EKS-SEI-00488

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SEI-00488

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/IRAK	152.7	2.8E-44	855	1138	284

Status

Unreviewed

Ensembl Protein

Si009212m

UniProt Accession

K3Y4S4;

Protein Name

Protein Synonyms/Alias

Gene Name

Si009212m.g

Gene Synonyms/Alias

Si009212m.g;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
Si009212m.g	Si009212m	Si009212m

Organism

Setaria italica

Functional Description

Protein Length

1163

Protein Sequence
(FASTA)

MPPSRSLFLL LMLALAAARA QPPPAPPVAR TAGVRAEIDA LLAFRRGVRD PYGAMSGWDA 60

ASPSAPCSWR GVACAPGSGA SAGRVVELQL PRLRLSGPIS PALGSLPYLE RLSLRSNDLS 120

GAIPATLARV TSLRAVFLQS NSLSGPIPQS FIANLTNLDT FDVSGNLLSG PVPASFPPTL 180

KYLDLSSNAF SGTIPASISA SAPSLQFLNL SFNRLRGTVP ASLGALQNLH YLWLDGNLLE 240

GTIPAPLANC SALLHLSLQG NSLRGILPSA VAAIPTLQIL SVSRNQLTGA IPAAAFGSQR 300

NSSLRIVQLG GNQFSQVDVP GGLAADLQVV DLGGNKLAGA FPTWLTGAGG LTLLDLSGNA 360

FIGELPPAVG QLTALLELRL GGNAFTGAVP AEIGRCGALQ VLDLEDNHFS GVVPSALGGL 420

PRLREVYLGG NSFSGQIPTS LGNLSWLEAL SIPRNRLTGS LSGELFQLGN LTFLDLSENN 480

LTGEIPPAIG NLSALQSLNL SRNAFSGRIP STIGSLQNLR VLDLSGQKNL SGNVPAELFG 540

LPQLQYVSFA DNSFSGDVPE GFSSLWSLRH LNLSGNSFTG SIPATYGYLP SLQVLSASHN 600

RISGELPAEL ANCSNLTVLE ISGNQLTGSI PSDLSRLGEL EELDLSYNQL SGKIPPEISN 660

CSSLALLKLD DNRIGGDIPA SLANLSKLQT LDLSSNNLTG TIPASLAQIP VLVSFNVSHN 720

ELTGEIPVML GSRFGSPSAY ASNSDLCGPP LESECGEYRR RRRRQKVQRL ALLIGVVAAA 780

VLLLALFCCC CVLSLLRWRR RFIESRDGVK KRRRSPGRGS GSSGTSTENG VSQPKLIMFN 840

SRITYADTVE ATRQFDEENV LSRGRHGLVF KACYSDGTVL AILRLPSTSA DGAVIIEEGS 900

FRKEAESLGK VKHRNLTVLR GYYAGPPPDV RLLVYDYMPN GNLATLLQEA SHQDGHILNW 960

PMRHLIALGV SRGLAFLHQS GVVHGDVKPQ NILFDADFEP HLSDFGLEPM VVTAGAAAAA 1020

AAASTSAATP VGSLGYVAPD AAAAGQATRE GDVYSFGIVL LELLTGRRPG MFAGEEEDIV 1080

KWVKRQLQRG AVAELLEPGL LELDPESSEW EEFLLGIKVG LLCTAQDPLD RPAMGDVVFM 1140

LEGCRVGPDI PSSADPTSQP SPA 1163

Nucleotide Sequence
(FASTA)

ATGCCGCCGT CGCGGTCGCT GTTCCTGCTG CTCATGCTCG CGCTGGCCGC GGCGCGGGCG 60

CAGCCGCCCC CCGCGCCGCC GGTGGCGCGG ACGGCGGGGG TGCGGGCGGA GATCGACGCG 120

CTCCTCGCGT TCCGCCGCGG GGTGCGGGAC CCCTACGGCG CCATGTCCGG GTGGGACGCC 180

GCGTCGCCCT CGGCGCCCTG CTCCTGGCGC GGCGTCGCGT GCGCGCCCGG CTCCGGCGCC 240

TCCGCCGGCC GCGTCGTCGA GCTACAGCTC CCGCGGCTCC GCCTCTCGGG CCCCATCTCC 300

CCCGCGCTCG GCTCGCTGCC GTACCTCGAG CGGCTCAGCC TCCGCTCCAA CGACCTCTCC 360

GGCGCCATCC CGGCGACGCT GGCACGCGTC ACCTCGCTCC GCGCCGTCTT CCTCCAGTCC 420

AACTCGCTCT CCGGCCCCAT CCCCCAGTCC TTCATCGCCA ACCTCACCAA CCTCGATACC 480

TTCGACGTGT CCGGCAACCT CCTGTCCGGG CCCGTCCCCG CTTCATTTCC TCCCACCTTG 540

AAGTACCTCG ACCTCTCCTC CAATGCCTTC TCCGGCACCA TCCCGGCGAG CATTAGCGCC 600

TCGGCGCCGA GCCTCCAGTT CCTCAACCTA TCCTTCAACC GACTCCGGGG CACCGTGCCG 660

GCGTCGCTGG GCGCCTTGCA GAACCTGCAT TACCTCTGGC TCGACGGGAA CCTCCTCGAG 720

GGGACCATCC CTGCGCCGCT CGCCAACTGC TCGGCGCTGC TCCACCTGAG CCTGCAGGGG 780

AACTCGCTCC GCGGCATCCT GCCGTCCGCG GTCGCCGCCA TACCCACGCT GCAGATTCTC 840

TCGGTGTCGC GGAACCAGCT CACCGGCGCC ATCCCGGCCG CGGCGTTCGG CAGCCAGAGG 900

AACTCGTCTC TGCGCATCGT GCAGCTTGGC GGCAACCAGT TCTCCCAGGT GGACGTGCCG 960

GGAGGGCTCG CCGCGGATCT CCAGGTGGTG GACCTGGGTG GCAACAAGCT GGCTGGCGCG 1020

TTCCCGACCT GGCTCACCGG GGCGGGGGGA CTGACGCTGC TCGACCTCTC CGGCAATGCG 1080

TTCATCGGCG AGTTGCCGCC GGCGGTCGGG CAGCTCACTG CACTGCTGGA GCTGCGCCTT 1140

GGTGGCAATG CTTTCACTGG TGCCGTGCCT GCGGAGATTG GCAGATGCGG CGCACTCCAG 1200

GTGCTTGATC TCGAGGACAA CCACTTCTCC GGCGTGGTGC CATCGGCTCT TGGCGGTCTC 1260

CCAAGGCTCA GAGAGGTCTA TCTCGGTGGG AACTCTTTCT CCGGCCAGAT TCCGACGAGC 1320

TTGGGGAATC TGTCATGGCT CGAGGCATTG TCCATACCGA GGAACAGACT CACTGGTAGC 1380

CTTTCTGGTG AGCTCTTCCA GCTGGGAAAC CTGACGTTCT TGGACCTATC TGAGAACAAC 1440

CTCACCGGAG AGATCCCTCC GGCCATTGGT AATCTATCTG CTCTTCAGAG TTTGAATTTG 1500

AGCCGCAATG CCTTCTCTGG CCGCATTCCA TCGACCATTG GCAGCCTGCA GAACCTGCGA 1560

GTTCTTGACC TCTCTGGTCA GAAGAACCTC TCTGGCAATG TCCCAGCAGA GCTTTTTGGC 1620

TTGCCGCAGC TGCAATATGT GTCGTTTGCC GACAACTCGT TCTCTGGGGA TGTTCCTGAA 1680

GGATTCAGCA GTCTTTGGAG CCTGAGGCAT CTCAACCTCT CCGGCAATTC TTTCACTGGG 1740

TCGATCCCGG CAACATATGG GTACCTGCCA TCGCTTCAAG TGCTCTCAGC CTCGCACAAC 1800

CGCATTTCTG GGGAGCTTCC TGCCGAGCTC GCCAATTGTT CCAACCTCAC TGTGCTTGAA 1860

ATCAGTGGCA ACCAGCTGAC TGGCTCCATC CCGAGTGACC TCTCACGCCT TGGTGAATTG 1920

GAGGAGCTTG ACCTCAGCTA CAATCAGCTT TCAGGCAAGA TACCACCAGA GATTTCCAAC 1980

TGCTCGTCGC TTGCCCTTCT CAAGCTTGAT GACAATCGTA TTGGCGGTGA CATACCAGCC 2040

TCCCTTGCCA ACCTCTCGAA GCTGCAGACA CTTGACCTGT CATCCAACAA TCTTACCGGC 2100

ACCATCCCTG CTTCATTGGC TCAGATTCCA GTCCTTGTAT CATTCAATGT GTCACACAAT 2160

GAGCTTACTG GTGAGATACC AGTAATGCTT GGCTCCCGCT TTGGCTCCCC TTCAGCATAT 2220

GCTTCAAACT CAGATTTGTG CGGTCCACCA TTGGAGAGCG AATGTGGTGA GTACAGGCGA 2280

CGCCGGAGGC GACAGAAGGT GCAGCGCCTT GCTCTGCTAA TTGGTGTAGT GGCTGCTGCA 2340

GTGCTGCTCC TTGCGCTGTT CTGCTGTTGC TGCGTGTTAA GCTTGCTGCG ATGGAGGCGC 2400

AGGTTCATTG AGAGCCGTGA TGGTGTCAAG AAGAGGAGAC GCAGCCCTGG ACGTGGCAGC 2460

GGGTCGAGTG GCACAAGCAC GGAGAATGGT GTCAGCCAGC CGAAGTTGAT CATGTTCAAC 2520

TCAAGGATCA CCTATGCTGA CACGGTTGAG GCGACACGGC AGTTTGACGA GGAGAATGTG 2580

CTCAGCCGAG GCCGTCATGG TCTCGTGTTC AAGGCTTGTT ACAGTGATGG CACCGTGCTG 2640

GCCATTTTGC GGCTTCCGTC CACCTCTGCC GATGGTGCTG TGATTATTGA AGAGGGCTCA 2700

TTCAGAAAAG AGGCAGAGTC TCTTGGCAAG GTGAAGCACA GGAACCTCAC TGTGCTCCGT 2760

GGCTACTACG CCGGGCCGCC GCCGGATGTT CGTCTGCTGG TCTATGACTA CATGCCCAAC 2820

GGCAACCTCG CCACATTGCT CCAGGAAGCA TCTCACCAAG ATGGCCACAT CCTCAACTGG 2880

CCGATGAGGC ACCTAATTGC GCTCGGGGTC TCCCGCGGCC TCGCGTTCCT GCACCAGTCC 2940

GGCGTCGTGC ACGGCGACGT CAAGCCACAG AACATCCTAT TCGACGCCGA CTTCGAGCCG 3000

CACCTGTCTG ACTTTGGCCT CGAGCCCATG GTGGTGACCG CGGGCGCTGC TGCAGCAGCC 3060

GCCGCCGCAT CGACATCAGC CGCGACGCCA GTGGGCTCGC TCGGCTACGT CGCCCCCGAC 3120

GCGGCTGCCG CCGGGCAGGC CACGAGGGAA GGCGATGTGT ACAGCTTCGG CATCGTCTTA 3180

CTGGAGCTCC TCACCGGGCG GCGTCCCGGC ATGTTCGCCG GGGAGGAGGA GGACATCGTG 3240

AAGTGGGTGA AGCGTCAGCT GCAGCGCGGC GCGGTGGCAG AGCTGCTGGA GCCGGGCCTG 3300

CTGGAGCTGG ACCCGGAGTC CTCCGAGTGG GAGGAGTTCC TGCTGGGCAT CAAGGTCGGG 3360

CTGCTCTGCA CCGCGCAGGA CCCGCTGGAC CGCCCGGCCA TGGGCGACGT GGTGTTCATG 3420

CTGGAGGGCT GCCGCGTCGG CCCGGACATC CCGTCCTCCG CCGACCCCAC CTCCCAGCCG 3480

TCGCCGGCGT AG 3492

Domain Profile

S: 1     fsednrigeGgfgevyrgelk.ntavavkklkee.adlslkelkqsfltElkvlarfrHd  58

         f+e+n++++G  g v++++   +t++a+ +l ++ ad  +   + sf +E + l +++H

Q: 855   FDEENVLSRGRHGLVFKACYSdGTVLAILRLPSTsADGAVIIEEGSFRKEAESLGKVKHR  914

         789***************97626789*****865156666677789**************

S: 59    nilellgysaes..eklcLvYqymknGsLedrLqcq..kgsepLsWpqRlsillGtarai  114

         n+  l gy a    +   LvY ym+nG L   Lq    ++ + L Wp+R  i+lG++r++

Q: 915   NLTVLRGYYAGPppDVRLLVYDYMPNGNLATLLQEAshQDGHILNWPMRHLIALGVSRGL  974

         *********985337889***************965348899******************

S: 115   efLHeaspslihgdiksaNiLLDekltpKlgDfglar...fapesekqsstvlrtskvrg  171

          fLH+    ++hgd+k+ NiL D +++p l+Dfgl     +a+++++ + + + + + +g

Q: 975   AFLHQS--GVVHGDVKPQNILFDADFEPHLSDFGLEPmvvTAGAAAAAAAASTSAATPVG  1032

         ******..9*************************9775435666666666667777889*

S: 172   tlaYlpeefirvgqltvkvDvySfGiVllEvltGlravdedrktkyLkdllkeeieeekv  231

         +l Y+++++   gq t + DvySfGiVllE+ltG+r      +++ ++  +k ++++  v

Q: 1033  SLGYVAPDAAAAGQATREGDVYSFGIVLLELLTGRRPGMFAGEEEDIVKWVKRQLQRGAV  1092

         ************************************955555556666677777766554

S: 232   .eilek.fldkkagkleeellealielalaclaekakkrPtmsqvl  275

          e+le   l+  + + e e     i+++l c+a++   rP m +v+

Q: 1093  aELLEPgLLELDPESSEWEEFLLGIKVGLLCTAQDPLDRPAMGDVV  1138

         255554244445555555555666899***************9997

Domain Sequence
(FASTA)

FDEENVLSRG RHGLVFKACY SDGTVLAILR LPSTSADGAV IIEEGSFRKE AESLGKVKHR 60

NLTVLRGYYA GPPPDVRLLV YDYMPNGNLA TLLQEASHQD GHILNWPMRH LIALGVSRGL 120

AFLHQSGVVH GDVKPQNILF DADFEPHLSD FGLEPMVVTA GAAAAAAAAS TSAATPVGSL 180

GYVAPDAAAA GQATREGDVY SFGIVLLELL TGRRPGMFAG EEEDIVKWVK RQLQRGAVAE 240

LLEPGLLELD PESSEWEEFL LGIKVGLLCT AQDPLDRPAM GDVV 284

Keyword

ATP-binding; Leucine-rich repeat; Nucleotide-binding; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Arabidopsis lyrata"; ?>Arabidopsis thaliana"; ?>Brassica rapa"; ?>Glycine max"; ?>Hordeum vulgare"; ?>Musa acuminata"; ?>Oryza brachyantha"; ?>Oryza glaberrima"; ?>Oryza indica"; ?>Oryza sativa"; ?>Populus trichocarpa"; ?>Selaginella moellendorffii"; ?>Solanum lycopersicum"; ?>Solanum tuberosum"; ?>Sorghum bicolor"; ?>Vitis vinifera"; ?>Zea mays"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR001611	; Leu-rich_rpt.
IPR025875	; Leu-rich_rpt_4.
IPR013210	; LRR-contain_N2.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00560	; LRR_1; 4.
PF12799	; LRR_4; 2.
PF08263	; LRRNT_2; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS51450	; LRR; 16.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013