EPS-PHP-00054

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-PHP-00054

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	138.8	5.2E-40	221	490	270

Status

Unreviewed

Ensembl Protein

PP1S81_123V6.1

UniProt Accession

A9SIB5;

Protein Name

Protein Synonyms/Alias

Predicted protein;

Gene Name

A9SIB5_PHYPA

Gene Synonyms/Alias

PHYPADRAFT_185240;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
PP1S81_123V6	PP1S81_123V6.1	PP1S81_123V6.1

Organism

Physcomitrella patens

Functional Description

Protein Length

1194

Protein Sequence
(FASTA)

MGCVNGKRSG AQRREAKHQQ QLQHQHRQQP AILPSLNDAA DVLTSDSDED VFGDGMGIQM 60

CLPGRDSKPN SRSGTPKLLS EANTPKLKSE AGTPKQGSKY GLGLPKPKSK SGTPKTRSET 120

GTPKTKSDAY TSPIAKPEGG GSKSGSPYEH GSTRRNSHSS SHFLESLDLD LGISRLSRIS 180

DQYLPASGSR VVRVPDGNYE LRFSYLTQRG YYPEALDKVN QDSFCAHTVF GDNPDDHFFG 240

VFDGHGEFGT QCSQFVKKNL CENLLRNQHY LTDPVQAYHE AFLTTNTQLH RNSIDDSMSG 300

TTAITALVRG RTLYVANVGD SRAVIAERRG NNFVAVDLST DQTPFREDEC TRVKACGARI 360

LTLDQLEGLK NPDVRCWGGE GDDDGDPPRL WVQNGMYPGT AFTRSIGDSA AEEIGVIAMP 420

EVLVMDLTSQ HPFFVIASDG VFEFLNSQTV VDMVAKYNDP KEACAAIVAE SYRLWLQYET 480

RTDDITIIVV HIQNLNDDHV TVESYYRDSP VLPLKSPGVK SPGRASRDVF KGSRPARSDF 540

SRARARAIEA SLDPDEPWVP TTEPHVKTPE EEAQIKRALQ GNFLFEGLTE RQRHTLIDCM 600

DLLEVNAGDV IIRQGFESDL FYIVESGEFE ASFSQSGTGT AGAVQDAGKV VHLYTADSNP 660

CFGELALMYN KPGLATVRAA SNGSLWVLER EAFRGVLLMK YMQRPSVKIL RSVEIFSKLS 720

LSHLHSLAEA LTEATFEEGQ VIVKKDQKLD AFYIVNKGDV DITYHDSEND DGEQFQLPRA 780

SLEWTGERCA FIERSDDIRQ DLPQAKSFGE WLLTNVPAKS ITVVATTDVE CWYISRRAFE 840

AAVGPLSLIL KEDAKYMEKM SHLRRLQLAE VDVHAFQRIT LKDLDWQETV YSTDCCDVGV 900

VLCKKSDDVI SMKRYQRRKV QRLGREGQVL LERTLFKQLR PSPFVPHLLA TPIDSDNVAL 960

VLNCVLAGPL ELLLRSPLDE NSARFLVANV VLAVELLHKD GVVYRGISPD VLMIDRKGRL 1020

QLVDFRFAKQ MSDERTFTVC GMADFLAPEI IQGQGHGLAS DWWAVGVLMY FMLQTELPFG 1080

SWRDNELEIF GRIARRQLTF PSSFSPEAVD LIDKLLVVDP TKRLGCDSHG SLAIREHPWF 1140

RGINWDKHLD CSVEVPSEIM TRLQLAIDFL PVDDSYQVFD LQPDEDDPPW LDGW 1194

Nucleotide Sequence
(FASTA)

ATGGGATGTG TTAATGGCAA GAGGTCCGGG GCACAGCGGC GAGAGGCCAA GCATCAGCAG 60

CAGCTTCAAC ATCAGCACCG CCAGCAGCCA GCGATCTTGC CCTCTCTGAA CGATGCAGCG 120

GATGTCCTCA CCTCCGACAG TGACGAAGAT GTTTTTGGAG ATGGCATGGG CATTCAAATG 180

TGCTTGCCTG GGCGGGACAG TAAACCGAAC TCACGTTCTG GAACTCCGAA GCTCCTCTCG 240

GAGGCCAACA CCCCGAAGCT GAAATCTGAA GCTGGTACTC CAAAACAGGG TAGCAAATAT 300

GGGCTTGGGC TGCCGAAACC AAAGTCGAAG TCGGGGACGC CCAAGACTAG GTCAGAGACT 360

GGAACTCCAA AGACGAAATC GGATGCCTAC ACCTCGCCCA TTGCCAAACC CGAAGGAGGA 420

GGTTCGAAGT CTGGTTCTCC TTATGAGCAT GGTTCCACTC GAAGAAATAG TCACAGCTCC 480

TCTCATTTCT TGGAGTCTCT CGACCTTGAC CTCGGAATTT CTCGCCTCTC TCGAATCTCG 540

GATCAGTATC TCCCTGCTAG CGGCTCCCGT GTTGTCAGAG TTCCTGACGG TAACTATGAG 600

CTGCGATTCT CCTATTTGAC GCAGCGGGGT TACTATCCCG AAGCGCTTGA CAAAGTGAAT 660

CAGGACAGTT TCTGTGCTCA TACGGTATTT GGCGATAATC CTGACGACCA TTTCTTTGGA 720

GTGTTTGATG GTCATGGCGA GTTTGGAACA CAGTGCTCCC AGTTTGTGAA AAAAAATCTA 780

TGTGAAAACT TGCTGCGGAA CCAGCACTAC CTTACAGATC CTGTTCAAGC ATACCACGAA 840

GCATTTTTAA CAACCAATAC ACAGCTGCAT CGCAACAGTA TTGATGATTC AATGAGTGGC 900

ACGACAGCCA TAACCGCGCT TGTGAGAGGC CGGACTCTCT ATGTGGCCAA TGTGGGCGAT 960

TCGCGAGCAG TAATTGCAGA GAGAAGAGGT AACAATTTTG TGGCTGTTGA TCTCTCCACT 1020

GACCAGACGC CTTTTCGCGA AGATGAATGC ACCCGTGTGA AGGCTTGTGG CGCGCGGATT 1080

CTGACCCTCG ACCAGCTTGA AGGCTTGAAA AATCCTGATG TTAGGTGTTG GGGCGGAGAG 1140

GGTGACGATG ACGGTGATCC TCCACGGTTA TGGGTGCAAA ATGGTATGTA TCCTGGAACA 1200

GCTTTCACAC GAAGTATAGG AGACTCTGCA GCTGAGGAGA TTGGCGTTAT CGCAATGCCT 1260

GAGGTCCTTG TCATGGACCT CACGTCGCAG CACCCTTTCT TTGTTATAGC CAGTGATGGT 1320

GTATTCGAAT TTTTAAACAG CCAAACTGTT GTTGACATGG TTGCCAAGTA CAACGATCCA 1380

AAGGAAGCTT GTGCAGCTAT CGTGGCAGAA TCATATCGGC TGTGGCTGCA ATACGAAACT 1440

CGTACTGACG ACATTACAAT AATTGTTGTG CACATTCAAA ACCTCAATGA CGACCACGTT 1500

ACAGTGGAGT CATATTACAG AGATTCACCA GTGCTACCTC TCAAGTCCCC TGGAGTAAAA 1560

TCCCCAGGTC GAGCCTCTAG AGATGTATTC AAAGGCAGTC GGCCTGCCCG CAGCGATTTC 1620

TCAAGGGCAC GAGCCCGTGC TATTGAAGCT TCTTTGGATC CAGACGAACC TTGGGTGCCC 1680

ACAACGGAGC CCCATGTAAA AACTCCAGAA GAAGAGGCAC AAATTAAGAG AGCTCTGCAA 1740

GGTAACTTCT TGTTCGAAGG GTTGACAGAG AGGCAACGGC ACACGCTAAT TGATTGCATG 1800

GATTTATTGG AAGTAAATGC CGGTGATGTC ATAATACGGC AGGGTTTTGA GAGCGATCTA 1860

TTCTACATAG TAGAATCTGG TGAATTTGAG GCTTCATTTT CACAGTCTGG AACTGGCACT 1920

GCTGGTGCTG TTCAGGATGC TGGGAAGGTG GTCCATTTGT ATACTGCGGA TTCAAACCCC 1980

TGCTTTGGAG AGCTTGCACT CATGTATAAT AAACCAGGGC TTGCAACAGT GCGGGCGGCA 2040

TCGAACGGTA GTCTGTGGGT ACTAGAGCGG GAAGCCTTTC GAGGAGTTCT TTTGATGAAA 2100

TACATGCAGC GGCCGTCGGT GAAGATCTTA CGATCGGTGG AAATATTTTC TAAGCTATCC 2160

TTGTCACATC TGCATAGCCT AGCAGAAGCT CTGACCGAAG CTACATTTGA GGAAGGTCAA 2220

GTTATAGTGA AAAAAGATCA GAAACTTGAC GCATTCTATA TTGTCAACAA AGGCGATGTG 2280

GACATAACCT ACCATGATAG TGAGAATGAT GATGGTGAGC AGTTTCAGTT ACCCAGGGCA 2340

AGCTTGGAGT GGACAGGAGA AAGATGCGCC TTCATTGAAC GTAGTGATGA TATTCGGCAG 2400

GATTTACCCC AAGCAAAGTC TTTTGGTGAA TGGTTGCTTA CTAATGTGCC TGCGAAATCC 2460

ATCACTGTGG TAGCTACCAC TGACGTGGAG TGCTGGTATA TTTCACGGCG AGCATTTGAA 2520

GCTGCTGTTG GTCCTCTAAG TTTAATTCTC AAGGAAGACG CAAAGTACAT GGAGAAAATG 2580

TCACATTTGC GTAGACTCCA ACTTGCGGAG GTGGATGTAC ACGCTTTTCA GAGAATTACA 2640

CTTAAGGATT TGGACTGGCA AGAAACTGTC TATTCAACCG ATTGCTGTGA TGTCGGTGTG 2700

GTGCTCTGCA AGAAATCAGA TGACGTCATA AGCATGAAAA GGTACCAGAG ACGTAAAGTT 2760

CAGAGACTCG GTCGGGAGGG CCAAGTCCTA TTGGAGAGAA CTCTTTTCAA GCAACTGAGG 2820

CCTTCCCCAT TCGTGCCGCA TCTCTTGGCC ACCCCTATTG ACAGTGACAA TGTGGCACTC 2880

GTTCTTAATT GTGTGTTAGC TGGGCCTCTA GAACTTCTAC TTCGGTCACC TTTAGACGAG 2940

AACTCAGCTC GTTTTCTGGT CGCCAACGTG GTATTAGCCG TCGAACTTCT GCACAAGGAT 3000

GGCGTTGTAT ATCGTGGCAT CTCTCCCGAT GTTCTTATGA TAGATCGGAA AGGACGACTT 3060

CAGCTGGTTG ATTTTCGGTT TGCAAAGCAA ATGTCGGATG AGCGCACTTT CACAGTCTGT 3120

GGCATGGCTG ATTTCTTAGC ACCCGAGATC ATTCAAGGAC AAGGTCATGG CCTGGCTTCT 3180

GACTGGTGGG CGGTAGGTGT GTTAATGTAC TTCATGTTGC AAACTGAGCT TCCATTTGGA 3240

TCATGGCGGG ACAACGAGCT TGAAATTTTT GGTAGAATAG CCCGTCGGCA GCTTACGTTT 3300

CCTTCAAGTT TCAGCCCTGA AGCGGTTGAC CTCATTGACA AGCTGCTGGT GGTGGACCCA 3360

ACCAAGAGAC TGGGCTGTGA CAGCCATGGA TCGCTTGCCA TAAGGGAACA TCCTTGGTTC 3420

CGAGGTATAA ACTGGGACAA GCACCTCGAT TGCAGTGTGG AAGTTCCTTC AGAGATCATG 3480

ACACGCCTTC AGTTGGCCAT AGACTTTCTT CCCGTGGATG ATAGTTATCA AGTGTTTGAT 3540

CTCCAACCCG ATGAAGACGA TCCACCATGG CTTGATGGCT GGTGA 3585

Domain Profile

S: 16    edavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheilaeelesseseerkv  75

         +d++ +++ f+++p+     +ffgv+DGhg  e   +cs+ +++ l e+l  ++   ++

Q: 221   QDSFCAHTVFGDNPDD----HFFGVFDGHG--EFGTQCSQFVKKNLCENLLRNQHYLTDP  274

         5677778889998886....8********9..6666677777777777766566677777

S: 76    kkalakaFlstdeelkvleeksldidksGstavvalikdsklyvanvGdSravLcr.ngk  134

          +a  +aFl+t  +l   +++s d + sG+ta +al+++ +lyvanvGdSrav++   g+

Q: 275   VQAYHEAFLTTNTQL---HRNSIDDSMSGTTAITALVRGRTLYVANVGDSRAVIAErRGN  331

         789999******999...888889999****************************95445

S: 135   ...avelssdHkpsredEleRieeaggsvilkdgaRv.......................  168

            av ls+d +p redE  R+++ g+++   d   +

Q: 332   nfvAVDLSTDQTPFREDECTRVKACGARILTLD--QLeglknpdvrcwggegdddgdppr  389

         799***********************9999998..6667799999***************

S: 169   .......lGvLavsRalGdlylkpy.vtpePevtshrltsedefliLasDGlwdvvsnee  220

                 + +a +R++Gd   +++ v++ Pev +++lts++ f+++asDG+++ +++++

Q: 390   lwvqngmYPGTAFTRSIGDSAAEEIgVIAMPEVLVMDLTSQHPFFVIASDGVFEFLNSQT  449

         ****9987779************888**********************************

S: 221   avslvrdvlekkeaeqeaakkLvklalargsk.dnvsaivv  260

         +v++v ++ + kea+ ++  +  +l l+++++ d++++ivv

Q: 450   VVDMVAKYNDPKEACAAIVAESYRLWLQYETRtDDITIIVV  490

         **********7777777666666666666554589988886

Domain Sequence
(FASTA)

QDSFCAHTVF GDNPDDHFFG VFDGHGEFGT QCSQFVKKNL CENLLRNQHY LTDPVQAYHE 60

AFLTTNTQLH RNSIDDSMSG TTAITALVRG RTLYVANVGD SRAVIAERRG NNFVAVDLST 120

DQTPFREDEC TRVKACGARI LTLDQLEGLK NPDVRCWGGE GDDDGDPPRL WVQNGMYPGT 180

AFTRSIGDSA AEEIGVIAMP EVLVMDLTSQ HPFFVIASDG VFEFLNSQTV VDMVAKYNDP 240

KEACAAIVAE SYRLWLQYET RTDDITIIVV 270

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Arabidopsis lyrata"; ?>Arabidopsis thaliana"; ?>Brachypodium distachyon"; ?>Brassica rapa"; ?>Chlamydomonas reinhardtii"; ?>Glycine max"; ?>Hordeum vulgare"; ?>Musa acuminata"; ?>Oryza brachyantha"; ?>Oryza glaberrima"; ?>Oryza indica"; ?>Oryza sativa"; ?>Populus trichocarpa"; ?>Selaginella moellendorffii"; ?>Setaria italica"; ?>Solanum lycopersicum"; ?>Solanum tuberosum"; ?>Sorghum bicolor"; ?>Vitis vinifera"; ?>Zea mays"; ?>

Gene Ontology

GO:0005952	; C:cAMP-dependent protein kinase complex
GO:0005524	; F:ATP binding
GO:0008603	; F:cAMP-dependent protein kinase regulator activity
GO:0046872	; F:metal ion binding
GO:0004672	; F:protein kinase activity
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

ppp:PHYPADRAFT_185240

;

InterPros

IPR002373	; cAMP/cGMP_kin.
IPR018490	; cNMP-bd-like.
IPR000595	; cNMP-bd_dom.
IPR011009	; Kinase-like_dom.
IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR000719	; Prot_kinase_cat_dom.
IPR015655	; Protein_Pase_2C.
IPR014710	; RmlC-like_jellyroll.

Pfam

PF00027	; cNMP_binding; 2.
PF00069	; Pkinase; 1.
PF00481	; PP2C; 1.

SMARTs

SM00100	; cNMP; 2.
SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS50042	; CNMP_BINDING_3; 2.
PS01032	; PP2C; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

PR00103

; CAMPKINASE.

Created Date

20-Feb-2013