EKS-SEI-00252

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SEI-00252

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/IRAK	213.0	1.1E-62	628	897	270

Status

Unreviewed

Ensembl Protein

Si034100m

UniProt Accession

K4A5E6;

Protein Name

Protein Synonyms/Alias

Gene Name

Si034100m.g

Gene Synonyms/Alias

Si034100m.g;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
Si034100m.g	Si034100m	Si034100m

Organism

Setaria italica

Functional Description

Protein Length

963

Protein Sequence
(FASTA)

MGLVVLAVAV VLAACVPRAC HGMTDSQDTS VLRALMDQWQ NAPPTWGQSD DPCGDSPWEG 60

VTCANDKVIS IKLSTMGIKG VLAADIGQLS GLQSLDLSFN KDLGGVLTPT IGNLKQLTTL 120

ILAGCSFHGT IPDELGSLPK LSYMALNSNQ FSGKIPASLG SLSNLYWFDI ADNQLSGPLP 180

ISTSGGMGLD KLFKTKHFHF NKNQLSGPIP DALFSPEMTL IHLLFDGNKF TGSIPDSLGY 240

VSTLEVVRLD RNSLSGPVPS NLKNLTKVNE LNLANNQLTG TLPDLSGMDL LNYVDLSNNT 300

FDPSPCPAWF WRLPQLSALI IQSGRLYGPV SPRLFSDQQL NQVILDDNAL NGTLDLGRSI 360

SGELSLVSFK NNEFSSVTVT SSYNGTLALA GNPVCEHLPN YCNGTQKGLS VPYSTSLVKC 420

FSGTCPAGQS LSPQSCSCAY PYQGIMYFRA PFFHDVTNGT AFQALESMLW TKLALTPGSV 480

SLQDPFFNSD SYMEVQVKLF PSGSGAYFNR SEVMRIGFDL SNQTFKPPKE FGPYYFIASP 540

YPFPEGGSSS KSKGVIIGIA VGCGVLFVAL AAAAVYAFVQ RRRVQKAKEE LGGPFASWAR 600

SEERGGAPRL KGARWFSYEE LKRSTNNFAE ANELGYGGYG KVYRGMLPTG QFIAIKRAQQ 660

GSMQGGHEFK TEIELLSRVH HKNLVGLVGF CFEQGEQMLV YEFMSGGTLR DSLSGKSGLH 720

LDWKKRLRVA LGAARGLAYL HELADPPIIH RDVKSSNILM DEHLTAKVAD FGLSKLVSDS 780

ERGHVSTQVK GTLGYLDPEY YMSQQLTEKS DVYSFGVVML ELIVAKQPIE KGKYIVREAK 840

RMFDASDAEF CGLKDMIDAR IMNTNHLAAF SKFLQLALRC VDEVATARPS MSEVVKEIEV 900

MLQSEGLSSS STSASTSATE FDVTKGAPRH PYNDPLPKKD KDVSTDSFDY SGGYSFQSRV 960

EPK 963

Nucleotide Sequence
(FASTA)

ATGGGGCTCG TCGTCCTCGC CGTGGCCGTC GTGCTCGCGG CGTGCGTCCC CCGGGCGTGC 60

CATGGCATGA CGGACAGCCA GGACACCTCT GTGCTCAGGG CGTTGATGGA TCAGTGGCAG 120

AACGCGCCGC CGACGTGGGG GCAGTCCGAC GACCCCTGCG GCGATTCGCC ATGGGAGGGA 180

GTGACGTGCG CCAACGACAA AGTGATCTCC ATAAAATTGT CCACCATGGG CATCAAAGGA 240

GTTCTAGCTG CTGACATAGG GCAACTCTCT GGCCTGCAAT CCCTGGACCT GTCATTCAAC 300

AAGGACCTCG GCGGCGTGCT CACTCCGACC ATCGGAAACT TGAAGCAGCT CACCACCTTG 360

ATTCTGGCCG GTTGCAGTTT CCATGGCACC ATCCCGGATG AGCTAGGGAG TCTGCCGAAG 420

CTGTCCTACA TGGCATTGAA CTCAAATCAG TTCTCTGGAA AAATACCGGC TTCGCTGGGC 480

AGTCTCTCCA ACCTCTACTG GTTCGATATC GCTGACAATC AACTGAGCGG ACCCCTGCCG 540

ATTTCGACAA GCGGTGGAAT GGGCCTAGAC AAGCTTTTTA AAACCAAACA CTTTCACTTC 600

AACAAGAACC AATTGTCTGG TCCAATCCCT GACGCTCTCT TCAGCCCGGA GATGACGCTG 660

ATCCATCTGC TCTTTGACGG AAATAAATTC ACCGGGAGTA TCCCAGACTC TCTTGGATAT 720

GTTAGTACAC TTGAAGTTGT ACGCCTGGAC AGAAACTCCC TCTCTGGTCC AGTTCCTTCA 780

AATCTGAAGA ACCTCACCAA AGTAAATGAG CTCAACTTAG CAAACAACCA GCTCACTGGA 840

ACATTGCCAG ATCTATCTGG GATGGATCTT CTCAATTACG TTGATCTGAG CAACAACACA 900

TTTGATCCTT CCCCGTGCCC AGCGTGGTTT TGGAGGCTGC CACAGCTCTC AGCTCTGATC 960

ATACAGTCCG GGAGGCTCTA CGGCCCCGTG TCTCCAAGGC TGTTCAGCGA CCAGCAGTTG 1020

AATCAAGTGA TCCTCGACGA CAACGCGCTC AACGGCACCC TGGACCTGGG CAGGAGCATC 1080

AGCGGCGAGC TGAGCCTCGT GAGCTTCAAG AACAATGAGT TCTCCTCCGT CACGGTGACC 1140

TCCAGCTACA ATGGCACCCT CGCGCTGGCC GGGAACCCGG TGTGCGAGCA CCTGCCCAAC 1200

TACTGCAACG GGACGCAGAA AGGGCTGTCG GTGCCCTACT CGACGAGCCT GGTGAAGTGC 1260

TTCTCGGGGA CGTGCCCGGC GGGGCAGAGC CTGAGCCCGC AGAGCTGCTC GTGCGCGTAC 1320

CCGTACCAGG GGATCATGTA CTTCCGGGCG CCCTTCTTCC ACGACGTGAC CAACGGCACG 1380

GCGTTCCAGG CGCTGGAGAG CATGCTGTGG ACCAAGCTGG CCCTCACCCC GGGCTCCGTC 1440

TCCCTGCAGG ACCCCTTCTT CAACAGCGAC TCCTACATGG AGGTGCAGGT GAAGCTCTTC 1500

CCTTCCGGCA GCGGCGCCTA CTTCAACCGC TCCGAGGTCA TGCGCATCGG CTTCGACCTC 1560

AGCAACCAGA CGTTCAAGCC GCCCAAGGAA TTCGGCCCCT ACTACTTCAT CGCCTCGCCG 1620

TACCCGTTCC CAGAGGGCGG CTCGTCGTCG AAGAGCAAGG GCGTGATCAT CGGGATAGCG 1680

GTCGGCTGCG GCGTCCTGTT CGTGGCTCTC GCCGCGGCGG CCGTCTACGC GTTCGTGCAG 1740

AGGCGGCGAG TGCAGAAGGC CAAGGAGGAG CTCGGCGGCC CTTTCGCGTC GTGGGCTCGG 1800

AGCGAGGAGA GGGGCGGCGC GCCGCGGCTC AAGGGGGCGA GGTGGTTCTC CTACGAGGAG 1860

CTCAAGCGGA GCACCAACAA CTTCGCCGAG GCGAACGAGC TCGGGTACGG GGGCTACGGC 1920

AAGGTGTACA GGGGCATGCT GCCGACGGGG CAGTTCATCG CCATCAAGAG GGCGCAGCAG 1980

GGGTCGATGC AGGGCGGGCA CGAGTTCAAG ACCGAGATCG AGCTGCTCTC CCGCGTGCAC 2040

CACAAGAACC TCGTCGGCCT CGTCGGCTTC TGCTTCGAGC AGGGGGAGCA GATGCTCGTC 2100

TATGAGTTCA TGTCCGGCGG CACGCTGCGC GACAGCCTCT CCGGCAAGAG CGGCCTGCAC 2160

CTCGACTGGA AGAAGCGGCT CCGGGTGGCG CTGGGCGCGG CGCGCGGGCT GGCCTACCTC 2220

CACGAGCTCG CCGACCCGCC CATCATCCAC CGGGACGTCA AGTCCAGCAA CATCCTCATG 2280

GACGAGCACC TCACGGCCAA GGTCGCCGAC TTCGGCCTCT CCAAGCTGGT CTCCGACAGC 2340

GAGAGGGGGC ACGTCAGCAC CCAAGTGAAA GGCACACTGG GGTACCTGGA CCCTGAGTAC 2400

TACATGTCCC AGCAGCTGAC CGAGAAGAGC GACGTGTACA GCTTCGGCGT CGTCATGCTC 2460

GAGCTCATCG TCGCGAAGCA GCCGATCGAG AAGGGCAAGT ACATCGTCCG CGAGGCCAAG 2520

AGGATGTTTG ACGCCTCCGA CGCCGAGTTC TGCGGGCTCA AGGACATGAT CGACGCCAGG 2580

ATCATGAACA CCAACCACCT CGCCGCGTTC AGCAAGTTCC TCCAGCTGGC ACTCCGGTGC 2640

GTCGACGAGG TGGCCACGGC CCGGCCGTCC ATGAGCGAGG TCGTCAAGGA GATCGAGGTG 2700

ATGCTGCAGA GCGAGGGGCT CAGCAGCTCC TCCACGTCCG CCTCGACGTC CGCGACCGAA 2760

TTCGACGTCA CCAAGGGGGC TCCTCGCCAT CCTTACAATG ATCCTCTCCC AAAGAAGGAC 2820

AAGGACGTGA GCACCGACTC GTTTGACTAC AGTGGGGGGT ATTCTTTCCA GTCCAGGGTC 2880

GAACCAAAGT AG 2892

Domain Profile

S: 1     fsednrigeGgfgevyrgel.kntavavkklkeeadlslkelkqsfltElkvlarfrHdn  59

         f+e n +g Gg+g+vyrg l  ++ +a+k+ ++       +  ++f+tE+++l+r++H+n

Q: 628   FAEANELGYGGYGKVYRGMLpTGQFIAIKRAQQGSM----QGGHEFKTEIELLSRVHHKN  683

         78899*************993466889998766543....3456799*************

S: 60    ilellgysaeseklcLvYqymknGsLedrLqcqkgsepLsWpqRlsillGtaraiefLHe  119

         ++ l+g++ e+++  LvY++m++G+L d L+ + g   L W++Rl ++lG+ar++ +LHe

Q: 684   LVGLVGFCFEQGEQMLVYEFMSGGTLRDSLSGKSGL-HLDWKKRLRVALGAARGLAYLHE  742

         *******************************99886.69*********************

S: 120   asp.slihgdiksaNiLLDekltpKlgDfglarfapesekqsstvlrtskvrgtlaYlpe  178

           + ++ih+d+ks+NiL+De+lt+K++Dfgl ++ ++se+   +v    +v+gtl Yl +

Q: 743   LADpPIIHRDVKSSNILMDEHLTAKVADFGLSKLVSDSERG--HVS--TQVKGTLGYLDP  798

         9988*****************************77666654..444..679*********

S: 179   efirvgqltvkvDvySfGiVllEvltGlravdedrktkyLkdllkeeieeekveilekfl  238

         e+  ++qlt k+DvySfG+V+lE++   + +++++  +      + ++ +++   l++ +

Q: 799   EYYMSQQLTEKSDVYSFGVVMLELIVAKQPIEKGKYIVREAKR-MFDASDAEFCGLKDMI  857

         ************************9988877666544333222.2345555666679***

S: 239   dkkagkl.eeellealielalaclaekakkrPtmsqvlel  277

         d+++ +    +  +++++lal+c++e a  rP+ms+v++

Q: 858   DARIMNTnHLAAFSKFLQLALRCVDEVATARPSMSEVVKE  897

         **9877625678899**********************985

Domain Sequence
(FASTA)

FAEANELGYG GYGKVYRGML PTGQFIAIKR AQQGSMQGGH EFKTEIELLS RVHHKNLVGL 60

VGFCFEQGEQ MLVYEFMSGG TLRDSLSGKS GLHLDWKKRL RVALGAARGL AYLHELADPP 120

IIHRDVKSSN ILMDEHLTAK VADFGLSKLV SDSERGHVST QVKGTLGYLD PEYYMSQQLT 180

EKSDVYSFGV VMLELIVAKQ PIEKGKYIVR EAKRMFDASD AEFCGLKDMI DARIMNTNHL 240

AAFSKFLQLA LRCVDEVATA RPSMSEVVKE 270

Keyword

Kinase; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Arabidopsis lyrata"; ?>Arabidopsis thaliana"; ?>Brassica rapa"; ?>Glycine max"; ?>Musa acuminata"; ?>Oryza brachyantha"; ?>Oryza glaberrima"; ?>Oryza indica"; ?>Oryza sativa"; ?>Populus trichocarpa"; ?>Solanum lycopersicum"; ?>Sorghum bicolor"; ?>Vitis vinifera"; ?>Zea mays"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR001611	; Leu-rich_rpt.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00560	; LRR_1; 1.
PF07714	; Pkinase_Tyr; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013