EKS-SOL-00979

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SOL-00979

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	329.2	5.0E-98	1142	1458	317

Status

Unreviewed

Ensembl Protein

Solyc03g112950.2.1

UniProt Accession

K4BKE8;

Protein Name

Protein Synonyms/Alias

Gene Name

Solyc03g112950.2

Gene Synonyms/Alias

Solyc03g112950.2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
Solyc03g112950.2	Solyc03g112950.2.1	Solyc03g112950.2.1

Organism

Solanum lycopersicum

Functional Description

Protein Length

1501

Protein Sequence
(FASTA)

MFHEELCQNY SPMEHLLTLG KRSRYLPPRL LLWSLKALHK KLFEDEAYPA QKNEENIFED 60

AYLDSDHEIV HTVWNLVHIC SLSGAGNFGV LVSDFLSRVG IGDPHGVVFH LPIESKSLHD 120

HNFHLGMSIS DELLVAIMRL LKKYLMDDSV KIIDMASQAL RGILSTENGQ RALLSFDSHQ 180

RSLIEVHSKG VNINLVQKLL ADLERKLNAK ALSLKTSAIW KTDGKTFETW ICPLVCALIE 240

YCDDKILRLC QDIVLVKSEV AELLFPHVMV NLSSRKDVDV DLCQLISSQV QENILTEDNK 300

LTKSIQVILD ALNELRLCHV MERGTSSNSS KRENSKQYGR PSSYGSKTRS TPLKAKHQTI 360

TSSVVSLSTL SWEKVYWIHM DYLAVAKSAI ASGAYFTAVL YVEHWCEENF NSLTLGTPDF 420

SHVEILPQHI EILLSAVTHI NEPDSLYGII QSHKLTSQII TFEHEGNWSK ALEYNDLQIR 480

SDPVAQRHSY SPENILHSSD SVVDQMIEKK PYKGLIRSLQ QIGCTHLLDV YCQGLTSQKG 540

RFQHDPEFAE LQYEAAWRSG NWDFSLLYGE SNVLSIQYGG DHFNENLHSC LRALKEGGFN 600

EFQIKLKDSK QELLLSICHA SEESTKYIYQ AIVKLQILYH LGMAWDSRWT SSCRMLDSLK 660

MPTVSSKPVL LSSAELTCLD MDWKRTLKQA QLHMNLLEPF VAFRRVLLQI LNCQNYTIQH 720

LLESAATLRK VSRFSQAASA LHEFKFLCAE VGEHSNLYWL GRLEEAKLLR AQGQHQMAIN 780

LAKYISQNYQ MNENTSDVFR LIGKWLAETR TSNSRTILEK YLKHAVSLAD DCMARGKVST 840

TKRSQMHFHL AHYADALFHS YEERLNSSEW QAAMRLRKHK TKELEALVKR LRSSTKGEKT 900

DCSAKIQELQ KQLAMDKEEA EKLQEDRDNF LSTALDEYKR CLVIGDKYDV RVVFRLVSLW 960

FSLSIKPIVV KSMDSTICEV QSYKFIPLVY QIASRMGSTK EGQGAQNFQF VLVSLIKRLS 1020

IDHPYHTIFQ LLALANGDRI KDKQRSRSSF VVDMDKKVAA ENLLKELSSY HGAVIRQMKQ 1080

MVEIYIKLAE LETKREDTNK KVNLPREIRS IRELELVPVV TANIPIDPSC QYTEGSFPHF 1140

KGLADSVTVM NGINAPKVVE CFGSDGKKYR QLAKSGNDDL RQDAVMEQFF GLVNTFLQNH 1200

RDTWKRRLRI RTYKVVPFTP SAGVLEWVNG TVPLGEYLIG STRDGGAHGR YGAEDWTFMK 1260

CRQHMTVESD KRKAFQEVCV NFRPVMHHFF LERFFHPADW FQKRLAYTRS VAASSMVGYI 1320

VGLGDRHSMN ILVDQATAEV VHIDLGVAFE QGLMLKTPER VPFRLSRDII DGMGITGVEG 1380

VFRRCCEETL SVMRTNKEAL LTIIEVFIHD PLYKWALSPL KALQRQKETD DDLETSLEDS 1440

QQDDYEGNKD AARALMRVKQ KLDGYEEGEM RSVHGQVQQL IHDAIDADRL CHMFPGWGAW 1500

L 1501

Nucleotide Sequence
(FASTA)

ATGTTTCATG AGGAACTATG CCAAAATTAC TCACCTATGG AGCACTTGTT AACTTTAGGG 60

AAACGATCTC GTTACCTTCC GCCAAGATTA CTTCTCTGGA GTTTAAAAGC ATTACACAAG 120

AAATTATTTG AAGATGAAGC TTACCCAGCA CAAAAGAACG AGGAGAACAT TTTTGAAGAT 180

GCATATTTGG ATTCTGACCA TGAAATTGTT CATACAGTCT GGAATCTGGT GCACATATGT 240

AGTTTGAGTG GTGCTGGCAA TTTTGGTGTG CTGGTCTCTG ATTTTTTATC TCGGGTTGGT 300

ATTGGTGATC CCCATGGTGT TGTGTTCCAT CTTCCTATTG AGTCTAAATC TCTACATGAT 360

CATAATTTCC ACCTTGGTAT GAGCATATCA GATGAACTTC TGGTGGCAAT TATGAGGCTT 420

TTAAAGAAAT ATTTGATGGA TGACTCCGTA AAGATAATTG ACATGGCATC TCAAGCTTTG 480

CGGGGGATAC TTTCAACTGA AAATGGTCAG AGGGCTTTGC TATCATTTGA TTCTCATCAG 540

AGATCCCTTA TTGAGGTTCA TTCCAAGGGT GTCAATATCA ACCTGGTGCA GAAACTCCTG 600

GCAGATTTAG AAAGGAAGCT TAATGCTAAG GCACTTTCCC TAAAGACTTC TGCTATATGG 660

AAGACTGATG GAAAAACATT CGAGACATGG ATTTGTCCTC TTGTTTGTGC CCTGATTGAA 720

TATTGTGATG ATAAGATCCT AAGATTGTGT CAAGATATTG TGTTGGTGAA ATCTGAAGTT 780

GCAGAGCTCC TGTTCCCCCA TGTGATGGTC AATTTGTCGA GTAGAAAAGA CGTAGATGTT 840

GATCTTTGTC AGCTGATCTC CTCACAGGTG CAAGAGAACA TTCTTACCGA AGACAATAAG 900

TTGACCAAAT CAATTCAAGT TATCTTAGAT GCGCTTAATG AGCTTCGATT GTGTCACGTG 960

ATGGAAAGAG GCACATCCTC TAATTCCTCT AAGCGAGAAA ATTCAAAGCA ATATGGAAGG 1020

CCTTCTAGCT ATGGATCAAA GACACGCTCC ACGCCTCTGA AGGCAAAGCA TCAGACAATT 1080

ACTTCATCTG TAGTATCACT GTCCACATTA TCATGGGAAA AGGTTTATTG GATTCATATG 1140

GATTATCTTG CTGTTGCAAA GTCTGCAATT GCTTCTGGCG CTTACTTTAC TGCTGTTCTT 1200

TACGTGGAAC ACTGGTGTGA AGAGAATTTC AATTCCCTAA CATTGGGCAC TCCAGATTTC 1260

TCTCATGTTG AGATTCTGCC GCAACACATT GAAATACTTT TATCTGCAGT GACACACATA 1320

AATGAACCAG ACAGCCTCTA TGGAATCATC CAATCCCACA AGTTGACCTC TCAAATTATC 1380

ACATTTGAAC ATGAAGGAAA TTGGAGTAAA GCTCTTGAGT ACAATGATTT ACAAATTAGA 1440

TCTGATCCAG TAGCTCAAAG ACACAGTTAT TCTCCTGAAA ATATTCTTCA TTCATCTGAT 1500

TCAGTAGTAG ATCAGATGAT CGAAAAGAAA CCATATAAGG GCCTTATTAG ATCCTTGCAG 1560

CAAATTGGTT GCACTCATCT TTTGGATGTG TACTGTCAAG GATTGACCTC TCAAAAGGGA 1620

AGGTTCCAAC ATGATCCAGA GTTTGCTGAA CTACAGTATG AAGCTGCTTG GCGTTCTGGA 1680

AATTGGGATT TCTCACTACT TTATGGTGAA TCTAATGTCC TCTCAATTCA GTATGGAGGA 1740

GACCATTTCA ATGAAAATCT CCACAGCTGT TTGCGAGCAT TGAAAGAGGG AGGCTTCAAT 1800

GAATTCCAGA TAAAATTAAA AGATTCCAAG CAGGAGCTTT TGCTGTCTAT CTGTCATGCA 1860

AGCGAGGAGA GCACCAAATA CATTTATCAA GCTATAGTTA AGCTTCAGAT TCTTTATCAC 1920

CTCGGTATGG CATGGGATTC ACGTTGGACT TCATCTTGCA GAATGCTGGA TTCATTGAAG 1980

ATGCCGACGG TTTCATCTAA ACCTGTGCTC CTATCAAGTG CTGAGTTGAC ATGTCTAGAT 2040

ATGGACTGGA AGCGCACTTT AAAGCAAGCA CAGTTACATA TGAATTTGCT GGAGCCATTT 2100

GTGGCATTTA GACGAGTATT GCTTCAGATT TTAAATTGCC AGAATTATAC TATACAACAT 2160

CTGCTTGAAT CTGCAGCCAC TCTCCGCAAG GTGTCTAGGT TTTCGCAGGC TGCTTCAGCT 2220

TTGCATGAAT TTAAGTTTCT TTGTGCAGAA GTAGGAGAAC ATTCCAACCT TTACTGGCTT 2280

GGACGGCTTG AAGAAGCTAA GCTTTTGCGT GCTCAAGGCC AACATCAGAT GGCAATCAAT 2340

CTTGCGAAGT ATATTTCACA GAACTACCAG ATGAACGAAA ATACATCTGA TGTTTTCCGG 2400

TTAATTGGAA AGTGGCTGGC TGAAACACGA ACAAGCAACT CAAGAACTAT ACTAGAGAAA 2460

TACTTGAAGC ATGCAGTCTC TCTAGCTGAT GATTGCATGG CAAGAGGAAA GGTTTCCACC 2520

ACAAAACGAA GTCAAATGCA TTTCCATCTT GCACACTATG CAGATGCTCT TTTTCATAGT 2580

TATGAAGAGA GACTTAATTC CAGTGAATGG CAGGCAGCAA TGCGCTTAAG AAAGCACAAG 2640

ACAAAAGAGC TGGAGGCATT AGTTAAACGA TTAAGAAGTT CAACAAAGGG AGAGAAGACT 2700

GACTGCTCCG CAAAAATACA AGAGTTGCAG AAGCAGCTAG CAATGGACAA AGAAGAGGCT 2760

GAAAAGTTGC AGGAAGACAG GGACAACTTT CTAAGCACCG CGCTTGATGA GTATAAACGC 2820

TGTTTAGTCA TTGGAGATAA ATATGATGTC AGGGTGGTAT TTCGACTTGT TTCCCTGTGG 2880

TTCAGTCTCT CAATTAAACC AATTGTCGTG AAAAGCATGG ACAGCACAAT ATGTGAGGTT 2940

CAGTCTTACA AGTTTATACC ACTAGTATAC CAAATTGCTT CCAGGATGGG AAGCACAAAA 3000

GAAGGCCAGG GAGCTCAAAA CTTCCAGTTT GTTTTGGTTT CTCTCATTAA AAGACTGTCC 3060

ATTGACCATC CATATCATAC AATATTTCAG CTTCTAGCTT TGGCAAATGG TGATAGAATC 3120

AAAGACAAAC AACGCAGCCG AAGTTCTTTT GTGGTTGACA TGGATAAAAA GGTTGCTGCA 3180

GAAAATCTGC TGAAGGAGTT ATCTTCGTAT CATGGAGCGG TCATCAGACA GATGAAACAA 3240

ATGGTTGAGA TCTACATTAA ACTAGCTGAA CTAGAAACAA AGAGGGAGGA TACTAACAAA 3300

AAGGTTAATC TTCCGAGGGA AATTCGCAGC ATCCGAGAGC TTGAACTTGT TCCTGTGGTA 3360

ACAGCCAATA TACCAATTGA CCCGAGTTGT CAATACACTG AAGGATCATT TCCCCACTTT 3420

AAAGGATTGG CAGATTCTGT CACTGTAATG AATGGTATAA ATGCTCCAAA AGTTGTTGAA 3480

TGTTTCGGCT CCGACGGCAA AAAATACCGA CAACTTGCGA AATCTGGCAA TGATGACCTG 3540

AGACAAGATG CTGTGATGGA ACAGTTCTTT GGCTTAGTTA ATACTTTCTT ACAGAATCAT 3600

CGGGACACTT GGAAAAGAAG GCTGAGAATT CGCACTTACA AGGTTGTACC TTTTACTCCA 3660

AGTGCGGGTG TTTTGGAATG GGTGAATGGC ACTGTTCCAC TCGGTGAATA TCTTATAGGC 3720

AGCACTAGAG ATGGAGGTGC CCATGGACGC TATGGAGCAG AAGACTGGAC ATTTATGAAA 3780

TGCCGGCAAC ACATGACTGT GGAAAGTGAC AAGCGGAAGG CCTTCCAGGA AGTCTGCGTT 3840

AACTTCAGGC CTGTTATGCA TCACTTTTTC TTGGAGAGAT TTTTTCATCC AGCTGACTGG 3900

TTTCAAAAGA GGCTTGCTTA TACCAGAAGT GTGGCTGCGA GTTCAATGGT TGGATACATT 3960

GTTGGGCTAG GAGATCGGCA TTCCATGAAT ATCCTTGTAG ATCAAGCCAC TGCAGAAGTT 4020

GTTCACATAG ATCTTGGCGT TGCATTTGAG CAGGGCCTTA TGCTGAAAAC TCCCGAAAGG 4080

GTACCCTTCA GGCTGAGTAG AGACATAATA GATGGCATGG GCATAACTGG GGTGGAAGGG 4140

GTTTTTAGAA GATGCTGTGA GGAAACCCTG TCTGTTATGA GGACAAACAA AGAAGCATTG 4200

CTAACCATTA TTGAGGTCTT TATCCATGAC CCTTTATACA AGTGGGCTTT ATCCCCTCTG 4260

AAGGCTTTGC AACGTCAGAA GGAAACTGAT GATGATCTGG AAACCAGTTT GGAAGACTCT 4320

CAACAAGATG ACTATGAGGG GAACAAGGAT GCTGCTAGAG CCTTGATGCG TGTTAAACAA 4380

AAGTTAGATG GATATGAAGA AGGTGAAATG AGAAGCGTTC ATGGACAGGT TCAACAACTC 4440

ATACACGACG CCATTGATGC TGATCGTTTG TGTCATATGT TTCCTGGATG GGGAGCTTGG 4500

CTATGA 4506

Domain Profile

S: 3     gfderveilaskqkpkklllrGsdgkeypyLv.kgkeDlrqdervlqlfslvNtlLakdk  61

         g++++v++++  ++pk +   Gsdgk+y++L  +g++Dlrqd++++q+f+lvNt+L+++

Q: 1142  GLADSVTVMNGINAPKVVECFGSDGKKYRQLAkSGNDDLRQDAVMEQFFGLVNTFLQNHR  1201

         789*****************************779*************************

S: 62    etsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdls  121

          t +r+L irtykVvp ++  g++ewv++tv+L+e+l     + ++++    +y  +d+

Q: 1202  DTWKRRLRIRTYKVVPFTPSAGVLEWVNGTVPLGEYLI-GSTRDGGAHG---RYGAEDWT  1257

         *************************************6.5677778887...9*******

S: 122   tvqarkpklkhlklslevfkevlenlvpkdllkklllekfpspeewfelrkaytrslAvi  181

          +++r++++    ++ + f+ev+ n+ p  ++++++le f +p++wf++r aytrs+A +

Q: 1258  FMKCRQHMTVESDKR-KAFQEVCVNFRP--VMHHFFLERFFHPADWFQKRLAYTRSVAAS  1314

         ********9999999.************..9*****************************

S: 182   slvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrnivnal  241

         s+vgyi+gLgdrh  n+l+dq t+evvhid+gvafe++ + lk+pe vPFRL r+i++++

Q: 1315  SMVGYIVGLGDRHSMNILVDQATAEVVHIDLGVAFEQGLM-LKTPERVPFRLSRDIIDGM  1373

         ****************************************.*******************

S: 242   gvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk....kkktsketeeel  297

         g+tgveGvfr++ce++l v+r +ke llti+evf++dpl +w        + +ket+ +l

Q: 1374  GITGVEGVFRRCCEETLSVMRTNKEALLTIIEVFIHDPLYKWALsplkALQRQKETDDDL  1433

         *******************************************99988667777777777

S: 298   aekakaealkikkllskvekaenav  322

         +   + ++++  +  ++ ++a  +v

Q: 1434  ETSLEDSQQDDYEGNKDAARALMRV  1458

         7777777776666555555555555

Domain Sequence
(FASTA)

GLADSVTVMN GINAPKVVEC FGSDGKKYRQ LAKSGNDDLR QDAVMEQFFG LVNTFLQNHR 60

DTWKRRLRIR TYKVVPFTPS AGVLEWVNGT VPLGEYLIGS TRDGGAHGRY GAEDWTFMKC 120

RQHMTVESDK RKAFQEVCVN FRPVMHHFFL ERFFHPADWF QKRLAYTRSV AASSMVGYIV 180

GLGDRHSMNI LVDQATAEVV HIDLGVAFEQ GLMLKTPERV PFRLSRDIID GMGITGVEGV 240

FRRCCEETLS VMRTNKEALL TIIEVFIHDP LYKWALSPLK ALQRQKETDD DLETSLEDSQ 300

QDDYEGNKDA ARALMRV 317

Keyword

ATP-binding; Kinase; Nucleotide-binding; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Arabidopsis lyrata"; ?>Arabidopsis thaliana"; ?>Brachypodium distachyon"; ?>Brassica rapa"; ?>Glycine max"; ?>Hordeum vulgare"; ?>Musa acuminata"; ?>Oryza brachyantha"; ?>Oryza glaberrima"; ?>Oryza indica"; ?>Oryza sativa"; ?>Physcomitrella patens"; ?>Populus trichocarpa"; ?>Selaginella moellendorffii"; ?>Setaria italica"; ?>Sorghum bicolor"; ?>Vitis vinifera"; ?>Zea mays"; ?>

Gene Ontology

GO:0004674	; F:protein serine/threonine kinase activity
GO:0000077	; P:DNA damage checkpoint
GO:0006281	; P:DNA repair
GO:0016572	; P:histone phosphorylation
GO:0090399	; P:replicative senescence
GO:0010212	; P:response to ionizing radiation
GO:0000723	; P:telomere maintenance

KEGG

InterPros

IPR015519	; ATM/Tel1.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013