EKS-CAE-00266

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAE-00266

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	312.2	4.3E-93	108	386	279

Status

Unreviewed

Ensembl Protein

Y59A8B.23c.1

UniProt Accession

G5EEN4;

Protein Name

Protein Synonyms/Alias

Protein GCK-3, isoform a; STE20-like serine/threonine kinase;

Gene Name

gck-3

Gene Synonyms/Alias

gck-3; Y59A8B.23;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
Y59A8B.23	Y59A8B.23c.1	Y59A8B.23c.1
Y59A8B.23	Y59A8B.23c.2	Y59A8B.23c.2
Y59A8B.23	Y59A8B.23a.2	Y59A8B.23a.2
Y59A8B.23	Y59A8B.23b	Y59A8B.23b
Y59A8B.23	Y59A8B.23a.1	Y59A8B.23a.1

Organism

Caenorhabditis elegans

Functional Description

Protein Length

541

Protein Sequence
(FASTA)

MSSSNLAGNT NTTTTSSAAS AAAAHSAANA STITSEYSTT QTTTGTFNTD TLSSIGSTST 60

LHGSQPSQPP PPPPPQVSSP IAAAAAASAA LVAQLNPADR WPTEPSAYKL DESIGVGATA 120

TVFTAYCLPR NEKVAIKCIN LEKCQTSVDE LSHEIQAMSQ CNHPNVVSYY TSFIAQEELW 180

VVMRLLNCGS MLDILKRKVK AIGKEQAQFG VLDEVSIATV LREVLKGLEY FHLNGQIHRD 240

IKAGNILLAD DGTIQIADFG VSGWLASSGG DLSRQKVRHT FVGTPCWMAP EVMEQVQGYD 300

FKADIWSLGI LAIELATGTA PYHKYPPMKV LMLTLQNDPP TLETNAERKD QYKAYGKSFK 360

TLIRDCLQKD PAKRPTASEL LKYSFFKKGK DKKYLVHTLI ENLASVPVVA HHSSKKVASG 420

KLRKDAHGNW EFEYDSPQES DDDSDLEDEE REKKKKKASA SASGAGAAGA AGGATGGAAS 480

GAPSAQEGGG ATTPCPETLN MVLRVRNQQR ELNDIKFDYT KSADTGTEYF TKSKIYCEAR 540

E 541

Nucleotide Sequence
(FASTA)

ATGAGCTCTT CGAATCTGGC AGGAAACACG AATACTACAA CTACATCATC AGCAGCTTCT 60

GCAGCAGCTG CTCATTCAGC TGCAAATGCT TCAACAATAA CATCAGAATA CTCGACAACA 120

CAGACAACAA CTGGAACATT TAACACTGAT ACATTATCGA GCATCGGATC AACGTCGACA 180

CTTCATGGAT CACAACCATC CCAACCACCA CCACCACCAC CACCTCAAGT ATCATCACCG 240

ATTGCGGCAG CTGCAGCAGC ATCAGCTGCA CTTGTTGCAC AGCTTAATCC GGCCGATCGA 300

TGGCCAACAG AACCGTCGGC TTATAAGTTG GATGAGTCGA TTGGAGTTGG AGCAACTGCT 360

ACCGTTTTTA CTGCCTACTG CCTTCCACGA AACGAGAAAG TCGCCATCAA ATGCATAAAT 420

CTGGAAAAGT GTCAAACATC GGTTGATGAG CTAAGTCATG AGATTCAGGC AATGTCCCAG 480

TGTAATCATC CGAATGTTGT TAGCTATTAT ACATCATTTA TTGCACAAGA AGAACTATGG 540

GTTGTTATGC GTCTACTCAA TTGTGGTTCA ATGCTTGACA TTTTGAAACG CAAAGTTAAG 600

GCAATTGGAA AAGAACAGGC GCAATTCGGT GTCCTCGATG AAGTATCAAT TGCTACAGTA 660

CTCCGTGAAG TACTAAAAGG ACTCGAATAT TTCCATTTAA ACGGACAAAT TCATCGTGAC 720

ATTAAAGCCG GCAACATACT GCTCGCCGAC GATGGAACTA TTCAAATTGC CGATTTTGGA 780

GTATCTGGAT GGCTTGCTTC TTCTGGTGGT GATTTGTCAC GTCAGAAAGT TCGTCACACA 840

TTTGTGGGCA CTCCGTGTTG GATGGCACCA GAAGTAATGG AACAAGTACA AGGATATGAT 900

TTTAAAGCTG ACATTTGGTC ACTTGGAATT CTTGCGATTG AACTTGCCAC CGGAACAGCT 960

CCCTATCATA AATATCCACC AATGAAAGTC CTTATGCTAA CACTTCAAAA TGATCCACCA 1020

ACACTTGAGA CTAATGCTGA GAGAAAAGAT CAATATAAGG CTTATGGAAA ATCGTTTAAG 1080

ACACTGATTC GCGATTGTTT GCAGAAAGAC CCAGCAAAGC GTCCAACAGC CTCCGAACTC 1140

TTGAAATATT CGTTCTTCAA AAAAGGAAAA GACAAGAAAT ATCTGGTACA TACTCTCATT 1200

GAGAATCTCG CTTCAGTTCC AGTAGTCGCC CATCACTCGT CGAAAAAAGT GGCTTCTGGA 1260

AAGTTGCGTA AAGATGCTCA CGGAAATTGG GAATTTGAAT ACGACTCACC ACAAGAAAGT 1320

GATGATGATA GTGATTTGGA GGATGAGGAA CGTGAAAAGA AGAAGAAGAA GGCTAGTGCT 1380

TCAGCATCAG GAGCTGGAGC AGCTGGAGCT GCTGGAGGAG CCACTGGAGG AGCAGCAAGT 1440

GGTGCTCCAA GTGCTCAGGA AGGTGGAGGA GCCACCACTC CGTGTCCAGA GACGTTGAAT 1500

ATGGTGCTCA GAGTTCGGAA TCAACAGCGA GAGCTCAATG ATATCAAGTT TGACTATACA 1560

AAGTCGGCTG ATACTGGTAC GGAATATTTT ACTAAAAGTA AAATATACTG TGAAGCCAGA 1620

GAGTAA 1626

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq.ekleelqkeisvlkklkhpniv  59

         y+l e+ig Ga+++v++a++ +++e+vaik+inlek+ ++++el +ei+++++++hpn+v

Q: 108   YKLDESIGVGATATVFTAYCLPRNEKVAIKCINLEKCqTSVDELSHEIQAMSQCNHPNVV  167

         899**********************************8899*******************

S: 60    eylesflkeeelwlvmeylagGslsdlvk.........eelkselkEeqiayilrevlka  110

         +y++sf+++eelw+vm++l++Gs+ d++k         +++   l+E +ia++lrevlk+

Q: 168   SYYTSFIAQEELWVVMRLLNCGSMLDILKrkvkaigkeQAQFGVLDEVSIATVLREVLKG  227

         *****************************999999988788899****************

S: 111   LeylHskkviHrdikakniLlteegeVkLsdfgvaaqlek.....trkk.rktvvgtpyw  164

         Ley+H +++iHrdika+niLl ++g+++++dfgv+  l++     +r+k r+t+vgtp+w

Q: 228   LEYFHLNGQIHRDIKAGNILLADDGTIQIADFGVSGWLASsggdlSRQKvRHTFVGTPCW  287

         **************************************998888877888**********

S: 165   mAPEviaqeekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklksk.  223

         mAPEv++q  +gYd kaDiwslGI+aiela+g++P+++++p+k+l+++l+n+pp+l+++

Q: 288   MAPEVMEQ-VQGYDFKADIWSLGILAIELATGTAPYHKYPPMKVLMLTLQNDPPTLETNa  346

         *******5.9**********************************************8886

S: 224   ......kkfskefkefvekclqknpekRpsasellkhkFl  257

               k ++k+fk++++ clqk+p+kRp+asellk +F+

Q: 347   erkdqyKAYGKSFKTLIRDCLQKDPAKRPTASELLKYSFF  386

         77777788******************************97

Domain Sequence
(FASTA)

YKLDESIGVG ATATVFTAYC LPRNEKVAIK CINLEKCQTS VDELSHEIQA MSQCNHPNVV 60

SYYTSFIAQE ELWVVMRLLN CGSMLDILKR KVKAIGKEQA QFGVLDEVSI ATVLREVLKG 120

LEYFHLNGQI HRDIKAGNIL LADDGTIQIA DFGVSGWLAS SGGDLSRQKV RHTFVGTPCW 180

MAPEVMEQVQ GYDFKADIWS LGILAIELAT GTAPYHKYPP MKVLMLTLQN DPPTLETNAE 240

RKDQYKAYGK SFKTLIRDCL QKDPAKRPTA SELLKYSFF 279

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity

KEGG

cel:CELE_Y59A8B.23

;

InterPros

IPR011009	; Kinase-like_dom.
IPR024678	; Kinase_OSR1/WNK_CCT.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF12202	; OSR1_C; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013