EPS-CAE-00006

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-CAE-00006

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	47.1	3.3E-12	131	227	97

Status

Unreviewed

Ensembl Protein

T12B3.1

UniProt Accession

Q9UAX0;

Protein Name

Protein Synonyms/Alias

Protein T12B3.1;

Gene Name

T12B3.1

Gene Synonyms/Alias

T12B3.1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
T12B3.1	T12B3.1	T12B3.1

Organism

Caenorhabditis elegans

Functional Description

Protein Length

446

Protein Sequence
(FASTA)

MPKLWFSGES DNYKLEDEEK ASATYSSLRT GILSLTPGDQ KCRLYCSGPR CRFCIVVTGQ 60

TEIQAIDGLY STWITSDILA MARLQVEHFD SLGIVEKFKT NGIQSVINLQ ESGEHSFCGS 120

GNLTSGFSYD PENLMRNGIY HYNFPLPDFQ ACTPNRLLDI VKVVDFALSH GKIAVHCHAG 180

HGRTGMVIAA WMMYALGMSP SQAVDTVRSR RAKAVQSKEQ VKTLHEFRLL IRNNGGMIIP 240

KNKMTHISEY VAYNQKFISK PESRLYGKIP KIVYIAMRIT LQKMYSSVNF EVENDYRMKI 300

KCEGPLPENK SFDEQLLNAQ LNDDDHEKTH FWYMDQVKNG LSISTISRQL ENEDFRDIIR 360

LLDLFFHSTF HQLTHKEEIF AVLQNWDQTE KDWSPTFWFL LKCIREMPIP LHLALSRLIS 420

KWFLRSEVEI ASRIKHILSS PVTSNE 446

Nucleotide Sequence
(FASTA)

ATGCCGAAAT TATGGTTTTC TGGTGAAAGT GATAATTATA AGTTAGAAGA TGAAGAAAAA 60

GCGTCAGCAA CGTATTCTTC TCTGCGTACT GGTATCCTAA GCCTCACACC TGGTGACCAA 120

AAATGTCGGT TATACTGTAG TGGTCCCCGG TGTAGATTCT GTATCGTAGT AACTGGTCAA 180

ACTGAAATTC AAGCAATAGA TGGTTTATAT TCAACATGGA TAACATCTGA TATTCTTGCA 240

ATGGCACGAC TTCAAGTTGA ACACTTTGAC AGTTTGGGAA TTGTGGAGAA ATTCAAAACA 300

AATGGAATAC AATCAGTCAT AAATCTTCAA GAAAGCGGAG AGCATTCATT CTGTGGAAGC 360

GGTAATCTGA CAAGTGGATT TAGTTATGAT CCAGAGAATT TGATGAGAAA TGGAATTTAT 420

CACTACAATT TCCCACTCCC CGACTTCCAA GCATGCACAC CAAATCGTCT ATTGGATATT 480

GTCAAAGTGG TCGATTTTGC ATTATCCCAT GGAAAAATAG CAGTTCATTG TCATGCGGGT 540

CACGGAAGAA CTGGAATGGT GATTGCTGCA TGGATGATGT ATGCTTTGGG AATGTCTCCG 600

AGTCAAGCAG TTGATACAGT CAGAAGTAGA CGTGCAAAAG CTGTTCAAAG TAAGGAACAG 660

GTGAAAACAT TGCATGAGTT CAGACTTCTA ATAAGGAACA ATGGAGGGAT GATTATTCCT 720

AAAAATAAAA TGACACATAT TTCGGAATAT GTGGCATACA ATCAAAAGTT TATAAGTAAA 780

CCAGAATCTA GATTATACGG TAAAATTCCT AAAATAGTTT ACATTGCAAT GCGAATAACA 840

CTTCAAAAAA TGTATTCATC AGTGAATTTC GAAGTAGAAA ACGATTACCG TATGAAAATT 900

AAATGCGAAG GGCCATTACC TGAAAATAAA TCATTCGATG AACAATTATT AAATGCTCAA 960

TTAAATGATG ATGATCATGA AAAAACTCAT TTTTGGTATA TGGATCAAGT GAAGAATGGG 1020

CTCTCAATAT CTACAATTAG TCGTCAATTA GAGAATGAAG ATTTTCGAGA TATTATACGT 1080

CTTCTTGATT TGTTCTTTCA TTCGACATTT CATCAATTGA CGCATAAAGA GGAAATATTT 1140

GCAGTTTTAC AGAATTGGGA TCAAACTGAA AAGGATTGGT CTCCAACGTT TTGGTTTTTA 1200

TTAAAATGTA TCCGTGAAAT GCCTATTCCT CTTCATTTGG CACTATCACG TCTTATTTCC 1260

AAATGGTTCC TACGTTCTGA AGTGGAAATC GCGTCACGCA TCAAACACAT TTTATCATCA 1320

CCGGTTACTT CAAACGAGTA A 1341

Domain Profile

S: 45    PeylikkgityknipvdDsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlv  104

         Pe l+++gi   n p  D ++    + +d +++++d     +gk+ vHC+aG +R++ ++

Q: 131   PENLMRNGIYHYNFPLPDFQACTPNRLLD-IVKVVDF-ALSHGKIAVHCHAGHGRTGMVI  188

         66666666666666666666655444433.4455554.56789*****************

S: 105   laYLmkveglslsdAieavkrkrpsiepnegfleQLlel  143

          a++m+  g+s s+A+ +v+++r ++ + +++++ L+e+

Q: 189   AAWMMYALGMSPSQAVDTVRSRRAKAVQSKEQVKTLHEF  227

         *************************************98

Domain Sequence
(FASTA)

PENLMRNGIY HYNFPLPDFQ ACTPNRLLDI VKVVDFALSH GKIAVHCHAG HGRTGMVIAA 60

WMMYALGMSP SQAVDTVRSR RAKAVQSKEQ VKTLHEF 97

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

cel:CELE_T12B3.1

;

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.
IPR003595	; Tyr_Pase_cat.

Pfam

PF00782

; DSPc; 1.

SMARTs

SM00404

; PTPc_motif; 1.

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.

Prints

Created Date

20-Feb-2013