein

PGSC0003DMT400050728

UniProt Accession

A4LAP6;

Protein Name

Protein Synonyms/Alias

BRI1 protein;

Gene Name

BRI1

Gene Synonyms/Alias

BRI1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
PGSC0003DMG400019698	PGSC0003DMT400050728	PGSC0003DMT400050728

Organism

Solanum tuberosum

Functional Description

Protein Length

1206

Protein Sequence
(FASTA)

MKAHKTVFYQ HPLSLNKLFF VLLLIFFLPP ASPASVNGLF KDSQQLLSFK AALPPTPTLL 60

QNWLPSTDPC SFTGVSCKNS RVSSIDLSNT FLSVDFSLVT SYLLPLSNLE SLVLKNANLS 120

GSLTSAAKSQ CGVSLDSIDL AENTISGPIS DISSFGVCSN LKSLNLSKNF LDPPGKEILK 180

GATFSLQVLD LSYNNISGFN LFPWVSSMGF GELEFFSLKG NKLAGSIPEL DFKNLSHLDL 240

SANNFSTVFP SFKDCSNLQH LDLSSNKFYG DIGSSLSSCG KLSFLNLTNN QFVGLVPKLQ 300

SESLQYLYLR GNDFQGVYPN QLADLCKTVV ELDLSYNNFS GMVPESLGEC SSLELVDISN 360

NNFSGKLPVD TLLKLSNMKT MVLSFNKFVG VLPDSFSNLL KLETLDVSSN NLTGVIPSGI 420

CKDPMNNLKV LYLQNNLFEG PIPDSLSNCS QLVSLDLSFN YLTRRIPSSL GSLSKLKDLI 480

LWLNQLSGEI PQELMYLQAL ENLILDFNDL TGPIPASLSN CTKLNWISLS NNQLSGEIPA 540

SLGRLSNLAI LKLGNNSISG NIPAELGNCQ SLIWLDLNTN FLSGSIPPPL FKQSGNIAVA 600

LLTGKRYVYI KNDGSKECHG AGNLLEFGGI RQEQLGRIST RHPCNFTRVY RGITQPTFNH 660

NGSMIFLDLS YNKLEGSIPK ELGTMYYLSI LNLGHNDLSG MIPQDLGGLK NVAILDLSYN 720

RFNGPIPNSL TSLTLLGEID LSNNNLSGMI PESAPFDTFP DYRFANNSLC GYPLPLPCSS 780

GPKSDANQHQ KSHRRQASLA GSVAMGLLFS LFCIFGLIIV AIETKKRRKK KEAALEAYMD 840

GHSHSATANS AWKFTSAREA LSINLAAFEK PLRKLTFADL LEATNGFHND SLVGSGGFGD 900

VYKAQLKDGS VVAIKKLIHV SGQGDREFTA EMETIGKIKH RNLVPLLGYC KVGEERLLVY 960

EYMKYGSLED VLHDRKKIGI KLNWPARRKI AIGAARGLAF LHHNCIPHII HRDMKSSNVL 1020

LDENLEARVS DFGMARLMSA MDTHLSVSTL AGTPGYVPPE YYQSFRCSTK GDVYSYGVVL 1080

LELLTGKQPT DSADFGDNNL VGWVKLHAKG KITDVFDREL LKEDPSIEIE LLQHLKVACA 1140

CLDDRHWKRP TMIQVMAMFK EIQAGSGMDS TSTIGADDVN FSAVEGGIEM GINESIKEGN 1200

ELSKHL 1206

Nucleotide Sequence
(FASTA)

ATGAAAGCTC ACAAAACTGT GTTTTACCAA CACCCTTTAA GCTTAAACAA GCTTTTCTTT 60

GTTCTTCTTC TTATCTTCTT TCTTCCTCCA GCTTCACCAG CTTCTGTTAA TGGTCTTTTT 120

AAAGACTCCC AACAGCTTCT TTCCTTTAAA GCTGCACTTC CACCAACCCC TACTCTGCTT 180

CAGAACTGGT TGCCATCTAC TGACCCTTGT AGTTTCACTG GTGTTTCATG CAAGAATTCT 240

AGAGTTTCTT CTATAGATCT CAGTAACACT TTTTTAAGTG TGGATTTCAG TTTGGTCACT 300

TCTTATTTGC TTCCTCTTTC TAATTTGGAG TCTTTAGTGT TAAAGAATGC TAATCTTAGT 360

GGTTCTTTAA CTTCTGCTGC TAAATCCCAA TGTGGGGTTT CTTTAGACTC CATAGATCTA 420

GCTGAAAACA CAATTTCAGG ACCTATTTCT GATATCTCTA GCTTTGGTGT TTGTTCAAAC 480

CTTAAGTCTC TTAATCTTTC TAAGAATTTC TTGGACCCTC CTGGTAAAGA AATACTTAAA 540

GGTGCAACCT TTAGCCTCCA AGTTCTTGAT CTTTCTTACA ATAATATCTC AGGTTTCAAC 600

TTGTTTCCAT GGGTTTCATC TATGGGGTTT GGTGAACTTG AGTTCTTTTC TCTCAAGGGT 660

AACAAACTAG CTGGAAGTAT TCCTGAATTA GACTTCAAGA ATTTGTCACA TTTGGATCTT 720

TCTGCAAATA ATTTCTCAAC TGTTTTTCCT TCATTCAAAG ATTGCTCCAA TTTGCAGCAC 780

TTGGATTTGT CATCCAACAA GTTTTATGGT GATATTGGTT CTTCACTTTC TTCATGTGGG 840

AAGCTCAGTT TTCTCAACCT TACCAATAAC CAGTTTGTAG GTTTGGTCCC TAAACTACAA 900

AGTGAAAGCC TACAGTATTT GTACTTAAGA GGGAATGATT TTCAGGGTGT GTACCCAAAC 960

CAGCTTGCTG ATTTGTGCAA AACTGTGGTG GAATTGGACT TGTCATACAA TAATTTCTCA 1020

GGTATGGTTC CTGAGAGCCT TGGTGAATGT TCAAGTTTGG AACTTGTTGA TATTTCCAAC 1080

AATAATTTCT CTGGTAAGTT GCCTGTTGAT ACTCTCTTGA AGTTGAGTAA TATGAAGACT 1140

ATGGTCTTAT CATTCAACAA ATTTGTTGGT GTTTTGCCTG ATTCTTTCTC TAATTTGCTG 1200

AAATTGGAGA CTTTGGATGT GAGTTCTAAT AATCTCACAG GGGTTATTCC ATCTGGGATT 1260

TGCAAAGATC CTATGAATAA CTTAAAAGTG TTGTACCTTC AGAATAACTT GTTTGAAGGC 1320

CCTATACCTG ACAGTCTAAG CAACTGTTCA CAGCTGGTGT CACTTGATCT TAGCTTTAAT 1380

TACTTGACTA GGAGAATACC ATCTAGTTTG GGGTCATTGT CAAAGCTGAA AGATCTCATC 1440

CTTTGGTTGA ATCAGCTTTC AGGGGAAATC CCACAGGAGT TGATGTACTT GCAGGCTTTA 1500

GAAAATTTGA TTCTTGATTT TAATGACTTA ACTGGACCAA TACCTGCAAG TCTTAGCAAC 1560

TGTACCAAGT TGAATTGGAT TTCATTGTCA AATAACCAAT TGAGTGGTGA GATACCGGCT 1620

TCTCTTGGTC GTTTGTCGAA TCTAGCCATT CTTAAGCTTG GAAACAACTC AATCTCAGGG 1680

AATATACCTG CTGAGTTGGG TAATTGCCAG AGCTTGATAT GGTTGGATCT CAATACTAAT 1740

TTCCTGAGTG GCTCCATTCC ACCGCCTTTG TTCAAGCAAT CTGGAAATAT TGCAGTGGCA 1800

TTGCTGACCG GAAAACGATA TGTGTATATT AAGAATGATG GGAGTAAGGA GTGCCATGGA 1860

GCAGGGAATT TGCTGGAGTT TGGAGGGATT AGACAAGAAC AGCTGGGTAG AATCTCAACA 1920

AGGCATCCTT GCAATTTCAC AAGAGTTTAT AGAGGTATCA CTCAGCCAAC ATTTAACCAC 1980

AATGGCTCTA TGATATTTCT TGATTTATCT TATAATAAGT TGGAAGGTAG TATCCCAAAG 2040

GAATTAGGGA CCATGTACTA TCTGTCTATA TTGAATTTGG GGCATAATGA TCTGTCTGGT 2100

ATGATTCCTC AAGATCTTGG AGGCTTGAAG AATGTTGCAA TTCTTGATCT GTCATATAAT 2160

AGGTTCAATG GCCCGATCCC GAATTCCCTC ACCAGTCTTA CATTGCTTGG AGAGATTGAC 2220

CTGTCAAACA ATAATCTCAG TGGAATGATT CCTGAATCTG CACCATTTGA TACATTCCCT 2280

GATTATAGGT TTGCAAATAA TTCTCTCTGT GGGTATCCTC TCCCCCTACC TTGTAGCTCG 2340

GGGCCGAAAT CGGATGCAAA TCAGCATCAG AAATCTCACC GCAGACAAGC ATCGTTGGCA 2400

GGGAGTGTGG CGATGGGTTT GTTATTTTCC CTCTTTTGTA TCTTTGGTTT GATTATTGTT 2460

GCCATAGAGA CGAAGAAGAG GAGGAAGAAG AAGGAGGCTG CCCTTGAAGC TTATATGGAT 2520

GGTCATTCAC ATTCTGCAAC TGCAAACAGT GCCTGGAAGT TTACGAGTGC TCGTGAGGCG 2580

TTAAGCATTA ACCTCGCAGC ATTTGAGAAG CCTCTCAGGA AGCTCACATT TGCTGATCTT 2640

CTCGAAGCCA CCAATGGTTT CCACAACGAC AGTCTTGTAG GCTCTGGTGG TTTTGGTGAT 2700

GTCTACAAAG CTCAGTTGAA GGATGGCAGT GTTGTAGCCA TTAAGAAGTT GATACATGTC 2760

AGTGGACAGG GTGATCGAGA ATTCACTGCT GAAATGGAAA CCATAGGGAA GATCAAGCAC 2820

AGGAACCTTG TCCCTCTTTT GGGCTACTGC AAAGTAGGGG AAGAAAGACT ACTGGTTTAC 2880

GAATACATGA AGTATGGAAG TCTTGAAGAT GTCCTGCACG ATCGGAAGAA AATCGGGATC 2940

AAGCTGAATT GGCCTGCAAG AAGGAAAATC GCCATTGGAG CTGCGAGAGG GTTGGCTTTC 3000

CTACACCATA ACTGCATTCC ACACATCATT CACCGGGACA TGAAATCAAG TAATGTCTTG 3060

CTTGATGAAA ATTTGGAAGC CAGAGTATCT GATTTCGGAA TGGCAAGGTT AATGAGTGCT 3120

ATGGACACTC ATTTGAGTGT CAGCACTCTT GCAGGCACTC CCGGATACGT TCCTCCTGAA 3180

TATTACCAAA GCTTTAGATG TTCAACAAAA GGAGACGTTT ATAGTTATGG TGTCGTATTA 3240

CTTGAGCTTC TAACCGGCAA ACAGCCAACA GATTCAGCTG ATTTTGGTGA CAACAATCTT 3300

GTCGGATGGG TAAAGTTGCA CGCTAAAGGA AAAATAACTG ATGTCTTCGA TCGAGAGCTA 3360

TTGAAAGAGG ATCCAAGCAT TGAGATTGAA CTTCTACAAC ACTTAAAGGT AGCTTGTGCT 3420

TGCTTAGATG ATCGACATTG GAAACGTCCC ACGATGATAC AAGTTATGGC TATGTTTAAG 3480

GAGATTCAAG CAGGGTCAGG CATGGATTCG ACATCCACAA TCGGAGCTGA TGATGTCAAT 3540

TTTAGTGCAG TTGAAGGAGG GATAGAAATG GGGATAAATG AAAGTATAAA AGAAGGCAAT 3600

GAGCTAAGCA AACACCTTTG A 3621

Domain Profile

S: 1     fsednrigeGgfgevyrgelknt.avavkklkeeadlslkelkqsfltElkvlarfrHdn  59

         f++d  +g Ggfg+vy+++lk+  +va+kkl +       + +++f +E++++ +++H n

Q: 887   FHNDSLVGSGGFGDVYKAQLKDGsVVAIKKLIHVS----GQGDREFTAEMETIGKIKHRN  942

         8999****************976599*****8765....456899***************

S: 60    ilellgysaeseklcLvYqymknGsLedrLqcq.kgsepLsWpqRlsillGtaraiefLH  118

         +++llgy+  +e+  LvY+ymk GsLed L+ + k    L Wp R +i++G+ar++ fLH

Q: 943   LVPLLGYCKVGEERLLVYEYMKYGSLEDVLHDRkKIGIKLNWPARRKIAIGAARGLAFLH  1002

         *******************************99455678********************9

S: 119   easp.slihgdiksaNiLLDekltpKlgDfglarfapesekqsstvlrtskvrgtlaYlp  177

         ++   ++ih+d+ks+N+LLDe+l+++++Dfg+ar      +  +t l +s++ gt  Y+p

Q: 1003  HNCIpHIIHRDMKSSNVLLDENLEARVSDFGMAR----LMSAMDTHLSVSTLAGTPGYVP  1058

         99777*****************************....445556677799**********

S: 178   eefirvgqltvkvDvySfGiVllEvltGlra.vdedrktkyLkdllkeeieeekveilek  236

         +e+ ++ + ++k DvyS+G+VllE+ltG +   + d   ++L+  +k +++ + ++++++

Q: 1059  PEYYQSFRCSTKGDVYSYGVVLLELLTGKQPtDSADFGDNNLVGWVKLHAKGKITDVFDR  1118

         ****************************998456778999********************

S: 237   fldkkagkleeellealielalaclaekakkrPtmsqvle  276

          l k+ +++e ell+ l ++a+acl++++ krPtm qv+

Q: 1119  ELLKEDPSIEIELLQHL-KVACACLDDRHWKRPTMIQVMA  1157

         ************99876.678****************986

Domain Sequence
(FASTA)

FHNDSLVGSG GFGDVYKAQL KDGSVVAIKK LIHVSGQGDR EFTAEMETIG KIKHRNLVPL 60

LGYCKVGEER LLVYEYMKYG SLEDVLHDRK KIGIKLNWPA RRKIAIGAAR GLAFLHHNCI 120

PHIIHRDMKS SNVLLDENLE ARVSDFGMAR LMSAMDTHLS VSTLAGTPGY VPPEYYQSFR 180

CSTKGDVYSY GVVLLELLTG KQPTDSADFG DNNLVGWVKL HAKGKITDVF DRELLKEDPS 240

IEIELLQHLK VACACLDDRH WKRPTMIQVM A 271

Keyword

ATP-binding; Kinase; Leucine-rich repeat; Membrane; Nucleotide-binding; Repeat; Serine/threonine-protein kinase; Transferase; Transmembrane; Transmembrane helix.

Sequence Source

Ensembl

Orthology

Ortholog group

Arabidopsis lyrata"; ?>Arabidopsis thaliana"; ?>Brachypodium distachyon"; ?>Brassica rapa"; ?>Glycine max"; ?>Hordeum vulgare"; ?>Musa acuminata"; ?>Oryza brachyantha"; ?>Oryza indica"; ?>Oryza sativa"; ?>Populus trichocarpa"; ?>Setaria italica"; ?>Solanum lycopersicum"; ?>Sorghum bicolor"; ?>Vitis vinifera"; ?>Zea mays"; ?>

Gene Ontology

GO:0016021	; C:integral to membrane
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR001611	; Leu-rich_rpt.
IPR013210	; LRR-contain_N2.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00560	; LRR_1; 1.
PF08263	; LRRNT_2; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013