EKS-SCP-00114

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SCP-00114

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NAK	305.7	6.9E-92	25	296	272

Status

Reviewed

Ensembl Protein

SPBC557.04.1:pep

UniProt Accession

Q9USS2;

Protein Name

Serine/threonine-protein kinase ppk29

Protein Synonyms/Alias

Gene Name

ppk29

Gene Synonyms/Alias

ppk29; SPBC557.04;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
SPBC557.04	SPBC557.04.1:pep	SPBC557.04.1

Organism

Schizosaccharomyces pombe

Functional Description

Protein Length

872

Protein Sequence
(FASTA)

MSVASFLTGE KLLAGSKFVI GKYNVTIEKY IAEGGFSHVY LVQTNSKTDG SPITAVLKRM 60

YSPDENALRF VKTEIETMEL LKSNPHVVSY IDSCIFPLEK AGVNTGFEIL LLMEYCAGGG 120

LIDFMNQRLQ TRLSEHEVLK IISDIVQGVA SLHYLRPPLI HRDLKVENVL LSFNTFKLCD 180

FGSVTEPMHA AENSSEIQAL EKSINTFTTY QYRAPEMINL YSGLGIDEKS DMWALGVLLY 240

KLCYYTTPFE TQGPNAILTA SYSFPPFPPY SHSLKNVIIA LLQPNPCLRP NIFQLMCEIC 300

RLRGTALPFR DIYSGRESSF YDLHNRKIMS LLRQTTTTPF AGNQVMPTPQ VQGSRPPPPP 360

PMPAPIYNVP NVPTVPTVSP NPFLQPTFSG TSQASAHPSI HSQSATFNNT QDVNRQSVSS 420

PKVVSSSSVT GSGASGRKVY TPQSKNPFPI SQGVTGTSSK FSASEVTEDN GSPNAGLDAD 480

NVDVEEVVNQ RYPDLNELES QLTSHTNITT SSHHNPREQE IAKLADDAFA SFRQTAGTST 540

ANSTHTTGTQ DISAFDTNFS EGVGSVRSSF DFPDRPVSRR PSSTSRSSVK ITGPSSPNAR 600

SMAYEQHSFN LDDLSNTNFG SNNSLRHAKS FSKYYSPSHK DSNKTSRNTS KEGLPSSPTM 660

LYRTTSNTRG DYIVQRTQQS ANPLTNIEPQ DMSNLSTDIN ASDVVADSTN SILYPTSTAS 720

SVANTIASDV DDFGTFNGLQ RTVSLHSERA SLDKKRPSFH DKNPYFKFSP SKYVDEGLEG 780

ESELRERVRS YANRSSSSFH NPDLTDTEIQ ETSFNNDLRP VASIQSAETS RSVSDRPANF 840

PEELNDTLFE QKYPGIVDYE EPNSNAEKNV NI 872

Nucleotide Sequence
(FASTA)

ATGTCTGTTG CATCCTTTCT CACGGGCGAA AAGCTTCTAG CAGGATCCAA GTTTGTAATT 60

GGAAAATACA ATGTTACTAT CGAAAAGTAC ATAGCCGAAG GCGGCTTTTC TCATGTATAT 120

CTTGTTCAAA CAAATTCCAA AACTGATGGA TCACCGATAA CTGCTGTTTT GAAACGCATG 180

TATTCTCCAG ACGAGAATGC CCTGCGTTTC GTGAAAACTG AAATCGAAAC GATGGAACTA 240

CTCAAATCCA ATCCCCACGT GGTTTCGTAT ATCGACTCCT GCATATTTCC TCTCGAGAAA 300

GCGGGTGTCA ACACTGGATT TGAAATCCTG CTTTTGATGG AATACTGCGC TGGGGGTGGA 360

TTGATAGATT TTATGAATCA AAGGTTACAA ACTCGGTTGT CAGAGCATGA AGTCTTAAAA 420

ATTATTTCAG ATATTGTACA GGGTGTTGCT TCCTTACACT ATCTGAGACC TCCTCTCATT 480

CATCGCGATC TGAAAGTAGA AAATGTTTTG CTAAGCTTTA ATACTTTTAA ATTGTGCGAT 540

TTTGGAAGTG TGACTGAGCC AATGCATGCT GCTGAAAACT CTAGCGAAAT TCAAGCATTA 600

GAAAAAAGTA TCAACACATT TACTACCTAC CAATATCGTG CCCCTGAGAT GATTAATTTG 660

TATTCAGGCT TAGGAATTGA TGAGAAAAGT GACATGTGGG CTTTAGGAGT CTTGTTATAC 720

AAACTCTGTT ACTATACAAC TCCTTTTGAA ACACAAGGTC CTAACGCTAT ATTAACAGCT 780

TCATATTCCT TCCCCCCATT TCCTCCTTAT TCACATTCTC TTAAAAATGT CATCATCGCT 840

TTACTTCAGC CGAATCCTTG TCTTCGTCCA AATATTTTTC AGTTGATGTG TGAGATATGT 900

CGTCTTAGAG GGACGGCTTT ACCTTTTAGG GATATATACA GTGGAAGAGA GTCGTCTTTT 960

TATGATTTGC ATAACCGGAA AATAATGTCT TTGCTTCGAC AAACAACAAC AACACCGTTT 1020

GCTGGAAACC AAGTCATGCC GACTCCACAG GTTCAGGGCT CAAGACCTCC CCCTCCTCCT 1080

CCTATGCCAG CTCCTATCTA TAACGTACCA AATGTGCCGA CTGTACCAAC CGTTTCCCCT 1140

AATCCATTTT TGCAACCTAC TTTCTCTGGC ACTTCTCAAG CTAGTGCACA TCCTTCTATC 1200

CACAGCCAAT CCGCAACATT TAACAACACT CAAGATGTGA ACAGACAGAG TGTTTCGTCT 1260

CCGAAGGTTG TTTCATCAAG TTCTGTAACT GGCTCAGGAG CTAGTGGTCG CAAAGTCTAC 1320

ACACCTCAAA GTAAGAATCC CTTCCCAATA TCTCAGGGAG TCACGGGAAC ATCTTCAAAA 1380

TTTTCTGCTA GCGAGGTTAC AGAAGATAAT GGTTCACCAA ACGCCGGACT CGATGCCGAT 1440

AACGTTGACG TTGAGGAAGT TGTTAACCAG CGTTATCCTG ATCTAAATGA GTTGGAGTCA 1500

CAGCTTACTA GTCATACTAA TATTACGACT AGTTCTCATC ATAACCCTAG GGAACAAGAG 1560

ATAGCAAAAT TGGCTGATGA TGCATTCGCT AGTTTCCGTC AGACAGCTGG TACTTCAACC 1620

GCAAATAGTA CTCATACCAC TGGTACTCAG GATATATCTG CCTTTGATAC AAATTTTTCG 1680

GAAGGGGTTG GTAGCGTAAG GTCTTCTTTT GATTTCCCTG ATCGTCCAGT ATCTAGACGA 1740

CCTTCAAGCA CTTCTAGGTC GTCTGTTAAA ATTACTGGAC CTTCGAGCCC CAATGCGCGT 1800

TCTATGGCTT ATGAGCAACA CTCCTTTAAC CTTGATGATT TGAGTAATAC TAATTTTGGT 1860

TCTAATAATT CTCTTAGACA TGCCAAATCA TTTTCCAAAT ATTATTCACC TTCTCATAAA 1920

GATTCGAACA AAACTTCCAG AAACACATCT AAAGAGGGGC TCCCCTCCAG TCCTACTATG 1980

CTCTATCGTA CAACATCTAA TACTAGAGGT GACTATATCG TTCAACGCAC ACAACAGTCT 2040

GCCAATCCTT TGACAAATAT CGAACCCCAA GATATGTCAA ACCTTAGTAC TGATATTAAT 2100

GCTTCTGACG TTGTTGCCGA TTCAACCAAC TCTATTCTTT ATCCTACTTC GACCGCGTCT 2160

TCTGTTGCCA ACACTATTGC CTCCGATGTT GACGACTTTG GAACTTTTAA TGGTTTACAA 2220

AGAACCGTGA GTTTACATAG TGAGCGGGCA AGTCTTGACA AGAAGCGTCC TTCTTTTCAT 2280

GACAAAAATC CGTACTTTAA ATTTTCTCCA AGCAAGTATG TTGACGAAGG ATTGGAAGGT 2340

GAAAGTGAAT TAAGAGAGCG TGTACGAAGT TATGCTAACC GCTCAAGTTC AAGTTTCCAT 2400

AATCCAGATT TAACAGACAC AGAAATTCAA GAGACGTCTT TTAATAACGA TTTGAGGCCT 2460

GTAGCTTCTA TTCAAAGTGC AGAAACCTCC AGAAGCGTAA GTGATAGACC TGCAAATTTT 2520

CCAGAGGAAT TAAACGACAC GTTATTTGAG CAAAAATATC CGGGAATTGT TGATTACGAG 2580

GAACCCAATT CGAATGCAGA AAAGAACGTT AATATTTGA 2619

Domain Profile

S: 1     vriekvlaeGGfalvylaedastg....ekyalKrilvneeedleeikrEieimkklsgh  56

         v+iek++aeGGf+ vyl++++s+      ++ lKr+++++e++l+ +k Eie+m  l+++

Q: 25    VTIEKYIAEGGFSHVYLVQTNSKTdgspITAVLKRMYSPDENALRFVKTEIETMELLKSN  84

         68*****************5554434548999****************************

S: 57    knivklvdssvkeekdng...skevlllleyckkgslvdllnkrlekgelseaeilkill  113

         +++v+++ds++   +++g    +e+lll+eyc  g l+d++n+rl+++ lse+e+lki++

Q: 85    PHVVSYIDSCIFPLEKAGvntGFEILLLMEYCAGGGLIDFMNQRLQTR-LSEHEVLKIIS  143

         ********998655554434489***********************99.***********

S: 114   dvtravaalHalsvpliHRDlkveNillsdegelvlcDlGSattaileveskqelsalqe  173

         d++++va+lH+l++pliHRDlkveN+lls  ++++lcD+GS+t+ ++  e+++e++al++

Q: 144   DIVQGVASLHYLRPPLIHRDLKVENVLLSF-NTFKLCDFGSVTEPMHAAENSSEIQALEK  202

         ****************************86.68***************************

S: 174   eieknttlsyrsPElidlysnlvideksDiWaLGcllYklcffesPfeesvklailngky  233

          i++ tt +yr+PE+i+lys+l ideksD+WaLG+llYklc++++Pfe  +  ail+++y

Q: 203   SINTFTTYQYRAPEMINLYSGLGIDEKSDMWALGVLLYKLCYYTTPFETQGPNAILTASY  262

         ************************************************************

S: 234   siPensryseklkslikkmlevdpeeRptiaqvl  267

         s+P+ + ys++lk++i ++l+++p  Rp+i+q++

Q: 263   SFPPFPPYSHSLKNVIIALLQPNPCLRPNIFQLM  296

         ********************************97

Domain Sequence
(FASTA)

VTIEKYIAEG GFSHVYLVQT NSKTDGSPIT AVLKRMYSPD ENALRFVKTE IETMELLKSN 60

PHVVSYIDSC IFPLEKAGVN TGFEILLLME YCAGGGLIDF MNQRLQTRLS EHEVLKIISD 120

IVQGVASLHY LRPPLIHRDL KVENVLLSFN TFKLCDFGSV TEPMHAAENS SEIQALEKSI 180

NTFTTYQYRA PEMINLYSGL GIDEKSDMWA LGVLLYKLCY YTTPFETQGP NAILTASYSF 240

PPFPPYSHSL KNVIIALLQP NPCLRPNIFQ LM 272

Keyword

ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0030479	; C:actin cortical patch
GO:0005829	; C:cytosol
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0000147	; P:actin cortical patch assembly
GO:0007015	; P:actin filament organization
GO:0065007	; P:biological regulation

KEGG

spo:SPBC557.04

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; FALSE_NEG.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013