EKS-CAE-00382

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAE-00382

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/VPS15	403.8	5.4E-121	27	285	259

Status

Unreviewed

Ensembl Protein

ZK930.1a

UniProt Accession

Q23669;

Protein Name

Protein Synonyms/Alias

Protein ZK930.1, isoform a;

Gene Name

ZK930.1

Gene Synonyms/Alias

ZK930.1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ZK930.1	ZK930.1a	ZK930.1a
ZK930.1	ZK930.1b	ZK930.1b

Organism

Caenorhabditis elegans

Functional Description

Protein Length

1354

Protein Sequence
(FASTA)

MGNINSLFTT NPSEILPVEV YLNDLSCDAV ENLGSTRFMK VARGRTHEGV FVYKVFVRQD 60

LASLDPFPQR IIDIRKALMK SPNCCPIKKV LVKQKYAVMV RAFQKHTLFD RLSTRPFVVE 120

AEKMWYIFLL FKALSQCETA GVCHGDLKSQ NVLISSTNWL QITDFAPFKP CFLTHDNPSS 180

FTFFFDTSRR QSCYIAPERF ISATEYDEKL RDGQDEWLFG SLTPKMDMFS AGCIVFELLC 240

DRPPFTYSSL CEYRSMNDAD AGNMLLRLIQ DVPAPYRPLL RLLLNRDPSF RISANAVLTG 300

AALKFPHILE SFLFKYLDRF RPLYGTSTSS DPSTDDFSQA LEFSYLEPDD VITKLKREKQ 360

LWWARLSEND ESKSFAFLFV SLITANLRAL RTIQGKTDAI RMLVELSTIS DSSVAIDRIL 420

PYFVHLWMDP ETQVRATAVT AVAELLAPIQ PKTYEESLVF VDYLFPHLNS MSNDSIDSPQ 480

HVLFAIATSL GQFADTAYRF YMAGREIRQA TMYDDEVSTA GEQQQNDDAG ALLHGVSAMF 540

SALCSKEPMV KRCLVESKSL ILLYHFFIKI GNDDTLLRFL CTFLNAKTEW RLRAAFFDSL 600

PVCVQKRSEG MVPLLQLGLQ DGEEHVVVRA LGCIHILIKN ENLDKMSVKK LLDDVLPFLV 660

HPNDWIRSTV CDILLAIDCQ WHNAEVHVKL IPLVSPFVEE SKRGVLTLKS KPVLMSQLVD 720

PIPRTTFNQI IDQSLENTKQ ITMLLEIHFQ TGKPFEAGAG WFNTIFPKIK TETKAGVVEH 780

NDLKAALEAR KRLTASVYSF RKLFERMAET RNTAGMEIYL TRQLGTIDLS SIAHSRVRRK 840

EFTYGGDESA MSSNSKHLTA INIPNHSTER RDTLLLAGEV VIEEERTVTN TPAPYSPVKN 900

TTFDNQVNEM LAHLNELHMR NVNCRPKRPL AASASHPVLS ASPSAGSLGS SSNNNVKGII 960

ITHLHEHSGK ITKLCANRES DLFLSGSTDG TVKVWKTRSV LGEGYGSARS EDTWIPTETS 1020

REKVNSVGWN DQFACSATND GFVRWADVGQ GSARVATQVR IPDAEGPPVY LHCNGPMAIV 1080

RTHHGVLYGI DLRVGASEGP LKRHDIWRKK FQESHGLVTS SAIDPWQQSW MVIGNNSGQK 1140

NLVLYDLRFK EEVLRWESPH QNTQPNRVWA NPVSRQECPE VFVGFSMHGE ISTYELSAQP 1200

LRKRVFWTGG APILSYSAAS NDARKQDSLA TRSLCVCEKT GVVYTGDTRG AIRKWNPTRA 1260

VGCEIISAPP KGRTAYRTIF EENDTSTAPS GASTDPFVIY ERTVLDTEAK ENQKVVPLDS 1320

KPSTYHRTPI TDMMLLNSEL LVSSGYDGVI KIWK 1354

Nucleotide Sequence
(FASTA)

ATGGGTAATA TAAACTCACT TTTCACAACG AATCCGTCGG AAATTCTGCC CGTGGAGGTA 60

TATCTCAACG ATTTGTCATG TGATGCAGTC GAAAATCTTG GGAGCACCCG TTTCATGAAA 120

GTCGCTCGAG GAAGAACGCA TGAAGGCGTC TTTGTGTATA AAGTATTCGT TAGACAAGAT 180

TTGGCGTCAC TGGACCCGTT TCCACAGCGA ATTATCGATA TTCGGAAAGC GCTCATGAAA 240

AGTCCGAATT GTTGTCCTAT CAAAAAGGTT CTTGTAAAAC AAAAGTATGC TGTAATGGTC 300

AGAGCTTTTC AAAAGCACAC GCTCTTCGAT CGATTGAGCA CGAGGCCGTT CGTAGTGGAG 360

GCAGAGAAAA TGTGGTACAT CTTCCTGCTC TTCAAGGCGC TGTCTCAATG TGAAACCGCA 420

GGAGTTTGCC ACGGAGATCT CAAATCACAG AACGTGCTCA TCTCCTCCAC AAACTGGCTA 480

CAAATCACCG ATTTTGCGCC ATTCAAGCCA TGTTTTCTCA CTCACGACAA CCCATCTTCA 540

TTCACATTTT TCTTCGACAC GAGTCGTCGG CAGAGTTGCT ATATTGCACC AGAACGATTC 600

ATTTCTGCTA CGGAATACGA TGAAAAACTT AGGGATGGAC AGGATGAATG GCTTTTCGGG 660

TCGTTAACTC CGAAAATGGA CATGTTCTCG GCTGGTTGCA TCGTCTTTGA GCTTCTCTGT 720

GATCGACCTC CATTCACTTA CAGCTCACTT TGTGAATATC GATCTATGAA TGATGCTGAT 780

GCCGGGAATA TGCTTTTACG ACTAATTCAA GACGTTCCTG CTCCCTACCG CCCACTCCTC 840

CGGCTTCTTC TCAATCGAGA CCCGTCATTC CGTATCTCAG CGAACGCAGT TCTCACCGGA 900

GCCGCTCTCA AATTCCCTCA CATCCTCGAG TCGTTCCTTT TCAAATATCT CGACCGGTTC 960

CGACCGCTTT ATGGTACATC AACGTCGTCC GATCCGTCGA CTGATGATTT CAGTCAGGCT 1020

TTAGAGTTTT CGTATTTGGA GCCAGATGAT GTGATTACGA AGCTGAAACG GGAGAAGCAG 1080

TTGTGGTGGG CACGGCTATC AGAGAATGAT GAATCGAAAT CATTTGCATT CCTCTTTGTA 1140

TCATTGATTA CAGCAAATCT GAGAGCTCTG AGAACAATTC AGGGAAAAAC TGATGCCATT 1200

CGAATGCTCG TCGAACTATC AACAATATCA GATTCCAGCG TGGCCATCGA CAGGATTCTT 1260

CCATACTTTG TTCATCTTTG GATGGATCCG GAAACTCAAG TTCGAGCGAC AGCAGTCACA 1320

GCTGTTGCAG AACTTTTGGC TCCGATTCAA CCGAAAACTT ATGAGGAATC ACTGGTTTTT 1380

GTCGACTATC TCTTCCCCCA TCTAAACTCA ATGTCCAACG ATTCGATTGA TTCTCCCCAA 1440

CACGTGCTCT TCGCAATCGC AACATCTCTC GGACAATTTG CTGATACTGC CTATCGATTC 1500

TACATGGCTG GGCGAGAAAT CCGCCAAGCG ACGATGTATG ATGACGAGGT CTCCACTGCC 1560

GGAGAGCAGC AGCAAAATGA TGACGCCGGG GCGTTGCTCC ACGGAGTTTC TGCAATGTTC 1620

TCCGCGTTGT GTAGCAAGGA ACCAATGGTG AAGCGGTGTC TTGTGGAGAG CAAGTCGCTC 1680

ATATTGCTCT ATCATTTCTT TATTAAAATA GGAAACGACG ATACCCTGCT TCGATTCCTG 1740

TGCACATTTT TGAACGCGAA AACTGAATGG CGGTTACGAG CAGCGTTCTT CGATTCTCTT 1800

CCAGTTTGTG TTCAGAAGCG AAGTGAAGGA ATGGTGCCAC TTCTGCAATT GGGCCTTCAA 1860

GACGGCGAAG AGCACGTTGT AGTCCGTGCT TTAGGATGTA TTCATATTTT GATTAAAAAC 1920

GAGAATTTGG ATAAAATGTC CGTGAAAAAG TTGTTAGATG ATGTTCTGCC GTTTTTAGTT 1980

CATCCAAATG ACTGGATTCG CTCCACCGTT TGTGACATTT TGCTAGCAAT CGATTGTCAA 2040

TGGCATAATG CTGAAGTTCA TGTTAAGCTG ATTCCACTTG TGAGCCCATT CGTTGAGGAA 2100

TCGAAGAGAG GAGTGCTTAC CCTGAAGAGC AAGCCGGTTC TGATGAGCCA GCTCGTCGAC 2160

CCGATCCCAC GGACCACGTT CAATCAGATT ATAGATCAAA GTTTGGAGAA TACCAAGCAA 2220

ATAACTATGC TTTTAGAAAT CCATTTCCAA ACCGGCAAAC CATTCGAAGC GGGGGCTGGA 2280

TGGTTTAACA CGATTTTTCC GAAAATCAAA ACTGAAACGA AAGCGGGAGT TGTAGAGCAT 2340

AATGATTTGA AAGCTGCGTT AGAAGCCAGA AAACGGCTTA CTGCGTCGGT TTATTCGTTT 2400

AGGAAACTTT TTGAACGGAT GGCAGAGACA AGAAATACCG CCGGAATGGA AATCTACTTG 2460

ACTCGCCAAC TCGGAACAAT TGATCTCTCT TCAATTGCTC ACAGTCGAGT ACGACGGAAA 2520

GAGTTCACCT ATGGAGGAGA CGAAAGTGCG ATGAGCTCCA ACTCCAAGCA TCTCACCGCT 2580

ATCAACATTC CGAACCATTC AACAGAACGA CGTGACACTC TTTTGCTTGC TGGTGAAGTG 2640

GTCATTGAAG AAGAACGAAC TGTCACCAAT ACACCGGCTC CTTATTCTCC TGTCAAGAAC 2700

ACCACATTCG ATAATCAAGT GAACGAAATG TTGGCTCATC TCAACGAATT GCACATGAGA 2760

AATGTGAATT GTCGACCGAA ACGTCCATTG GCAGCCAGTG CAAGCCATCC TGTGCTGAGT 2820

GCATCGCCGT CTGCTGGCTC ACTTGGCTCT TCGTCTAATA ATAATGTTAA AGGAATAATT 2880

ATTACGCATC TTCACGAGCA TTCGGGAAAG ATCACAAAAT TGTGCGCCAA CCGAGAATCC 2940

GATCTCTTTC TTAGTGGATC TACGGATGGG ACTGTGAAAG TGTGGAAGAC ACGATCAGTC 3000

CTCGGAGAAG GATACGGGTC GGCGAGAAGT GAGGACACAT GGATTCCAAC CGAAACGAGT 3060

CGCGAGAAGG TGAACTCTGT CGGTTGGAAC GATCAATTCG CATGCTCAGC TACCAACGAC 3120

GGTTTCGTCC GATGGGCTGA TGTTGGACAA GGATCCGCTC GAGTGGCGAC GCAAGTCAGG 3180

ATTCCCGATG CAGAAGGACC ACCTGTGTAT CTCCATTGCA ATGGTCCGAT GGCAATCGTG 3240

AGAACACATC ACGGAGTGCT TTATGGAATT GATTTGAGAG TCGGAGCTTC GGAAGGGCCA 3300

CTCAAGCGAC ATGATATCTG GAGAAAGAAG TTCCAAGAAT CTCACGGCCT CGTCACTTCA 3360

TCTGCTATAG ATCCTTGGCA GCAAAGCTGG ATGGTCATTG GCAATAATTC GGGACAGAAG 3420

AATCTAGTTC TCTATGATTT ACGATTCAAG GAAGAGGTTC TCCGATGGGA GTCTCCACAT 3480

CAGAATACCC AGCCGAACAG AGTATGGGCG AATCCAGTAT CGCGGCAAGA GTGTCCCGAA 3540

GTTTTCGTTG GATTCTCGAT GCATGGCGAG ATTAGTACCT ATGAACTAAG TGCTCAACCT 3600

CTACGAAAAC GAGTTTTCTG GACTGGAGGA GCTCCGATTT TAAGTTATAG TGCCGCGTCA 3660

AACGATGCCC GGAAACAAGA TTCCCTTGCC ACTCGATCTC TATGCGTTTG CGAGAAGACA 3720

GGCGTTGTCT ACACAGGTGA CACACGTGGA GCAATCCGAA AATGGAATCC TACACGAGCT 3780

GTCGGCTGTG AAATCATCTC CGCCCCGCCG AAAGGACGTA CCGCGTATCG AACGATCTTT 3840

GAGGAAAACG ACACATCAAC AGCTCCATCT GGAGCTTCGA CAGATCCATT TGTAATTTAT 3900

GAACGCACCG TGTTGGACAC AGAAGCCAAG GAGAATCAGA AAGTTGTTCC GTTAGATTCA 3960

AAGCCATCCA CCTATCACCG TACCCCGATC ACCGACATGA TGCTTCTCAA CTCTGAACTG 4020

CTCGTCTCTT CTGGCTACGA TGGTGTCATC AAAATTTGGA AATAA 4065

Domain Profile

S: 1     veyvknlgstrflkvakakteeGeivvkvfvkqdptlslesfkqrleelklklakaqncl  60

         +++v+nlgstrf+kva+++t+eG++v+kvfv+qd + sl++f+qr+++++++l+k++nc+

Q: 27    CDAVENLGSTRFMKVARGRTHEGVFVYKVFVRQDLA-SLDPFPQRIIDIRKALMKSPNCC  85

         6899*******************************9.***********************

S: 61    pfqkvlekekaavllrqyvkdnlydrlstrPflneiekkwiafqllkaldqihksgvvhG  120

         p++kvl+k+k+av++r+++k++l+drlstrPf++e+ek+w++f+l+kal+q++++gv+hG

Q: 86    PIKKVLVKQKYAVMVRAFQKHTLFDRLSTRPFVVEAEKMWYIFLLFKALSQCETAGVCHG  145

         ************************************************************

S: 121   diktenvlvtswnWvlltdfasfkPtylpednPadftyffdtsrrrtcyiaPerfvsala  180

         d+k++nvl++s+nW+++tdfa+fkP++l++dnP++ft+ffdtsrr++cyiaPerf+sa++

Q: 146   DLKSQNVLISSTNWLQITDFAPFKPCFLTHDNPSSFTFFFDTSRRQSCYIAPERFISATE  205

         ************************************************************

S: 181   sdeklrdgstelvdldsiqrlrgelkkamdifsaGcvilelftegrplfelsqllayrsg  240

         +deklrdg++e+++        g+l+++md+fsaGc+++el+++ rp+f++s+l++yrs

Q: 206   YDEKLRDGQDEWLF--------GSLTPKMDMFSAGCIVFELLCD-RPPFTYSSLCEYRS-  255

         **************........**********************.**************.

S: 241   eflvekvlekiededlrnlvlqliqlepekrksaedllkk  280

                   ++d+d++n++l+liq+ p++++++ +ll +

Q: 256   ----------MNDADAGNMLLRLIQDVPAPYRPLLRLLLN  285

         ..........*************************99976

Domain Sequence
(FASTA)

CDAVENLGST RFMKVARGRT HEGVFVYKVF VRQDLASLDP FPQRIIDIRK ALMKSPNCCP 60

IKKVLVKQKY AVMVRAFQKH TLFDRLSTRP FVVEAEKMWY IFLLFKALSQ CETAGVCHGD 120

LKSQNVLISS TNWLQITDFA PFKPCFLTHD NPSSFTFFFD TSRRQSCYIA PERFISATEY 180

DEKLRDGQDE WLFGSLTPKM DMFSAGCIVF ELLCDRPPFT YSSLCEYRSM NDADAGNMLL 240

RLIQDVPAPY RPLLRLLLN 259

Keyword

Complete proteome; Reference proteome; Repeat; WD repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0019915	; P:lipid storage

KEGG

cel:CELE_ZK930.1

;

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR021133	; HEAT_type_2.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR015943	; WD40/YVTN_repeat-like_dom.
IPR001680	; WD40_repeat.
IPR017986	; WD40_repeat_dom.

Pfam

PF00069	; Pkinase; 1.
PF00400	; WD40; 2.

SMARTs

SM00320

; WD40; 3.

Prosites

PS50077	; HEAT_REPEAT; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50082	; WD_REPEATS_2; 2.
PS50294	; WD_REPEATS_REGION; 2.

Prints

Created Date

20-Feb-2013