| Tag | Content |
|---|
| EKPD ID | EPS-SCP-00025 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| PPP/PP2A | 398.1 | 1.5E-120 | 64 | 256 | 193 |
|
| Status | Reviewed |
| Ensembl Protein | SPBC16H5.07c.1:pep |
| UniProt Accession | P23636; |
| Protein Name | Major serine/threonine-protein phosphatase PP2A-2 catalytic subunit |
| Protein Synonyms/Alias | |
| Gene Name | ppa2 |
| Gene Synonyms/Alias | ppa2; SPBC16H5.07c; |
| Ensembl Information | |
| Organism | Schizosaccharomyces pombe |
| Functional Description | Essential role in cell cycle control. PP2A may beinvolved in controlling the entry into mitosis, possibly acting as an inhibitor. |
| Protein Length | 322 |
Protein Sequence
(FASTA) | | MSIDPANDSK LAPEANDATL GDVDRWIEQL KKCEPLSEAD VEMLCDKARE VLCQENNVQP 60 | | VRNPVTVCGD IHGQFHDLME LFKIGGDVPD MNYLFMGDYV DRGYHSVETV SLLVAMKLRY 120 | | PNRITILRGN HESRQITQVY GFYDECLRKY GSANVWKHFT NLFDYFPLTA LIEDRIFCLH 180 | | GGLSPSIDSL DHVRTLDRVQ EVPHEGPMCD LLWSDPDDRC GWGISPRGAG YTFGQDISET 240 | | FNHANGLSLT ARAHQLVMEG FNWAHDGDVV TIFSAPNYCY RCGNQAAILE VDDTMNQVFL 300 | | QFDPAPREGE PVIARRTPDY FL 322 |
|
Nucleotide Sequence
(FASTA) | | ATGTCTATAG ATCCAGCAAA TGATAGTAAG CTTGCTCCGG AGGCGAATGA CGCTACTCTA 60 | | GGAGACGTTG ACAGATGGAT CGAACAGTTG AAAAAATGCG AGCCTCTGAG CGAAGCTGAC 120 | | GTTGAAATGT TATGCGATAA GGCTCGTGAG GTTTTATGTC AGGAAAATAA TGTCCAACCT 180 | | GTCCGAAATC CAGTTACTGT TTGCGGTGAT ATTCATGGAC AGTTTCATGA TCTGATGGAA 240 | | TTATTTAAAA TTGGAGGTGA TGTGCCTGAT ATGAACTATC TTTTTATGGG TGACTATGTT 300 | | GACAGAGGTT ATCACAGCGT CGAAACTGTA AGTTTGCTTG TTGCAATGAA GTTACGCTAC 360 | | CCTAACCGAA TTACGATTCT TCGAGGAAAT CATGAATCTA GACAAATCAC TCAAGTTTAC 420 | | GGATTTTATG ATGAATGTTT GCGTAAATAT GGATCCGCTA ATGTTTGGAA ACATTTCACA 480 | | AATTTATTTG ACTATTTCCC TTTAACTGCT TTAATTGAAG ACCGTATTTT CTGCCTACAT 540 | | GGAGGTCTTT CCCCGAGCAT TGATTCATTA GACCATGTAC GGACTTTGGA TCGTGTACAA 600 | | GAAGTTCCCC ATGAAGGTCC GATGTGTGAT TTGCTTTGGT CAGACCCTGA TGATAGATGT 660 | | GGTTGGGGAA TTTCTCCTCG TGGTGCCGGA TACACCTTCG GACAAGACAT TTCTGAGACA 720 | | TTTAATCACG CAAATGGATT AAGTTTAACG GCACGAGCCC ATCAGCTAGT TATGGAAGGA 780 | | TTTAATTGGG CACATGATGG AGACGTAGTT ACAATTTTTT CTGCCCCAAA TTATTGTTAT 840 | | CGCTGTGGTA ATCAAGCAGC TATTTTGGAA GTTGATGATA CGATGAATCA AGTCTTTTTA 900 | | CAATTCGATC CTGCCCCACG AGAAGGCGAA CCGGTAATAG CTCGAAGGAC ACCAGACTAC 960 | | TTCCTTTAA 969 |
|
| Domain Profile | S: 1 pvtvcgdvhgqfhdllelfriggkspdtnylflgdyvdrgyysvetvtllvalkvryrer 60 | pvtvcgd+hgqfhdl+elf+igg++pd nylf+gdyvdrgy+svetv+llva+k+ry++r | Q: 64 PVTVCGDIHGQFHDLMELFKIGGDVPDMNYLFMGDYVDRGYHSVETVSLLVAMKLRYPNR 123 | 9*********************************************************** |
| S: 61 itilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdgkifclhggl 120 | itilrgnhesrqitqvygfydeclrkyg+anvwk+ft+lfdy+pltal++++ifclhggl | Q: 124 ITILRGNHESRQITQVYGFYDECLRKYGSANVWKHFTNLFDYFPLTALIEDRIFCLHGGL 183 | ************************************************************ |
| S: 121 spsidtldeiraldrlqevphegplcdllwsdpddregwgisprgagytfgqdiseqfnh 180 | spsid+ld++r+ldr+qevphegp+cdllwsdpddr+gwgisprgagytfgqdise+fnh | Q: 184 SPSIDSLDHVRTLDRVQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDISETFNH 243 | ************************************************************ |
| S: 181 angleliarahql 193 | angl+l arahql | Q: 244 ANGLSLTARAHQL 256 | ************8 |
|
Domain Sequence
(FASTA) | | PVTVCGDIHG QFHDLMELFK IGGDVPDMNY LFMGDYVDRG YHSVETVSLL VAMKLRYPNR 60 | | ITILRGNHES RQITQVYGFY DECLRKYGSA NVWKHFTNLF DYFPLTALIE DRIFCLHGGL 120 | | SPSIDSLDHV RTLDRVQEVP HEGPMCDLLW SDPDDRCGWG ISPRGAGYTF GQDISETFNH 180 | | ANGLSLTARA HQL 193 |
|
| Keyword | Cell cycle; Cell division; Complete proteome; Hydrolase; Iron; Manganese; Metal-binding; Methylation; Mitosis; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |