EPS-SCP-00001

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-SCP-00001

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	38.5	3.2E-10	88	249	162

Status

Reviewed

Ensembl Protein

SPAC1556.03.1:pep

UniProt Accession

Q09189; Q9UTJ6;

Protein Name

5-azacytidine resistance protein azr1

Protein Synonyms/Alias

Gene Name

azr1

Gene Synonyms/Alias

azr1; SPAC1556.03;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
SPAC1556.03	SPAC1556.03.1:pep	SPAC1556.03.1

Organism

Schizosaccharomyces pombe

Functional Description

Confers azacytidine resistance in high copy.

Protein Length

299

Protein Sequence
(FASTA)

MNVTRLYFRV AGTKQFARYV HKYAAYSSTS FQKKKSHFPS PATLDHPDAG EDAFINLRNE 60

NYILNAVFDG VGGWANVGID PSIFSWGLVR EIKKVFNNSD EFQPSPLTLL SKAYAALKKS 120

NTVEAGSSTA CLTLFNCGNG KLHSLNLGDS GFLILRNGAI HYASPAQVLQ FNMPYQLAIY 180

PRNYRSAENI GPKMGQATVH DLKDNDLVIL ATDGIFDNIE EKSILDIAGV VDFSSLSNVQ 240

KCLDDLAMRI CRQAVLNSLD TKWESPFAKT AKSFGFKFQG GKVDDTTITC LLIKSKNYE 299

Nucleotide Sequence
(FASTA)

ATGAATGTTA CTCGTCTTTA CTTTCGTGTC GCTGGAACAA AACAGTTCGC CCGATATGTG 60

CACAAATATG CTGCATATTC CTCTACGAGC TTTCAAAAAA AGAAATCTCA TTTCCCATCT 120

CCTGCTACGC TCGATCACCC GGATGCCGGA GAAGACGCTT TTATAAATTT AAGGAATGAA 180

AACTATATCT TAAATGCAGT ATTTGACGGA GTTGGAGGCT GGGCGAATGT GGGGATTGAT 240

CCGTCAATAT TTAGTTGGGG ATTGGTTCGG GAAATAAAAA AAGTCTTTAA CAATTCTGAC 300

GAATTCCAAC CAAGTCCTCT CACTTTACTT TCCAAAGCAT ATGCAGCTTT GAAGAAAAGT 360

AACACTGTTG AGGCTGGCTC AAGCACTGCT TGCCTTACAT TGTTCAATTG CGGAAACGGT 420

AAACTTCATT CATTAAACCT TGGTGACTCA GGATTTCTTA TCCTTAGAAA TGGTGCTATC 480

CATTATGCAT CACCTGCCCA AGTACTCCAA TTTAATATGC CATATCAATT GGCTATATAT 540

CCTAGGAACT ATCGTTCCGC TGAAAACATT GGGCCTAAAA TGGGACAAGC AACTGTGCAC 600

GACCTTAAAG ACAATGACTT GGTAATTTTA GCTACCGATG GCATATTTGA TAATATAGAG 660

GAAAAGTCGA TCTTAGACAT CGCTGGCGTC GTTGATTTTA GCTCTCTTTC GAATGTTCAG 720

AAATGCCTTG ATGATTTGGC TATGCGCATT TGTAGGCAAG CAGTTTTGAA TTCGTTGGAT 780

ACGAAATGGG AATCTCCATT CGCAAAAACG GCAAAGAGTT TTGGTTTCAA GTTTCAAGGA 840

GGGAAAGTGG ATGATACTAC CATTACATGT TTACTGATAA AGTCCAAAAA TTATGAGTAA 900

Domain Profile

S: 22    imgllrsalrelataglepaevlerlnealarnleeeerfatavlaeydpstgkleyana  81

         +++++++++++  + + +p ++l+++++al++  + e+   ta+l  ++  +gkl+  n+

Q: 88    LVREIKKVFNNSDEFQPSPLTLLSKAYAALKKSNTVEAGSSTACLTLFNCGNGKLHSLNL  147

         456677777777777788************99999999**********************

S: 82    Ghpppllvrpdg....gtkfllvstglp..lGilpe.........adyeeael.qlepgd  125

         G++ +l++r+ g        +  ++++p  l i p           ++ +a++ +l+ +d

Q: 148   GDSGFLILRN-GaihyASPAQVLQFNMPyqLAIYPRnyrsaenigPKMGQATVhDLKDND  206

         **********.4477767777778888899999999*********6666666527*****

S: 126   llllyTDGvtEardpdgelfgkerllallaeaegesleelldalvee  172

         l++l+TDG++++ ++++ l + +      + ++ ++++++ld l  +

Q: 207   LVILATDGIFDNIEEKSIL-DIAGVV---DFSSLSNVQKCLDDLAMR  249

         ************9444433.333333...322222244444444333

Domain Sequence
(FASTA)

LVREIKKVFN NSDEFQPSPL TLLSKAYAAL KKSNTVEAGS STACLTLFNC GNGKLHSLNL 60

GDSGFLILRN GAIHYASPAQ VLQFNMPYQL AIYPRNYRSA ENIGPKMGQA TVHDLKDNDL 120

VILATDGIFD NIEEKSILDI AGVVDFSSLS NVQKCLDDLA MR 162

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005739	; C:mitochondrion
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation
GO:0007165	; P:signal transduction

KEGG

spo:SPAC1556.03

;

InterPros

IPR001932

; PP2C-like.

Pfam

PF07228

; SpoIIE; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

Prints

Created Date

20-Feb-2013