※ TAF1 family introduction

    TAF1, transcription initiation factor TFIID subunit 1, is a protein encoding by TAF1 gene and belongs to atypical protein kinase group (1). TAF1 is involved in basal transcription and regulation of promoter recognition and help GTFs form complex assembly and start the transcription. TAF1 contains two protein kinase domains located at N-terminal and C-terminal, and TAF1 also possesses the acetyltransferase and ubiquitin-activating/conjugating activity (2).

>Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikipedia annotation: TAF1