※ G11 family introduction

    G11 family contains a single human gene and belongs to atypical kinase group (1). G11 have been shown to posses the ser/thr kinase activity against alpha casein and histone, but the activity can only be observed in immunoprecipitates from Sf21 insect cells and primate COS cells. G11 contains the ATP-binding ability and the kinase activity remains to be more understood. It is suggested that another kinase binds G11 and perform its kinase activity (2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikinome annotation: Kinase Family G11