EPS-SEI-00091

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-SEI-00091

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	137.8	1.1E-39	122	390	269

Status

Unreviewed

Ensembl Protein

Si016182m

UniProt Accession

K3YPH4;

Protein Name

Protein Synonyms/Alias

Gene Name

Si016166m.g

Gene Synonyms/Alias

Si016166m.g;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
Si016166m.g	Si016182m	Si016182m
Si016166m.g	Si016166m	Si016166m

Organism

Setaria italica

Functional Description

Protein Length

1043

Protein Sequence
(FASTA)

MGCSASKCCS QLKCSLCSSG CLGQTPDSPR ESRGKLSRGR GKGIGGSDDS SDDLGEDDDS 60

LNQMNTREST VGISRLSRVS SQFLPPDGSR KVQVPLGNYD LRYSFLSQRG YYPESLDKPN 120

QDSYCIHTPF GASPDDHFFG VFDGHGEYGA QCSQFVKRRL CENLLRDNRF RTDAVLALHS 180

AFVATNSQLH DDNLDDSMSG TTAITILVRG KTIYVANTGD SRAVIAEKRG DNIVAVDLSI 240

DQTPYRFDEL ERVKECGARV LTLDQIEGLK NPDVQCWGTE ESDDGDPPRL WVQNGMYPGT 300

AFTRSIGDSV AESIGVIADP EIFVLDLNSK NPFFVLASDG VFEFLSSQTV VDMISKYKDP 360

RDACAEIVAE SYRLWLQYET RTDDITIIVV HINGLTDVES TQTVTKVSLQ PSPQVVGLAC 420

SESPLIVSSN TNNQRSRHDL SRARLRALES SLENGQLWVP SSPSHRKTWE EQAHIERVLH 480

DHFLFRKITD SQCHVLLDCM QRVEVKPGDI VVQQGGDGDC FYVVGSGEYE VLAIQEEEGK 540

ETTKVLHRYT ADKLSSFGEL ALMHNKPLQA SVRAVTSGTL WALKREDFRG ILMSEFSNIA 600

SLKLLRSVEL FTRFTVLQLS QLAESLVEVS FADGQTIVDK AQSSQENGNY VVEIGEGGHF 660

GEWTLIGETI TFTAIAVGDV TCSTIAKEKF DTIVGPLPKL SQADSRIKES LVTKENVADD 720

DFPFRRVQLS DLEWKMCIYA AECSEIGLVR IRGSDKIRSL KRFYIKRVQD LHKEVQVFEE 780

KELMKSLSQS TCVPEVLCTC ADQSYLGILL NCCLCCSLAS ILHTPLNESS AKFFAASVVV 840

ALEELHQKSI IYRGVSADIL MLDRSGHLQL VDFRFAKKIE GERTYTTCGI ADSLAPEIVL 900

GRGHGFPADW WALGVLIYFM LQSDMPFGSW RESELEPVSK IAKGHLVMPL IFSAEVIDLI 960

TKLLVVDENV RLGTSGAGAV KKHPWFDGID WEQIASGTYT VPDEITERMD SCIETLNEDL 1020

TASPSVPIED PDDLTAPEWI QDW 1043

Nucleotide Sequence
(FASTA)

ATGGGCTGTT CAGCTTCCAA GTGTTGTTCA CAACTGAAGT GCTCTTTGTG CTCAAGTGGG 60

TGCCTTGGGC AGACACCTGA CTCCCCAAGA GAATCAAGGG GAAAGTTAAG CCGGGGGAGG 120

GGAAAGGGAA TCGGTGGTTC AGATGACTCT TCTGATGATC TCGGGGAAGA CGACGACTCG 180

TTGAACCAAA TGAACACAAG GGAATCAACT GTTGGCATCA GTCGACTATC AAGGGTCTCA 240

TCACAGTTTC TTCCTCCTGA TGGTTCGCGC AAAGTTCAGG TCCCTTTGGG TAACTATGAC 300

CTGAGATACT CCTTCTTGTC TCAAAGAGGT TACTATCCAG AATCACTGGA CAAGCCAAAC 360

CAAGATAGCT ACTGCATACA TACCCCATTT GGAGCAAGTC CTGATGACCA CTTCTTTGGT 420

GTGTTTGATG GTCATGGAGA GTATGGAGCC CAGTGCTCAC AGTTTGTGAA GCGAAGATTA 480

TGTGAGAACC TGCTCAGAGA TAATCGCTTC CGTACAGATG CTGTGCTAGC TCTTCATTCT 540

GCTTTTGTGG CAACAAACTC GCAGCTTCAT GATGACAACT TGGATGACTC CATGAGTGGT 600

ACTACAGCAA TCACTATATT GGTCAGGGGT AAAACTATAT ACGTTGCAAA TACTGGCGAT 660

TCACGTGCTG TTATTGCTGA AAAACGAGGG GACAATATTG TTGCTGTTGA TCTCTCCATA 720

GATCAAACTC CTTACCGGTT TGATGAGCTT GAAAGGGTCA AGGAATGTGG TGCTAGAGTT 780

CTGACCTTGG ATCAAATAGA GGGGCTAAAG AACCCAGATG TGCAGTGTTG GGGTACTGAA 840

GAAAGTGATG ATGGTGATCC TCCAAGGCTA TGGGTGCAAA ATGGCATGTA CCCAGGAACT 900

GCTTTTACAC GTAGCATTGG AGATTCTGTT GCTGAGTCCA TTGGTGTCAT TGCAGATCCC 960

GAGATTTTTG TTCTGGATCT CAATTCCAAA AATCCATTTT TTGTTCTTGC TAGTGATGGA 1020

GTATTTGAGT TCCTTTCCAG TCAAACAGTT GTCGACATGA TTTCTAAATA CAAGGATCCT 1080

CGAGATGCAT GTGCAGAAAT TGTTGCTGAG TCCTATCGTC TTTGGCTACA GTATGAAACT 1140

CGCACAGATG ATATTACAAT CATAGTTGTG CATATTAATG GGTTAACTGA TGTGGAATCT 1200

ACCCAGACTG TTACAAAAGT GTCTTTACAG CCTTCACCAC AAGTAGTAGG ACTGGCATGC 1260

TCCGAATCAC CACTAATAGT AAGTTCCAAC ACAAACAATC AGCGTTCCAG ACATGATTTA 1320

TCACGCGCAA GATTGAGGGC TCTTGAAAGT TCTCTAGAAA ATGGCCAATT ATGGGTCCCA 1380

TCATCTCCAT CTCATCGAAA GACATGGGAA GAACAAGCGC ATATTGAGCG GGTACTACAT 1440

GATCATTTCC TCTTCAGAAA GATTACTGAC TCGCAATGTC ATGTTCTACT TGATTGTATG 1500

CAACGGGTTG AGGTGAAACC TGGGGATATA GTAGTGCAGC AGGGTGGCGA TGGTGACTGC 1560

TTCTATGTAG TTGGTAGTGG TGAGTATGAA GTTCTGGCCA TTCAGGAAGA AGAAGGAAAG 1620

GAAACAACCA AGGTTCTGCA TCGGTATACA GCAGACAAGC TATCTTCCTT TGGGGAGCTA 1680

GCACTGATGC ACAATAAGCC ACTTCAAGCT TCTGTTCGTG CTGTGACCAG TGGAACATTA 1740

TGGGCTCTAA AGAGGGAGGA TTTCCGGGGA ATTCTGATGT CAGAATTTTC AAACATTGCA 1800

TCATTGAAGT TGCTCCGATC AGTAGAGCTG TTTACAAGAT TTACAGTGCT TCAACTAAGT 1860

CAACTTGCTG AGTCACTTGT TGAAGTATCT TTTGCAGATG GTCAAACAAT AGTAGACAAG 1920

GCACAAAGCA GTCAAGAAAA TGGTAATTAT GTGGTTGAGA TAGGTGAGGG AGGACACTTC 1980

GGTGAATGGA CTCTCATTGG TGAAACCATT ACGTTCACTG CTATTGCAGT TGGTGATGTG 2040

ACTTGTTCTA CTATTGCAAA GGAGAAATTT GATACAATTG TTGGGCCTTT GCCTAAACTT 2100

TCACAAGCTG ATTCCAGGAT TAAAGAATCT CTGGTCACTA AGGAGAATGT TGCAGATGAT 2160

GACTTCCCCT TTAGGAGAGT GCAGCTATCT GATTTGGAAT GGAAAATGTG CATATATGCT 2220

GCTGAGTGCA GTGAGATTGG TCTCGTCCGA ATCAGGGGCT CTGACAAGAT CAGAAGTTTA 2280

AAGAGGTTTT ACATCAAGAG AGTACAGGAT CTCCATAAGG AAGTACAAGT CTTTGAGGAA 2340

AAGGAACTTA TGAAAAGCTT GAGCCAATCA ACTTGTGTGC CAGAAGTCCT ATGTACTTGT 2400

GCTGATCAGT CATACCTTGG GATATTGCTG AATTGCTGCC TTTGTTGCTC ACTGGCTTCA 2460

ATACTTCACA CACCACTAAA TGAATCATCT GCAAAATTCT TTGCAGCCTC AGTTGTTGTT 2520

GCTCTAGAAG AACTTCATCA GAAGTCCATT ATTTATAGAG GTGTTTCGGC AGACATTCTT 2580

ATGCTTGACA GATCAGGTCA TCTGCAACTG GTTGATTTTA GGTTTGCAAA GAAAATAGAA 2640

GGTGAAAGGA CATACACAAC ATGTGGGATT GCTGACTCTC TAGCACCAGA GATAGTTCTT 2700

GGTAGGGGCC ATGGATTTCC TGCTGACTGG TGGGCCCTTG GAGTCTTGAT CTATTTCATG 2760

CTGCAGTCTG ACATGCCATT CGGTTCCTGG AGGGAGAGCG AACTGGAACC TGTTTCAAAA 2820

ATTGCCAAAG GCCACCTTGT TATGCCATTG ATATTCAGTG CGGAAGTTAT TGACCTTATA 2880

ACCAAGCTAC TTGTGGTAGA TGAAAATGTG CGCCTCGGAA CCAGTGGTGC CGGAGCTGTG 2940

AAGAAACATC CCTGGTTTGA TGGCATTGAC TGGGAACAAA TAGCATCTGG GACTTACACA 3000

GTACCTGATG AAATCACTGA GCGGATGGAC AGCTGTATAG AAACTCTTAA CGAGGACTTA 3060

ACAGCGTCTC CTTCTGTGCC AATTGAAGAC CCAGATGATC TTACTGCTCC AGAATGGATC 3120

CAAGATTGGT AA 3132

Domain Profile

S: 17    davtsspnflkspekkdrlaffgvyDGhggsevakfcseklheilaeelesseseerkvk  76

         d+  +++ f++sp+     +ffgv+DGhg  e   +cs+ +++ l e+l   ++ +++

Q: 122   DSYCIHTPFGASPDD----HFFGVFDGHG--EYGAQCSQFVKRRLCENLLRDNRFRTDAV  175

         555566777777775....8********9..66777777777777777775556677777

S: 77    kalakaFlstdeelkvleeksldidksGstavvalikdsklyvanvGdSravLcrng.k.  134

          al +aF +t ++l   ++ +ld + sG+ta ++l++++++yvan+GdSrav++ ++ +

Q: 176   LALHSAFVATNSQL---HDDNLDDSMSGTTAITILVRGKTIYVANTGDSRAVIAEKRgDn  232

         89************...777799999*****************************66347

S: 135   ..avelssdHkpsredEleRieeaggsvilkdgaRv........................  168

           av ls d +p r dEleR++e g++v   d   +

Q: 233   ivAVDLSIDQTPYRFDELERVKECGARVLTLD--QIeglknpdvqcwgteesddgdpprl  290

         99***************************999..7788899*******************

S: 169   ......lGvLavsRalGdlylkpy.vtpePevtshrltsedefliLasDGlwdvvsneea  221

                + +a +R++Gd   +++ v+++Pe+++ +l+s++ f++LasDG+++ +s++++

Q: 291   wvqngmYPGTAFTRSIGDSVAESIgVIADPEIFVLDLNSKNPFFVLASDGVFEFLSSQTV  350

         ***9987779************888***********************************

S: 222   vslvrdvlekkeaeqeaakkLvklalargsk.dnvsaivv  260

         v+++ ++ +  +a+ e+  +  +l l+++++ d++++ivv

Q: 351   VDMISKYKDPRDACAEIVAESYRLWLQYETRtDDITIIVV  390

         *********5555555444444454554443588888886

Domain Sequence
(FASTA)

DSYCIHTPFG ASPDDHFFGV FDGHGEYGAQ CSQFVKRRLC ENLLRDNRFR TDAVLALHSA 60

FVATNSQLHD DNLDDSMSGT TAITILVRGK TIYVANTGDS RAVIAEKRGD NIVAVDLSID 120

QTPYRFDELE RVKECGARVL TLDQIEGLKN PDVQCWGTEE SDDGDPPRLW VQNGMYPGTA 180

FTRSIGDSVA ESIGVIADPE IFVLDLNSKN PFFVLASDGV FEFLSSQTVV DMISKYKDPR 240

DACAEIVAES YRLWLQYETR TDDITIIVV 269

Keyword

Hydrolase; Magnesium; Metal-binding; Protein phosphatase.

Sequence Source

Ensembl

Orthology

Ortholog group

Arabidopsis lyrata"; ?>Arabidopsis thaliana"; ?>Brachypodium distachyon"; ?>Brassica rapa"; ?>Chlamydomonas reinhardtii"; ?>Glycine max"; ?>Hordeum vulgare"; ?>Musa acuminata"; ?>Oryza brachyantha"; ?>Oryza glaberrima"; ?>Oryza indica"; ?>Oryza sativa"; ?>Physcomitrella patens"; ?>Populus trichocarpa"; ?>Selaginella moellendorffii"; ?>Solanum lycopersicum"; ?>Solanum tuberosum"; ?>Sorghum bicolor"; ?>Vitis vinifera"; ?>Zea mays"; ?>

Gene Ontology

GO:0005952	; C:cAMP-dependent protein kinase complex
GO:0005524	; F:ATP binding
GO:0008603	; F:cAMP-dependent protein kinase regulator activity
GO:0004672	; F:protein kinase activity
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR002373	; cAMP/cGMP_kin.
IPR018490	; cNMP-bd-like.
IPR000595	; cNMP-bd_dom.
IPR011009	; Kinase-like_dom.
IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR000719	; Prot_kinase_cat_dom.
IPR015655	; Protein_Pase_2C.
IPR014710	; RmlC-like_jellyroll.

Pfam

PF00027	; cNMP_binding; 2.
PF00069	; Pkinase; 1.
PF00481	; PP2C; 1.

SMARTs

SM00100	; cNMP; 2.
SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS50042	; CNMP_BINDING_3; 2.
PS01032	; PP2C; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

PR00103

; CAMPKINASE.

Created Date

20-Feb-2013