EPS-SAC-00001

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-SAC-00001

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	153.2	2.8E-45	100	343	244

Status

Reviewed

Ensembl Protein

YHR076W

UniProt Accession

P38797; A2TBN2; D3DL26; Q06HN3;

Protein Name

Protein phosphatase 2C homolog 7, mitochondrial

Protein Synonyms/Alias

PP2C-7;

Gene Name

PTC7

Gene Synonyms/Alias

PTC7; YHR076W;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
YHR076W	YHR076W	YHR076W

Organism

Saccharomyces cerevisiae

Functional Description

Protein Length

343

Protein Sequence
(FASTA)

MFANVGFRTL RVSRGPLYGS CSQIISFSKR TFYSSAKSGY QSNNSHGDAY SSGSQSGPFT 60

YKTAVAFQPK DRDDLIYQKL KDSIRSPTGE DNYFVTSNNV HDIFAGVADG VGGWAEHGYD 120

SSAISRELCK KMDEISTALA ENSSKETLLT PKKIIGAAYA KIRDEKVVKV GGTTAIVAHF 180

PSNGKLEVAN LGDSWCGVFR DSKLVFQTKF QTVGFNAPYQ LSIIPEEMLK EAERRGSKYI 240

LNTPRDADEY SFQLKKKDII ILATDGVTDN IATDDIELFL KDNAARTNDE LQLLSQKFVD 300

NVVSLSKDPN YPSVFAQEIS KLTGKNYSGG KEDDITVVVV RVD 343

Nucleotide Sequence
(FASTA)

ATGTTTGCAA ACGTTGGATT TAGAACTTTG AGGGTCTCGA GAGGTCCCCT TTATGGATCC 60

TGCAGTCAAA TCATCAGCTT TTCCAAGAGG ACTTTTTACT CAAGTGCCAA GAGTGGGTAT 120

CAATCGAACA ACAGTCATGG TGATGCGTAT AGTTCAGGTA GCCAATCAGG CCCGTTCACC 180

TATAAAACCG CGGTAGCTTT CCAACCAAAA GACAGAGACG ATCTGATATA CCAAAAACTA 240

AAGGATTCTA TTAGATCACC TACAGGAGAA GACAACTATT TTGTTACATC AAACAACGTT 300

CACGATATTT TTGCCGGTGT CGCAGACGGT GTTGGAGGAT GGGCTGAGCA TGGGTATGAC 360

TCCAGCGCCA TCTCAAGAGA ATTGTGTAAA AAAATGGACG AAATAAGCAC TGCTTTAGCA 420

GAAAATTCAT CCAAAGAAAC GCTTTTAACG CCAAAGAAAA TTATTGGTGC TGCATACGCA 480

AAAATTAGGG ATGAGAAAGT AGTGAAGGTT GGTGGGACAA CAGCCATTGT GGCTCACTTC 540

CCATCTAATG GAAAATTGGA AGTTGCCAAC TTGGGTGATT CTTGGTGTGG AGTCTTCAGA 600

GATTCTAAAC TTGTATTCCA GACAAAGTTT CAAACTGTTG GATTTAATGC TCCTTACCAA 660

TTGTCAATCA TTCCAGAAGA AATGTTGAAA GAGGCCGAAA GAAGGGGTAG CAAGTATATT 720

TTAAACACCC CCAGAGACGC TGATGAATAT AGCTTCCAAT TGAAAAAAAA GGATATTATT 780

ATATTGGCTA CCGATGGTGT AACCGATAAT ATTGCCACAG ATGATATTGA GCTTTTTCTG 840

AAGGATAACG CTGCGAGAAC AAACGATGAG TTACAGCTAT TATCCCAGAA GTTTGTGGAC 900

AATGTTGTCA GTTTAAGCAA GGACCCCAAT TACCCCAGTG TTTTTGCGCA AGAGATTTCT 960

AAGCTAACTG GCAAAAACTA CAGCGGTGGT AAAGAAGACG ATATAACTGT TGTTGTCGTG 1020

AGAGTTGACT AA 1032

Domain Profile

S: 2     dgrlalvvgDvvG....hGleAalimgllrsalrelatagle.........paevlerln  48

          ++++++v+D+vG    hG+++++i+++l+++++e++ta +e         p++++++++

Q: 100   VHDIFAGVADGVGgwaeHGYDSSAISRELCKKMDEISTALAEnssketlltPKKIIGAAY  159

         699*********************************************************

S: 49    ealarnleeeerfatavlaeydpstgkleyanaGhpppllvrpdg...gtkfllvstglp  105

         +++ ++   ++ ++ta++a+ +ps+gkle+an+G++++ ++r+++   +tkf++v++++p

Q: 160   AKIRDEKVVKVGGTTAIVAH-FPSNGKLEVANLGDSWCGVFRDSKlvfQTKFQTVGFNAP  218

         ***55555559*********.**********************99***************

S: 106   ..lGilpe..................adyeeaelqlepgdllllyTDGvtEar.dpdgel  144

           l+i+pe                  +d++e+++ql+++d+++l+TDGvt++  ++d el

Q: 219   yqLSIIPEemlkeaerrgskyilntpRDADEYSFQLKKKDIIILATDGVTDNIaTDDIEL  278

         ************************************************************

S: 145   fgkerllallaeaegesleelldalveelle.....................lgsgeleD  183

         f k++++++++  e   l+ l++++v+++++                     ++sg++eD

Q: 279   FLKDNAARTND--E---LQLLSQKFVDNVVSlskdpnypsvfaqeiskltgkNYSGGKED  333

         ***********..7...99*****************************************

S: 184   Ditllvlrvd  193

         Dit++v+rvd

Q: 334   DITVVVVRVD  343

         ********96

Domain Sequence
(FASTA)

VHDIFAGVAD GVGGWAEHGY DSSAISRELC KKMDEISTAL AENSSKETLL TPKKIIGAAY 60

AKIRDEKVVK VGGTTAIVAH FPSNGKLEVA NLGDSWCGVF RDSKLVFQTK FQTVGFNAPY 120

QLSIIPEEML KEAERRGSKY ILNTPRDADE YSFQLKKKDI IILATDGVTD NIATDDIELF 180

LKDNAARTND ELQLLSQKFV DNVVSLSKDP NYPSVFAQEI SKLTGKNYSG GKEDDITVVV 240

VRVD 244

Keyword

Complete proteome; Hydrolase; Magnesium; Manganese; Metal-binding; Mitochondrion; Protein phosphatase; Reference proteome; Transit peptide.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>