| Tag | Content |
|---|
| EKPD ID | EPS-SCP-00004 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| PPM/PP2C | 224.5 | 4.7E-67 | 79 | 321 | 243 |
|
| Status | Reviewed |
| Ensembl Protein | SPCC4F11.02.1:pep |
| UniProt Accession | P40371; |
| Protein Name | Protein phosphatase 2C homolog 1 |
| Protein Synonyms/Alias | PP2C-1; |
| Gene Name | ptc1 |
| Gene Synonyms/Alias | ptc1; SPCC4F11.02; |
| Ensembl Information | |
| Organism | Schizosaccharomyces pombe |
| Functional Description | It has a serine and threonine phosphatase activity. Hasa specialized role in the heat shock response. May be responsible for the dephosphorylation of hsp90. Also has a role in maintaining osmotic stability. |
| Protein Length | 347 |
Protein Sequence
(FASTA) | | MKGSHPNAGS LLEPLHKLNP FSENSTSGHR KNASDHSADG ETRPIAIEMK DSKGNTVPVG 60 | | NSRPSKASNW LAGLMEDKNQ RWRRSMEDTH ICLYDFGGNQ DDGFVAVYDG HAGIQASDYC 120 | | QKNLHKVLLE KVRNEPDRLV TDLMDETFVE VNSKIAKATH NDICGCTAAV AFFRYEKNRT 180 | | RRVLYTANAG DARIVLCRDG KAIRLSYDHK GSDANESRRV TQLGGLMVQN RINGVLAVTR 240 | | ALGDTYLKEL VSAHPFTTET RIWNGHDEFF IIACDGLWDV VSDQEAVDFV RNFVSPREAA 300 | | VRLVEFALKR LSTDNITCIV VNLTRNPGDL DDSGLTADND SYSNDYY 347 |
|
Nucleotide Sequence
(FASTA) | | ATGAAGGGAA GCCATCCAAA TGCAGGTTCC CTGTTGGAAC CACTTCACAA GTTGAACCCA 60 | | TTTTCTGAAA ATTCTACAAG TGGACATCGA AAAAACGCTA GTGATCATTC GGCGGATGGA 120 | | GAAACTCGAC CGATTGCAAT TGAGATGAAG GATAGTAAAG GCAACACAGT CCCAGTTGGT 180 | | AACTCGCGCC CTAGTAAAGC CTCTAACTGG CTTGCTGGAC TGATGGAGGA TAAAAACCAA 240 | | AGATGGCGTA GGTCTATGGA GGATACTCAT ATTTGCTTGT ATGATTTTGG GGGTAATCAG 300 | | GACGACGGCT TCGTTGCCGT TTATGACGGA CATGCTGGCA TTCAAGCATC TGACTACTGT 360 | | CAGAAGAATC TTCACAAGGT ACTTTTGGAA AAGGTTAGGA ATGAGCCGGA CCGGCTGGTC 420 | | ACAGACCTAA TGGACGAAAC ATTTGTCGAG GTCAACAGCA AAATTGCAAA GGCTACTCAC 480 | | AATGACATTT GCGGTTGTAC CGCTGCAGTT GCTTTCTTTA GATATGAGAA AAACCGCACC 540 | | CGCCGTGTTC TCTACACAGC TAATGCAGGT GATGCACGTA TCGTATTATG CCGTGATGGT 600 | | AAGGCTATTC GACTTTCTTA CGATCACAAG GGATCCGATG CCAATGAGTC TCGTCGTGTG 660 | | ACCCAGTTGG GTGGTCTCAT GGTACAAAAC CGAATTAATG GCGTTCTTGC TGTCACAAGG 720 | | GCCTTAGGTG ATACCTATCT TAAGGAATTG GTCAGTGCGC ATCCCTTCAC CACTGAAACC 780 | | CGAATCTGGA ACGGTCATGA TGAGTTCTTC ATTATCGCTT GTGATGGCTT GTGGGATGTA 840 | | GTATCGGATC AGGAAGCTGT CGACTTTGTT CGCAATTTCG TAAGCCCTCG CGAAGCCGCT 900 | | GTTCGCCTGG TAGAATTTGC ATTAAAACGT CTTAGTACAG ACAATATCAC TTGTATTGTA 960 | | GTTAACTTGA CTCGCAATCC CGGTGATCTC GATGATTCAG GACTTACCGC TGATAATGAT 1020 | | TCATACAGTA ATGACTATTA TTAG 1044 |
|
| Domain Profile | S: 8 vngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheilaeeles 67 | + +r++med + +f+ +++ f++vyDGh+g +++++c+++lh++l e+++ | Q: 79 NQRWRRSMEDTHICLYDFGGNQDD----GFVAVYDGHAGIQASDYCQKNLHKVLLEKVR- 133 | 6889****************9987....6****************************88. |
| S: 68 seseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......klyvan 121 | ++ +r v++ + ++F ++ +++ +k + +d +G+ta va ++ + ly+an | Q: 134 -NEPDRLVTDLMDETFVEVNSKI----AKATHNDICGCTAAVAFFRYEknrtrrVLYTAN 188 | .89999*****************....66678888***********888888989***** |
| S: 122 vGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLavsRalGdl 181 | +Gd r+vLcr+gka++ls dHk s +E +R+ + gg ++++ R++GvLav+RalGd+ | Q: 189 AGDARIVLCRDGKAIRLSYDHKGSDANESRRVTQLGGLMVQN---RINGVLAVTRALGDT 245 | ************************************999999...*************** |
| S: 182 ylkpyvtpePevtshrl.tsedefliLasDGlwdvvsneeavslvrdvlekkeaeqeaak 240 | ylk++v++ P +t++r+ + def+i+a+DGlwdvvs++eav++vr++++ ++eaa | Q: 246 YLKELVSAHPFTTETRIwNGHDEFFIIACDGLWDVVSDQEAVDFVRNFVS----PREAAV 301 | *****************555566***************************....****** |
| S: 241 kLvklalargskdnvsaivv 260 | +Lv++al+r s+dn++ ivv | Q: 302 RLVEFALKRLSTDNITCIVV 321 | ****************9997 |
|
Domain Sequence
(FASTA) | | NQRWRRSMED THICLYDFGG NQDDGFVAVY DGHAGIQASD YCQKNLHKVL LEKVRNEPDR 60 | | LVTDLMDETF VEVNSKIAKA THNDICGCTA AVAFFRYEKN RTRRVLYTAN AGDARIVLCR 120 | | DGKAIRLSYD HKGSDANESR RVTQLGGLMV QNRINGVLAV TRALGDTYLK ELVSAHPFTT 180 | | ETRIWNGHDE FFIIACDGLW DVVSDQEAVD FVRNFVSPRE AAVRLVEFAL KRLSTDNITC 240 | | IVV 243 |
|
| Keyword | Complete proteome; Hydrolase; Magnesium; Manganese; Metal-binding; Protein phosphatase; Reference proteome; Stress response. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |