EKS-SEI-00470

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SEI-00470

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/IRAK	170.6	9.9E-50	821	1086	266

Status

Unreviewed

Ensembl Protein

Si028758m

UniProt Accession

K3ZQ78;

Protein Name

Protein Synonyms/Alias

Gene Name

Si028758m.g

Gene Synonyms/Alias

Si028758m.g;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
Si028758m.g	Si028758m	Si028758m

Organism

Setaria italica

Functional Description

Protein Length

1101

Protein Sequence
(FASTA)

MSPLLLGFLG LLLVAGEVVV IAGAQGGAGS AGDDREVLVE LKRFLQENNR VNRGAYDTWS 60

ESDASPCGWQ GVGCDAAGRV ASLDLSRASI SGPAFGNFSR LPALASLDLS DNTISGAGDI 120

GQCRGLVHLN ISHNLIYGSL DISGLTMLQT LDVSGNRLVG GIAANFTAIC ADLAVFNVST 180

NRLTGNITGM FDGCARLEYV DLSSNNFTGE LWPGITRFRQ FNAAENNLTG SVPPATFPVG 240

CKLESLDLSA NKLTGSFPDS IAKCGNLTYL SLWGNGFNGV IPAGLGNLTV IETIILGKNS 300

FDRRIPPELT NCTKLQFLDI SKNMFGGNVQ DTFGRFASLR YLVLHHNNYT GGIVTSGVLR 360

LPLLARLDLS FNEFSGELPP ELADMKSLKY LMLAYNQFSG SIPPAYGRLA ELQALDLSYN 420

QLSSGIPETV GNLTSLLWLM LAGNRLSGQI PPEIGKCTSL LWLNLADNEL TGKIPPEMAA 480

IGTNPGPTFA KNRKDTAVLA GSGECQAMKR WIPASYPPFS FVYSIMTREN CRSIWDRILK 540

GYGIVPICTN SSSPVRSNTI SGYVQLSGNR LSGEIPPEIG AMRNLSLLHL DNNRLTGRLP 600

TEISRLPLVV LNVSRNIISG AIPSEIGRIR CLEMMDLSYN NFSGELPGSL SQLTELNRFN 660

VSYNPLLYGN VPTTGQFGTF DEQSFLGDPL ISFPRGAGKQ PPPEAADAPA VRGRGMSPKT 720

IAVWFLFSLL VAFVAGALVF FMANLRARFP VDQEPDPESF SCENPKCGSG KCSLQLSTSS 780

PPSGSSSSSS TGCSSAEGVK VFQLCKTAFT YRDIVSATSN FSDDLVIGRG GYGVVYRGVL 840

PDGRTVAVKR LARPRDGDCE REFRAEMEVL ADRMGSAWPH PNLVTLYGWC LSGSAKILVY 900

EYLDGGNLEA LIPDTAAFGW ARRLDTAIGV ARALVFLHHE CRPAVVHRDV KASNVLLDRD 960

GRAKVTDFGL ARVVRPGDTH VSTVVAGTVG YVAPEYGQTW RATTKGDVYS YGVLLMELAT 1020

GRRAVDGGEE ECLVEWARRM DKEGWRSRKE AAAAGGTVSW ELLTLGMRCT ADAPPERPDM 1080

LEVLAALVDV AKAAGVRLEF T 1101

Nucleotide Sequence
(FASTA)

ATGTCTCCCC TGCTCCTCGG ATTCCTCGGC TTACTCCTCG TCGCAGGTGA GGTGGTGGTG 60

ATAGCCGGAG CGCAGGGCGG AGCCGGTAGC GCCGGCGACG ACAGGGAGGT GCTCGTTGAG 120

CTCAAGCGCT TCCTGCAGGA GAACAACAGG GTGAACCGCG GCGCCTACGA CACGTGGTCA 180

GAATCGGATG CGTCGCCGTG CGGGTGGCAA GGCGTGGGCT GCGACGCCGC CGGCCGCGTC 240

GCGTCGCTTG ACCTGTCCCG CGCGAGCATC TCCGGCCCGG CGTTCGGCAA CTTCTCGCGG 300

CTGCCCGCGC TCGCCAGCCT CGACCTCTCC GACAACACCA TCAGCGGCGC TGGCGACATC 360

GGCCAATGCC GCGGCCTCGT GCACCTCAAC ATCTCCCACA ACCTCATCTA CGGCTCGCTG 420

GACATCTCCG GCCTGACAAT GCTGCAGACG CTCGACGTGT CGGGGAACCG CCTCGTGGGC 480

GGCATCGCGG CGAACTTCAC GGCGATCTGC GCCGACCTGG CCGTCTTCAA CGTCTCCACC 540

AATCGGCTCA CCGGCAATAT CACCGGCATG TTCGACGGCT GCGCCAGGCT CGAGTACGTC 600

GACCTCAGCT CCAACAACTT CACCGGCGAG CTGTGGCCGG GCATCACGAG GTTCAGGCAG 660

TTCAACGCCG CCGAGAATAA TCTGACCGGG AGCGTCCCGC CGGCCACGTT CCCGGTCGGC 720

TGCAAGCTCG AATCTTTGGA CCTGTCAGCG AACAAGCTGA CTGGAAGCTT CCCGGACTCC 780

ATAGCCAAGT GTGGGAACCT GACGTACTTG TCGCTGTGGG GGAATGGCTT CAACGGCGTC 840

ATACCGGCCG GATTGGGGAA CCTCACCGTG ATCGAGACAA TAATTCTCGG GAAGAACAGC 900

TTCGACCGTC GGATACCGCC GGAGCTGACC AACTGCACTA AGCTTCAGTT CTTGGACATA 960

AGCAAAAACA TGTTTGGAGG GAACGTGCAA GACACCTTTG GCAGGTTTGC GAGCTTGAGG 1020

TACCTTGTGC TACACCACAA CAACTACACC GGCGGCATCG TCACCTCCGG CGTGCTCCGG 1080

CTACCGCTGC TAGCCAGGCT CGACCTCAGC TTCAACGAGT TCTCCGGCGA GCTCCCTCCA 1140

GAGTTGGCCG ACATGAAGAG CCTCAAGTAC CTGATGCTCG CCTACAACCA ATTCTCCGGA 1200

AGCATACCGC CGGCGTACGG CCGGCTCGCC GAGCTCCAGG CACTGGACCT GTCTTACAAT 1260

CAGCTATCCA GCGGGATACC GGAAACCGTG GGGAACCTGA CGTCGCTTTT GTGGCTGATG 1320

CTCGCGGGGA ACCGGCTCTC TGGACAGATT CCGCCGGAAA TTGGCAAATG CACCAGCTTG 1380

CTCTGGCTGA ACCTGGCCGA CAACGAGTTG ACCGGGAAGA TCCCGCCGGA GATGGCAGCG 1440

ATAGGGACCA ACCCCGGCCC TACGTTCGCC AAGAACAGGA AAGATACAGC CGTGCTCGCC 1500

GGCTCCGGCG AGTGCCAGGC CATGAAGCGC TGGATCCCGG CGAGCTATCC CCCGTTCAGC 1560

TTCGTGTACT CGATCATGAC GCGGGAGAAC TGCCGCAGCA TATGGGACCG GATCCTCAAG 1620

GGCTACGGCA TCGTCCCCAT CTGCACCAAC TCTTCGTCGC CGGTGAGGTC CAACACGATC 1680

TCCGGATACG TGCAGCTGTC CGGTAACCGG CTGTCCGGAG AGATACCGCC AGAGATCGGG 1740

GCGATGCGGA ACCTCAGCCT GCTCCACCTC GACAACAACC GGCTCACCGG GCGGCTGCCG 1800

ACAGAGATCA GCCGGCTTCC TCTCGTCGTG CTGAACGTCT CGCGGAACAT CATCTCAGGC 1860

GCGATCCCGT CGGAGATCGG CCGCATTCGG TGCCTCGAGA TGATGGACCT GTCCTACAAC 1920

AACTTCTCCG GCGAGCTGCC GGGGAGCCTG AGCCAGCTCA CGGAGCTGAA CAGGTTCAAC 1980

GTGTCCTACA ACCCACTTCT TTACGGTAAC GTCCCGACCA CCGGCCAGTT CGGCACCTTC 2040

GACGAGCAGT CCTTCCTCGG CGACCCACTC ATCTCATTCC CGCGTGGCGC CGGCAAGCAA 2100

CCACCACCGG AAGCTGCGGA TGCTCCCGCC GTTCGAGGAC GCGGCATGTC TCCAAAAACC 2160

ATTGCGGTGT GGTTCCTGTT CTCACTCCTC GTCGCCTTCG TCGCCGGCGC CTTGGTGTTT 2220

TTCATGGCAA ATCTCCGCGC ACGGTTCCCC GTCGACCAGG AGCCGGACCC GGAGTCATTC 2280

TCGTGCGAGA ACCCCAAGTG CGGCTCCGGC AAGTGCTCCT TGCAGCTGTC AACTTCGTCG 2340

CCGCCGTCCG GGTCATCGTC GTCGTCGTCC ACCGGGTGCT CCTCCGCAGA GGGAGTGAAG 2400

GTGTTCCAGC TCTGCAAGAC GGCGTTCACC TACCGCGACA TCGTGTCGGC CACGAGCAAC 2460

TTCTCCGACG ACCTGGTGAT CGGGCGGGGC GGGTACGGCG TGGTCTACCG CGGCGTGCTC 2520

CCCGACGGCC GCACCGTGGC GGTGAAGAGG CTCGCGAGGC CGCGCGACGG CGACTGCGAG 2580

CGCGAGTTCC GCGCCGAGAT GGAGGTGCTC GCTGACCGGA TGGGGTCGGC GTGGCCGCAC 2640

CCCAACCTCG TCACGCTCTA CGGGTGGTGC CTGTCGGGCT CGGCCAAGAT CCTCGTCTAC 2700

GAGTACCTCG ATGGCGGCAA CCTGGAGGCG CTGATCCCCG ACACGGCGGC GTTCGGGTGG 2760

GCGCGGCGGC TGGACACGGC GATCGGCGTG GCTCGGGCGC TCGTGTTCCT GCACCACGAG 2820

TGCCGCCCCG CGGTGGTGCA CCGCGACGTG AAGGCCAGCA ACGTGCTCCT GGACCGTGAC 2880

GGGCGGGCCA AGGTGACGGA CTTCGGGCTG GCTCGGGTGG TGCGCCCCGG CGACACGCAC 2940

GTGAGCACGG TGGTGGCCGG GACGGTCGGG TACGTGGCCC CCGAGTACGG GCAGACGTGG 3000

CGCGCCACGA CGAAGGGCGA CGTGTACAGC TACGGCGTGC TCCTGATGGA GCTCGCCACG 3060

GGGCGGCGCG CCGTGGACGG CGGCGAGGAG GAGTGCCTGG TGGAGTGGGC ACGGCGGATG 3120

GACAAGGAAG GGTGGCGGTC GAGGAAGGAG GCGGCGGCGG CCGGCGGCAC CGTGTCGTGG 3180

GAGCTCCTGA CGCTCGGCAT GCGGTGCACG GCCGACGCGC CGCCGGAGCG GCCCGACATG 3240

CTGGAAGTGC TCGCCGCGCT GGTCGACGTC GCCAAGGCCG CCGGCGTGCG GCTCGAATTC 3300

ACCTGA 3306

Domain Profile

S: 1     fsednrigeGgfgevyrgelk.ntavavkklkeeadlslkelkqsfltElkvla.....r  54

         fs+d +ig+Gg+g+vyrg l  + +vavk+l+   d +   ++++f +E++vla

Q: 821   FSDDLVIGRGGYGVVYRGVLPdGRTVAVKRLARPRDGD---CEREFRAEMEVLAdrmgsA  877

         7899***************96156*******9988865...5799*******97322224

S: 55    frHdnilellgysaeseklcLvYqymknGsLedrLqcqkgsepLsWpqRlsillGtarai  114

           H+n++ l+g+++ ++   LvY+y+ +G Le+ +    +++   W  Rl+ ++G+ara+

Q: 878   WPHPNLVTLYGWCLSGSAKILVYEYLDGGNLEALI---PDTAAFGWARRLDTAIGVARAL  934

         67*****************************9854...68999*****************

S: 115   efLHeasp.slihgdiksaNiLLDekltpKlgDfglarfapesekqsstvlrtskvrgtl  173

          fLH++ + +++h+d+k++N+LLD + ++K++Dfglar+    + + stv+      gt+

Q: 935   VFLHHECRpAVVHRDVKASNVLLDRDGRAKVTDFGLARVVRPGDTHVSTVV-----AGTV  989

         ***987666*****************************5555555555554.....79**

S: 174   aYlpeefirvgqltvkvDvySfGiVllEvltGlravdedrktkyLkdllkeeieeekvei  233

          Y+++e+ ++ + t+k DvyS+G+ l+E++tG+ravd +++ + L++     +++e+  +

Q: 990   GYVAPEYGQTWRATTKGDVYSYGVLLMELATGRRAVDGGEE-ECLVEW-ARRMDKEGWRS  1047

         ************************************98765.678888.67788888666

S: 234   lekfldkkagkleeellealielalaclaekakkrPtmsqvlel  277

         ++     +a+ +  +++  l++l+++c+a+   +rP+m +vl

Q: 1048  RK-----EAAAAGGTVSWELLTLGMRCTADAPPERPDMLEVLAA  1086

         54.....445556789999********************99876

Domain Sequence
(FASTA)

FSDDLVIGRG GYGVVYRGVL PDGRTVAVKR LARPRDGDCE REFRAEMEVL ADRMGSAWPH 60

PNLVTLYGWC LSGSAKILVY EYLDGGNLEA LIPDTAAFGW ARRLDTAIGV ARALVFLHHE 120

CRPAVVHRDV KASNVLLDRD GRAKVTDFGL ARVVRPGDTH VSTVVAGTVG YVAPEYGQTW 180

RATTKGDVYS YGVLLMELAT GRRAVDGGEE ECLVEWARRM DKEGWRSRKE AAAAGGTVSW 240

ELLTLGMRCT ADAPPERPDM LEVLAA 266

Keyword

Leucine-rich repeat; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Arabidopsis lyrata"; ?>Arabidopsis thaliana"; ?>Brassica rapa"; ?>Glycine max"; ?>Hordeum vulgare"; ?>Oryza indica"; ?>Oryza sativa"; ?>Populus trichocarpa"; ?>Solanum lycopersicum"; ?>Solanum tuberosum"; ?>Sorghum bicolor"; ?>Vitis vinifera"; ?>Zea mays"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR013320	; ConA-like_subgrp.
IPR011009	; Kinase-like_dom.
IPR001611	; Leu-rich_rpt.
IPR013210	; LRR-contain_N2.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00560	; LRR_1; 2.
PF08263	; LRRNT_2; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013