EKS-SOL-01020

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-SOL-01020

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	358.8	3.3E-107	25	316	292

Status

Unreviewed

Ensembl Protein

Solyc07g056350.2.1

UniProt Accession

F8UFC2;

Protein Name

Protein Synonyms/Alias

Mitogen-activated protein kinase 12;

Gene Name

MAPK12

Gene Synonyms/Alias

MAPK12;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
Solyc07g056350.2	Solyc07g056350.2.1	Solyc07g056350.2.1

Organism

Solanum lycopersicum

Functional Description

Protein Length

621

Protein Sequence
(FASTA)

MQPDHRKKSS AEMDFFSEYG DANRYKIQEV IGKGSYGVVC SAIDTHTGEK VAIKKIHDIF 60

EHISDAARIL REIKLLRLLR HPDIVEIKHI MLPPSRRDFK DIYVVFELME SDLHQVIKAN 120

DDLTREHYQF FLYQLLRALK YIHTANVYHR DLKPKNILAN ANCKLKICDF GLARVAFNDT 180

PTTIFWTDYV ATRWYRAPEL CGSFYSKYTP AIDIWSIGCI FAEVLTGKPL FPGKNVVHQL 240

DLMTDLLGTP SMDTISRVRN DKARRYLTSM RKKQPVSFAQ KFPNADPLSL KLLERLLAFD 300

PKDRPTAEEA LADPYFKGLA KSEREPSCKS ISKMEFEFER RRVTKEDLRE LIFREILEYH 360

PQLRKDYLNG VERTNFLYPS AVDQFRKQFA HLEENGGNGV PVVPMDRKHV SLPRSTVVHS 420

NPNPLKEQPI VANMRDRQNG EESCSRNCRD SEGLASSLTR TLQAQPRNAL AAKPGKVVGP 480

GLAYDSGNRE KYDPRSQVRN AVGPPQIMSS VYSYDRSGVV KQERSVETER DMNCHSKPMA 540

PCGMAAKLAP DIAINIDSNP FYMMRAGVTK PDRVDDRITI DTNLLQAKSQ YGGIGVAAAA 600

ATSGAAHRKV GTVQYGMSRM Y 621

Nucleotide Sequence
(FASTA)

ATGCAGCCTG ATCACCGAAA GAAAAGTTCA GCAGAGATGG ACTTCTTCTC TGAATATGGT 60

GATGCAAATA GATACAAAAT TCAAGAAGTC ATAGGGAAAG GAAGCTATGG TGTCGTTTGC 120

TCAGCCATTG ACACGCACAC TGGTGAAAAA GTCGCAATTA AAAAAATTCA TGACATCTTT 180

GAACATATAT CTGATGCGGC ACGGATCCTC CGGGAGATAA AGCTTTTGCG ACTTCTGCGC 240

CATCCTGATA TAGTTGAAAT CAAGCATATT ATGTTGCCAC CTTCGAGGAG GGATTTTAAA 300

GATATTTATG TTGTTTTTGA GCTCATGGAG TCAGATCTAC ACCAAGTTAT CAAGGCTAAT 360

GATGACTTGA CTCGGGAACA TTATCAGTTT TTCCTTTATC AGTTGCTTCG TGCCTTAAAA 420

TATATACACA CAGCTAATGT CTACCATAGA GATTTAAAGC CGAAAAATAT CTTGGCAAAT 480

GCAAATTGCA AGCTCAAGAT CTGTGATTTT GGATTGGCCA GAGTTGCATT CAATGATACA 540

CCTACCACAA TATTTTGGAC GGATTATGTA GCTACTAGAT GGTATAGAGC TCCAGAGTTA 600

TGCGGTTCAT TTTACTCCAA GTATACCCCT GCAATTGATA TATGGAGCAT AGGCTGTATC 660

TTTGCTGAGG TTCTTACGGG GAAGCCGCTC TTTCCTGGAA AAAATGTAGT TCACCAACTG 720

GATTTAATGA CTGATCTGCT TGGAACGCCT TCAATGGATA CAATTTCTCG TGTGCGTAAT 780

GACAAGGCTA GGAGATACCT AACTAGCATG AGAAAGAAGC AGCCTGTTTC TTTTGCTCAG 840

AAATTTCCAA ATGCTGATCC TTTGTCCCTT AAACTTCTTG AAAGATTACT TGCTTTTGAC 900

CCCAAGGACC GACCCACTGC TGAGGAGGCA CTAGCTGATC CTTATTTTAA GGGTCTGGCT 960

AAATCTGAAA GGGAACCATC ATGCAAGTCA ATTTCAAAAA TGGAGTTCGA ATTTGAGAGG 1020

CGAAGAGTGA CGAAGGAGGA TCTCAGGGAA TTAATATTCC GGGAGATACT AGAATATCAT 1080

CCTCAGCTGA GGAAGGATTA CTTGAATGGT GTAGAAAGGA CTAATTTTCT GTATCCGAGT 1140

GCTGTTGATC AATTCAGGAA ACAGTTCGCT CACTTGGAAG AGAACGGTGG TAATGGCGTT 1200

CCAGTGGTTC CGATGGACAG GAAGCATGTC TCTCTTCCAA GGTCTACAGT TGTACATTCA 1260

AATCCAAACC CTTTGAAAGA ACAGCCTATT GTTGCCAATA TGAGAGACCG ACAAAATGGT 1320

GAAGAGTCTT GCAGTAGAAA CTGCAGAGAT TCTGAAGGCC TTGCAAGTAG TCTAACAAGA 1380

ACCCTACAGG CTCAGCCAAG AAATGCTTTA GCAGCCAAAC CAGGAAAAGT TGTTGGTCCC 1440

GGTTTGGCTT ATGATTCGGG AAATAGAGAA AAATATGATC CTAGGTCTCA AGTCAGGAAT 1500

GCAGTAGGCC CCCCTCAGAT TATGTCTTCA GTTTACAGCT ACGACAGAAG TGGGGTGGTG 1560

AAACAAGAAA GGTCTGTTGA GACAGAGAGG GATATGAATT GTCATTCAAA GCCAATGGCA 1620

CCATGTGGAA TGGCTGCTAA GTTAGCCCCA GATATTGCTA TAAATATTGA TAGCAACCCA 1680

TTCTATATGA TGCGAGCTGG AGTTACAAAA CCAGATCGTG TTGATGACCG AATCACCATA 1740

GACACAAACT TATTGCAGGC TAAATCCCAA TATGGTGGAA TTGGAGTTGC GGCGGCAGCA 1800

GCTACTAGTG GTGCAGCTCA TAGGAAAGTA GGGACTGTTC AGTATGGTAT GTCCAGGATG 1860

TACTAG 1866

Domain Profile

S: 1     yeslkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNi  60

         y+ ++ +g+G+ygvv+sa+d++t+e+vaikk+ ++f++  +a r+lRE+kll+ l+h+ i

Q: 25    YKIQEVIGKGSYGVVCSAIDTHTGEKVAIKKIHDIFEHISDAARILREIKLLRLLRHPDI  84

         678899******************************************************

S: 61    iklldvftpeeeleelkdvYlvtelmetdLkkviksq.klsdehiklllyqilrglkylH  119

         +++  ++ p +  +++kd+Y+v+elme+dL++vik +  l+ eh++++lyq+lr+lky+H

Q: 85    VEIKHIMLPPS-RRDFKDIYVVFELMESDLHQVIKANdDLTREHYQFFLYQLLRALKYIH  143

         *******9999.99**********************99**********************

S: 120   sanviHrDlKPsNllvnedcelkildFGlarsadkekekk..lteyvatrwYraPeill.  176

         +anv HrDlKP+N+l n++c+lki+dFGlar+a +++ ++   t+yvatrwYraPe+

Q: 144   TANVYHRDLKPKNILANANCKLKICDFGLARVAFNDTPTTifWTDYVATRWYRAPELCGs  203

         ********************************76665555679**************984

S: 177   slkeytkavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkieseea  236

          +++yt a+DiWs+GCI+aE+ltgkplfpgk+ ++ql++++++lgtps ++++++++++a

Q: 204   FYSKYTPAIDIWSIGCIFAEVLTGKPLFPGKNVVHQLDLMTDLLGTPSMDTISRVRNDKA  263

         5789********************************************************

S: 237   rnyikslpkkkkkdfeelfpkaseealdLleklLvldpdkRisveeaLehpYl  289

         r+y++s+ kk+  +f++ fp+a++ +l+Lle+lL +dp++R ++eeaL+ pY+

Q: 264   RRYLTSMRKKQPVSFAQKFPNADPLSLKLLERLLAFDPKDRPTAEEALADPYF  316

         ****************************************************6

Domain Sequence
(FASTA)

YKIQEVIGKG SYGVVCSAID THTGEKVAIK KIHDIFEHIS DAARILREIK LLRLLRHPDI 60

VEIKHIMLPP SRRDFKDIYV VFELMESDLH QVIKANDDLT REHYQFFLYQ LLRALKYIHT 120

ANVYHRDLKP KNILANANCK LKICDFGLAR VAFNDTPTTI FWTDYVATRW YRAPELCGSF 180

YSKYTPAIDI WSIGCIFAEV LTGKPLFPGK NVVHQLDLMT DLLGTPSMDT ISRVRNDKAR 240

RYLTSMRKKQ PVSFAQKFPN ADPLSLKLLE RLLAFDPKDR PTAEEALADP YF 292

Keyword

ATP-binding; Kinase; Nucleotide-binding; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Arabidopsis lyrata"; ?>Arabidopsis thaliana"; ?>Brachypodium distachyon"; ?>Brassica rapa"; ?>Cyanidioschyzon merolae"; ?>Glycine max"; ?>Hordeum vulgare"; ?>Musa acuminata"; ?>Oryza brachyantha"; ?>Oryza glaberrima"; ?>Oryza indica"; ?>Oryza sativa"; ?>Populus trichocarpa"; ?>Setaria italica"; ?>Solanum tuberosum"; ?>Sorghum bicolor"; ?>Vitis vinifera"; ?>Zea mays"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004707	; F:MAP kinase activity
GO:0000165	; P:MAPK cascade

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR003527	; MAP_kinase_CS.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS01351	; MAPK; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013