EKS-SCP-00089

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SCP-00089

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	350.9	1.8E-105	1955	2242	288

Status

Reviewed

Ensembl Protein

SPBC216.07c.1:pep

UniProt Accession

Q9Y7K2; O94507;

Protein Name

Phosphatidylinositol 3-kinase tor2

Protein Synonyms/Alias

PI3-kinase tor2; PI3K tor2; PtdIns-3-kinase tor2;

Gene Name

tor2

Gene Synonyms/Alias

tor2; SPBC216.07c, SPBC646.01c;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
SPBC216.07c	SPBC216.07c.1:pep	SPBC216.07c.1

Organism

Schizosaccharomyces pombe

Functional Description

Phosphatidylinositol 3-kinase homolog required for G1progression (By similarity).

Protein Length

2337

Protein Sequence
(FASTA)

MKEFPGLKSR NEEIRNKAAN DLYEYVIAYS RELSGEALVQ FNNDVNKYVY TLIHSTDPLD 60

RLAGVTAINR LIDYEGEDTT RITRFANYLR IILPGTDQKA TVLAAKALGR LAVPGGALTS 120

EFVNFEVKRA LEWLQGERNE NRRYAAVLIL KELAKNTSTL IYAHIDSIFE LLWHGLRDPK 180

VTIRIASADA LSEFLKIVRQ RDSSIRLQWY TSILNEAQRG VAQGSSDYIH GSLLVYRQLF 240

LKAGMFMHER YREVSDIILQ FRDHKDLLIR KTVTELIATL AAYNPDEFVS NYLHVCMLHL 300

LNLLKKENVK MLAFATIGKV AVAITNSIIP YLDPICDSIK ESLKIHIRNK SASDAAIFQC 360

ISLLSIALGQ AFSNYAYDLF DLIFASGLSE ASYRALSDLA HNIPPLLPVI QERLLDMLSK 420

ILSGRPFIPP GCPPQYVARS LKSSKSASLK TGFFPNDVYI LALKVLGNFD FSGYILNEFV 480

KDCVVVYLEN NDPEVRKTAS ITCSQLFARD PILSQTSDHA IQVVAEVLEK LLTVGICDTV 540

PDIRLTVLNS LDSRFNKHLA QADKIRLLFI AINDENFAVR ESALRIIGRL NVYNPAYVMP 600

YLRKIMLKTL TILDYSTIIR TKEENAKLLC LLIAAAPRLI ESHVEPILQI LLPKAKDSSS 660

IVAASIVNSL GEICQISGEV IVPFIKDLMP LIIEALQDQS SPIRRAAALK ALGNLSSSTG 720

YVIDPYIEFP SLLDILIGIT KTEQDITIRR ETIKLIGTLG ALDPNRHRVL EKGTEKVVPE 780

QKNIPPDISL LMSGIGPSSD EYYPTVVITA LMSILKDPSL TIHHTAVIQA VMYIFKTMGL 840

RCAPFLSQII PEFIAVMRTC PTNILEFYFQ QLSILVLIVR QHIRSFLPDL FKLIKDFWNP 900

HSNLQFTILS LIESLARAMQ GEFKPYLPSL LVMMLQIFDS DVSVDSVSTK KVLHAFIVFG 960

DTLADYFHML LDPILRLYER NDVSIGIKES IMITIGRLSM VINLSEYASR IIHPVMRMLS 1020

CNNASLIRVS MDTVCALIYQ LNVDFAIFIP MIDKCLKMNG VTHETYSILV EQFLQEQPLP 1080

IKLNPYEKYD KPKLDVVASA ADITSKKLPV NQEILRNAWE ASQRSTKDDW QEWIRRLGVA 1140

LLRESPSHAL RACAALAAAY QPLARDLFNA SFVSCWSELY DHFQEELVKS IEIALTSPHI 1200

SPEIIQILLN LAEFMEHDDK PLPIDIRTLG AYAAKCHAFA KALHYKELEF IEEELVTKPS 1260

VDTIEALISI NNQLQQPDAA IGILKHAQQH DKMNLKETWY EKLQRWEDAL SAYEKREAAG 1320

AGNFEITMGK LRCLHALGEW DRLSQLAQEN WIHAGHDARR YIAPLSVAAA WGLGQWEQMD 1380

EYISVMKSES PDKAFFNAIV ALHRSQFEEA ASYITRARDL LDTELTALVG ESYNRAYSVA 1440

VRVQMLSELE EIITYKKAED KPEVREMIKK TWVRRLKGCQ RNVDVWQRML RIRSLVISPR 1500

DNMEMWIKFA NLCRKSGRIS LAKKSLNLLL EDDENLDNSL VLKKTHPSIV YANLKFLWAV 1560

DDKRKALNSM QEFTSQLISD INVDPALFVQ STSVNTQKSQ EEIQYYFHLL ARCYHKQGQW 1620

QQEIENNWSE GSFDGVLQSY MYATQFDSKW YKAWHSWALA NFEAVKFLEQ SEEQIPSAAY 1680

EQYIIPAVKG FFKSIALSKG NLQDTLRLLN LWFKFGNNSN VINTLNVGIS TVNIDIWLDV 1740

IPQLIARIHA SSLSVRKSVH QLLSDVGRAH PQALVYPLTV AAKSQSSARQ NAALAIMDSL 1800

KTHSPRLVEQ ARLVSHELIR AAILWHEQWH EGLEEASRLY FGDHNIEGMF AVLRPLHEML 1860

ERGPETLREI SFQQAFGRDL VEARDCCIRF EQTGDISDLN QAWDLYYQVF KKIRKQLPQL 1920

TTLDLQYVSP KLLHVHDLEL AVPGTYVSGK PVIRIVKFYP TFNVITSKQR PRRLSIKGSD 1980

GKDYQYVLKG HEDIRQDERV MQLFGLCNNL LLADPETFKR LLSIQRYPVI PLSPDSGLLG 2040

WVLDSDTLHV LIRDYRESRK ILLNIEHRLI IQMAPDYDRL TLLQKVEVFE YALLSTTGQD 2100

LYRVLWLKSR SSEAWLNRRT NYSRTLAVMS MVGYILGLGD RHPSNLMLDR YTGNIIHIDF 2160

GDCFEVAMHR EKFPEKIPFR LTRMLVNAME VSGIEGTFRI TCEHVMRVLR TNKESVMAVL 2220

EAFVYDPLIN WRLAPAYSPS IDEKQSNEPN TLLGETIDGL HRKRLNEEGI TLEERQKPEI 2280

LNQRAITVLN RVSNKLTGRD FKPQQQLDVP SQVEKLILQA TSIENLCLCY IGWCSFW 2337

Nucleotide Sequence
(FASTA)

ATGAAAGAAT TTCCTGGGTT GAAAAGCAGG AATGAAGAAA TTCGCAATAA AGCGGCAAAT 60

GATCTTTATG AATATGTTAT AGCTTATTCT CGAGAATTAT CGGGCGAAGC TTTAGTTCAG 120

TTTAACAATG ATGTTAACAA GTACGTTTAT ACTTTAATTC ACAGTACCGA TCCACTCGAT 180

CGTCTGGCAG GCGTAACTGC CATAAATCGT CTAATTGATT ATGAAGGAGA AGATACTACA 240

AGGATTACTA GATTTGCAAA TTATTTGCGT ATTATTCTTC CAGGAACTGA CCAAAAAGCC 300

ACCGTTCTTG CTGCAAAAGC TTTAGGGAGA CTTGCAGTTC CTGGAGGTGC TCTAACTTCT 360

GAATTTGTGA ACTTCGAAGT TAAACGCGCT TTGGAATGGC TTCAAGGAGA ACGTAATGAA 420

AATCGTAGAT ATGCAGCAGT GCTTATACTT AAGGAGCTTG CCAAAAATAC GTCTACATTA 480

ATCTATGCTC ATATCGATTC AATTTTTGAG CTTTTATGGC ATGGACTTCG GGATCCAAAA 540

GTTACTATTC GAATAGCTTC GGCTGATGCG TTGAGTGAGT TCTTGAAAAT CGTTAGGCAA 600

AGGGATTCAT CCATCCGTCT CCAATGGTAT ACAAGTATTC TCAATGAAGC TCAACGTGGT 660

GTTGCACAGG GTTCTTCTGA TTACATTCAT GGTAGTTTAC TAGTATATCG CCAATTATTT 720

TTAAAAGCTG GAATGTTTAT GCATGAGAGG TATCGAGAAG TATCGGACAT TATATTGCAA 780

TTCAGAGATC ACAAAGATTT GCTTATTCGC AAAACCGTTA CAGAATTGAT TGCTACACTC 840

GCAGCTTATA ATCCAGATGA ATTTGTTTCC AATTATTTAC ACGTTTGTAT GCTCCATCTA 900

CTTAATCTAT TAAAAAAAGA AAATGTTAAG ATGTTGGCGT TTGCCACTAT TGGAAAAGTT 960

GCCGTGGCTA TTACTAATAG CATAATCCCA TATCTTGACC CCATATGCGA TTCAATCAAG 1020

GAAAGTCTAA AAATCCATAT CCGTAATAAA AGTGCTTCGG ATGCTGCAAT TTTTCAATGC 1080

ATTAGCCTAC TTTCTATAGC ACTAGGACAA GCCTTTTCAA ACTATGCGTA TGACCTCTTT 1140

GACTTAATAT TTGCAAGCGG ACTTTCTGAG GCTTCTTACC GTGCTCTCTC AGATCTGGCC 1200

CATAATATAC CTCCATTATT ACCAGTCATA CAGGAACGAC TATTAGATAT GCTCAGCAAA 1260

ATTCTAAGTG GTCGTCCTTT TATTCCTCCA GGATGTCCTC CCCAATATGT AGCAAGATCT 1320

TTAAAATCTT CAAAGAGTGC TTCCCTGAAG ACAGGATTTT TTCCCAATGA CGTCTATATT 1380

TTGGCTCTAA AAGTTTTGGG AAATTTTGAC TTCTCCGGTT ATATTCTTAA TGAATTTGTG 1440

AAGGATTGTG TAGTTGTATA CCTTGAAAAC AATGACCCGG AAGTACGCAA AACCGCCTCC 1500

ATAACCTGCT CCCAACTATT TGCTCGTGAT CCTATTTTAT CGCAGACTAG TGATCATGCG 1560

ATTCAAGTAG TTGCCGAAGT GCTAGAAAAG CTTCTAACAG TTGGTATTTG CGATACTGTT 1620

CCAGATATTC GGCTAACTGT TCTTAATTCT CTCGATTCTC GCTTTAACAA GCATTTAGCC 1680

CAAGCAGATA AAATTCGTTT ACTTTTTATT GCTATTAATG ATGAAAACTT TGCTGTACGA 1740

GAATCTGCAT TACGGATAAT TGGAAGACTA AATGTCTATA ACCCTGCCTA TGTGATGCCA 1800

TATTTAAGGA AAATAATGTT AAAAACTTTA ACAATATTGG ACTATTCTAC AATTATCAGA 1860

ACTAAAGAAG AGAATGCCAA GTTATTGTGT TTATTAATTG CAGCAGCTCC TCGCTTAATA 1920

GAGTCACATG TGGAACCAAT ACTGCAAATA CTTTTACCCA AAGCTAAAGA TTCTAGTTCA 1980

ATTGTGGCAG CTAGTATTGT TAATTCGCTT GGTGAAATAT GCCAAATCAG CGGTGAGGTT 2040

ATTGTTCCTT TTATTAAAGA CTTAATGCCG CTAATAATTG AGGCTTTGCA GGACCAAAGT 2100

TCTCCTATTA GGAGAGCAGC GGCTTTAAAG GCTTTGGGTA ATTTATCAAG CAGCACCGGA 2160

TATGTAATTG ATCCGTATAT TGAATTCCCT TCTTTACTTG ATATACTTAT TGGCATAACG 2220

AAAACCGAAC AAGATATTAC TATTCGTCGA GAGACTATTA AACTAATAGG TACACTTGGT 2280

GCTTTAGATC CCAATAGGCA TCGTGTTTTA GAAAAGGGAA CAGAAAAAGT AGTTCCAGAA 2340

CAGAAAAACA TTCCTCCTGA CATTTCTTTG CTGATGTCGG GCATTGGTCC ATCATCCGAT 2400

GAATATTACC CCACAGTCGT GATTACTGCT TTGATGAGTA TATTAAAAGA CCCGTCCTTA 2460

ACTATTCACC ATACTGCTGT TATTCAAGCT GTAATGTATA TATTCAAGAC CATGGGTCTC 2520

AGATGTGCCC CCTTTCTTTC CCAAATTATT CCAGAATTTA TCGCAGTTAT GAGAACGTGT 2580

CCTACGAACA TATTGGAGTT TTATTTTCAG CAACTAAGTA TTTTGGTCCT TATTGTTCGT 2640

CAGCACATAC GAAGTTTTTT ACCAGATTTA TTTAAGCTTA TCAAAGATTT TTGGAACCCG 2700

CATTCTAATT TACAATTTAC AATTTTGTCG CTAATTGAAT CACTGGCTAG AGCAATGCAG 2760

GGAGAGTTCA AGCCATACTT ACCATCTTTA TTAGTAATGA TGCTACAAAT ATTTGACTCT 2820

GATGTATCAG TGGACTCAGT CAGTACAAAA AAGGTATTGC ACGCATTCAT CGTCTTCGGT 2880

GATACATTAG CTGATTATTT TCATATGCTC TTGGATCCAA TACTTCGACT GTATGAGCGA 2940

AATGATGTTT CAATCGGTAT AAAAGAAAGT ATAATGATTA CAATTGGACG ACTTTCAATG 3000

GTTATTAATC TCTCGGAATA TGCATCAAGA ATTATACATC CTGTTATGCG TATGCTTTCG 3060

TGCAACAATG CCTCTCTCAT TCGCGTGAGT ATGGATACTG TATGTGCGCT TATATATCAA 3120

CTTAATGTTG ATTTTGCTAT TTTCATTCCA ATGATTGATA AGTGCCTTAA GATGAATGGC 3180

GTTACTCATG AAACCTACTC GATACTTGTT GAACAATTTT TACAAGAACA GCCTCTTCCT 3240

ATAAAACTCA ACCCTTATGA AAAATACGAT AAGCCTAAAT TAGATGTGGT AGCTTCCGCT 3300

GCTGATATAA CCTCTAAAAA GCTTCCTGTA AATCAAGAAA TCCTCAGAAA TGCGTGGGAA 3360

GCATCTCAAC GATCGACTAA GGATGACTGG CAAGAATGGA TCCGACGATT AGGCGTAGCT 3420

CTCTTAAGAG AATCACCTTC ACATGCCTTA CGAGCATGTG CTGCTTTGGC TGCTGCCTAT 3480

CAACCTTTAG CCAGGGACTT ATTTAACGCT AGTTTTGTTT CTTGTTGGTC TGAATTATAT 3540

GATCACTTTC AAGAAGAATT AGTTAAGTCG ATTGAGATAG CTTTAACGTC GCCACACATA 3600

TCTCCTGAAA TTATTCAGAT TTTACTCAAT CTTGCGGAAT TTATGGAGCA TGATGATAAA 3660

CCACTTCCGA TTGATATTCG TACTTTGGGT GCCTATGCAG CTAAATGCCA TGCGTTTGCT 3720

AAGGCTTTAC ATTACAAGGA GCTAGAATTC ATTGAAGAAG AATTGGTGAC AAAACCTTCG 3780

GTTGATACAA TTGAGGCCCT AATTTCAATC AATAATCAAC TCCAACAACC AGACGCAGCT 3840

ATTGGAATAC TTAAACATGC TCAGCAGCAT GACAAAATGA ATCTTAAAGA AACTTGGTAC 3900

GAAAAGTTAC AAAGGTGGGA AGATGCTCTG TCAGCTTATG AAAAAAGAGA AGCTGCTGGC 3960

GCTGGCAATT TCGAAATAAC GATGGGCAAA CTTCGTTGTT TACACGCTTT GGGTGAATGG 4020

GATCGATTAT CTCAGTTAGC TCAAGAAAAT TGGATTCATG CTGGTCATGA TGCGCGACGG 4080

TATATTGCAC CGCTTTCCGT AGCCGCTGCT TGGGGGTTAG GTCAATGGGA GCAAATGGAT 4140

GAATATATTT CTGTTATGAA GTCTGAGTCA CCAGATAAAG CTTTTTTTAA CGCGATTGTG 4200

GCTCTACATC GATCACAATT TGAAGAAGCA GCTTCTTATA TCACCAGAGC TCGAGATTTA 4260

CTTGATACTG AGCTTACTGC GCTTGTTGGT GAAAGTTATA ATAGGGCTTA CAGCGTTGCT 4320

GTCCGTGTTC AAATGTTATC CGAATTAGAA GAAATCATTA CCTATAAAAA AGCCGAGGAC 4380

AAACCCGAAG TTCGTGAAAT GATAAAGAAG ACATGGGTTA GACGTTTGAA AGGCTGTCAG 4440

AGAAATGTGG ATGTTTGGCA AAGAATGTTA AGAATACGAT CTTTAGTTAT TTCACCCCGT 4500

GATAACATGG AGATGTGGAT CAAATTCGCT AATCTCTGCA GAAAATCTGG TAGGATCAGT 4560

CTAGCGAAAA AATCACTTAA TTTACTCCTT GAAGACGACG AAAACTTAGA TAATTCACTC 4620

GTCTTAAAGA AGACTCACCC TTCAATTGTC TATGCAAATC TAAAGTTTTT GTGGGCTGTT 4680

GACGATAAAA GGAAGGCTCT TAATAGCATG CAAGAGTTTA CTTCTCAGCT AATTTCTGAC 4740

ATTAATGTTG ACCCTGCTCT TTTTGTTCAA TCTACATCAG TTAATACTCA AAAATCACAA 4800

GAAGAAATTC AATATTATTT TCATCTTCTA GCTAGATGTT ATCACAAGCA AGGTCAATGG 4860

CAGCAAGAAA TTGAGAATAA TTGGTCAGAA GGATCTTTTG ATGGAGTTCT TCAATCATAT 4920

ATGTATGCTA CGCAATTTGA TTCTAAATGG TATAAAGCTT GGCACTCTTG GGCATTAGCT 4980

AATTTCGAAG CTGTAAAGTT TTTGGAGCAA TCAGAGGAGC AAATCCCAAG TGCTGCATAT 5040

GAGCAGTATA TTATTCCAGC AGTCAAAGGC TTTTTTAAGT CAATTGCTTT AAGCAAAGGT 5100

AACCTTCAGG ACACCTTGCG CCTTCTTAAT CTTTGGTTTA AATTCGGCAA TAATAGCAAT 5160

GTAATTAATA CTTTGAACGT TGGTATATCC ACTGTGAACA TCGATATCTG GCTGGACGTT 5220

ATACCTCAGC TTATTGCGAG AATTCATGCC TCCTCTTTGA GTGTTCGTAA ATCTGTGCAT 5280

CAGTTGCTTT CCGATGTAGG TCGCGCGCAT CCCCAAGCTC TTGTTTATCC TTTAACTGTA 5340

GCAGCAAAAT CGCAGAGTTC TGCTAGGCAA AACGCTGCTT TAGCAATTAT GGATTCCTTG 5400

AAAACACATA GTCCACGTCT AGTTGAACAA GCAAGACTTG TTAGTCATGA GCTTATCAGA 5460

GCTGCAATCC TTTGGCATGA ACAATGGCAT GAAGGATTGG AAGAGGCTTC ACGATTGTAT 5520

TTTGGTGATC ATAACATTGA GGGTATGTTT GCCGTGTTGA GACCATTGCA TGAAATGTTG 5580

GAACGTGGTC CGGAAACGCT TCGTGAAATT TCTTTCCAAC AAGCCTTTGG ACGTGACTTA 5640

GTCGAAGCAA GGGATTGTTG TATCCGTTTT GAGCAAACTG GTGATATATC AGACTTAAAT 5700

CAGGCCTGGG ACTTATATTA CCAAGTTTTC AAGAAAATTC GTAAACAGCT ACCTCAGTTG 5760

ACAACATTAG ATTTACAATA CGTTTCTCCT AAACTCTTAC ATGTACATGA TCTTGAGTTA 5820

GCTGTTCCGG GAACATACGT TAGCGGGAAA CCTGTTATAA GAATTGTAAA GTTTTACCCT 5880

ACATTCAACG TGATAACATC TAAGCAACGT CCGAGACGAC TGAGTATTAA AGGCAGTGAT 5940

GGAAAAGATT ATCAATATGT TTTAAAGGGT CACGAGGACA TCAGACAAGA TGAACGTGTT 6000

ATGCAGCTAT TTGGGCTTTG TAACAATCTG TTACTAGCTG ACCCGGAAAC TTTTAAGCGC 6060

TTACTTTCAA TCCAAAGGTA TCCAGTGATT CCTTTATCAC CGGATTCAGG CCTTTTAGGC 6120

TGGGTTTTGG ATAGCGATAC TTTGCATGTC TTAATTCGTG ACTACAGAGA AAGCAGAAAG 6180

ATTTTACTCA ACATAGAACA TAGGTTGATC ATTCAGATGG CTCCAGATTA CGATCGTCTC 6240

ACTCTCCTTC AGAAAGTTGA AGTCTTTGAA TATGCCCTAC TTAGTACTAC GGGGCAGGAT 6300

TTATACCGCG TTTTATGGCT GAAGAGTCGT AGCTCAGAAG CTTGGCTTAA TAGGCGAACT 6360

AACTATTCTC GTACTCTTGC GGTGATGTCA ATGGTAGGGT ACATCTTAGG TTTGGGCGAT 6420

CGTCATCCTT CCAATTTGAT GCTGGACAGG TATACAGGTA ATATCATCCA TATCGATTTT 6480

GGAGATTGTT TTGAAGTAGC AATGCATCGA GAAAAGTTTC CCGAGAAGAT TCCTTTCCGC 6540

CTTACGCGAA TGCTTGTTAA CGCAATGGAA GTTAGTGGTA TAGAGGGGAC GTTCCGGATA 6600

ACATGCGAAC ATGTTATGCG AGTTCTTCGT ACTAATAAGG AGTCTGTGAT GGCAGTTTTA 6660

GAAGCTTTCG TTTACGATCC TCTTATTAAC TGGCGCCTTG CTCCTGCATA TTCACCTTCT 6720

ATCGATGAAA AGCAATCTAA CGAACCTAAT ACACTTCTCG GTGAGACAAT TGATGGTTTA 6780

CACCGGAAAC GCTTAAACGA AGAAGGAATT ACACTTGAAG AACGTCAAAA ACCCGAGATA 6840

CTCAATCAAA GAGCTATAAC CGTTCTTAAT CGTGTGTCCA ATAAACTTAC TGGTCGGGAT 6900

TTCAAACCCC AACAGCAATT GGATGTACCA AGTCAAGTAG AGAAGCTGAT TTTACAAGCA 6960

ACCTCTATAG AGAACCTATG CTTGTGCTAT ATTGGCTGGT GTAGTTTCTG GTAG 7014

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         i +f ++ ++++skq+p++l+++Gsdgk y+y +kg+eD rqderv+qlf+l+N+lL  d

Q: 1955  IVKFYPTFNVITSKQRPRRLSIKGSDGKDYQYVLKGHEDIRQDERVMQLFGLCNNLLLAD  2014

         5679999*****************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdl  120

         +et +r L+i++y V+pls+ sgl++wv ++++L+ l+++++e++++ll+        ++

Q: 2015  PETFKRLLSIQRYPVIPLSPDSGLLGWVLDSDTLHVLIRDYRESRKILLN-------IEH  2067

         *************************************************9.......9**

S: 121   stvqarkpklkhlkls..levfkevlenlvpkdllkklllekfpspeewfelrkaytrsl  178

         + +  ++p+++ l+l   +evf+ +l   +  + l ++l+ k+ s+e+w+++r++y r l

Q: 2068  RLIIQMAPDYDRLTLLqkVEVFEYALLS-TTGQDLYRVLWLKSRSSEAWLNRRTNYSRTL  2126

         ***********9998778*********9.5557999************************

S: 179   AvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrniv  238

         Av+s+vgyiLgLgdrh++nl++d+ tg+++hidfg +fe a+ ++k+pek+PFRLTr++v

Q: 2127  AVMSMVGYILGLGDRHPSNLMLDRYTGNIIHIDFGDCFEVAMHREKFPEKIPFRLTRMLV  2186

         ************************************************************

S: 239   nalgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk........k  286

         na++v g+eG fr++ce+v+rvlr +ke+++++Le+f+ydpl++w+

Q: 2187  NAMEVSGIEGTFRITCEHVMRVLRTNKESVMAVLEAFVYDPLINWRLapayspsiD  2242

         **********************************************9554433321

Domain Sequence
(FASTA)

IVKFYPTFNV ITSKQRPRRL SIKGSDGKDY QYVLKGHEDI RQDERVMQLF GLCNNLLLAD 60

PETFKRLLSI QRYPVIPLSP DSGLLGWVLD SDTLHVLIRD YRESRKILLN IEHRLIIQMA 120

PDYDRLTLLQ KVEVFEYALL STTGQDLYRV LWLKSRSSEA WLNRRTNYSR TLAVMSMVGY 180

ILGLGDRHPS NLMLDRYTGN IIHIDFGDCF EVAMHREKFP EKIPFRLTRM LVNAMEVSGI 240

EGTFRITCEH VMRVLRTNKE SVMAVLEAFV YDPLINWRLA PAYSPSID 288

Keyword

ATP-binding; Cell cycle; Complete proteome; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Repeat; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005829	; C:cytosol
GO:0034064	; C:Tor2-Mei2-Ste11 complex
GO:0031931	; C:TORC1 complex
GO:0016303	; F:1-phosphatidylinositol-3-kinase activity
GO:0005524	; F:ATP binding
GO:0008144	; F:drug binding
GO:0030996	; P:cell cycle arrest in response to nitrogen starvation
GO:0031670	; P:cellular response to nutrient
GO:0010507	; P:negative regulation of autophagy
GO:0010503	; P:negative regulation of cell cycle arrest in response to nitrogen starvation
GO:0010515	; P:negative regulation of induction of conjugation with cellular fusion
GO:0031929	; P:TOR signaling cascade

KEGG

spo:SPBC216.07c

;

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR024585	; DUF3385_TOR.
IPR003152	; FATC.
IPR021133	; HEAT_type_2.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR009076	; Rapamycin-bd_dom.
IPR026683	; TOR/Smg1.
IPR011990	; TPR-like_helical.

Pfam

PF11865	; DUF3385; 1.
PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08771	; Rapamycin_bind; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS50077	; HEAT_REPEAT; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013