EKS-SEI-00220

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SEI-00220

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/IRAK	216.7	8.6E-64	513	783	271

Status

Unreviewed

Ensembl Protein

Si034221m

UniProt Accession

K4A5R7;

Protein Name

Protein Synonyms/Alias

Gene Name

Si034221m.g

Gene Synonyms/Alias

Si034221m.g;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
Si034221m.g	Si034221m	Si034221m

Organism

Setaria italica

Functional Description

Protein Length

861

Protein Sequence
(FASTA)

MAVLVILLLA TSLPSTALPA FSPAFSYFLA CGASSGVSFP RDSPARNFTP DDKFLASSRA 60

QALTDANANS ASSQLYAAAR ASTSAFSYNL DIHDDSAAFL VLRLHFFPFA ASQSGVSISS 120

ARFAVSVRDA YTRDAYTVLS SFTPPSAGVV KEFFIPAGGP GDFRVMFTPD PGSAAFVNAV 180

ELFPAPAELL WNSTSPVTPV GAAANVATWR QQALETVYRL NVGGPKVSKE NDTLWRTWLP 240

DDPFLFGPPG LSMVNTTSTK IAFIDYTSEV APDIVYKSQR ATNPSAGRAS LQPPLFNITW 300

TFPAEARSNY LVRLHFFCDY EPLNSVVGEG IMFNVFIGPD IGTQDLMPTK TIATQANQQA 360

FYLDYAATAP NTGNLTVSIG KSVKSSSTEG GFLNGLEIMQ LRPSDNLSSS TTKRTVLIVT 420

LSAVLGASVL ACAALCLIVL LRRRRRRHVP RPAPEVEKDG STLPWSPYTQ DSSGWPVEPS 480

SRSGGEGTTG AMQRMGTQLH IPLEELKAAT DNFHERNLIG VGGFGNVYRG VLRDGTRVAV 540

KRATRASKQG LPEFQTEIVV LSRIRHRHLV SLIGYCNEQA EMILVYEYME QGTLRSHLYG 600

PGSGDAPPLS WKQRLEVCIG AARGLHYLHT GYSENIIHRD VKSTNILLGD GFIAKVADFG 660

LSRVGPSFGE THVSTAVKGS FGYLDPEYFK TQQLTDRSDV YSFGVVLFEV LCARPVIDQA 720

LEREQINLAE WAVTWQRRGQ LDKIADPRIA GQVNENSLRK FAETAERCLA DYGQERPSMG 780

DVLWNLEYCL QLQETHVRRD AFEDSGAAGA QFPEDVVVPR WVPSSTSFLT TGDPDETAVS 840

VTDVGAANSK VFSQLSSGEG R 861

Nucleotide Sequence
(FASTA)

ATGGCTGTCC TCGTCATCCT CCTCCTCGCC ACCTCCCTCC CGTCCACCGC CCTCCCCGCC 60

TTCTCCCCGG CCTTCTCCTA CTTCCTCGCC TGCGGCGCCT CCTCCGGCGT CTCCTTCCCG 120

CGCGACAGCC CAGCGCGCAA TTTCACCCCG GACGACAAGT TCTTGGCCTC CTCGCGTGCC 180

CAGGCGCTGA CGGACGCCAA CGCCAACAGC GCCTCCTCAC AGCTCTACGC CGCCGCGCGC 240

GCCTCGACCT CGGCCTTCTC CTACAATCTT GATATCCACG ACGACTCCGC CGCGTTCCTC 300

GTCCTCCGCC TCCACTTCTT CCCTTTCGCC GCCTCGCAAT CCGGCGTAAG CATCTCGTCC 360

GCGCGCTTCG CAGTCTCTGT TCGGGACGCG TACACTCGGG ACGCGTACAC CGTGCTGTCC 420

TCCTTCACGC CGCCGAGCGC CGGCGTCGTC AAGGAGTTCT TCATCCCGGC CGGCGGCCCC 480

GGCGACTTCC GCGTCATGTT CACGCCGGAC CCCGGCTCGG CCGCGTTCGT GAACGCCGTC 540

GAGCTGTTCC CGGCGCCGGC GGAGCTGCTG TGGAACAGCA CGAGCCCGGT GACGCCGGTG 600

GGCGCCGCGG CGAACGTAGC CACGTGGCGG CAGCAAGCGC TGGAGACGGT GTACCGCCTC 660

AACGTGGGCG GCCCCAAGGT GAGCAAGGAG AACGACACGC TGTGGCGGAC ATGGCTCCCC 720

GACGACCCCT TCCTCTTCGG CCCCCCGGGG CTCTCGATGG TGAACACGAC GAGCACCAAG 780

ATCGCGTTCA TCGACTACAC CAGCGAGGTG GCGCCGGACA TTGTCTACAA GTCGCAGCGC 840

GCGACGAACC CGTCGGCGGG CAGGGCATCG CTGCAACCGC CGCTTTTCAA CATCACGTGG 900

ACCTTCCCGG CGGAAGCAAG GTCCAACTAC CTCGTCCGTC TCCACTTCTT CTGCGACTAC 960

GAGCCGTTGA ACAGCGTCGT CGGCGAAGGC ATCATGTTCA ACGTCTTCAT CGGCCCAGAC 1020

ATTGGTACCC AAGACCTGAT GCCGACGAAG ACAATCGCGA CGCAGGCGAA CCAGCAGGCC 1080

TTTTACCTGG ACTACGCGGC CACGGCGCCG AACACCGGGA ACCTCACCGT CAGCATCGGC 1140

AAGTCGGTCA AGAGCAGCTC CACCGAAGGC GGCTTCCTGA ACGGGCTGGA GATCATGCAG 1200

CTGCGACCTT CGGATAATTT GAGCTCGAGC ACCACCAAGA GGACCGTCTT GATCGTCACG 1260

CTCTCGGCCG TGCTCGGCGC CTCCGTCCTC GCGTGCGCCG CGCTCTGCCT GATCGTCCTG 1320

CTGCGGAGGA GGAGACGCCG CCATGTGCCG CGGCCCGCGC CGGAGGTGGA GAAGGATGGC 1380

AGCACCCTGC CTTGGTCGCC CTACACACAG GACAGCTCCG GGTGGCCCGT GGAGCCGTCG 1440

AGCCGGTCCG GCGGCGAGGG CACGACCGGC GCGATGCAGA GGATGGGCAC GCAGCTGCAC 1500

ATCCCGCTGG AGGAGCTCAA GGCGGCCACG GACAACTTCC ACGAGCGCAA CCTGATCGGC 1560

GTGGGCGGGT TCGGCAACGT GTACCGGGGC GTGCTCCGGG ACGGCACCCG CGTGGCGGTG 1620

AAGCGCGCGA CGCGGGCTTC CAAGCAGGGT CTCCCCGAGT TCCAGACGGA GATCGTGGTG 1680

CTGTCCCGCA TCCGGCACCG GCACCTGGTG TCCCTGATCG GCTACTGCAA CGAGCAGGCG 1740

GAGATGATCC TGGTGTACGA GTACATGGAG CAGGGCACGC TGCGGAGCCA CCTGTACGGT 1800

CCCGGCTCCG GCGACGCGCC GCCGCTGTCG TGGAAGCAGC GGCTGGAGGT CTGCATCGGC 1860

GCGGCGCGGG GGCTGCACTA CCTGCACACG GGCTACTCCG AGAACATCAT CCACCGCGAC 1920

GTCAAGTCCA CCAACATCCT CCTCGGCGAC GGCTTCATCG CCAAGGTGGC CGACTTCGGG 1980

CTGTCCCGCG TTGGCCCGTC GTTCGGGGAG ACGCACGTGA GCACGGCGGT GAAGGGCAGC 2040

TTCGGGTACC TGGACCCGGA GTACTTCAAG ACGCAGCAGC TGACGGACCG CTCCGACGTC 2100

TACTCCTTCG GGGTGGTGCT GTTCGAGGTG CTGTGCGCGC GGCCGGTGAT CGACCAGGCG 2160

CTGGAGCGGG AGCAGATCAA CCTGGCGGAG TGGGCCGTGA CGTGGCAGCG GCGCGGGCAG 2220

CTGGACAAGA TCGCCGACCC GCGGATCGCC GGGCAGGTGA ACGAGAACTC GCTGCGCAAG 2280

TTTGCCGAGA CGGCGGAGAG GTGCCTGGCG GACTACGGGC AGGAGCGGCC GTCCATGGGC 2340

GACGTGCTCT GGAACCTCGA GTACTGCCTG CAGCTGCAGG AGACGCACGT GCGCCGGGAC 2400

GCCTTCGAGG ACAGCGGCGC CGCGGGAGCG CAGTTCCCCG AGGACGTGGT GGTGCCGCGA 2460

TGGGTGCCGT CGTCCACGAG CTTCCTGACC ACGGGCGATC CCGACGAGAC CGCCGTCAGC 2520

GTCACCGACG TGGGCGCCGC CAACAGCAAG GTCTTCTCCC AGCTCAGCAG CGGCGAGGGC 2580

CGGTGA 2586

Domain Profile

S: 1     fsednrigeGgfgevyrgelk.ntavavkklkeeadlslkelkqsfltElkvlarfrHdn  59

         f+e n ig Ggfg+vyrg l+ +t vavk+     ++ l     +f+tE+ vl+r+rH +

Q: 513   FHERNLIGVGGFGNVYRGVLRdGTRVAVKRATRASKQGL----PEFQTEIVVLSRIRHRH  568

         8999***************983579****9877665554....5699*************

S: 60    ilellgysaeseklcLvYqymknGsLedrLqcq..kgsepLsWpqRlsillGtaraiefL  117

         ++ l+gy+ e+ ++ LvY+ym+ G+L  +L     ++++pLsW+qRl++++G+ar++++L

Q: 569   LVSLIGYCNEQAEMILVYEYMEQGTLRSHLYGPgsGDAPPLSWKQRLEVCIGAARGLHYL  628

         ******************************98655899**********************

S: 118   Heasp.slihgdiksaNiLLDekltpKlgDfglarfapesekqsstvlrtskvrgtlaYl  176

         H+  + ++ih+d+ks+NiLL + + +K++Dfgl r     ++  +t +    v+g+  Yl

Q: 629   HTGYSeNIIHRDVKSTNILLGDGFIAKVADFGLSR---VGPSFGETHV-STAVKGSFGYL  684

         *99888*****************************...6666777766.4679*******

S: 177   peefirvgqltvkvDvySfGiVllEvltGlravde..drktkyLkdllkeeieeekveil  234

          +e+ +++qlt ++DvySfG+Vl Evl  ++++d+  +r++ +L +     +++++   l

Q: 685   DPEYFKTQQLTDRSDVYSFGVVLFEVLCARPVIDQalEREQINLAEW-AVTWQRRG--QL  741

         ********************************877235677778887.45555555..67

S: 235   ekfldkk.agkleeellealielalaclaekakkrPtmsqvl  275

         +k  d + ag+++e++l +++e a +cla+  ++rP+m +vl

Q: 742   DKIADPRiAGQVNENSLRKFAETAERCLADYGQERPSMGDVL  783

         777777636899**************************9997

Domain Sequence
(FASTA)

FHERNLIGVG GFGNVYRGVL RDGTRVAVKR ATRASKQGLP EFQTEIVVLS RIRHRHLVSL 60

IGYCNEQAEM ILVYEYMEQG TLRSHLYGPG SGDAPPLSWK QRLEVCIGAA RGLHYLHTGY 120

SENIIHRDVK STNILLGDGF IAKVADFGLS RVGPSFGETH VSTAVKGSFG YLDPEYFKTQ 180

QLTDRSDVYS FGVVLFEVLC ARPVIDQALE REQINLAEWA VTWQRRGQLD KIADPRIAGQ 240

VNENSLRKFA ETAERCLADY GQERPSMGDV L 271

Keyword

Kinase; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Hordeum vulgare"; ?>Musa acuminata"; ?>Oryza brachyantha"; ?>Oryza glaberrima"; ?>Oryza indica"; ?>Oryza sativa"; ?>Sorghum bicolor"; ?>Zea mays"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR024788	; Malectin-like_Carb-bd_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF12819	; Malectin_like; 1.
PF07714	; Pkinase_Tyr; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013