EKS-SCP-00059

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SCP-00059

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	353.6	1.8E-106	74	359	286

Status

Reviewed

Ensembl Protein

SPBC18H10.15.1:pep

UniProt Accession

O60145;

Protein Name

Serine/threonine-protein kinase ppk23

Protein Synonyms/Alias

Gene Name

ppk23

Gene Synonyms/Alias

ppk23; SPBC18H10.15;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
SPBC18H10.15	SPBC18H10.15.1:pep	SPBC18H10.15.1

Organism

Schizosaccharomyces pombe

Functional Description

Protein Length

398

Protein Sequence
(FASTA)

MAGSKWETEE TNQFAIENQK LEEEWRKKRR LEKKRKRKIL EEEEKAEERN IDACRLYLMG 60

NTPELKSCNS IDDYEILEKI EEGSYGIVYR GLDKSTNTLV ALKKIKFDPN GIGFPITSLR 120

EIESLSSIRH DNIVELEKVV VGKDLKDVYL VMEFMEHDLK TLLDNMPEDF LQSEVKTLML 180

QLLAATAFMH HHWYLHRDLK PSNLLMNNTG EIKLADFGLA RPVSEPKSSL TRLVVTLWYR 240

APELLLGAPS YGKEIDMWSI GCIFAEMITR TPLFSGKSEL DQLYKIFNLL GYPTREEWPQ 300

YFLLPYANKI KHPTVPTHSK IRTSIPNLTG NAYDLLNRLL SLNPAKRISA KEALEHPYFY 360

ESPRPKDPKF FPTFPSKAKG ESKEKNVFQS FRSASPKK 398

Nucleotide Sequence
(FASTA)

ATGGCAGGCT CCAAGTGGGA GACAGAAGAA ACGAATCAAT TCGCAATTGA AAATCAAAAA 60

TTAGAAGAGG AATGGCGTAA AAAGCGACGG TTAGAAAAAA AAAGAAAAAG AAAAATATTA 120

GAGGAAGAAG AGAAAGCTGA AGAAAGAAAC ATTGATGCTT GCAGGCTCTA CTTGATGGGG 180

AATACACCTG AACTTAAGTC TTGCAATTCT ATTGATGATT ATGAAATATT GGAAAAAATT 240

GAGGAGGGAT CTTACGGAAT CGTTTATCGA GGTCTTGACA AAAGTACGAA TACCCTGGTT 300

GCACTCAAAA AGATTAAGTT TGACCCTAAT GGAATTGGAT TCCCTATTAC TAGTCTGCGA 360

GAAATTGAAT CACTATCCAG CATTCGACAT GATAATATTG TAGAATTGGA AAAAGTGGTT 420

GTTGGTAAAG ATTTGAAGGA TGTTTACCTA GTTATGGAGT TCATGGAACA TGATCTCAAA 480

ACATTACTTG ATAACATGCC CGAAGATTTC TTACAATCTG AAGTCAAAAC ACTGATGCTT 540

CAACTTTTGG CTGCCACGGC ATTTATGCAT CACCATTGGT ATCTACATAG AGATTTAAAG 600

CCTTCTAACT TGCTAATGAA TAACACCGGC GAAATCAAAC TCGCCGACTT TGGATTGGCA 660

AGGCCAGTAT CAGAACCCAA ATCCTCTTTG ACACGCTTAG TTGTGACTCT TTGGTATCGT 720

GCTCCTGAAC TTTTGCTTGG TGCACCAAGC TATGGTAAAG AAATTGACAT GTGGAGCATT 780

GGATGTATCT TCGCTGAAAT GATTACTAGG ACTCCTTTGT TTTCTGGGAA AAGTGAGTTA 840

GATCAATTAT ACAAGATATT CAATTTGCTC GGTTATCCGA CTAGGGAAGA GTGGCCCCAA 900

TATTTTCTTC TTCCTTATGC AAACAAAATT AAACACCCTA CGGTCCCTAC CCACTCTAAG 960

ATTCGTACTT CTATCCCTAA TTTAACGGGA AACGCGTACG ATTTATTAAA TCGACTTTTA 1020

AGTCTAAATC CTGCGAAGAG AATATCTGCC AAAGAAGCAC TAGAACATCC TTATTTTTAC 1080

GAATCTCCCA GACCCAAGGA TCCTAAATTT TTTCCTACTT TTCCTAGTAA GGCCAAAGGT 1140

GAATCAAAAG AAAAAAACGT GTTTCAAAGT TTTCGTAGTG CATCTCCAAA GAAGTGA 1197

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         ye leki+eG+yg vy++ dk+t+++vAlKki+ + +  g+pit+lrEi+ l +++h+ni

Q: 74    YEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIRHDNI  133

         899*********************************************************

S: 61    vkLlevva.kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsn  119

         v+L +vv+ kd k++yLv+ef+e+dLk+ll+++++ ++ ++evk+l+lqll + a++H++

Q: 134   VELEKVVVgKDLKDVYLVMEFMEHDLKTLLDNMPE-DFLQSEVKTLMLQLLAATAFMHHH  192

         *******95666***********************.9999********************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYs  179

         + lHRDlKp+NlL++++g++klaDfGlar +s+p++++t+ vvTlwYraPelLlga +Y+

Q: 193   WYLHRDLKPSNLLMNNTGEIKLADFGLARPVSEPKSSLTRLVVTLWYRAPELLLGAPSYG  252

         ************************************************************

S: 180   tavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksf  238

         +++D+Ws+gci+ae++tr+plf+gkse dql +if+llg p++++wp++  lp ++  +

Q: 253   KEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPTREEWPQYFLLPYANkIKH  312

         ******************************************************997677

S: 239   pkkkkk.klkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         p+ +++ k+++ +++l+ +a+dll++ll+l+p+kRisakeal+h+yf

Q: 313   PTVPTHsKIRTSIPNLTGNAYDLLNRLLSLNPAKRISAKEALEHPYF  359

         77776679**************************************9

Domain Sequence
(FASTA)

YEILEKIEEG SYGIVYRGLD KSTNTLVALK KIKFDPNGIG FPITSLREIE SLSSIRHDNI 60

VELEKVVVGK DLKDVYLVME FMEHDLKTLL DNMPEDFLQS EVKTLMLQLL AATAFMHHHW 120

YLHRDLKPSN LLMNNTGEIK LADFGLARPV SEPKSSLTRL VVTLWYRAPE LLLGAPSYGK 180

EIDMWSIGCI FAEMITRTPL FSGKSELDQL YKIFNLLGYP TREEWPQYFL LPYANKIKHP 240

TVPTHSKIRT SIPNLTGNAY DLLNRLLSLN PAKRISAKEA LEHPYF 286

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Nucleus; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0051519	; P:activation of bipolar cell growth
GO:0007165	; P:signal transduction

KEGG

spo:SPBC18H10.15

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; FALSE_NEG.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013