| Tag | Content |
|---|
| EKPD ID | EPS-SAC-00013 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| PPP/PP6 | 394.7 | 2.2E-119 | 47 | 240 | 194 |
|
| Status | Reviewed |
| Ensembl Protein | YDL047W |
| UniProt Accession | P20604; D6VRU8; |
| Protein Name | Serine/threonine-protein phosphatase PP1-1 |
| Protein Synonyms/Alias | |
| Gene Name | SIT4 |
| Gene Synonyms/Alias | SIT4; PPH1; YDL047W; D2693; |
| Ensembl Information | |
| Organism | Saccharomyces cerevisiae |
| Functional Description | Involved in the dephosphorylation of the large subunitof RNA polymerase II. Is required in late G1 for normal G1 cyclin expression, bud initiation and expression of certain genes that are periodically expressed during late G1. Associates with the SAP proteins in a cell cycle-dependent manner. |
| Protein Length | 311 |
Protein Sequence
(FASTA) | | MVSRGPDEWL ETIKKCQALT ENEMKQLCEM VKELLMEESN IQPVQTPVTV CGDIHGQFHD 60 | | LLELFRTAGG FPDDINYIFL GDYVDRGYYS LETFTLLMCL KVKYPAKITL VRGNHESRQI 120 | | TQVYGFYEEC LNKYGSTTVW KYCCQVFDFL TLAAIIDGKI LCVHGGLSPE IRMLDQIRVL 180 | | SRAQEVPHEG GFSDLLWSDP DNVEAWQVSP RGAGWLFGSK VAREFNHVNG LNLIARAHQL 240 | | VMEGFKYHFP EKDVVTVWSA PNYCYRCGNV ASVMKVDEDL EPTFKIFSAV PDDYIRESTA 300 | | NHNNQRAGYF L 311 |
|
Nucleotide Sequence
(FASTA) | | ATGGTATCTA GAGGCCCCGA CGAATGGCTT GAAACAATAA AGAAATGCCA GGCGCTAACT 60 | | GAAAACGAGA TGAAACAACT GTGTGAAATG GTGAAAGAAC TTTTGATGGA GGAAAGTAAC 120 | | ATCCAGCCGG TACAGACCCC CGTTACTGTA TGTGGAGACA TACACGGCCA ATTTCATGAC 180 | | TTGTTAGAGC TATTCCGTAC GGCGGGTGGC TTTCCTGACG ATATAAACTA CATTTTTCTC 240 | | GGTGATTACG TGGATCGTGG CTACTATAGT CTGGAAACTT TTACGCTTTT AATGTGTCTG 300 | | AAAGTCAAGT ACCCGGCAAA GATAACTTTG GTCAGAGGAA ACCATGAGTC CAGACAAATT 360 | | ACTCAAGTTT ACGGGTTCTA CGAGGAATGC CTGAATAAGT ACGGATCTAC CACCGTATGG 420 | | AAGTATTGCT GTCAAGTTTT TGATTTCCTG ACGCTGGCCG CTATAATTGA CGGTAAGATC 480 | | TTATGTGTCC ATGGAGGGTT ATCTCCCGAG ATTAGAATGC TCGATCAAAT CAGAGTCTTG 540 | | TCAAGAGCTC AAGAAGTGCC ACACGAGGGT GGGTTCTCGG ACCTGCTTTG GTCAGACCCT 600 | | GACAATGTAG AGGCTTGGCA AGTTTCCCCT CGTGGTGCAG GATGGCTCTT TGGCAGTAAA 660 | | GTTGCTAGAG AGTTTAACCA CGTTAATGGA CTGAACCTTA TTGCCCGGGC TCACCAACTG 720 | | GTTATGGAGG GGTTCAAGTA CCATTTTCCT GAAAAGGACG TTGTAACCGT GTGGTCCGCG 780 | | CCAAATTACT GTTATAGATG TGGTAATGTC GCGAGTGTAA TGAAGGTCGA TGAGGATCTG 840 | | GAACCTACTT TCAAAATTTT CTCGGCTGTT CCCGATGACT ACATAAGAGA ATCCACGGCA 900 | | AACCATAATA ATCAAAGAGC CGGCTATTTC TTATAA 936 |
|
| Domain Profile | S: 1 pvtvcgdihgqfydllklfrtggqvpdt.nyiflgdfvdrgyyslevftlllllkakypa 59 | pvtvcgdihgqf+dll+lfrt+g +pd+ nyiflgd+vdrgyysle+ftll++lk+kypa | Q: 47 PVTVCGDIHGQFHDLLELFRTAGGFPDDiNYIFLGDYVDRGYYSLETFTLLMCLKVKYPA 106 | 9**************************99******************************* |
| S: 60 kitllrgnhesrqitqvygfydeclrkygnanawkyctkvfdlltlaaiidekvlcvhgg 119 | kitl+rgnhesrqitqvygfy+ecl+kyg++++wkyc++vfd+ltlaaiid+k+lcvhgg | Q: 107 KITLVRGNHESRQITQVYGFYEECLNKYGSTTVWKYCCQVFDFLTLAAIIDGKILCVHGG 166 | ************************************************************ |
| S: 120 lspdirtldqirliernqeiphegafcdllwsdpedvetwavsprgagwlfgskvtkefn 179 | lsp+ir+ldqir+++r+qe+pheg+f+dllwsdp++ve+w+vsprgagwlfgskv++efn | Q: 167 LSPEIRMLDQIRVLSRAQEVPHEGGFSDLLWSDPDNVEAWQVSPRGAGWLFGSKVAREFN 226 | ************************************************************ |
| S: 180 hinnldlicrahql 193 | h+n+l+li+rahql | Q: 227 HVNGLNLIARAHQL 240 | *************7 |
|
Domain Sequence
(FASTA) | | PVTVCGDIHG QFHDLLELFR TAGGFPDDIN YIFLGDYVDR GYYSLETFTL LMCLKVKYPA 60 | | KITLVRGNHE SRQITQVYGF YEECLNKYGS TTVWKYCCQV FDFLTLAAII DGKILCVHGG 120 | | LSPEIRMLDQ IRVLSRAQEV PHEGGFSDLL WSDPDNVEAW QVSPRGAGWL FGSKVAREFN 180 | | HVNGLNLIAR AHQL 194 |
|
| Keyword | Cell cycle; Cell division; Complete proteome; Cytoplasm; Hydrolase; Iron; Manganese; Metal-binding; Mitosis; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |