EKS-CAE-00223

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAE-00223

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	301.6	6.1E-90	27	279	253

Status

Unreviewed

Ensembl Protein

ZK524.4

UniProt Accession

G5EFV2;

Protein Name

Protein Synonyms/Alias

Protein ZK524.4;

Gene Name

ZK524.4

Gene Synonyms/Alias

CELE_ZK524.4, ZK524.4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ZK524.4	ZK524.4	ZK524.4

Organism

Caenorhabditis elegans

Functional Description

Protein Length

1016

Protein Sequence
(FASTA)

MSNAPETGAL RRKSSLHIRD TRIAGLYDLE KTIGQGHFAV VKLAKHVFTG EMVAVKIIDK 60

TKMDEASTSQ IMKEVRCMKL VQHANIVRLY EVLDTQTKIF LILELGDYDL HDFIIKHEKG 120

VCESLAQQYF CQIMTAIDYC HQLHVVHRDL KPENVVFFEK LGMVKLTDFG FSNSYEPGEQ 180

LNTSCGSLAY SAPEILLGDS YDAPAVDVWS LGVILYMLVC GRLPFQEAND SETLTKILDC 240

KYSIPDVLSD ECRNLIQSML VREPQKRASL EKIVSTSWVQ AGDRGLSTAI PLIVRHHLPT 300

SAHATIIEQM VAGAIASEED ILRFLENDEY NSVTATYYLL AERVLASYRE EQARELLAKH 360

VEWDDRPDPI SDNSGATTRS NINSRCRSRS NSWRARPCSI LKEESEEELS SYLRSASRQS 420

SRFYPLHDFV SSPRSASRCC SAQLSRQNSE EAMSLKSLDS DSMRPTTFYI PNSAVSTTNP 480

TTPTSAIINR FDEVLSPIDE REGSESDLVR KNLRKIVLNE IVDDSLAGSD EHAIRKSSDS 540

CLHAHHQLLR SASAKRLLRR NSSPSVSMFS GITRDRVSPQ AVQELLDLNR LGGVRGRAAS 600

PESVRSSRSP SPPASSSGRT SPAMSTISSM SRLKVSASNV TNSGMRKLSS SPHLLGICEE 660

TEDGSEVLQS TSSRHLRTLD DRGGRANRYR SASTGLVHLP SRHHSVHATK SSAASLLTTP 720

FVSKPQGITP TPSSSSSTSF VQFTPNTYSA VRSIRPRQAI VSPDILRRYD PHQRFIVRSK 780

RSTSCSSSDA SDDDDGRRLT MLSSKCASKF DEKNKKDDDD EANGGTTGKR GNSGSGTTSL 840

TVTGKQSNNQ SGIAPQSNEK RSTLNDSVLP LRPIPEMTLL DQTLTSPDCA SIRDRILHTS 900

LSTQTMIRKW TEMDSWYGTP PRDYEDRTHL HEKTPWLRCL RRTASSQDLL RESDEKATSE 960

HGNDSGCSTT EKDGEHQCTS PQFIQQNMYN DSKFSFLNTL PMEKVDRWLQ CADFVF 1016

Nucleotide Sequence
(FASTA)

ATGTCAAATG CGCCTGAAAC AGGCGCCCTC CGCCGAAAAT CATCGTTGCA CATCAGGGAT 60

ACACGGATTG CCGGACTCTA TGATTTAGAG AAAACCATCG GCCAAGGGCA TTTTGCAGTG 120

GTTAAGCTGG CAAAACATGT TTTCACTGGA GAAATGGTCG CCGTAAAAAT CATTGATAAA 180

ACAAAGATGG ACGAAGCATC AACGTCACAA ATTATGAAGG AAGTAAGATG TATGAAGCTA 240

GTACAACATG CAAACATTGT TCGGTTATAT GAGGTGCTGG ACACCCAAAC AAAAATATTT 300

CTGATTTTGG AACTCGGCGA TTATGATTTA CATGATTTTA TCATCAAACA CGAAAAAGGA 360

GTGTGCGAGT CGTTAGCCCA GCAGTATTTT TGTCAAATCA TGACTGCCAT CGACTACTGT 420

CATCAGCTTC ACGTTGTTCA TCGCGATTTA AAGCCGGAAA ATGTGGTTTT CTTCGAGAAG 480

CTTGGGATGG TAAAGCTAAC TGATTTTGGA TTCTCAAATA GCTACGAGCC AGGAGAGCAA 540

CTCAACACTT CCTGTGGATC TCTCGCCTAT TCAGCCCCCG AAATTCTTTT AGGAGACTCT 600

TATGATGCAC CAGCTGTTGA TGTATGGTCA TTAGGTGTTA TTTTGTATAT GCTTGTATGT 660

GGTCGACTTC CTTTTCAAGA AGCAAATGAT TCAGAGACTT TGACAAAAAT TCTTGATTGT 720

AAATATTCGA TTCCAGATGT TTTATCCGAT GAATGTAGAA ATTTAATTCA ATCAATGCTT 780

GTTCGTGAGC CACAGAAGAG AGCAAGTCTC GAGAAAATAG TATCAACGTC ATGGGTTCAA 840

GCTGGCGATC GAGGTTTATC AACGGCGATC CCTTTAATAG TTCGACACCA TCTTCCAACC 900

TCCGCCCACG CAACAATAAT CGAACAAATG GTTGCTGGAG CAATAGCATC AGAAGAAGAT 960

ATTCTTCGAT TCTTAGAGAA CGATGAGTAC AATTCAGTCA CAGCGACATA TTATTTGCTT 1020

GCCGAACGAG TTCTCGCTTC GTATCGGGAA GAACAAGCAC GAGAGCTTCT TGCAAAACAT 1080

GTCGAATGGG ATGATCGTCC TGATCCAATA TCTGATAATT CTGGAGCAAC TACAAGGAGC 1140

AATATAAATT CAAGATGTAG ATCTAGATCA AATTCCTGGA GAGCTCGACC TTGCTCGATT 1200

TTAAAAGAAG AGAGCGAAGA AGAGTTGTCT TCTTATCTGA GATCCGCTAG TCGGCAAAGC 1260

AGCAGATTCT ACCCGTTGCA CGATTTTGTG TCGTCACCAC GCAGTGCAAG TCGATGTTGT 1320

AGTGCACAAC TATCACGTCA AAATTCTGAA GAAGCGATGA GCTTGAAGTC TTTGGATAGT 1380

GATTCGATGC GTCCAACCAC ATTCTACATT CCAAATTCTG CTGTTTCGAC GACGAATCCG 1440

ACTACTCCAA CATCAGCCAT CATAAATCGA TTTGATGAAG TTCTTTCACC GATTGATGAA 1500

CGAGAAGGAA GTGAATCGGA TCTTGTTCGA AAGAATTTAC GAAAGATTGT TCTCAATGAG 1560

ATAGTTGACG ATTCATTGGC TGGAAGTGAT GAGCATGCGA TTCGAAAATC CAGTGATAGT 1620

TGTTTGCATG CCCATCATCA GTTGCTGCGT TCGGCATCCG CCAAAAGACT TCTCAGAAGA 1680

AACTCATCAC CCTCCGTCTC AATGTTCTCT GGAATCACAA GAGATCGTGT CAGTCCGCAA 1740

GCTGTGCAGG AACTTCTTGA TTTAAATCGA CTTGGAGGTG TTCGTGGACG AGCTGCCAGT 1800

CCAGAGAGTG TCCGCAGTAG TAGATCACCA TCACCGCCTG CTTCGAGTAG TGGAAGAACA 1860

TCACCAGCAA TGTCCACAAT TTCATCAATG TCACGTCTGA AAGTAAGCGC ATCAAATGTG 1920

ACCAACAGTG GAATGAGAAA ACTCTCGAGT TCTCCACATT TACTTGGAAT TTGTGAAGAG 1980

ACTGAAGATG GAAGCGAAGT TTTACAATCA ACGTCAAGCC GCCATTTGAG AACTTTGGAC 2040

GATCGTGGGG GTCGAGCCAA TCGTTACAGA TCAGCTTCAA CTGGGCTTGT GCATCTGCCG 2100

AGTCGTCATC ACTCAGTTCA CGCCACAAAA AGTTCTGCAG CTTCACTACT CACAACCCCT 2160

TTCGTCTCAA AACCTCAAGG AATAACCCCA ACACCTTCTA GTTCGAGCTC GACATCATTT 2220

GTTCAGTTCA CACCGAATAC CTATAGTGCT GTTAGATCGA TTCGTCCACG TCAAGCTATT 2280

GTTTCACCTG ATATTTTGCG TCGTTACGAT CCTCATCAAC GTTTTATAGT ACGATCAAAG 2340

AGAAGTACAT CTTGCTCTTC CTCTGATGCA TCGGATGATG ATGATGGTAG AAGATTGACA 2400

ATGTTATCTT CGAAATGTGC ATCGAAATTT GATGAGAAAA ATAAAAAAGA CGATGATGAT 2460

GAGGCAAACG GTGGAACAAC GGGAAAACGT GGAAATTCTG GAAGTGGAAC GACATCTCTT 2520

ACTGTAACTG GTAAACAATC TAATAATCAG TCTGGAATAG CTCCACAATC AAATGAGAAA 2580

AGATCAACAC TCAATGATTC GGTACTTCCA CTTCGACCAA TTCCTGAAAT GACTCTGCTT 2640

GATCAGACGC TTACTTCACC GGATTGTGCA TCAATTCGTG ACCGAATCCT ACACACTTCC 2700

TTAAGTACTC AAACTATGAT TCGAAAATGG ACAGAAATGG ATTCATGGTA CGGTACACCA 2760

CCAAGAGATT ACGAAGATCG AACTCACTTA CACGAGAAGA CCCCATGGCT TCGATGCCTT 2820

CGTCGAACTG CATCAAGTCA AGATTTATTA AGAGAAAGTG ACGAAAAAGC CACGAGTGAA 2880

CATGGAAATG ATTCTGGATG TTCTACAACA GAAAAAGACG GAGAACATCA GTGTACATCT 2940

CCACAGTTTA TACAACAAAA TATGTATAAC GATTCGAAAT TCTCATTTCT GAATACTTTG 3000

CCCATGGAGA AAGTTGACCG ATGGCTACAA TGCGCCGATT TTGTATTTTA A 3051

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpni  60

         y+l kt+G+g+f+ Vklakh  t+e+vavKii+k+k++e s+++i++E++++k ++h ni

Q: 27    YDLEKTIGQGHFAVVKLAKHVFTGEMVAVKIIDKTKMDEASTSQIMKEVRCMKLVQHANI  86

         899*********************************************************

S: 61    ikllevietkkklylvleyasggeLfdyieekgr.lkekearklfkqlvsavkYlhskgi  119

         ++l+ev++t++k++l+le+ +  +L d i ++++ + e+ a+++f q+++a++Y+h+ ++

Q: 87    VRLYEVLDTQTKIFLILELGD-YDLHDFIIKHEKgVCESLAQQYFCQIMTAIDYCHQLHV  145

         ******************987.79***9987765499***********************

S: 120   vHrDlKpeNllldkke.nikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpk  178

         vHrDlKpeN+++ +k   +k++DFG++n +++g++l+t+cGs++Y aPe+l g++Y++p+

Q: 146   VHRDLKPENVVFFEKLgMVKLTDFGFSNSYEPGEQLNTSCGSLAYSAPEILLGDSYDAPA  205

         *********99877654*******************************************

S: 179   vDvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpe  238

         vDvWslGv+Ly+lv+g+lPf+e+n +e+l+kil+ k++ip+ ls+e+++L++++Lv++p+

Q: 206   VDVWSLGVILYMLVCGRLPFQEANDSETLTKILDCKYSIPDVLSDECRNLIQSMLVREPQ  265

         ************************************************************

S: 239   kRatieeilkhewl  252

         kRa++e+i++ +w+

Q: 266   KRASLEKIVSTSWV  279

         *************6

Domain Sequence
(FASTA)

YDLEKTIGQG HFAVVKLAKH VFTGEMVAVK IIDKTKMDEA STSQIMKEVR CMKLVQHANI 60

VRLYEVLDTQ TKIFLILELG DYDLHDFIIK HEKGVCESLA QQYFCQIMTA IDYCHQLHVV 120

HRDLKPENVV FFEKLGMVKL TDFGFSNSYE PGEQLNTSCG SLAYSAPEIL LGDSYDAPAV 180

DVWSLGVILY MLVCGRLPFQ EANDSETLTK ILDCKYSIPD VLSDECRNLI QSMLVREPQK 240

RASLEKIVST SWV 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

cel:CELE_ZK524.4

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013