| Tag | Content |
|---|
| EKPD ID | EKS-SAC-00064 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| CMGC/CDK | 403.0 | 2.0E-121 | 8 | 295 | 288 |
|
| Status | Reviewed |
| Ensembl Protein | YBR160W |
| UniProt Accession | P00546; D6VQF5; |
| Protein Name | Cyclin-dependent kinase 1 |
| Protein Synonyms/Alias | CDK1; Cell division control protein 28; Cell division protein kinase 1; |
| Gene Name | CDC28 |
| Gene Synonyms/Alias | CDC28; CDK1, HSL5, SRM5; YBR160W; YBR1211; |
| Ensembl Information | |
| Organism | Saccharomyces cerevisiae |
| Functional Description | This protein is essential for the completion of thestart, the controlling event, in the cell cycle. More than 200 substrates have been identified. |
| Protein Length | 298 |
Protein Sequence
(FASTA) | | MSGELANYKR LEKVGEGTYG VVYKALDLRP GQGQRVVALK KIRLESEDEG VPSTAIREIS 60 | | LLKELKDDNI VRLYDIVHSD AHKLYLVFEF LDLDLKRYME GIPKDQPLGA DIVKKFMMQL 120 | | CKGIAYCHSH RILHRDLKPQ NLLINKDGNL KLGDFGLARA FGVPLRAYTH EIVTLWYRAP 180 | | EVLLGGKQYS TGVDTWSIGC IFAEMCNRKP IFSGDSEIDQ IFKIFRVLGT PNEAIWPDIV 240 | | YLPDFKPSFP QWRRKDLSQV VPSLDPRGID LLDKLLAYDP INRISARRAA IHPYFQES 298 |
|
Nucleotide Sequence
(FASTA) | | ATGAGCGGTG AATTAGCAAA TTACAAAAGA CTTGAGAAAG TCGGTGAAGG TACATACGGT 60 | | GTTGTTTATA AAGCGTTAGA CTTAAGACCT GGCCAAGGTC AAAGAGTAGT CGCATTGAAG 120 | | AAAATAAGAC TAGAGAGTGA AGACGAGGGT GTTCCCAGTA CAGCCATCAG AGAAATCTCA 180 | | TTATTGAAGG AATTAAAAGA CGATAATATT GTCAGATTAT ACGATATTGT TCACTCTGAT 240 | | GCACACAAGC TATATCTTGT TTTTGAGTTC CTCGATTTGG ACCTGAAAAG ATATATGGAG 300 | | GGTATTCCAA AGGACCAACC GTTAGGAGCT GATATTGTTA AGAAGTTTAT GATGCAACTT 360 | | TGTAAGGGTA TTGCATACTG CCACTCACAC CGTATTCTGC ATCGTGATTT AAAACCGCAG 420 | | AACTTATTGA TTAACAAAGA TGGGAATCTA AAACTAGGTG ATTTTGGCTT AGCGCGTGCT 480 | | TTTGGTGTTC CGTTGAGAGC TTACACACAT GAAATTGTTA CTCTATGGTA TAGAGCTCCG 540 | | GAGGTATTAC TGGGTGGAAA ACAATATAGT ACAGGTGTCG ATACATGGTC CATCGGCTGT 600 | | ATATTTGCCG AAATGTGTAA CAGGAAACCA ATCTTCAGTG GCGATAGTGA GATCGATCAG 660 | | ATTTTCAAGA TATTCAGAGT ATTGGGAACG CCGAATGAAG CTATATGGCC AGATATTGTC 720 | | TACTTGCCTG ATTTCAAGCC AAGCTTTCCT CAATGGCGCA GAAAAGACCT ATCACAAGTG 780 | | GTACCAAGTC TAGATCCACG CGGTATTGAT TTGTTGGACA AACTCCTCGC GTATGACCCT 840 | | ATTAACCGGA TTAGCGCCAG AAGAGCAGCC ATCCACCCCT ACTTCCAAGA ATCATAA 897 |
|
| Domain Profile | S: 1 yeklekigeGtygkvykakdketge...vvAlKkirlekekegvpitalrEisllkelkh 57 | y++lek+geGtyg+vyka d + g+ vvAlKkirle+e+egvp+ta+rEisllkelk | Q: 8 YKRLEKVGEGTYGVVYKALDLRPGQgqrVVALKKIRLESEDEGVPSTAIREISLLKELKD 67 | 899***************99775443349******************************* |
| S: 58 knivkLlevvakdkkklyLvfefleqdLkkllkkkkkk.klsleevkslllqlleglayl 116 | +niv+L+++v++d +klyLvfefl+ dLk++++ +k+ l + vk++++ql +g+ay+ | Q: 68 DNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDqPLGADIVKKFMMQLCKGIAYC 127 | ***********999*******************9988768999***************** |
| S: 117 HsnkilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgak 176 | Hs++ilHRDlKpqNlLi+k+g+lkl+DfGlaraf++pl++yt+e+vTlwYraPe+Llg k | Q: 128 HSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGK 187 | ************************************************************ |
| S: 177 eYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeykk 236 | +Yst vD Ws+gci+ae+++rkp+f+g+seidq+++if++lgtp+e++wp++ lp++k | Q: 188 QYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKP 247 | ************************************************************ |
| S: 237 sfpkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf 284 | sfp++++k+l+++v++l+ +++dll+klla+dp +Risa++a h+yf | Q: 248 SFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYF 295 | ***********************************************9 |
|
Domain Sequence
(FASTA) | | YKRLEKVGEG TYGVVYKALD LRPGQGQRVV ALKKIRLESE DEGVPSTAIR EISLLKELKD 60 | | DNIVRLYDIV HSDAHKLYLV FEFLDLDLKR YMEGIPKDQP LGADIVKKFM MQLCKGIAYC 120 | | HSHRILHRDL KPQNLLINKD GNLKLGDFGL ARAFGVPLRA YTHEIVTLWY RAPEVLLGGK 180 | | QYSTGVDTWS IGCIFAEMCN RKPIFSGDSE IDQIFKIFRV LGTPNEAIWP DIVYLPDFKP 240 | | SFPQWRRKDL SQVVPSLDPR GIDLLDKLLA YDPINRISAR RAAIHPYF 288 |
|
| Keyword | ATP-binding; Cell cycle; Cell division; Complete proteome; Kinase; Mitosis; Nucleotide-binding; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |